Dbfetch
ID HLA00139; SV 2; standard; DNA; HUM; 3983 BP. XX AC HLA00139; XX SV HLA00139.2 XX DT 20-APR-1996 (Rel. 1.0.0, Created, Version 1) DT 16-JAN-2024 (Rel. 3.55.0, Last Updated, Version 2) XX DE HLA-B*07:07:01:01, Human MHC Class I sequence XX KW Human MHC; HLA; Class I; HLA-B; Allele; HLA-B*07:07:01:01; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-IMGT/HLA Release Version 3.55.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD-IMGT/HLA Database, Distributed under the Creative CC Commons Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/imgt/hla/licence/ for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-3983 RX PUBMED; 9174145. RA Grundschober C, Rufer N, Adami N, Breur-Vriesendorp B, Jeannet M, Roosnek RA E, Tiercy JM; RT "Sequence of a new HLA-B7 variant, B*0707, that differs from the common RT B*0702 allele by one single residue in the peptide binding groove."; RL Tissue Antigens 49:508-511(1997). XX RN [2] RP 1-3983 RX PUBMED; 15896200. RA Vilches C, Sepulveda S, Balas A, Solis R, Aviles MJ, Estefania E, RA Gomez-Lozano N, Vicario JL, Depablo R; RT "Complete coding sequences and haplotypic associations of HLA-B*0707, RT -B*1524, -B*4405, -B*4802, -DRB1*0409, -DRB1*0411, -DRB1*1115, -DRB1*1305, RT and the novel allele -DRB1*0709. Group-specific amplification of cDNA from RT DRB1 alleles associated to DRB3 and DRB4."; RL Tissue Antigens 65:529-538(2005). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC WHO Nomenclature Committee for Factors of the HLA System. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; AJ556171; AJ556171.1. DR EMBL; LT575577; LT575577.1. DR EMBL; OK664989; OK664989.1. DR EMBL; OK664990; OK664990.1. DR EMBL; Z70315; Z70315.1. XX FH Key Location/Qualifiers FH FT source 1..3983 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="Admixed, European, Undefined" FT /cell_line="AN00056" FT /cell_line="C211" FT /cell_line="DAPO" FT /cell_line="MDA0000252" FT /cell_line="MDA0000253" FT CDS join(285..357,486..755,1002..1277,1852..2127,2221..2337, FT 2779..2811,2918..2961) FT /codon_start=1 FT /gene="HLA-B" FT /allele="HLA-B*07:07:01:01" FT /product="MHC Class I HLA-B*07:07:01:01 sequence" FT /translation="MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPR FT FISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRN FT LRGYYNQSEAGSHTLQRMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTA FT AQITQRKWEAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHE FT ATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRY FT TCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGK FT GGSYSQAACSDSAQGSDVSLTA" FT UTR 1..284 FT exon 285..357 FT /number="1" FT intron 358..485 FT /number="1" FT exon 486..755 FT /number="2" FT intron 756..1001 FT /number="2" FT exon 1002..1277 FT /number="3" FT intron 1278..1851 FT /number="3" FT exon 1852..2127 FT /number="4" FT intron 2128..2220 FT /number="4" FT exon 2221..2337 FT /number="5" FT intron 2338..2778 FT /number="5" FT exon 2779..2811 FT /number="6" FT intron 2812..2917 FT /number="6" FT exon 2918..2961 FT /number="7" FT UTR 2962..3983 SQ Sequence 3983 BP; 747 A; 1125 C; 1211 G; 900 T; 0 other; gatcaggacg aagtcccagg tcccggacgg ggctctcagg gtctcaggct ccgagggccg 60 cgtctgcaat ggggaggcgc agcgttgggg attccccact cccctgagtt tcacttcttc 120 tcccaacttg tgtcgggtcc ttcttccagg atactcgtga cgcgtcccca cttcccactc 180 ccattgggta ttggatatct agagaagcca atcagcgtcg ccgcggtccc agttctaaag 240 tccccacgca cccacccgga ctcagagtct cctcagacgc cgagatgctg gtcatggcgc 300 cccgaaccgt cctcctgctg ctctcggcgg ccctggccct gaccgagacc tgggccggtg 360 agtgcgggtc gggagggaaa tggcctctgc cgggaggagc gaggggaccg caggcggggg 420 cgcaggacct gaggagccgc gccgggagga gggtcgggcg ggtctcagcc cctcctcacc 480 cccaggctcc cactccatga ggtatttcta cacctccgtg tcccggcccg gccgcgggga 540 gccccgcttc atctcagtgg gctacgtgga cgacacccag ttcgtgaggt tcgacagcga 600 cgccgcgagt ccgagagagg agccgcgggc gccgtggata gagcaggagg ggccggagta 660 ttgggaccgg aacacacaga tctacaaggc ccaggcacag actgaccgag agagcctgcg 720 gaacctgcgc ggctactaca accagagcga ggccggtgag tgaccccggc ccggggcgca 780 ggtcacgact ccccatcccc cacgtacggc ccgggtcgcc ccgagtctcc gggtccgaga 840 tccgcctccc tgaggccgcg ggacccgccc agaccctcga ccggcgagag ccccaggcgc 900 gtttacccgg tttcattttc agttgaggcc aaaatccccg cgggttggtc ggggcggggc 960 ggggctcggg gggacggggc tgaccgcggg gccggggcca gggtctcaca ccctccagag 1020 gatgtacggc tgcgacgtgg ggccggacgg gcgcctcctc cgcgggcatg accagtacgc 1080 ctacgacggc aaggattaca tcgccctgaa cgaggacctg cgctcctgga ccgccgcgga 1140 cacggcggct cagatcaccc agcgcaagtg ggaggcggcc cgtgaggcgg agcagcggag 1200 agcctacctg gagggcgagt gcgtggagtg gctccgcaga tacctggaga acgggaagga 1260 caagctggag cgcgctggta ccaggggcag tggggagcct tccccatctc ctataggtcg 1320 ccggggatgg cctcccacga gaagaggagg aaaatgggat cagcgctaga atgtcgccct 1380 ccgttgaatg gagaatggca tgagttttcc tgagtttcct ctgagggccc cctcttctct 1440 ctagacaatt aaggaatgac gtctctgagg aaatggaggg gaagacagtc cctagaatac 1500 tgatcagggg tcccctttga cccctgcagc agccttggga accgtgactt ttcctctcag 1560 gccttgttct ctgcctcaca ctcagtgtgt ttggggctct gattccagca cttctgagtc 1620 actttacctc cactcagatc aggagcagaa gtccctgttc cccgctcaga gactcgaact 1680 ttccaatgaa taggagatta tcccaggtgc ctgcgtccag gctggtgtct gggttctgtg 1740 ccccttcccc accccaggtg tcctgtccat tctcaggctg gtcacatggg tggtcctagg 1800 gtgtcccatg aaagatgcaa agcgcctgaa ttttctgact cttcccatca gaccccccaa 1860 agacacacgt gacccaccac cccatctctg accatgaggc caccctgagg tgctgggccc 1920 tgggtttcta ccctgcggag atcacactga cctggcagcg ggatggcgag gaccaaactc 1980 aggacactga gcttgtggag accagaccag caggagatag aaccttccag aagtgggcag 2040 ctgtggtggt gccttctgga gaagagcaga gatacacatg ccatgtacag catgaggggc 2100 tgccgaagcc cctcaccctg agatggggta aggaggggga tgaggggtca tatctcttct 2160 cagggaaagc aggagccctt cagcagggtc agggcccctc atcttcccct cctttcccag 2220 agccgtcttc ccagtccacc gtccccatcg tgggcattgt tgctggcctg gctgtcctag 2280 cagttgtggt catcggagct gtggtcgctg ctgtgatgtg taggaggaag agttcaggta 2340 gggaaggggt gaggggtggg gtctgggttt tcttgtccca ctgggggttt caagccccag 2400 gtagaagtgt tccctgcctc attactggga agcagcatgc acacaggggc taacgcagcc 2460 tgggaccctg tgtgccagca cttactcttt tgtgcagcac atgtgacaat gaaggatgga 2520 tgtatcacct tgatggttgt ggtgttgggg tcctgattcc agcattcatg agtcagggga 2580 aggtccctgc taaggacaga ccttaggagg gcagttggtc caggacccac acttgctttc 2640 ctcgtgtttc ctgatcctgc cctgggtctg tagtcatact tctggaaatt ccttttgggt 2700 ccaagactag gaggttcctc taagatctca tggccctgct tcctcccagt gccctcacag 2760 gacattttct tcccacaggt ggaaaaggag ggagctactc tcaggctgcg tgtaagtggt 2820 gggggtggga gtgtggagga gctcacccac cccataattc ctcctgtccc acgtctcctg 2880 cgggctctga ccaggtcctg tttttgttct actccaggca gcgacagtgc ccagggctct 2940 gatgtgtctc tcacagcttg aaaaggtgag attcttgggg tctagagtgg gtggggtggc 3000 gggtctgggg gtgggtgggg cagaggggaa aggcctgggt aatggggatt ctttgattgg 3060 gatgtttcgc gtgtgtggtg ggctgtttag agtgtcatcg cttaccatga ctaaccagaa 3120 tttgttcatg actgttgttt tctgtagcct gagacagctg tcttgtgagg gactgagatg 3180 caggatttct tcacgcctcc cctttgtgac ttcaagagcc tctggcatct ctttctgcaa 3240 aggcacctga atgtgtctgc gtccctgtta gcataatgtg aggaggtgga gagacagccc 3300 acccttgtgt ccactgtgac ccctgttccc atgctgacct gtgtttcctc cccagtcatc 3360 tttcttgttc cagagaggtg gggctggatg tctccatctc tgtctcaact ttacgtgcac 3420 tgagctgcaa cttcttactt ccctactgaa aataagaatc tgaatataaa tttgttttct 3480 caaatatttg ctatgagagg ttgatggatt aattaaataa gtcaattcct ggaatttgag 3540 agagcaaata aagacctgag aaccttccag aatctgcatg ttcgctgtgc tgagtctgtt 3600 gcaggtgggg tgtggagaag gctgtggggg gccgagtgtg gatggggcct gtgcccattt 3660 ggtgttgagt ccatcatggg ctttatgtgg ttagtcctca gctgggtcac cttcactgct 3720 ccattgtcct tgtcccttca gtggaaactt gtccagtggg agctgtgacc acagaggctc 3780 acacatcgcc cagggcggcc cctgcacacg ggggtctctg tgcattctga gacaaatttt 3840 cagagccatt cacctcctgc tctgcttcta gagctccttt tctgctctgc tcttctgccc 3900 tctctccctg ccctggttct agtgatcttg gtgctgaatc caatcccaac tcatgaatct 3960 gtaaagcaga gtctaattta gac 3983 //