ID   HLA00001   standard; DNA; HUM; 3503 BP.
XX
AC   HLA00001;
XX
DT   01-AUG-1989 (Rel. 1.0.0, Created, Version 1)
DT   16-DEC-1998 (Rel. 1.0.0, Sequence Updated, Version 1)
DT   12-JUL-2013 (Rel. 3.13.0, Current Release, Version 1)
XX
DE   HLA-A*01:01:01:01, Human MHC Class I sequence
XX
KW   Human MHC; HLA; Class I; HLA-A; Allele; A*01:01:01:01;
XX
OS   Homo Sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates;
OC   Catarrhini; Hominidae; Homo.
XX
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CC   Copyrighted by the IMGT/HLA Database, Distributed under the Creative
CC   Commons Attribution-NoDerivs License, see;
CC   http://www.ebi.ac.uk/imgt/hla/licence.html for further details.
CC   --------------------------------------------------------------------------
XX
RN   [1]
RP   1-3503
RX   PUBMED; 3375250.
RA   Parham P, Lomen CE, Lawlor DA, Ways JP, Holmes N, Coppin HL, Salter RD,
RA   Wan AM, Ennis PD;
RT   "Nature of polymorphism in HLA-A, -B, and -C molecules";
RL   Proc Natl Acad Sci U S A 85:4005-9(1988).
XX
RN   [2]
RP   1-3503
RX   PUBMED; 2251137.
RA   Girdlestone J;
RT   "Nucleotide sequence of an HLA-A1 gene";
RL   Nucleic Acids Res 18:6701-6701(1990).
XX
RN   [3]
RP   1-3503
RX   PUBMED; 9349617.
RA   Laforet M, Froelich N, Parissiadis A, Pfeiffer B, Schell A, Faller B,
RA   Woehl-Jaegle ML, Cazenave JP, Tongio MM;
RT   "A nucleotide insertion in exon 4 is responsible for the absence of
RT   expression of an HLA-A*01 allele";
RL   Tissue Antigens 50:347-50(1997).
XX
RN   [4]
RP   1-3503
RX   PUBMED; 15140828.
RA   Stewart CA, Horton R, Allcock RJ, Ashurst JL, Atrazhev AM, Coggill P,
RA   Dunham I, Forbes S, Halls K, Howson JM, Humphray SJ, Hunt S, Mungall AJ,
RA   Osoegawa K, Palmer S, Roberts AN, Rogers J, Sims S, Wang Y, Wilming LG,
RA   Elliott JF, de Jong PJ, Sawcer S, Todd JA, Trowsdale J, Beck S;
RT   "Complete MHC haplotype sequencing for common disease gene mapping";
RL   Genome Res 14:1176-87(2004).
XX
RN   [5]
RP   1-3503
RX   PUBMED; 19735485.
RA   Zhu F, He Y, Zhang W, He J, He J, Xu X, Yan L;
RT   "Analysis of the complete genomic sequence of HLA-A alleles in the Chinese
RT   Han population.";
RL   Int. J. Immunogenetics 36:351-360(2009).
XX
CC   --------------------------------------------------------------------------
CC   The sequence below is the official sequence for A*01:01:01:01, as
CC   approved by the WHO Nomenclature Committee for Factors of the HLA System.
CC   Any cross references may differ from the sequence shown below.
CC   --------------------------------------------------------------------------
XX
DR   EMBL; AJ278305; AJ278305.1.
DR   EMBL; AL645935; AL645935.0.
DR   EMBL; CR759913; CR759913.0.
DR   EMBL; EU445470; EU445470.0.
DR   EMBL; GU812295; GU812295.0.
DR   EMBL; M24043; M24043.1.
DR   EMBL; X55710; X55710.1.
DR   EMBL; Z93949; Z93949.1.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..3503
FT                   /organism="Homo sapiens"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:9606"
FT                   /ethnic="Oriental, Caucasoid"
FT                   /cell_line="7550800303"
FT                   /cell_line="APD"
FT                   /cell_line="B4702"
FT                   /cell_line="COX"
FT                   /cell_line="LCL721"
FT                   /cell_line="MOLT-4"
FT                   /cell_line="PP"
FT   CDS             join(301..373,504..773,1015..1290,1870..2145,2248..2364,
FT                   2807..2839,2982..3029,3199..3203)
FT                   /codon_start=1
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*01:01:01:01"
FT                   /product="MHC Class I HLA-A*01:01:01:01 sequence"
FT                   /translation="MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPR
FT                   FIAVGYVDDTQFVRFDSDAASQKMEPRAPWIEQEGPEYWDQETRNMKAHSQTDRANLGT
FT                   LRGYYNQSEDGSHTIQIMYGCDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMA
FT                   AQITKRKWEAVHAAEQRRVYLEGRCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHE
FT                   ATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRY
FT                   TCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRK
FT                   GGSYTQAASSDSAQGSDVSLTACKV"
FT   UTR             1..300
FT   exon            301..373
FT                   /number="1"
FT   intron          374..503
FT                   /number="1"
FT   exon            504..773
FT                   /number="2"
FT   intron          774..1014
FT                   /number="2"
FT   exon            1015..1290
FT                   /number="3"
FT   intron          1291..1869
FT                   /number="3"
FT   exon            1870..2145
FT                   /number="4"
FT   intron          2146..2247
FT                   /number="4"
FT   exon            2248..2364
FT                   /number="5"
FT   intron          2365..2806
FT                   /number="5"
FT   exon            2807..2839
FT                   /number="6"
FT   intron          2840..2981
FT                   /number="6"
FT   exon            2982..3029
FT                   /number="7"
FT   intron          3030..3198
FT                   /number="7"
FT   exon            3199..3203
FT                   /number="8"
FT   UTR             3204..3503
SQ   Sequence 3503 BP; 666 A; 1012 C; 1070 G; 755 T; 0 other;