ID   AAA59452; SV 1; linear; genomic DNA; STD; HUM; 4149 BP.
XX
PA   M32972.1
XX
DT   10-JUL-1990 (Rel. 24, Created)
DT   14-NOV-2006 (Rel. 89, Last updated, Version 11)
XX
DE   Homo sapiens (human) insulin receptor
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..4149
FT                   /organism="Homo sapiens"
FT                   /map="19p13.3-p13.2"
FT                   /mol_type="genomic DNA"
FT                   /dev_stage="foetus"
FT                   /tissue_type="liver"
FT                   /db_xref="taxon:9606"
FT   CDS             join(M23100.1:1824..1923,M32823.1:174..725,
FT                   M32824.1:114..435,M32825.1:318..466,M32826.1:188..332,
FT                   M32827.1:189..403,M32828.1:277..403,M32829.1:124..374,
FT                   M32830.1:106..273,M32831.1:187..388,M32832.1:123..158,
FT                   M32833.1:161..435,M32834.1:93..232,M32835.1:85..244,
FT                   M32836.1:92..194,M32837.1:261..328,M32838.1:136..380,
FT                   M32839.1:117..227,M32840.1:45..204,M32841.1:115..244,
FT                   M32842.1:101..235,M32972.1:83..437)
FT                   /codon_start=1
FT                   /gene="INSR"
FT                   /product="insulin receptor"
FT                   /note="precursor"
FT                   /db_xref="GOA:P06213"
FT                   /db_xref="HGNC:HGNC:6091"
FT                   /db_xref="InterPro:IPR000494"
FT                   /db_xref="InterPro:IPR000719"
FT                   /db_xref="InterPro:IPR001245"
FT                   /db_xref="InterPro:IPR002011"
FT                   /db_xref="InterPro:IPR003961"
FT                   /db_xref="InterPro:IPR006211"
FT                   /db_xref="InterPro:IPR006212"
FT                   /db_xref="InterPro:IPR008266"
FT                   /db_xref="InterPro:IPR009030"
FT                   /db_xref="InterPro:IPR011009"
FT                   /db_xref="InterPro:IPR013783"
FT                   /db_xref="InterPro:IPR016246"
FT                   /db_xref="InterPro:IPR017441"
FT                   /db_xref="InterPro:IPR020635"
FT                   /db_xref="PDB:1GAG"
FT                   /db_xref="PDB:1I44"
FT                   /db_xref="PDB:1IR3"
FT                   /db_xref="PDB:1IRK"
FT                   /db_xref="PDB:1P14"
FT                   /db_xref="PDB:1RQQ"
FT                   /db_xref="PDB:2AUH"
FT                   /db_xref="PDB:2B4S"
FT                   /db_xref="PDB:2DTG"
FT                   /db_xref="PDB:2HR7"
FT                   /db_xref="PDB:2Z8C"
FT                   /db_xref="PDB:3BU3"
FT                   /db_xref="PDB:3BU5"
FT                   /db_xref="PDB:3BU6"
FT                   /db_xref="PDB:3EKK"
FT                   /db_xref="PDB:3EKN"
FT                   /db_xref="PDB:3ETA"
FT                   /db_xref="PDB:3LOH"
FT                   /db_xref="PDB:3W11"
FT                   /db_xref="PDB:3W12"
FT                   /db_xref="PDB:3W13"
FT                   /db_xref="PDB:3W14"
FT                   /db_xref="UniProtKB/Swiss-Prot:P06213"
FT                   /func_characterised="similar sequence"
FT                   /protein_id="AAA59452.1"
FT                   /translation="MGTGGRRGAAAAPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLT
FT                   RLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFP
FT                   NLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRI
FT                   LDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTI
FT                   CKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCV
FT                   NFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCH
FT                   LLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRR
FT                   SYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYN
FT                   PKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWE
FT                   PYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHP
FT                   GWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSS
FT                   SQIILKWKPPSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKLPSRTWSPPFESEDS
FT                   QKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGTGAE
FT                   DPRPSRKRRSLGDVGNVTVAVPTVAAFPNTSSTSVPTSPEEHRPFEKVVNKESLVISGL
FT                   RHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMW
FT                   QEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRIRATSL
FT                   AGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLG
FT                   PLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSFGMVYEGNARDIIKG
FT                   EAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMA
FT                   HGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCM
FT                   VAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVV
FT                   LWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFL
FT                   EIVNLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMENVPLDRSSHCQREEAGGR
FT                   DGGSSLGFKRSYEEHIPYTHMNGGKKNGRILTLPRSNPS"
XX
SQ   Sequence 4149 BP; 952 A; 1145 C; 1159 G; 893 T; 0 other; 2952102711 CRC32;