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EBI Dbfetch

ID   U56950; SV 1; linear; genomic DNA; STD; HUM; 822 BP.
XX
AC   U56950;
XX
DT   14-DEC-1996 (Rel. 50, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 6)
XX
DE   Human MHC class I chain-related gene A (MICA 011 allele), partial cds.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-822
RX   DOI; 10.1007/s002510050136.
RX   PUBMED; 8781120.
RA   Fodil N., Laloux L., Wanner V., Pellet P., Hauptmann G., Mizuki N.,
RA   Inoko H., Spies T., Theodorou I., Bahram S.;
RT   "Allelic repertoire of the human MHC class I MICA gene";
RL   Immunogenetics 44(5):351-357(1996).
XX
RN   [2]
RP   1-822
RA   Bahram S.;
RT   ;
RL   Submitted (29-APR-1996) to the INSDC.
RL   Siamak Bahram, Basel Institute for Immunology, Grenzacherstrasse 487, Basel
RL   4005, Switzerland
XX
DR   MD5; fc64b2d2b157af1db8cf916471596635.
DR   Ensembl-Gn; ENSG00000183214; homo_sapiens.
DR   Ensembl-Gn; ENSG00000235233; homo_sapiens.
DR   Ensembl-Tr; ENST00000400325; homo_sapiens.
DR   Ensembl-Tr; ENST00000418465; homo_sapiens.
DR   Ensembl-Tr; ENST00000547609; homo_sapiens.
DR   IMGT/LIGM; U56950.
XX
CC   Bahram, S. Proc. Natl. Acad. Sci. USA, 91, 6259-6263, 1994.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..822
FT                   /organism="Homo sapiens"
FT                   /chromosome="6"
FT                   /map="6p21.3"
FT                   /mol_type="genomic DNA"
FT                   /note="The sequence deposited represents exons 2, 3 and 4
FT                   of MICA gene encoding the extracellular alpha1, alpha2 and
FT                   alpha3 domains of the mature protein. The DNA source has
FT                   been derived from genomic DNA of a set of HLA Homozygous
FT                   Typing Cell Lines (HTCLs) provided by the 10th and 11th
FT                   International HLA workshop."
FT                   /db_xref="taxon:9606"
FT   mRNA            <1..>822
FT                   /gene="MICA"
FT                   /note="Allele: MICA 011"
FT   CDS             <1..>822
FT                   /codon_start=1
FT                   /gene="MICA"
FT                   /product="MHC class I chain-related protein A"
FT                   /note="Allele: MICA 011"
FT                   /db_xref="GOA:Q29983"
FT                   /db_xref="HGNC:HGNC:7090"
FT                   /db_xref="IMGT/HLA:MICA*011"
FT                   /db_xref="InterPro:IPR001039"
FT                   /db_xref="InterPro:IPR003597"
FT                   /db_xref="InterPro:IPR007110"
FT                   /db_xref="InterPro:IPR011161"
FT                   /db_xref="InterPro:IPR011162"
FT                   /db_xref="InterPro:IPR013783"
FT                   /db_xref="PDB:1B3J"
FT                   /db_xref="PDB:1HYR"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q29983"
FT                   /protein_id="AAB41070.1"
FT                   /translation="EPHSLRYNLTVLSGDGSVQSGFLAEVHLDGQPFLRCDRQKCRAKP
FT                   QGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNST
FT                   RSSQHFYYDGELFLSQNLETEEWTMPQSSRAQTLAMNVRNFLKEDAVKTKTHYHAMHAD
FT                   CLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVS
FT                   LSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHAVPS"
XX
SQ   Sequence 822 BP; 213 A; 217 C; 237 G; 155 T; 0 other;
     gagccccaca gtcttcgtta taacctcacg gtgctgtccg gggatggatc tgtgcagtca        60
     gggtttctcg ctgaggtaca tctggatggt cagcccttcc tgcgctgtga caggcagaaa       120
     tgcagggcaa agccccaggg acagtgggca gaagatgtcc tgggaaataa gacatgggac       180
     agagagacca gggacttgac agggaacgga aaggacctca ggatgaccct ggctcatatc       240
     aaggaccaga aagaaggctt gcattccctc caggagatta gggtctgtga gatccatgaa       300
     gacaacagca ccaggagctc ccagcatttc tactacgatg gggagctctt cctctcccaa       360
     aacctggaga ctgaggaatg gacaatgccc cagtcctcca gagctcagac cttggccatg       420
     aacgtcagga atttcttgaa ggaagatgcc gtgaagacca agacacacta tcacgctatg       480
     catgcagact gcctgcagga actacggcga tatctaaaat ccggcgtagt cctgaggaga       540
     acagtgcccc ccatggtgaa tgtcacccgc agcgaggcct cagagggcaa cattaccgtg       600
     acatgcaggg cttctggctt ctatccctgg aatatcacac tgagctggcg tcaggatggg       660
     gtatctttga gccacgacac ccagcagtgg ggggatgtcc tgcctgatgg gaatggaacc       720
     taccagacct gggtggccac caggatttgc caaggagagg agcagaggtt cacctgctac       780
     atggaacaca gcgggaatca cagcactcac gctgtgccct ct                          822
//


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