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EBI Dbfetch

ID   U21052; SV 1; linear; mRNA; STD; HUM; 1089 BP.
XX
AC   U21052;
XX
DT   25-MAR-1995 (Rel. 43, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 6)
XX
DE   Human MHC class I antigen heavy chain HLA-B (HLA-B-0701) mRNA, complete
DE   cds.
XX
KW   major histocompatibility complex.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-1089
RX   PUBMED; 8537119.
RA   Smith K.D., Epperson D.F., Lutz C.T.;
RT   "Alloreactive cytotoxic T-lymphocyte-defined HLA-B7 subtypes differ in
RT   peptide antigen presentation";
RL   Immunogenetics 43(1-2):27-37(1996).
XX
RN   [2]
RP   1-1089
RA   Smith K.D.;
RT   ;
RL   Submitted (14-FEB-1995) to the INSDC.
RL   Kelly D. Smith, Pathology, University of Iowa, 200 Hawkins Drive, Iowa
RL   City, IA 52245, USA
XX
DR   MD5; 3758de09ae97457399742f545140f5ed.
DR   Ensembl-Gn; ENSG00000234745; homo_sapiens.
DR   Ensembl-Tr; ENST00000412585; homo_sapiens.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1089
FT                   /organism="Homo sapiens"
FT                   /chromosome="6"
FT                   /isolate="CF"
FT                   /mol_type="mRNA"
FT                   /haplotype="HLA A29/Aw33; B7/B14"
FT                   /cell_line="CF"
FT                   /cell_type="EBV-transformed B cell line"
FT                   /db_xref="taxon:9606"
FT   CDS             1..1089
FT                   /codon_start=1
FT                   /gene="HLA-B"
FT                   /product="MHC class I antigen heavy chain"
FT                   /note="HLA-B-0701 allele"
FT                   /db_xref="GOA:P01889"
FT                   /db_xref="H-InvDB:HIT000218617.14"
FT                   /db_xref="HGNC:HGNC:4932"
FT                   /db_xref="IMGT/HLA:B*07:05:01"
FT                   /db_xref="InterPro:IPR001039"
FT                   /db_xref="InterPro:IPR003006"
FT                   /db_xref="InterPro:IPR003597"
FT                   /db_xref="InterPro:IPR007110"
FT                   /db_xref="InterPro:IPR010579"
FT                   /db_xref="InterPro:IPR011161"
FT                   /db_xref="InterPro:IPR011162"
FT                   /db_xref="InterPro:IPR013783"
FT                   /db_xref="InterPro:IPR027648"
FT                   /db_xref="PDB:3VCL"
FT                   /db_xref="UniProtKB/Swiss-Prot:P01889"
FT                   /protein_id="AAA92563.1"
FT                   /translation="MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPR
FT                   FISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRN
FT                   LRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTA
FT                   AQITQRKWEAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHE
FT                   ATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRY
FT                   TCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGK
FT                   GGSYSQAACSDSAQGSDVSLTA"
FT   exon            <1..73
FT                   /gene="HLA-B"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT   sig_peptide     1..72
FT                   /gene="HLA-B"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT   mat_peptide     73..1086
FT                   /gene="HLA-B"
FT                   /product="MHC class I antigen heavy chain"
FT                   /note="HLA-B-0701 allele"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT   exon            74..343
FT                   /gene="HLA-B"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT   exon            344..619
FT                   /gene="HLA-B"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT   exon            620..895
FT                   /gene="HLA-B"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT   exon            896..1021
FT                   /gene="HLA-B"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT   exon            1022..1054
FT                   /gene="HLA-B"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
FT   exon            1055..>1089
FT                   /gene="HLA-B"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
XX
SQ   Sequence 1089 BP; 220 A; 334 C; 362 G; 173 T; 0 other;
     atgctggtca tggcgccccg aaccgtcctc ctgctgctct cggcggccct ggccctgacc        60
     gagacctggg ccggctccca ctccatgagg tatttctaca cctccgtgtc ccggcccggc       120
     cgcggggagc cccgcttcat ctcagtgggc tacgtggacg acacccagtt cgtgaggttc       180
     gacagcgacg ccgcgagtcc gagagaggag ccgcgggcgc cgtggataga gcaggagggg       240
     ccggagtatt gggaccggaa cacacagatc tacaaggccc aggcacagac tgaccgagag       300
     agcctgcgga acctgcgcgg ctactacaac cagagcgagg ccgggtctca caccctccag       360
     agcatgtacg gctgcgacgt ggggccggac gggcgcctcc tccgcgggca taaccagtac       420
     gcctacgacg gcaaggatta catcgccctg aacgaggacc tgcgctcctg gaccgccgcg       480
     gacacggcgg ctcagatcac ccagcgcaag tgggaggcgg cccgtgaggc ggagcagcgg       540
     agagcctacc tggagggcga gtgcgtggag tggctccgca gatacctgga gaacgggaag       600
     gacaagctgg agcgcgctga ccccccaaag acacacgtga cccaccaccc catctctgac       660
     catgaggcca ccctgaggtg ctgggccctg ggtttctacc ctgcggagat cacactgacc       720
     tggcagcggg atggcgagga ccaaactcag gacactgagc ttgtggagac cagaccagca       780
     ggagatagaa ccttccagaa gtgggcagct gtggtggtgc cttctggaga agagcagaga       840
     tacacatgcc atgtacagca tgaggggctg ccgaagcccc tcaccctgag atgggagccg       900
     tcttcccagt ccaccatccc catcgtgggc attgttgctg gcctggctgt cctagcagtt       960
     gtggtcatcg gagctgtggt cgctgctgtg atgtgtagga ggaagagttc aggtggaaaa      1020
     ggagggagct actctcaggc tgcgtgcagc gacagtgccc agggctctga tgtgtctctc      1080
     acagcttga                                                              1089
//


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