Dbfetch
ID OX175639; SV 1; linear; genomic DNA; STD; HUM; 11541 BP. XX AC OX175639; XX PR Project:PRJEB53990; XX DT 07-JUL-2022 (Rel. 144, Created) DT 14-APR-2023 (Rel. 144, Last updated, Version 3) XX DE Homo sapiens, MICA gene for MHC Class I chain-related gene, cell line DE DKMS-LSL_ID20674381_MICA_1, allele MICA*089:new XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Albrecht V., Schmidt H. A., Klussmeier A., Lange V., Putke K.; RT ; RL Submitted (05-JUL-2022) to the INSDC. RL DKMS LIFE SCIENCE LAB, Research & Development, St. Petersburger Str. 2, RL Saxony, 01069 Dresden, Germany XX DR MD5; 90e1087f39d113b026a185a81eac6f29. XX FH Key Location/Qualifiers FH FT source 1..11541 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /cell_line="DKMS-LSL_ID20674381_MICA_1" FT /db_xref="taxon:9606" FT exon 1..86 FT /gene="MICA" FT /allele="MICA*089:new" FT /number=1 FT CDS join(17..86,6930..7184,7459..7746,8334..8612,8713..8844, FT 11396..11523) FT /codon_start=1 FT /transl_table=1 FT /gene="MICA" FT /allele="MICA*089:new" FT /product="MHC Class I chain-related gene" FT /function="antigen presenting molecule" FT /protein_id="CAH8699459.1" FT /translation="MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSGDGSVQSGF FT LAEVHLDGQPFLRCDRQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIK FT DQKEGLHSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQNLETEEWTMPQSSRAQTLAM FT NVRNFLKEDAMKTKTHYHAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNIT FT VTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFT FT CYMEHSGNHSTHPVPSGKVLVLQSHWQTFHVSAVAAAAIFVIIIFYVCCCKKKTSAAEG FT PELVSLQVLDQHPVGTSDHRDATQLGFQPLMSDLGSTGSTEGA" FT intron 87..6929 FT /gene="MICA" FT /allele="MICA*089:new" FT /number=1 FT exon 6930..7184 FT /gene="MICA" FT /allele="MICA*089:new" FT /number=2 FT intron 7185..7458 FT /gene="MICA" FT /allele="MICA*089:new" FT /number=2 FT exon 7459..7746 FT /gene="MICA" FT /allele="MICA*089:new" FT /number=3 FT intron 7747..8333 FT /gene="MICA" FT /allele="MICA*089:new" FT /number=3 FT exon 8334..8612 FT /gene="MICA" FT /allele="MICA*089:new" FT /number=4 FT intron 8613..8712 FT /gene="MICA" FT /allele="MICA*089:new" FT /number=4 FT exon 8713..8844 FT /gene="MICA" FT /allele="MICA*089:new" FT /number=5 FT intron 8845..11395 FT /gene="MICA" FT /allele="MICA*089:new" FT /number=5 FT exon 11396..11541 FT /gene="MICA" FT /allele="MICA*089:new" FT /number=6 XX SQ Sequence 11541 BP; 2371 A; 2954 C; 2781 G; 3435 T; 0 other; tggcgacgtc ggggccatgg ggctgggccc ggtcttcctg cttctggctg gcatcttccc 60 ttttgcacct ccgggagctg ctgctggtga gtggcgttcc tggcggtcct cggcggagcg 120 ggagcagtgg gacgtttccg ggggtcgggt gggtagcggc gagcgctgtg cggtcagggc 180 ggggctcctg tgcgctgtcg gtggcgcagg gagctggacg cggcccgtta ccgccacact 240 tcagccctgc ttccccgtca cttttcagtc ctcctcggga tcgcgcatca cctgcacttt 300 ctggtctcct cctgctcttt ctctcctcgc gtctcctccg cttcctctca cttttcggac 360 aaaccagtcc ttctgaggcc catgggttcc cgggctgcct ccggggctgc tcctgtgaat 420 ggcattcgag tgcccttcca gcgcggccac tgaagcagcc acaacccccg gtgctcgggg 480 cggctctcag gtccctgaag tcctgtcctc tcccggagcc gacgtgttct cagctcctgg 540 gccgcagctc ctggagtagg ggccctcctt tctcgggacc cggagctggt gcttcctgct 600 gctgtgggga ctgtgggggg tcctgactct caagctgagg ggttggagtc tgcaggctcc 660 gggcagagga ttcttcctgc gacttctctc atccccagct cattctcccc tcgcctctgg 720 ctccgagggt cctctcctct ctctcatccc acccctacta atgaccagtg atctaaggac 780 accagattcc ctctcacctc ctccctgccc atctcagggc ccgctgagtc cttttgccct 840 cccagctccc tgctacccct tcctgtgtgc tgttctctga tccatttcta gggtgtcctc 900 tgccctcatc ccctgtcccc gccaccgaag gtccctcctg caccccttat gggcctttcc 960 tacaagcagc cttcacccag tgctgcccct atgcctcccc gttcccaaat gtccctgact 1020 ctaactttct ggtgctgcct tttatccggg ggggtcttcc ctccatccca ctcccctcca 1080 gacccccaag gggaaccctg atgctaatgg cagttgggcc ttaggcaggg cgcagggcag 1140 cgcagatgcc ccctcccctc cagtgcagat gcctgctctg gaccctgcct cattgtggcc 1200 ccttccccac tccttcatcc tcagcctcac cctcttgagg accccaccct ccagcccaca 1260 ggtgctggac catccctccc tggtccctcc gcccctctcc accttgggac cttgtgctgc 1320 tcctatctct tgcccagctg ccttgggccc tcagcacgtt ctcatctttc agtgggaaag 1380 tgggagtgct ggagcatatg acagtgctga gcatctttcc caagccccac cctcccccag 1440 agcaccctcc cctcctgtcc tcaccctacc ccaagttctc ccacagtcac tcctgcccca 1500 tgctcatgcc gccctccagt tcttgctctg cccatctccc ctccccaacc cagacctaaa 1560 acaggctgtt gggccaactg ttccttgacc ttccttcttt tcttttggtt ccttgacccc 1620 agtgggctct cactccccac accgcatatc taaaatctgt tttgcctgct cttggggtgc 1680 cactgctccc cctccagcat tactcctttt ggcaggtcct tcctcaggct gagaatctcc 1740 ccctctacct tggttttctc tctctggcca gcacccccac cccttgcttt gtttttaatt 1800 tttaactttt gtttgggtac gtagtagata tatatgtata tatttatggg gtacatggga 1860 tattttcaca caggcctaca atatgtaata atcacatcag ggtaaatggg ttatatcaca 1920 acaagcattt atcctttctt tgtgctacaa acaatcccat tatgctcttt cagttatttt 1980 taaatgtaca ataaattatt gttgactgta ctcaccctgc tgtgctatct actagatctt 2040 attcattcta attatatttt tgtacccatt attaaccatc cctgctcccc cactccccac 2100 tacccttctc agcctctggt aatcatcatt ctattgtctc tccccatgag gtccattgtt 2160 ttaaattttg gctgccacaa ataagtgaga acatgcaaag tttgtctgtc tgggcctggg 2220 gcttatttca cttcacagga tgacctccag ttctttgcaa atgacacgat ggctgaatag 2280 ttctccacat acacatgtac accacatttt ctttatccat gcgtgtgttg atggacactt 2340 agattgcttg cagatcttgg ctactttgaa tagtgctgca ataaacatgg aaaagtagat 2400 agctctttaa tataccgatt tcctttcttt ggagtatatg cctaacagtg ggagtgctgg 2460 agcatatgac agctctattg tatttttagt ttttggaaga acctccacat tgtttcccat 2520 agtggttgta ctagtttacg ttcccaccaa cagtgtacat cctcaccagc attccttatt 2580 tctacatcct cgccagcatt ccttattgcc tgtcttctgg ataaaagcca gtttatctgg 2640 ggtgggatgt tatctcgtag gagttttgat ttgccttcat ctgttgacga atgatgttga 2700 gcaccttttc atatacctgt ttgccattta tatgtcttct tttgagaaat gactattcag 2760 atcttttctc atttttaaat tggattatta tatttttttt tcctatagtt gttcgagctc 2820 cttatatgtt tcagttactg atcctttgtc agatgaatag tttgaaaata ttttctccca 2880 ttcttggatg gtctcttcat tttgtttatt gtttcctttg ctgtgcagaa gcctttttac 2940 ttgatatgat cccatttatg caattttact ttggttacct gtgcttgtgg ggtattactt 3000 taaaaatctt tgcccagtcc aatatcctag agagtttccc caatgttttc ttgtatagtt 3060 tcatagtttg aggtcataga tttacatctt taatccactt tgatttgatt tttgtatatg 3120 gtgaaagaca gggtctagtt tcattcttct gcataaggat atctagtttc cccagcacca 3180 tttttgaaga gactctcctt tgccaatgtg tgttcttggt acctttgttg gaaatgagtt 3240 tactgtagat gtatggaatt gtttctgggt tctctattct gtttcattgg tctgtgtgtc 3300 tgtttttatg ccagtatcat gctgttttgg ttactgtagc tctgtagtat aatttgaagt 3360 cagataatgt gattcctcta gttttgttca ttttgctcag gatagcttta tctattctgg 3420 tttttttgtg gttccatatg cattttagga ttatttttat tatttctgtg aagaatgtca 3480 ttagtgtttt gatagggatt gcattgaatc tgtagattac tttgggtagt atggatattt 3540 caacaaaact gattcttcca atccatgaac gtggactatc ttttccattt tttgtgtcct 3600 tcaatttttt gcatcagtgt tttttgtttt tggtttttga gatggagttt cactcttgtt 3660 gcccaggcta gaatgcaagg gtgtgatctt ggctcaccgc aacctccgcc tcccaggttc 3720 aagcgattct tctgcctcag cctcccaagt agctgggatt acaggcatgt gccactgtgc 3780 ctggctaatt ttctattttt attagagatg gggtttctct atgttggcca ggctagtctt 3840 gaactcctga cctcaggtga tccacctgcc tcggcctccc aaagtgctgg gattacaggc 3900 atgagccacc acgcccagcc acatcactgt tttatagttt ttattggaga ggtctttcac 3960 ttcttcagtt aggtttattc ctcagtattt tattttattt gtagctattg taaatgggat 4020 tcgtttcttg atttcttttt cagattattt gctgttagca ctgatttttg catgttgatt 4080 ttgtatcctg caactttact gaatttgttc ttcagttcta atggtttttt ggtggagtct 4140 ttaggttttt ccaaatatca gaccacatga tctgcaaaca aggataattt gacttcttct 4200 tttccagttt taatgccctt tctttctttc tcctgtctga ttgctctagt taggatctgc 4260 agtactgtgt tgcataactg tggtaaaatt agtcatcctt gtcttattcc agatcttaga 4320 gaaaaggctt tcagttttcc cccattcagt atgttactag ctgtgagttt gtcatatatg 4380 gcttttatta tattgaggtc tgttccttgt atacttagtt ttttgagagt ttttatcatg 4440 aagggatgtt gaatttatca aatgcttttt cagtatcaat tgaatgatac tggcttttgt 4500 cctttattct gttgatatga cgtattacat tgattgattt gtgtatgtta aatcatcctt 4560 gcatacctgg aatacattcc acttgctcat aaagaatgat cttttttaat gtattgttga 4620 atgtggtttg ctagtatttc cttgacgatt tttgcatcgg tgttcatcag ggatataggc 4680 ctgtagtttt cttttttatg atgtgtcttt gcctggtttt tgtatcagga tattcctggc 4740 tttgtaaaat gagtttggaa gtattccctc ctcctctatt tttcagaaca gtttgaatag 4800 gactgacata tgttgttctt taaaagttta attgtggtaa attatacatt acataaattt 4860 tactgtttta accactttta agtgtatact cggtggcatt agatacattc acatttttgt 4920 gcaacccaaa actctgtgcc cattaatcgg taactcccca ttcctcccta cctctggccc 4980 ctggtaacca ccattctact ttttgtttct atgaatttga ccactctagg tacctcattt 5040 aagcagaatc atgtaatgtt tgtctttttg tttctggctt atttcactta taatattttt 5100 gaggttcggt gggcacagtg gctcacgcct ggatttccag cactttggga ggctgaagca 5160 ggtggatcac ctgagtttcg gagttcgaaa ccagcctggc caacatggtg aaaccccatc 5220 tctactaaaa ataataaaag ttagccgggc gtgatggcgg gtgcctgtaa tcccaactac 5280 ttgggaggct gaggcaggag aatcgcttga atccgggaag tggaggttgc agtgagctga 5340 gatcaggcca ctgcactcca gcctgggcaa caagagtgaa attccatctc caaaaaaaaa 5400 ataaaacaat aataataata ataatatttt tgaggttcat ccaagttgta gtatgggtca 5460 gaatttcatt ccttttaagg atggataata ctcattatat gtatgtacca catcttggtt 5520 atccatccct cagacaacgg acacttgggt tacttctacc ttttggatat tggcaaatat 5580 ttcatttcct ttgggtatat atttatttcc tttgggtatt tcttttgggt atatatccag 5640 aaatagaagc agtacatagg ggcttcattt tctctgtctc tttgccaacc ttgctctgtg 5700 tgtgtgtgtg tatgtgtgtg tgtaggtgtg tgataacagc catcctgatt ggtttcaggt 5760 ggcatctcat tgtggtttgg atttgcattt tcctaatgag tgctgatatt gagcatcttt 5820 tcatgtgttt gttgatcatt tgtaattttc tttgaagaat tggccattta agtcttttgc 5880 ccattttttc ccccacatag cttctcttat cagatatatg acttgcaata tttatttcat 5940 ttcggggttg attgcttttt cactctgatt gtgccctttg atgcatagat gttttgaatt 6000 ttcatcagtc tactttgtca gttctttcta ttctatctgt gctttggtgt catatccatg 6060 aaagcactgt caaatcctat gtcatgaaca ttatccccaa tgtttgcttc taagaaattt 6120 ttaggtttta gttcttgagt gtagagttta ggtctttgat tcattttgag ttaatttttg 6180 tatatagtgc aaattaaggg tccaatttta ttttaacacc ccctgccccc agaactattt 6240 gctgaaaaga tcaactgact ctttgtcacc tgctcacccc agtggacact agctgttcca 6300 tccaattgct gtcctggggc cttgtcatgc cactcttcca ctttgaaccc aagcccacac 6360 cgttgctccc ctctgggata ctgaccccac tataaacttc actggggcta caaccttcct 6420 accctttgtg cctcatgacc accccctccc ttgtccccac catgcccatg atgagtctct 6480 tctcgaggca gctccccttg cctccatctc accctcacct atgcaccaca gccacactgg 6540 acatgggtcc ctctgagcct gagtcccttc ccattcccac catcccctct ggcaagacct 6600 tccttccacc accttcatgc tcctcccttg cccctgcagg gcagcctctc cccttggccc 6660 ctattccctt agggggcttg tggccaccca gtccttgcac ctggcctaca agtttgccat 6720 cttcattccc ccttcttctg ttcatcagcc ccctcctcta tcctcccacc ctcacagttt 6780 tctttgtata tgaaatcctc gttcttgtcc ctttgcccgt gtgcatttcc tgcctcctca 6840 ggaaggttgg gacagcagac ctgtgtgtta aacatcaatg tgaagttact tccaggaaga 6900 agtttcacct gtgatttcct cttccccaga gccccacagt cttcgttata acctcacggt 6960 gctgtccggg gatggatctg tgcagtcagg gtttctcgct gaggtacatc tggatggtca 7020 gcccttcctg cgctgtgaca ggcagaaatg cagggcaaag ccccagggac agtgggcaga 7080 agatgtcctg ggaaataaga catgggacag agagaccagg gacttgacag ggaacggaaa 7140 ggacctcagg atgaccctgg ctcatatcaa ggaccagaaa gaaggtgaga gtcggcaggg 7200 gcaagagtga ctggagaggc cttttccaga aaagttaggg gcagagagca gggacctgta 7260 tctacccact ggatctggct caggctgggg gtgaggaatg ggggtcagtg gaactcagca 7320 gggaggtgag ccggcactca gcccacacag ggaggcatgg aggagggcca gggaggcgta 7380 ccccctgggc tgagttcctc acttgggtgg aaaggtgatg ggttcgggaa tggagaagtc 7440 actgctgggt gggggcaggc ttgcattccc tccaggagat tagggtctgt gagatccatg 7500 aagacaacag caccaggagc tcccagcatt tctactacga tggggagctc ttcctctccc 7560 aaaacctgga gactgaggaa tggacaatgc cccagtcctc cagagctcag accttggcca 7620 tgaacgtcag gaatttcttg aaggaagatg ccatgaagac caagacacac tatcacgcta 7680 tgcatgcaga ctgcctgcag gaactacggc gatatctaaa atccggcgta gtcctgagga 7740 gaacaggtac cgacgctggc caggggctct cctctccctc caattctgct agagttgcct 7800 cacctcccag atgtgtccag ggaaaccctc cctgtgctat ggatgaaggc atttcctgtt 7860 ggcacatcgt gtcctgattt tcctctattg ttagagccac tggataaaga cagtgggtca 7920 gggactggac catccagtgt tgtaatcagg gcaagtagag gaccctccga cagaatcctg 7980 agcctggggt gggtgtcagg caggagagga aggcttgagg gccagggctg ccccctctgc 8040 ctcccagcct gcccatcctg gagagttccc tcctggcccc acaacccagg agtccacccc 8100 tgacatcccc ctcctcagca tcaatgtggg gatcccagag cctgaggcca cagtcccatg 8160 gcccatcctc ctgccagcct ggaagaactg ggccccagag tgaggacaga cttgcaggtc 8220 aggggtccca gagggcttca gccagagtga gaacagtgaa gagaaacagc cctgttcctc 8280 tcccctcctt agaggggagc agggcttcac tggctctgcc ctttcttctc cagtgccccc 8340 catggtgaat gtcacccgca gcgaggcctc agagggcaac attaccgtga catgcagggc 8400 ttctggcttc tatccctgga atatcacact gagctggcgt caggatgggg tatctttgag 8460 ccacgacacc cagcagtggg gggatgtcct gcctgatggg aatggaacct accagacctg 8520 ggtggccacc aggatttgcc aaggagagga gcagaggttc acctgctaca tggaacacag 8580 cgggaatcac agcactcacc ctgtgccctc tggtgagcct agggtgaccc tggagagggt 8640 caggccaggg tagggacagc agggttggct gtggctctct gcccagtgta taacaagtcc 8700 cttttttttc agggaaagtg ctggtgcttc agagtcattg gcagacattc catgtttctg 8760 ctgttgctgc tgctgctatt tttgttatta ttattttcta cgtctgttgt tgtaagaaga 8820 aaacatcagc tgcagagggt ccaggtgaga aaagcgggca gtttctggag atggtaaggc 8880 ccctgtctgg gcagtagggt cccctcattg ctcctgcaaa gataggcatg ttggtgacaa 8940 ggcttctgta acaggggatg aaagttgggg aatttgggaa gggaatgggg gcaacatctc 9000 catctacacc cataagtgct gcccaagcga gggtcaaacg cccagctgtg gcatcttcct 9060 gctgcaggtg aggagtgggc agcagggagg gctgcggcgc ctgctctgtc cccatcccgg 9120 tctctgtgtc tcttggactc actagggcgc atccaggtgg ggtgagctgg gaatcacgtg 9180 ctgaatgctg aggacctgga tgatcacggc ctcagaggga gcaaatagta aaggcagctg 9240 tgatctgggg agggccagaa actggagagg aatctgagga gaggcggtgc ccctattccc 9300 ttcctctctg catccctctc ccctatttct ccagccattg gggcggacac caagaaaaag 9360 acctatgagg cccagcctgg gggccctgcc tgtgtagccc tttggagacc ccttgtaaca 9420 gggagggtcc tgagcacaca tggccatctc tgtccacttt tcagctcccc atgcacctcc 9480 tccaggagct ttcttggggt tgtcgtgtcc tctgcaccat tcgaggccct actctttcca 9540 ggttcccaca gcctggtctc cctgagtttc ttgcagatga gatggatgag tagataagca 9600 gatgtccctg ggccatttga ggagtggggc ccagcccctc atcagggcag ctgtggtccc 9660 tgttttcatc ctacctccga gtgttttctt ctccagtccc tgagggacac agtcctcagg 9720 gcccatgttt ttggggcttt aatctgtgct ctgtggcctc accttgccct ccctgagcca 9780 atttcccttt ctaaaggtgg tcactgcctg gtaagtttgg agtaagggac ggtcagaatc 9840 atttccccta cagtcaggtt gtttgatggg ggatgaaaag agacagcagg aagttttgtg 9900 tttctgcaaa gacagaagca gttcagggga cagtaagagg ctggggtgtc caggagggtg 9960 tgtctggcag tagggtcgct ggtttctcat ccttgaacct aattgcactg tcagtcggcc 10020 cctcaggcct gagcagatgg gaaggtttgt cccctgccct gcagtaagag ggccctgtcc 10080 aggaggcacc cataacaggg gcagtgcagg tctgtggtcg ctcctgctct cacctgtggc 10140 gtctcccgta gagggattat cagttctggt tccctgtggg caggaatggt ttcctcatag 10200 gtcactggag ttttggccag gaaaagagta tgaagttcat gtgccagttt ctcaaaattc 10260 ctgctttcaa tgttgatgtc aagcaaagat attcgtaatt tcagctctat aatcttaata 10320 ggatttcccc taatattgta aagcatctta tatgaaacag gaacacaaat ttctcaaaat 10380 tcctgcgatg tccaataaag attttcataa tttcggctct ccaatcttaa taggatttcc 10440 taatactgta aagcatatta aatgaaacag gaacccaaat ttggagcccc ctctccagga 10500 ggttctgtgt ggagatggtg gctgtggcag tggcagttcc caggtgcaga gggtgggcag 10560 aggcagcctc aggctaaggg gtctccccta ctccacatgg agaaaatccc ttgtaggttg 10620 caagggcagt ggccgggtgg aatccctgct agggacagag caggaaggcc tcgcagcctc 10680 accaagcagc agccctgggg tggagctgcg tttccagggt taagcggacc aggcaggagc 10740 agtggttact caacagcagg tcacaggctt gggttgtgag ggtcaggaga ggccaggcct 10800 cctcgagcaa ggtgggggtc ccagggtcag gtcaggtgca gatcctgtgg cagccacgtc 10860 tttccatgct gggcctgctg ggccccccag gctttctgat ggggtcccca gttaggagct 10920 gcctgctcag ggctgggagg ggaggagcgc tgagctgcag atagagggca gagcccacag 10980 tgggcagggc ctgccctggt gtgtaggtgc ctctgcagga gaggagggcc tggggactga 11040 gagcaagggt cagggcctct ctttgaggag gcctctcact gtaacaggac tggtcaggcc 11100 tgagaggagg tcactgggtt ccctcttggg tcttgtcctt tagtcttggg gccctttccc 11160 tccctgcacg atgagtggtg ggcacagggc aggggctgat gttgatggag tgatgggagg 11220 gaactggtag gggctgggaa aagcaaggag ggaggaagaa aaaagtgggg gcctcatctt 11280 ctctcagaga aagggcgaat ctggttttgg agcaactgaa gagagaaaag tccccaggga 11340 ataaacacaa cactgcaccc agtggagcat ttacccgttt ccctcttttc tccagagctc 11400 gtgagcctgc aggtcctgga tcaacaccca gttgggacga gtgaccacag ggatgccaca 11460 cagctcggat ttcagcctct gatgtcagat cttgggtcca ctggctccac tgagggcgcc 11520 tagactctac agccaggcag c 11541 //