Dbfetch
ID OX175575; SV 1; linear; genomic DNA; STD; HUM; 11537 BP. XX AC OX175575; XX PR Project:PRJEB53990; XX DT 07-JUL-2022 (Rel. 144, Created) DT 14-APR-2023 (Rel. 144, Last updated, Version 3) XX DE Homo sapiens, MICA gene for MHC Class I chain-related gene, cell line DE DKMS-LSL_ID20709408_MICA_1, allele MICA*010:new XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Albrecht V., Schmidt H. A., Klussmeier A., Lange V., Putke K.; RT ; RL Submitted (05-JUL-2022) to the INSDC. RL DKMS LIFE SCIENCE LAB, Research & Development, St. Petersburger Str. 2, RL Saxony, 01069 Dresden, Germany XX DR MD5; 0815bc02c177bb5176eb7d62a381a8c9. XX FH Key Location/Qualifiers FH FT source 1..11537 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /cell_line="DKMS-LSL_ID20709408_MICA_1" FT /db_xref="taxon:9606" FT exon 1..86 FT /gene="MICA" FT /allele="MICA*010:new" FT /number=1 FT CDS join(17..86,6924..7178,7453..7740,8328..8606,8706..8840, FT 11392..11519) FT /codon_start=1 FT /transl_table=1 FT /gene="MICA" FT /allele="MICA*010:new" FT /product="MHC Class I chain-related gene" FT /function="antigen presenting molecule" FT /protein_id="CAH8699395.1" FT /translation="MGLGPVFLLLAGIFPFAPPGAAAEPHSLPYNLTVLSWDGSVQSGF FT LAEVHLDGQPFLRYDRQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIK FT DQKEGLHSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQNLETEEWTVPQSSRAQTLAM FT NVRNFLKEDAMKTKTHYHAMHADCLQELRRYLESSVVLRRTVPPMVNVTRSEASEGNIT FT VTCRASSFYPRNIILTWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICRGEEQRFT FT CYMEHSGNHSTHPVPSGKVLVLQSHWQTFHVSAVAAAAAIFVIIIFYVRCCKKKTSAAE FT GPELVSLQVLDQHPVGTSDHRDATQLGFQPLMSALGSTGSTEGA" FT intron 87..6923 FT /gene="MICA" FT /allele="MICA*010:new" FT /number=1 FT exon 6924..7178 FT /gene="MICA" FT /allele="MICA*010:new" FT /number=2 FT intron 7179..7452 FT /gene="MICA" FT /allele="MICA*010:new" FT /number=2 FT exon 7453..7740 FT /gene="MICA" FT /allele="MICA*010:new" FT /number=3 FT intron 7741..8327 FT /gene="MICA" FT /allele="MICA*010:new" FT /number=3 FT exon 8328..8606 FT /gene="MICA" FT /allele="MICA*010:new" FT /number=4 FT intron 8607..8705 FT /gene="MICA" FT /allele="MICA*010:new" FT /number=4 FT exon 8706..8840 FT /gene="MICA" FT /allele="MICA*010:new" FT /number=5 FT intron 8841..11391 FT /gene="MICA" FT /allele="MICA*010:new" FT /number=5 FT exon 11392..11537 FT /gene="MICA" FT /allele="MICA*010:new" FT /number=6 XX SQ Sequence 11537 BP; 2368 A; 2965 C; 2777 G; 3427 T; 0 other; tggcgacgtc ggggccatgg ggctgggccc ggtcttcctg cttctggctg gcatcttccc 60 ttttgcacct ccgggagctg ctgctggtga gtggcgttcc tggcggtcct cggcggagcg 120 ggagcagtgg gacgtttccg ggggtcgggt gggtagcggc gagcgctgtg cggtcagggc 180 ggggctcctg tgccctgtcg gtggcgcagg gagctggacg cggcccgtta ccgccacact 240 tcagccctgc ttccccgtca cttttcagtc ctcctcggga tcgcgcatca cctgcacttt 300 ctggtctcct cctgctcttt ctctcctcgc gtctcctccg cttcctctca cttttcggac 360 aaaccagtcc ttctgaggcc catgggttcc cgggctgcct ccggggctgc tcctgtgaat 420 ggcattcgag tgcccttcca gcgcggccac tgaagcagcc acaacccccg gtgctcgggg 480 cggctctcag gtccctgaag tcctgtcctc tcccggagcc gacgtgttct cagctcctgg 540 gccgcagctc ctggagtagg ggccctcctt tctcgggacc cggagctggt gcttcctgct 600 gctgtgggga ctgtgggggg tcctgactct caagctgagg ggttggagtc tgcaggctcc 660 gggcagagga ttcttcctgc gacttctctc atccccagct cattctcccc tcgcctctgg 720 ctccgagggt cctctcctct ctctcatccc acccctacta atgaccagtg atctaaggac 780 accagattcc ctctcacctc ctccctgccc atctcagggc ccgctgagtc cttttgccct 840 cccagctccc tgctacccct tcctgtgtgc tgttctctga tccatttcta gggtgtcctc 900 tgccctcatc ccctgtcccc gccaccgaag gtccctcctg caccccttat gggcctttcc 960 tacaagcagc cttcacccag tgctgcccct atgcctcccc gttcccaaat gtccctgact 1020 ctaactttct ggtgctgcct tttatccggg ggggtcttcc ctccatccca ctcccctcca 1080 gacccccaag gggaaccctg atgctaatgg cagttgggcc ttaggcaggg cgcagggcag 1140 cgcagatgcc ccctcccctc cagtgcagat gcctgttctg gaccctgcct cattgtggcc 1200 ccttccccac tccttcatcc tcagcctcac cctcttgagg accccaccct ccagcccaca 1260 ggtgctggac catccctccc tggtccctcc gcccctctcc accttgggac cttgtgctgc 1320 tcctatctct tgcccagctg ccttgggccc tcagcacgtt ctcatctttc agtgggaaag 1380 tgggagtgct ggagcatatg acagtgctga gcatctttcc caagccccac cctcccccag 1440 agcaccctcc cctcctgtcc tcaccctacc ccaagttctc ccacagtcac tcctgcccca 1500 tgctcatgcc gccctccagt tcttgctctg cccatctccc ctccccaacc cagacctaaa 1560 acaggctgtt gggccaactg ttccttgacc ttccttcttt tcttttggtt ccttgacccc 1620 agtgggctct cactccccac accgcatatc taaaatctgt tttgcctgct cttggggtgc 1680 cactgctccc cctccagcat tactcctttt ggcaggtcct tcctcaggct gagaatctcc 1740 ccctctacct tggttttctc tctctggcca gcacccccac tccttgcttt gtttttaatt 1800 tttaactttt gtttgggtac gtagtagata tatatgtata tatttatggg gtacatggga 1860 tattttgaca caggcctaca atatgtaata atcacatcag ggtaaatggg ttatatcaca 1920 acaagcattt atcctttctt tgtgctacaa acaatcccat tatgctcttt cagttatttt 1980 taaatgtaca ataaattatt gttgactgta ctcaccctgc tgtgctatct actagatctt 2040 attcattcta attatatttt tgtacccatt attaaccatc cctgctcccc cactccccac 2100 tacccttctc agcctctggt aatcatcatt ctattgtctc tccccatgag gtccattgtt 2160 ttaaattttg gctgccacaa ataagtgaga acatgcaaag tttgtctgtc tgggcctggg 2220 gcttatttca cttcacagga tgacctccag ttctttgcaa atgacacgat ggctgaatag 2280 ttctccacat acacatgtac accacatttt ctttatccat gcgtctgttg atggacactt 2340 agattgcttg cagatcttgg ctactttgaa tagtgctgca ataaacatgg aaaagtagat 2400 agctctttaa tataccgatt tcctttcttt ggagtatatg cctaacagtg ggagtgctgg 2460 agcatatgac agctctattg tatttttagt ttttggaaga acctccacat tgtttcccat 2520 agtggttgta ctagtttacg ttcccaccaa cagtgtacat cctcaccagc attccttatt 2580 tctacatcct cgccagcatt ccttattgcc tgtcttctgg ataaaagcca gtttatctgg 2640 ggtgggatgt tatctcgtag gagttttgat ttgccttcat ctgttgacga atgatgttga 2700 gcaccttttc atatacctgt ttgccattta tatgtcttct tttgagaaat gactattcag 2760 atcttttctc atttttaaat tggattatta tatttttttt cctatagttg ttcgagctcc 2820 ttatatgttt cagttactga tcctttgtca gatgaatagt ttgaaaatat tttctcccat 2880 tcttggatgg tctcttcatt ttgtttattg tttcctttgc tgtgcagaag cctttttact 2940 tgatatgatc ccatttatgc aattttactt tggttacctg tgcttgtggg gtattacttt 3000 aaaaatcttt gcccagtcca atatcctaga gagtttcccc aatgttttct tgtatagttt 3060 catagtttga ggtcatagat ttacatcttt aatccacttt gatttgattt ttgtatatgg 3120 tgaaagacag ggtctagttt cattcttctg cataaggata tctagtttcc ccagcaccat 3180 ttttggagag actctccttt gccaatgtgt gttcttggta cctttgttgg aaatgagttt 3240 actgtagatg tatggaattg tttctgggtt ctctattctg tttcattggt ctgtgtgtct 3300 gtttttatgc cagtatcatg ctgttttggt tactgtagct ctgtagtata atttgaagtc 3360 agataatgtg attcctctag ttttgttcat tttgctcagg atagctttat ctattctggt 3420 ttttttgtgg ttccatatgc attttaggat tatttttatt atttctgtga agaatgtcat 3480 tagtgttttg atagggattg cattgaatct gtagattact ttgggtagta tggatatttc 3540 aacaaaactg attcttccaa tccatgaacg tggactatct tttccatttt ttgtgtcctt 3600 caattttttg catcagtgtt ttttgttttt ggtttttgag atggagtttc actcttgttg 3660 cccaggctag aatgcaaggg tgtgatcttg gctcaccgca acctccgcct cccaggttca 3720 agctattctt ctgcctcagc ctcccaagta gctgggatta caggcatgtg ccactgtgcc 3780 tggctaattt tctattttta ttagagatgg ggtttctcta tgttggccag gctagtcttg 3840 aactcctgac ctcaggtgat ccacctgcct cggcctccca aagtgctggg attacaggca 3900 tgagccacca cgcccagcca catcactgtt ttatagtttt tattggagag gtctttcact 3960 tcttcagtta ggtttattcc tcagtatttt attttatttg tagctattgt aaatgggatt 4020 cgtttcttga tttctttttc agattatttg ctgttagcac tgatttttgc atgttgattt 4080 tgtatcctgc aactttactc aatttgttct tcagttctaa tggttttttg gtggagtctt 4140 taggtttttc caaatatcag accacatgat ctgcaaacaa ggataatttg acttcttctt 4200 ttccagtttt aatgcccttt ctttctttct cctgtctgat tgctctagtt aggatctgca 4260 gtactgtgtt gcataactgt ggtaaaatta gtcatccttg tcttattcca gatcttagag 4320 aaaaggcttt cagttttccc ccattcagta tgttactagc tgtgagtttg tcatatatgg 4380 cttttattat attgaggtct gttccttgta tacttagttt tttgagagtt tttatcatga 4440 agggatgttg aatttatcaa atgctttttc agtatcaatt gaatgatact ggcttttgtc 4500 ctttattctg ttgatatgac gtactacatt gattgatttg tgtatgttaa atcatccttg 4560 catacctgga atacattcca cttgctcata aagaatgatc ttttttaatg tattgttgaa 4620 tgtggtttgc tagtatttcc ttgacgattt ttgcatcggt gttcatcagg gatataggcc 4680 tgtagttttc ttttttatga tgtgtctttg cctggttttt gtatcaggat attcctggct 4740 ttgtaaaatg agtttggaag tattccctcc tcctctattt ttcagaacag tttgaatagg 4800 actgacatat gttgttcttt aaaagtttaa ttgtggtaaa ttatacatta cataaatttt 4860 actgttttaa ccacttttaa gtgtatactc ggtggcatta gatacattca catttttgtg 4920 caacccaaaa ctctgtgccc attaatcggt aactccccat tcctccctac ctctggcccc 4980 tggtaaccac cattctactt tttgtttcta tgaatttgac cactctaggt acctcattta 5040 agcagaatca tgtaatgttt gtctttttgt ttctggctta tttcacttat aatatttttg 5100 aggttcggtg ggcacagtgg ctcacgcctg gatttccagc actttgggag gctgaagcag 5160 gtggatcacc tgagtttcgg agttcgaaac cagcctggcc aacatggtga aaccccatct 5220 ctactaaaaa taataaaagt tagccgggcg tgatggcggg tgcctgtaat cccaactact 5280 tgggaggctg aggcaggaga atcgcttgaa tccgggaagt ggaggttgca gtgagctgag 5340 atcaggccac tgcactccag cctgggcaac aagagtgaaa ttccatctcc aaaaaaaaaa 5400 aataaaacaa taataataat aatatttttg aggttcatcc aagttgtagt atgggtcaga 5460 atttcattcc ttttaaggat ggataatact cattatatgt atgtaccaca tcttggttat 5520 ccatccctca gacaatggac acttgggtta cttctacctt ttggatattg gcaaatattt 5580 catttccttt gggtatatat ttatttcctt tgggtatttc ttttgggtat atatccagaa 5640 atagaagcag tacacagggg cttcattttc tctgtctctt tgccaacctt gctctgtgtg 5700 tgtgtgtatg tgtgtgtgta ggtgtgtgat aacagccatc ctgattggtt tcaggtggca 5760 tctcattgtg gtttggattt gcattttcct aatgagtgct gatattgagc atcttttcat 5820 gtgtttgttg atcatttgta attttctttg aagaattggc catttaagtc ttttgcccat 5880 tttttccccc acatagcttc tcttatcaga tatatgactt gcaatattta tttcatttcg 5940 gggttgattg ctttttcact ctgattgtgc cctttgatgc atagatgttt tgaattttca 6000 tcagtctact ttgtcagttc tttctattct atctgtgctt tggtgtcata tccatgaaag 6060 cactgtcaaa tcctatgtca tgaacattat ccccaatgtt tgcttctaag aaatttttag 6120 gttttagttc ttgagtgtag agtttaggtc tttgattcat tttgagttaa tttttgtata 6180 tagtgcaaat taagagtcca attttatttt aacaccccct gcccccagaa ctatttgctg 6240 aaaagatcaa ctgactcttt gtcacctgct caccccagtg gacactagct gttccatcca 6300 attgctgtcc tggggccttg tcatgccact cttccacttt gaacccaagc ccacaccgtt 6360 gctcccctct gggatactga ccccactata aacttcactg gggctacaac cttcctaccc 6420 cttgtgcctc atgaccaccc cctcccttgt ccccgccatg cccatgatga gtctcttctc 6480 gaggcagctc cccttgcctc catctcaccc tcagcctatg caccacagcc acactggaca 6540 tgggtccctc tgagcctgag tcccttccca ttcccactgt cccctctggc aagaccttcc 6600 ttccaccacc ttcatgctcc tccctcgccc ctgcagggca gcctctcccc ttggccccta 6660 ttcccttagg gggcttgtgg ccacccagtc cttgcacctg gcctacaagt ttgccatctt 6720 tattccccct tcttctgttc atcagccccc tcctctatcc tcccaccctc acagttttct 6780 ttgtatatga aatcctcgtt cttgtccctt tgcccgtgtg catttcctgc cccaggaagg 6840 ttgggacagc agacctgtgt gttaaacatc aatgtgaagt tacttccagg aagaagtttc 6900 acctgtgatt tcctcttccc cagagcccca cagtcttcct tataacctca cggtgctgtc 6960 ctgggatgga tctgtgcagt cagggtttct tgctgaggta catctggatg gtcagccctt 7020 cctgcgctat gacaggcaga aatgcagggc aaagccccag ggacagtggg cagaagatgt 7080 cctgggaaat aagacatggg acagagagac cagggacttg acagggaacg gaaaagacct 7140 caggatgacc ctggctcata tcaaggacca gaaagaaggt gagagtcggc aggggcaaga 7200 gtgactggag aggccttttc cagaaaagtt aggggcagag agcagggacc tgtctcttcc 7260 cactggatct ggctcaggct gggggtgagg aatgggggtc agtggaactc agcagggagg 7320 tgagccggca ctcagcccac acagggaggc atggaggagg gccagggagg cgtaccccct 7380 gggctgagtt cctcacttgg gtggaaaggt gatgggttcg ggaatggaga agtcactgct 7440 gggtgggggc aggcttgcat tccctccagg agattagggt ctgtgagatc catgaagaca 7500 acagcaccag gagctcccag catttctact acgatgggga gctcttcctc tcccaaaacc 7560 tggagactga ggaatggaca gtgccccagt cctccagagc tcagaccttg gccatgaacg 7620 tcaggaattt cttgaaggaa gatgccatga agaccaagac acactatcac gctatgcatg 7680 cagactgcct gcaggaacta cggcgatatc tagaatccag cgtagtcctg aggagaacag 7740 gtaccgacgc tggccagggg ctctcctctc cctccaattc tgctagagtt gcctcacctc 7800 ccagatgtgt ccagggaaac cctccctgtg ctatggatga aggcatttcc tgttggcaca 7860 tcgtgtcctg attttcctct attgttagag ccactggata aagacagtgg gtcagggact 7920 ggaccatcca gtgttgtaat cagggcaagt agaggaccct ccgacagaat cctgagcctg 7980 tggtgggtgt caggtaggag aggaagcctt cagggccagg gctgccccct ctgcctccca 8040 gcctgcccat cctggagagt tccctcctgg ccccacaacc caggagtcca cccctgacat 8100 ccccctcctc agcatcaatg tggggatccc agagcctgag gccacagtcc caaggcccat 8160 cctcctgcca gcctggaaga actgggcccc agagtgagga cagacttgca ggtcaggggt 8220 cccggagggc ttcagccaga gtgagaacag tgaagagaaa cagccctgtt cctctcccct 8280 ccttagaggg gagcagggct tcactggctc tgccctttct tctccagtgc cccccatggt 8340 gaatgtcacc cgcagcgagg cctcagaggg caacatcacc gtgacatgca gggcttccag 8400 cttctatccc cggaatatca tactgacctg gcgtcaggat ggggtatctt tgagccacga 8460 cacccagcag tggggggatg tcctgcctga tgggaatgga acctaccaga cctgggtggc 8520 caccaggatt tgccgaggag aggagcagag gttcacctgc tacatggaac acagcgggaa 8580 tcacagcact caccctgtgc cctctggtga gcctagggtg accctggaga gggtcaggcc 8640 agggtaggga cagcagggat ggctgtggct ctctgcccag tgtataacaa gtcccttttt 8700 ttcagggaaa gtgctggtgc ttcagagtca ttggcagaca ttccatgttt ctgctgttgc 8760 tgctgctgct gctatttttg ttattattat tttctatgtc cgttgttgta agaagaaaac 8820 atcagctgca gagggtccag gtgagaaaag cgggcagttt ctggagatgg taaggcccct 8880 gtctgggcag tagggtcccc tcattgctcc tgcaaagata ggcatgttgg tgacaaggct 8940 tccgtaacag gggatgaaag ttggggaatt tgggaaggga atgggggcag catctccatc 9000 tacacccata agtgctgccc aagcgagggt caaacgccca gctgtggcat cctcctgctg 9060 caggtgagga gtgggcagca gggagggctg cggcgcctgc tctgtcccca tcccggtctc 9120 tgtgtctctt ggactcacta gggcgcatcc aggtggggtg agctgggaat cacgtgctga 9180 atgctaaggg cctggatgat cacggcctca gagggagcaa atagtaaagg cagctgtgat 9240 ctggggaggg ccagaaactg gagaggaatc tgaggagagg cggtgcccct attcccttcc 9300 tctctgcatc cccctcccct gtttctccag ccatcggggc ggacaccgag aaaaagacct 9360 atgaggccca gcctgggggc cctgcctgtg tagccctttg gagacccctt gtaacaggga 9420 gggtcctgag cacacatggc catctctgtc cactttgcag ctccccatgc acctcctcca 9480 ggagctttct tggggttgtt gtgtcctctg caccattcga ggccctactc tttccaggtt 9540 cccacggcct ggcctccctg agtttcttgc agatgacatg gatgagtaga taagcagatg 9600 tccctgggcc atttgaggag tggggcccag cccctcatca gggcagctgt ggtccctgtt 9660 ttcatcctac ctccgagtgt tttcttctcc agtccctgag ggacacagtc ctcagggccc 9720 atgtttttgg ggatttaatc tgtgctctgt ggcctcacct tgccctccct gagccaattt 9780 ccctttctaa aggtggtcac tgcctggtaa gtttggagta agggacggtc agaatcattt 9840 cccctacagt caggttgttt gatgggggat gaaaagagac agcaggaagt tttgtgtttc 9900 tgcaaagaca gaagcagttc aggcgacagt aagaggctgg ggtgtccagg aggatgtgtc 9960 tggcagtagg gtcgctggtt tctcatcctt gaacctaatt gcactgtcaa tcggcccctc 10020 aggcctgagc agatgggaag gtttgtcccc tgccctgcag caagagggcc ctgtccagga 10080 ggcacccaca acaggggcag tgcaggtctg tggtcactcc tgctctcacc tgtggcgtct 10140 cccgtagagg gattgtcagt tctggttccc tgtgggcagg aatggtttcc tcataggtca 10200 ctggagtttt ggctaggaaa agagtatgaa gttcatgtgc cagtttctca aaattcctgc 10260 tttcaatgtt gatgtccagt aaagatattc gtaatttcag ctctataatc ttaataggat 10320 ttcctctaat attgtgaagc atattatatg aaacaggaac acaaatttct caaaattcct 10380 gcgatgtcca ataaagattt tcataatttc agctctgcaa tcttaatagg atttcctaat 10440 actgtaaagc atattaaatg aaacaggaac tcaaatttgg agccccctct ccaggaggtt 10500 ctgtgtggag atggtggctg tggcagtggc agttcccagg tgcagagggt gggcagaggc 10560 agcctcaggc taaggggtct cccctactcc acatggagaa aatcccttgt aggttgcaag 10620 ggcagtggcc gggtggaatc cctgctaggg acagagcagg aaggcctcgc agcctcacca 10680 agcagcagcc ctggggtgga gctgcgtttc cagggttaag cggaccaggc aggagtagcg 10740 gttactcaag agcaggtcac aggcttgggt tgtgagggtc aggagaggcc aggcctcctc 10800 gagcaaggtg ggggtcccag ggtcaggtca ggtgcagatc ctgtggcagc cacgtctttc 10860 catgctgggc ctgctgggcc ccccaggctt cctgatgggg tccccagtta ggagctgcct 10920 gctcagggct gggaggggag gagcactgag ctgcagatag agggcagagc ccacagtggg 10980 cagggcctgc cctggtgtgt aggtgcctct gcaggagagg agggcctggg gactgagagc 11040 aagggtcagg gcctctcttt ggggaggcct ctcactgtaa caggactggt caggcctgag 11100 aggagggcac tgggttccct cttgggtctt gtcctttagt cttggggccc tttccctccc 11160 tgcacgatga gtggtgggca cagggcacgg gctgatgttg atggagtgat gggagggaac 11220 tggcaggggc tgggaaaagc aaggagggag gaagaaaaaa gtgggggcct catcttctct 11280 cagagaaagg gcaaatctgg ttttggagca actgaagaga gaaaagtccc cagggaataa 11340 acacaacact gcacccagtg gagcatttac ccatttccct cttttctcca gagctcgtga 11400 gcctgcaggt cctggatcaa cacccagttg ggacgagtga ccacagggat gccacacagc 11460 tcggatttca gcctctgatg tcagctcttg ggtccactgg ctccactgag ggcgcctaga 11520 ctctacagcc aggcggc 11537 //