Dbfetch
ID OW382038; SV 1; linear; genomic DNA; STD; HUM; 11510 BP. XX AC OW382038; XX PR Project:PRJEB52053; XX DT 05-APR-2022 (Rel. 144, Created) DT 11-APR-2022 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens HLA-DPB1 gene for MHC class II antigen, allele DE HLA-DPB1*04:01:01:NEW XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Lucas J., Lucas AM J.; RT ; RL Submitted (01-APR-2022) to the INSDC. RL ANTHONY NOLAN RESEARCH INSTITUTE, 77C Fleet Road, London, NW3 2QU, United RL Kingdom XX DR MD5; 6ce58264be6ab81ee58f77b221f9de42. XX FH Key Location/Qualifiers FH FT source 1..11510 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /clone="AN300987" FT /db_xref="taxon:9606" FT CDS join(367..466,4997..5260,9259..9540,10088..10198, FT 10528..10547) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAH2468741.1" FT /translation="MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECY FT AFNGTQRFLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDR FT MCRHNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQ FT EETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSA FT RSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA" FT exon 367..466 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=1 FT intron 467..4996 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=1 FT exon 4997..5260 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=2 FT intron 5261..9258 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=2 FT exon 9259..9540 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=3 FT intron 9541..10087 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=3 FT exon 10088..10198 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=4 FT intron 10199..10527 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=4 FT exon 10528..10547 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=5 XX SQ Sequence 11510 BP; 3129 A; 2536 C; 2983 G; 2862 T; 0 other; taatccctgt agatgggcca gcagaatatt tgagatcacc ttcagagcaa agaaaacgca 60 taatctcccc aaacatcatg acttatctga ctggttaaaa tgagtatcac tgtctttcct 120 ccgtcatctt aagtgcatca caggctttat attttcagac ctttcatact aactttctgc 180 ctagtgagca atgactcata caaagctcag tgtccattgg ttcttttctc agactctgtc 240 caatcccagg gtcacagaag actacttggg ttcatggtct ctaatatttc aaacaggagc 300 tccctttagc gagtccttct tttcctgact gcagctcttt tcattttgcc atccttttcc 360 agctccatga tggttctgca ggtttctgcg gccccccgga cagtggctct gacggcgtta 420 ctgatggtgc tgctcacatc tgtggtccag ggcagggcca ctccaggtaa gagccgaact 480 gccattcttg gagggtctgg ctcagggaac aattcctagg ggacgttatc tttaagggat 540 caaattctga gacaggctgc gggggctcct gccctaaggc agtgtcctct cttcccagct 600 agagaaagag gttcatcccc tataggatag cttgctaccc tactggccta ttctctctcc 660 aaggacatgg gtacagtaaa cagagagagg tgcccagtgg tcagtgtctt tggggaaaat 720 gggaccaaga ggtcctggat aaccttggac agacaaggtt tgcagagaga gaagttggca 780 agtgcaggct cctgggcgtg ttcatgtctg catccagcct ggaggggact caggcagaga 840 gccctaagct ggagtgtcca ggctctgagg atcactgagg attcagtgct cacgaagaat 900 gcctcttatt ccccagggtg gagcaggagc ccacatccct tggacaatta aggagagaag 960 ggagggaggg ggataggttt tagcccctga aggcattctc attaaaggta cttctcccag 1020 cctccccaga acttggttag ggtactagag tgggttgcga cttgtaggaa gaatgagatg 1080 aggttgtgtg ggtgcatgac agggattgag tgtaggttat cagacagcca aggaagcagt 1140 aaccaagtga aaaatctctt cttcctgctg cctccctgtg gctggtgtaa tattatggca 1200 tctatgatcc attgtttttc tctcaggata ctctcaggat atttcttttt atatatatat 1260 atactttaag ttctagggta catgtgcaca acgtgcaggt ttgttacata tgtatacatg 1320 tgccatgttg gtgtgctgca cccattaact cgtcatttac attaggtata tttcctaatg 1380 ctatccctcc cccctccccc caccccacaa caggccccgg tgtatgatgt tccccttcct 1440 gtgtccatgt gttctcattg ttcagttccc acctatgagt gagaacatgt ggtctttggt 1500 tttttgtcct tgcaatagtt tgctgtgaat gatgatttcc agcttcctcc atgtccctac 1560 aaaggacatg aactcatcct tttttatggc tgcacagtat tccatggtgt atatgtgtgc 1620 attttcttaa tccagtctat cactgatgga cagttgggtt ggttccaagt ctttgctatt 1680 gtgaatagtg ccgcaataaa catatgtgtg catgtgtctt tatagcagca tgatttataa 1740 tcctttgggt atatatccag taatgggatg gctgggtcaa atggtatttc tagttctaga 1800 tctttgagga attgccacac tgtcttgaga taccatctca caccagttaa aatggcgatc 1860 attaaaaagt caggaaacaa caggtgctgg agaggatgtg gagaaatagg aacactttta 1920 ctctgttggt gggactgtaa actagttcaa ccattgtact ctcaggacat ttctagtcca 1980 aatttacacc aacactctga gaggaaggac tgcaaagtag gtaccttagt tttccactga 2040 cttccacttt tcctgcttac acccttcctc ctagacctct ccacacccct cctaggacac 2100 acctagaagg tactgacatc atgtcacctc ctcatctttc agggtagcaa ggttggaatc 2160 tcctgaatac agcccctcaa gccctaaaac ctcttatcta ttaccttggg ttcattgtcc 2220 aggaagggga ggagaacttg aacttgtagt cacagaaggg tgctgagaac taaccagcag 2280 gacggctcag ccctgggaac tgcagagggg tgaggctggg gagagaggag gctggagcag 2340 cactggtgac actgaacagt gtcaggagga agtgacggat gcagcgcccc catcccatag 2400 gcagagctgt catgtgggat gagggacagt gttgggagcc accaaggaaa cccagaggtg 2460 ggggagcaga gagcagaagg gggcatgtga tgctgggcag tgaaagggag gacgggcaaa 2520 ggctgggttg aggtttgtag ggggaatgag atgaggcagt ggagccatgt gacagggact 2580 gagggtagat tactggagct ccctgcgtag aatgaatgtt caatcaaaac ctgctggagg 2640 gagagctgga gccatagggg agtgggtaaa gtgggcaggg ctgattccac aattccctgc 2700 atgctccccc aactccacac acatccccaa cctcaaacag ggcacaagac caaagggctg 2760 aggagccagg ctatagctta aagaggctgg gggagaaaag cttggctgag acaacccata 2820 gggagctaga ggtttttaat atatcctatt ctgaataaga gacgaattca ttcagatcag 2880 tggtttcaaa ccgtgctctg ggcaactcaa ttgctaaggg ttccacaaac aggataaagt 2940 ttcttatata caaaaaaaaa tgaaggtttc aaattacacc ataaaacccc tcattgctta 3000 tgtctacttg gcaggtaaaa ttccatttca aaagttaaat gtacttaaaa aattacctaa 3060 gactgggtaa attaaaaaaa ttaaatgttg caaagaaaaa attcaaaatt cttattcttg 3120 aatgaaaaac gttctcttac tggtgattga ggaggagaaa caaagactaa caaatgaaaa 3180 tgggagaatc cacactcaga gtggggcaat tgaacaggca ggggcggatg gatggcagag 3240 gaggaggaat ctggactcaa ggagctgggg ggctctgggc ctggaatttt agggtctggg 3300 gcccaaggca ccaggagaag aggcaggtca ggatatctga gtcaagacct gggatcttgc 3360 cttagcaatg acactggaga ctaaaggtgg actccatggt gcccttgagc ccagccctac 3420 cccatctcca ctatcctctg ccaccagctg tgcaacttct gctaggggtg aggttaataa 3480 actggagaag ttaatttgtg gagcatgaaa cagatgagca gaacaatcac agcaccttaa 3540 tttccccagt gtgcccaaga acagagcagg cctgaagata ctcaaacaga aacaaacatg 3600 tgccgtgtca ctgataattc tgtgtagaca cacacctgcc agacactgct catggcactc 3660 cctaggaaga acagcatgtg ggaaaggctg ccaaaattgt tcatgtaaaa attacatcaa 3720 tgctgtcttc ctcggtgctg cctatgcagc tggcagccat ctcttcctcc acatcatggc 3780 ctccctcaga ctcctcatga aggataagat cctcaaaaag aggaccaaca agttcatgag 3840 gcaccaatca gactgaaatg tcaaaattaa gcataactgg cggaaaccca gaggtcttaa 3900 cagtagggtt cgtagaaggt ccaagggcca gatcttgatg cccaacattg cttatgggag 3960 caacaacaac aacaaaaaaa acatgctgcc cagtggcttc cagaagtttc tggtccacag 4020 cctcaaggag ctgaaagtgc tgctgatgtg caacaaatct tactgtgctg agatcgctca 4080 caaaatttcc tccagaactg caaagtcatc atggaaagag tcacccagcc ggccatcaga 4140 gtcaccaacc ccagtaccag ggtgcacagc taagaaaatg agtagaaagt tcatgtccac 4200 gttttgtgtg taaataaaac cataaaaact gccaaaaaaa attacatcaa tgcctctaaa 4260 cccaaaggac tctaccccca caggtccctg gttgttgtgg tgattttcat tgtgtaaaat 4320 actttccaca tcttttgaca ccaagtcttt ctgcagccat gtttgaaaat taactttcag 4380 gctacagagt ctttcttata ccaaagttga agaaagtttt aagaaatata tttctacatc 4440 tcctacatgc aaaacaacag gagcaagttg aggaattctc aagaaactgg tcgagaagag 4500 agagcgctta gctatggaaa agagaaagaa ggaagggagg gcttcctgga ggaggtggca 4560 tttgaaccag gactgacatc aggatggaaa tgtcagtcag ggagttaagt agggggagca 4620 gctccgccct ccacgtcccc agctcctccc gcccctgttt tttctcccag tgaccccacg 4680 tgaaacgtct ccgcctcctc cagccaccag cagaagggac tgccttcccc tcagtgctcg 4740 cccctcccta gtgatcactc agtgcccctg agctcattct tttcagtaaa ttctctctct 4800 gcgtggtgag aaaacaggcc tggagaggct ctgcgacccg cttaggacca cagaactcgg 4860 tactaggaaa actcctattt taaaatccag ccctgggtgg gaagatttgg gaagaatcgt 4920 taatattgag agagagaggg agaaagagga ttagatgaga gtggcgcctc cgctcatgtc 4980 cgccccctcc ccgcagagaa ttaccttttc cagggacggc aggaatgcta cgcgtttaat 5040 gggacacagc gcttcctgga gagatacatc tacaaccggg aggagttcgc gcgcttcgac 5100 agcgacgtgg gggagttccg ggcggtgacg gagctggggc ggcctgctgc ggagtactgg 5160 aacagccaga aggacatcct ggaggagaag cgggcagtgc cggacaggat gtgcagacac 5220 aactacgagc tgggcgggcc catgaccctg cagcgccgag gtgagtgagg gctttgggcc 5280 ggcggtccca gggcagcccc gcgggcccgt gcccagggcg caggagcagc cgggttggcc 5340 taagggacct tagtgccggg cggaaagggg actttgggtt ggggattcat ggggggagcc 5400 catctggagc ttgtcagggg agcgagcgcg gggacctgga ctgggctgag catggagtga 5460 ggaggacgag agcagagaga cccccgggac ttcatcaggc ctggcagctg actgcatgtg 5520 gggtgaaaaa aggaagccac aggacagcgc acaagggtat ggtgtggaga tggaggtgga 5580 gatggcacag caggccacac agagaagaaa cctacaggga ggtagctggg tttgaggtgc 5640 ttgaggggca gatgggtggt ctgatgggca ggtagacaga agggtctgca gccggggagg 5700 agactgagat acatgagacc atccagggag aggggaccca gggggaagag caaaggaccg 5760 gatcctggga actggacagt tgtgatttgg ccaagacaga aaagcctgtg aaagagacca 5820 aaaaaaccca agtgcagtgt gaggagaggc ccgcagagaa gagtcttgga agctgagggg 5880 aggtgacctc agcagcacag tggacagcgg tgccagtgac ttgggaaggt cagaaaacag 5940 aagatggaaa gtgggtttgg aaaccaggga gacctgggga gagcaggttg gccgcagcgg 6000 caggagctgg aatgggaggg ggtgcatgag gctgagtgtg gcgcatcctc ctcggggctg 6060 agatggattt tacttgtctt gggttcccca cggctgtcac agggcagtgt ctcagttcat 6120 tcgtcttttt ccttcaggaa gtctgggtgt aaagggatgg agagaggtga ggtgtgtgca 6180 gtaagaggat ttctcaagga tgggacagga aggccttgga gctttggctt cctcctgtga 6240 acttgtgggg tggggagcct ggtgcaccaa cctgagggac ttgagggagt agtatcagga 6300 tgtgggattg agccctggac cttttttcta gaaagaggaa aaaaatgaag ggaggaggag 6360 gaggaagctg gggagatcac acctttgatt ttcttgttcc tggaaagtga aaggaagttc 6420 acctgctagg agtgagaagg tggacacact gggtggggat gaggtgagtg acatgagctt 6480 aggaaagttg ctgaggtaat tggttgagag aggtgttcaa ataaaaataa cgcaattggc 6540 aaaaactgtt actaagactt tgtagaggca ccaatcagtg acatggcagc attttctttc 6600 acagtaatca actgccagat tgcagacagc cctgatgcca gcctaaggag tgtgggtttc 6660 tcctccaggc ccgcaggtcc ccaacctcac tcctctgaag actcttctgg agatcctctg 6720 tgatgcacag atctccagac tcagtgcccc cagactcaga ttccctgggt ggggaggtct 6780 ggggatctct gcttgtaatc agctccctag aggttcccat gtagccagat aagtattgtc 6840 agaacactga agatttttga aaaatgaaaa agagaaggtt ggagatgtgt cttcagaaga 6900 ctactaaggg tgctggctag aggagggacc agaggcaggg agatgaggta ggaaactgct 6960 attatttgtc agggaaattg caatcaaggc atgagttaga acagggaaaa cacagaggca 7020 agggagaggt ggaaggggga ggaaagaagt agtgacaatt ccagggtgga tgtccaccca 7080 aatctagaag taattgagca aatgttttct gggcattaga gaaggcaact agaacaaaca 7140 ggaatccttg ccttggtgaa atgtatttga actgggtcag aaatgaggcc attgggtatc 7200 aggccttaac tccagcgcac cctggaggtc actgatgtgg ctccaggctg acctgctcct 7260 gtcaaagaat attgagcaag atgcctctcg tggaatgttc tgggacctta aaacagatac 7320 ccaagtattc cccctgattt catggttccc agaagctcta tggggaagaa attgtaggta 7380 attcacaact gagatttaga cataagttga atagtgtaat ggacattgag ttaaccgagg 7440 taatgaagta gtgagacaca ggtgcccctg aaataaactc acattgaggg aagaggctga 7500 caatgtggat cagtctgaaa acaaggcaaa aatacaatag ggagtaaggg ttgtgtgtca 7560 gttcaagact gtacttttac ctggcccagc gccatgttag ggtatttgtg ttctccagga 7620 agtagaaagg aaagaactga gtgattaggg acctagaaga ctaatttgag acattcctct 7680 tgatgagctg ttctctaggg tagtcctctg aaagagctgt tctctagtgg atctccctga 7740 atgaactgtt ctctaggagc acttgaccct tttctgtgtt tgttttttgt tttgtgtttg 7800 tgtttgtttt tgagacaggt tctcactttg tctcccaggc tggagtgctg tggcaccatc 7860 atggctcact gcagcctcaa cctcctgggc tcaagtgatc ctcctgcctc agcctcccat 7920 gtagctagaa ctacagatac acgtaccacc atgtctggct aatttatttt tctttttaga 7980 gatgggttct cactatgttg cccaggccgg tctcaaaacc ctgggctcaa gtgatcctca 8040 tgcctcaacc tcccaaagtg ctaagattat aggcatgacc accatgcctg gccttttctg 8100 ctttctgagg aggaaaaagg tactggtggc agagatccaa aagaaaagtt gccagtggca 8160 gtgtggaaat tcacctgaga acaacaggac aagctggggc acaaatgcaa agatgcagag 8220 ggaggcaaca cctggtcatc tgtgagacct tcatgggacc tgaagacgca gcacagagga 8280 ggaacttgaa aaaggacggg atttctacta ctcaagcatg taggagctca ggatattctg 8340 taaatatgaa gattttgagt ttttgtaggt gaggtaaaaa aatacatagg ttttttacag 8400 aataagacat gtaaagctct cttcattttc tttgtatttt catgaagtta ttagattcac 8460 aggccaccat aatgccattg tctgtatatc ttaatttcaa gatattattt gagtaaattt 8520 tgcttccttt gtatcaagat agaactttga aaaggtaggt aatttcacag ttgatcaaat 8580 attctttgcc caaattactt ttggttaaaa tttctcctaa atgtgctaca gagtgcaaac 8640 tctgtctccc tgccattccg ctatatactt actaactatt attttattca agatcatgca 8700 tgctctactt gaaggtctat ttctatcttt tcaatgctac ccttacccac tagcctaatc 8760 acattattcc tattttcaac atctaggaat caattacata gtgaacatgc ctaagaaata 8820 ataatctggg cagatgcagt ggctcaggcc cgtaatccca gccctttgag aggccgagcg 8880 ggtggatcac ttgaggtcag gcgttggtca agtgctccta gagaaccagg ctgaccaaca 8940 tggagaaacc ttgtctctac taataataca aaaattagcc aggtgaagtg gcaggcacct 9000 ataatcccag ctattcggga ggctgaggaa ggagaattgg ttgaagcccg gaggtggagg 9060 ttgcagtgag ccaatattgt gccactgcat tccagacttg gcaacagagt gacactccat 9120 ctcaacaaaa agaaagaatg aaagaaagaa agagcgagat tatgtctcaa aaaaaaggaa 9180 ggaaggaagg aaggaaggaa ggaaggaaag aaggacaatc tcaaattcta tttcattatt 9240 tttcttccac gctcctagtc cagcctaggg tgaatgtttc cccctccaag aaggggccct 9300 tgcagcacca caacctgctt gtctgccacg tgacggattt ctacccaggc agcattcaag 9360 tccgatggtt cctgaatgga caggaggaaa cagctggggt cgtgtccacc aacctgatcc 9420 gtaatggaga ctggaccttc cagatcctgg tgatgctgga aatgaccccc cagcagggag 9480 atgtctacac ctgccaagtg gagcacacca gcctggatag tcctgtcacc gtggagtgga 9540 gtgagtctct gatgaccctc tagaccccac ctctgaagag caggggactc tctggctctg 9600 gggtccactc atcttatctt ctgcatctat accctggggc catgtccaaa ccccatcttt 9660 cttctatacc agctcctgag catagtttga agccagggaa atggagactt cctgaccttg 9720 gcttaggggt tcctgaagat tcatagttct cccccttgtc agagaatcta gggacactga 9780 ctggtctcga aaccctcaca cttaggaact gacctcacac ataggaacag ttctcttcct 9840 tcagcatttt agcctcttct caggcatttt gagaggcaac ttccagaatc agcatttgcc 9900 accttgttga ggtcacaccc ctgttccaga tatgagggtg gctctttctg aatttcctct 9960 tagcaagctt tttccactgc actgtcctca tcccgatatg ctgcatcagg ctccagaatc 10020 tcagacagga catgagtagg gatgcagctg gtggaggtga cactaaacct gggtctgtcc 10080 ttcccagagg cacagtctga ttctgcccgg agtaagacat tgacgggagc tgggggcttc 10140 gtgctggggc tcatcatctg tggagtgggc atcttcatgc acaggaggag caagaaaggt 10200 gagaaagcct gcagggtgag cgggacttac cttcccctgg catattcaca cttattccac 10260 gatgaggggt ttgacagaaa agaaatgtca gaaagctcta gaggccactg atatcagata 10320 atcggggaac aaacatgacc tatagcgaga gagggatccc aggctgggat cttaatgcag 10380 ccagatgcat gaggtcccaa gtactcaggc tcctgcggag cgtccattga gtgatgggca 10440 atggaatttg gtgggatgga aatgtttctc taattatctg aggtggtttc aatggctgat 10500 tatataacct ttcgtctttc atttcagttc aacgaggatc tgcataaaca ggtaatattc 10560 ctgctttgat ttccttgtgg ggtgggttgc aggaggatat gagtcctttc tgtgcattgt 10620 aacactgagg ctcctccagg aagggaatct caggcatgaa cccctctttc aatgtcagcc 10680 ttcaggcaag tggggaaaga gcattgcttg gctccattgc tgaaggaagc agagatcaac 10740 tctgttattt atcagcctga gacgcatcct ctcaccataa tttttctctc ctggacttac 10800 aggaaggagg ctggcaacct gggataactt gtcttttacc cccacagggt tcctgagctc 10860 actgaaaaga ctattgtgcc ttaggaaaag catttgctgt gtttcgttag catctggctc 10920 caggacagac cttcaacttc caaattggat actgctgcca agaagttgct ctgaagtcag 10980 tttctatcat tctgctcttt gattcaaagc actgtttctc tcactgggcc tccaaccatg 11040 ttcccttctt cttagcacca caaataatca aaacccaaca tgactgtttg ttttccttta 11100 aaaatatgca ccaaatcatc tctcatcact tttctctgag ggttttagta gacagtagga 11160 gttaataaag aagttcattt tggtttaaac ataggaaaga agagaaccat gaaaatgggg 11220 atatgttaac tattgtataa tggggcctgt tacacatgac actcttctga attgactgta 11280 tttcagtgag ctgcccccaa atcaagttta gtgccctcat ccatttatgt ctcagaccac 11340 tattcttaac tattcaatgg tgagcagact gcaaatctgc ctgataggac ccatattccc 11400 acagcactaa ttcaacatat accttactga gagcatgttt tatcattacc attaagaagt 11460 taaatgaaca tcagaattta aaatcataaa tataatctaa tacactttaa 11510 //