Dbfetch
ID OW246296; SV 1; linear; genomic DNA; STD; HUM; 11287 BP. XX AC OW246296; XX PR Project:PRJEB51769; XX DT 26-MAR-2022 (Rel. 144, Created) DT 02-APR-2022 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens HLA-DRB1 gene for MHC class II antigen, allele DE HLA-DRB1*15:01:01:NEW XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Lucas J., Lucas AM J.; RT ; RL Submitted (24-MAR-2022) to the INSDC. RL ANTHONY NOLAN RESEARCH INSTITUTE, 77C Fleet Road, London, NW3 2QU, United RL Kingdom XX DR MD5; 2a6f852a5c0ea676d3637e2bb9e8ed76. XX FH Key Location/Qualifiers FH FT source 1..11287 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /clone="AN300918" FT /db_xref="taxon:9606" FT CDS join(563..662,5927..6196,8465..8746,9447..9557, FT 10033..10056,11199..11212) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:01:01:NEW" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAH2247432.1" FT /translation="MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECH FT FFNGTERVRFLDRYFYNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAV FT DTYCRHNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLN FT GQEEKAGMVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSE FT SAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS" FT exon 563..662 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:01:01:NEW" FT /number=1 FT intron 663..5926 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:01:01:NEW" FT /number=1 FT exon 5927..6196 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:01:01:NEW" FT /number=2 FT intron 6197..8464 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:01:01:NEW" FT /number=2 FT exon 8465..8746 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:01:01:NEW" FT /number=3 FT intron 8747..9446 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:01:01:NEW" FT /number=3 FT exon 9447..9557 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:01:01:NEW" FT /number=4 FT intron 9558..10032 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:01:01:NEW" FT /number=4 FT exon 10033..10056 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:01:01:NEW" FT /number=5 FT intron 10057..11198 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:01:01:NEW" FT /number=5 FT exon 11199..11212 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:01:01:NEW" FT /number=6 XX SQ Sequence 11287 BP; 2979 A; 2279 C; 2707 G; 3322 T; 0 other; tgaaagatca tggtgccttc atttcaactg tgagacatga cgtaattttc ccaaatctac 60 aacattaaga tatggtgcaa taaggaccag attaaaggtc tcctgatttg cggccatgtt 120 ccctccatct cctttactcc taaacacact cacactcact cctgcaaata gttgtcttgt 180 caagtgggaa atgaatgctc ttacaaggct caaacttgtg aacacatcac tgaccagcac 240 agagctggct acaatagctc cccaattaag gtgttttaca tgcaactggt tcaaaccttc 300 caagtgctaa attaaaacaa tcctttaaag aaggaaattc tgtttcagaa gaggaccttc 360 atacagcatc tctgaccagc aactgatgat gctattgaac tcagatgctg attggttctc 420 caacacgaga ttacccaacc caggagcaag gaaatcagta acttcctccc tataacttgg 480 aatgtgggtg gaggggttca tagttctccc tgagtgagac ttgcctgctt ctctggcccc 540 tggtcctgtc ctgttctcca gcatggtgtg tctgaagctc cctggaggct cctgcatgac 600 agcgctgaca gtgacactga tggtgctgag ctccccactg gctttgtctg gggacacccg 660 acgtaagtgc acattgcggg tgctgagcta ctatggggtg gggaaaatag ggagttttgt 720 taacattgtg cccaggccat gtcccttaag aaattgtgac gttttcttca gagattgccc 780 atctttatca ttggatccca aattatttcc tccataaaag gagcttgggt acttgccctc 840 ttcatgagac ttgtgtaagg ggcctttgca caaatcattt cttttcaaat ctccaccaat 900 aaaacctttg catcacatgt cctcagggtc tttagaggat ttagaaataa ggattctaaa 960 ataaattccc catacagcac ttccctttat tatgttgact tatgtcagac aaaaggaggt 1020 tcttactgaa aattttgtgg gagtcaaggg aattcaaagg gtctctccta gacgatccag 1080 tgttaggttc cccacaggac ctttggtgtt ggccatagtc ctcatatgtg aggatggacc 1140 cagtggcctc cccattatct cctttctttt cttgctgaac tccaatgttt ataaggcctg 1200 tatccctgta gtgtatgtag gttctctgac agaagttata cttagtgctc ttcctttctt 1260 gtggggaaaa gtccctggaa ctgaagctga gattgttaat acttggagtc accttacaga 1320 tacagagcat ttatgaggta ttctttggtg cctaaagaac ttaaggcatc ctctgaaaaa 1380 ctagcccagg ttcgtgttca ttatgaatct tttttaacct ttctgtactt gtttctcttg 1440 catctcctat gtgctctaac tagacatgac agaagagatt taactaatgt ataaattata 1500 tgaaattcta ttttttaagt caaaaataat caactatcag aaatttaata atgttcaaac 1560 tatatactct gtgtggggtt accgagatga tgtgaacatt gttcacgtct catagggctg 1620 aaagtcaatg ggcaagtctt gggaactcat tgtcttactg gggtcttgtc ctaaatttcc 1680 taggttcacc catcatgccc tcagctttcc ttaactagcc atgtctgctt acctcttcct 1740 ccagtttcta tttttcccca gctatgttgt catcatttcc agaaatctct aaagcttgca 1800 cagaacctta gcactatgag attcattgaa agagactttt tttctctttt tgaggtaggg 1860 cctggctctg tcacccagtc tatagctcag tggtgtgatc gaggctcact gcaacctctg 1920 ccacttatgc tcaagtgatc ctccctcctc aggctccaga gtagctggga atacaggcag 1980 gcaaccacgc ccagctaatt tttgtaattt tggtagacat gagattttgc catgttgccc 2040 aggctggtct tgaactgctg gactcaagca atcctcctgc cttggcctcc caacatgcta 2100 ggattataga tgtgagacac tgtgcccagg caaaagagat gactcttaat aaaaaaattt 2160 cctttttctt aaatcactgt ttctttatct gtgaattctt cttccaacta gaaggaggag 2220 aaaaaagaag tttgcctgta tttatcactg ggaggagaag gggtctagtg tgacattaaa 2280 atgaaagagt gctggagctt gagccccttc ttgctttcca ggatccctac agtgatcagt 2340 tcccataccc tggtttattc atgtaaacca cacttatttt tctcagcagc tactctttac 2400 tgggctccat tctaggttca aatcattcta tttgattaag ttagagagcg tccctactct 2460 catggaagtt acacaagagt agaggagaca gacactaacc caataagcat ttaacaaaga 2520 agataatgtt agagagtcat agtgcactga agaaaagaca tcaggtttgt gaaaaagaga 2580 gacatggatt cacctacttt agttcatatg ttagggagct ccacctgaga aagtgacatt 2640 cagctgagac aacaaaataa gtagacagtc gtgaagatct aagggatgaa agttccaggg 2700 agaccgaatc gggggaaagc cctgatgtgt taaattatgt ggagggagag aaagaaagct 2760 agaggggctg atgtatagaa agcaaggaaa tggagaggca gaagatgagg gtaggacaca 2820 gagaggaatt caggagcctc atcattatag gctctgatgt ccacagtaaa aaaaaattaa 2880 attttattat ttatttattt gtttgtttat tttattttat tttgtgatgg agtctctctc 2940 tgttgcccag gctagattgc tgtggcacaa tctcggctca ctgcaacctc cgcctcctgg 3000 gttcaagcga ttctcctgcc tcagcctccc gattagctgg ggccacaggc gcatgccacc 3060 acacctggct aattttttgt atttttagta gggatagggt ttcaccgtgt tagccaggat 3120 ggtctcgatc tcctgacctc gtgatccgcc cgccttggcc tcccaaagtg ctgggattac 3180 aggcgtgagc cactgcgccc ggcctatatt caatgtttaa aactaattct agctactctg 3240 tggggattgg attgttgggg ttcactagtg gttaggaaga ctatttagga gcacagcagg 3300 gaattcttca gggaaaacag gtttgtggct tcatggagtg cattagtgat aaagatggtg 3360 aaaaagataa agtggacaga cttggcatgt atttttgctt agcttgttaa tgaattactg 3420 taaagggggt agaacaatca agcttattcc taaggatttt cttttgacaa ataaatgggt 3480 ggtagtgttg tttattgaga taggaaaaac tatgggagga aatgatttga agtgggtggt 3540 ttgaaataaa agttttgttt aaatatgaga tgattgattg acatttatgt ggagaaatcc 3600 gaaggtcaat ggcatttaag agactcatgg tgaggccagg gcttcaggta tttatgttgg 3660 cagcagcaat acgtgtagtg tgttaaattc cagggcgtgg aagaggatac atagggagat 3720 ggattgtgtg aagaaaaaag aacagggcac aggccagcaa agggggctga gaaagagccc 3780 aaggatgctg gagaaaaacc aagagaacat catgtgtgta agtccaggaa aatagattat 3840 tttcaaggag aagggagagg ccaattgtgg tgagtaccac taagaggagg ggcaagtgag 3900 aatatgatag agaagcaagt gctgggtttg gtggagtcga tatttgcagt caatggagca 3960 tccaggtagg aaactggatt ggaccatttg aagagtgagt aaaagtgagg acgaggttaa 4020 ggttgactgt tttgagtaga gagcttcagg gaaggattgt tctctgggtt cagggagcca 4080 gctgaaccta aaggaaaagg ctaaagaagc tgaagagaag gaggaggacc tgtgaaccag 4140 agatgctcag tcattattag cgaggaaata cggagagccc ctgtgtgcag tggtgactac 4200 tcatgcaaaa tgtcacacag ccaatattta acacagccag tatttcacac agccaatatt 4260 tattagtgac atagcatata ccagttatta ctctaggtca tgagaatgga gtgataaata 4320 aaatgaatcc agtcgccatc actatatgcc atgtaacatt ttgcaatgac tgtgtatcag 4380 gcctatgaat ttcagtattc aatttcaata atgatcctgt tgtatctgtg gtatttaaaa 4440 acatatacat ctctggaatc taaaattgag aggttataag taacacccag tattacaaat 4500 ttagtgctgg aaatcagatt gcagtttaaa tctgagcata tagaaagtcc gtttcttcta 4560 tgtcagcaga tgctttttgt gtgaggttta ggtatactgc attatttgac ataaaccagt 4620 gtttctgccc tatgtcttca gaatgacaat tctttatgaa actaatagaa gaacagaaga 4680 caattgcaaa atcatgatga agatactaat tgctttagaa ttaaggaata caaaaaataa 4740 tatgagctgc agttatagga tcagaaaagt taaaatggga atgtattcga gtgtttatta 4800 tgtgatcagt gctaagaagt gtcatcattt aattttacac ttaacggtaa tcctgtgagg 4860 attacgctat tattaaatgc atttgataga ttacaaaaag gcttatggtt ggtaaaaatt 4920 gacccaagta gaagagatcg tgtttttatt caggttttct gattatagag tttgagagtt 4980 tgaccatcat tagtgagtag tgactatatt gtgtctgaat tattgacaca atttctgata 5040 ttcatatgta ccaggctgtt tcttagagtg gggacagaaa tgcaagggct gctagttctg 5100 atgtatagga gaaactttca ttcattttgc atttatcatt ttaaacgttg tatatgtcta 5160 tctgggcatg tgttcaagaa cacaaggaag tattaaatca ctccttcttc tgaggtttga 5220 ctagcaagtt gggctagagt tacaaataaa atacaggttc ctagtgaaat ctgaatttca 5280 gatacacaac cataatttat tggaaatcca aatttaactg ggaatcttct attattctct 5340 gctctagaac gccacacttc tgatatttct cattgctgtc taagctcttg tgtgtttggt 5400 ttttggccat cgctttcact gctctttaag ctcccccaga ggagtggaga ggtctgtttt 5460 ccctcgtttg gattcctaga ggcagcgcag gcctggcaca aggtcatcac taaggaagtg 5520 ttcacagggt gaacgcggtg ggtgctgttg aaggtaccgg taaagcgtgt gggatgagag 5580 gagcagagag tgtctttggg gctcccagga ggaggcggcg cgggctgcgg tgctgggcgg 5640 atcctcctcc agctcctgct tggaggtctc cagaacaggc tggaggcagg gagggggtcc 5700 caaaagcctg gggatgagaa ggggttttcc cgcatggtcc cccaggcccc cgttcgcctc 5760 aggaagacgg aggatgagct cctgggctgc aggtggtggg cgttgcgggt ggggccggtt 5820 aaggttccag cgcccgcacc ccgctcaggg agccccggat ggtggcgtcg ctgtccgtgt 5880 cttctcagga ggccgccctg tgaccggatg gttcgtgtcc ccacagcacg tttcctgtgg 5940 cagcctaaga gggagtgtca tttcttcaat gggacggagc gggtgcggtt cctggacaga 6000 tacttctata accaggagga gtccgtgcgc ttcgacagcg acgtggggga gttccgggcg 6060 gtgacggagc tggggcggcc tgacgctgag tactggaaca gccagaagga catcctggag 6120 caggcgcggg ccgcggtgga cacctactgc agacacaact acggggttgt ggagagcttc 6180 acagtgcagc ggcgaggtga gcatggccgc gggcggggcc tgagtccccg tgagctggga 6240 atctgagtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgagaga gagacagaga 6300 gagacagaga gaggaagaga gagagagagc gccatctgtg agcatttaga atcctctcag 6360 tccggagcaa gcagttctga gagcacaggt gtgtgtgtaa agtgtggatt tgtctgtgtc 6420 tgtgtgtctg ttgtgggagg ggaggcagga gggggctgtt tcttatcctt ggagacctct 6480 gtggggaggt gacaagggag gtgggtgctg ggggctggag agagaggaga ccttgattat 6540 ctcggtcctt agagatgcag ggaagggaaa tgtaaggtgt gtgtggttgg ggtgaaggtt 6600 taggggagga ctgctgaggg gtaaggcagg tttgggataa tgtgaggagg ccagttccag 6660 actctccctg gcatacaccc ttcgtgtaat ctctgaatta aaagtgtgtg ctgtttgttt 6720 gtaaaagcaa tagattaatt tctagaggaa ctgagtagac ctctgaggca cctctgaagc 6780 ttctttagat ctaaatttct tcctagtttt ttgttttttt cagtgtgtat atttttacat 6840 agtagaaatg actgtgaaac taactttttg aattaaagtt ttgacacggt tactatttta 6900 ttataatgct ggtagttttc tagtagttac atattattct tttatatata atatttgtga 6960 cacaactcac ctcactttcc cgtttgttga cctttattat gacattcacc agaagttgaa 7020 attgtgtgtt tctggttaat ttttaattta tattttttat ttgtaattcc tttgaattat 7080 tttgccctat ttattggccg attataatta ttgctctaag aattccctat tgtatttggt 7140 aggtaatgga caatgatcta cggtctaata tcttgagggc ttagtatttt tctcagtgac 7200 tttctgcgtt ctttgtacta taagattatt aacactttat tgatatttga tccagcattt 7260 gctccagttt gtggtttgta tgtggatttt gaaaattctt ttccatgtta agaatttgaa 7320 catttttatt taataaaata tattgcaaca tttttattaa tgatctacaa tccatctgaa 7380 atctgccatt ttgtggcatt gttgtctcca ggtttctcct tacttctaaa aaaatagttg 7440 tatttattga gagtatgcta gtgtcgggga ttttcctggg cataagcacc ccaagtaacg 7500 agtcccagac actgccttaa tccaaatgtg attctggaaa gaaaaatcat tttacaatga 7560 taggcctaat aataattatg cttgtgttgc acgggagatg cattgatcag ctaaatgtaa 7620 atataagaac tttcaaaact taaatgacgt tccctaatcc ttctctctgc ttcaggactc 7680 atgcttttct aggaaagtaa aaatttggag aatcatttct gtctgtccca ccttcccaga 7740 ggcagaacaa tttctgttgt gttctaaggt gtgagtgcat gggagtagta ttcctaaaat 7800 tcatacttgg tttcctcatg tacccaactc tgtcccttta tctatgcata ttgctttaaa 7860 tcatattttt ctgtcaaggt gtacaaggat gataaatagg tgccaagtgg agcactcaag 7920 tgtgatgagt gccctcacag tggaatggag tgagaagctt tctgacctca taaactgaag 7980 gctatcttca gtcattgttt tatatatttt acgtgcatta atcctcatat aaccccaaga 8040 ggtaaattag tataattatc cttcattgta ggtgacaaag ttgagacaca gaagaatcaa 8100 aaaactcttc caggatcaac cagtaaaagg cagaccttgg attcgaacca ggcaacctgg 8160 ctcaaatatc agttttaatt actacactct gtactttcca agatttgtaa acagtttgac 8220 aatgcatgcc gatttaaaac tatgaagaaa caaacacaat ttttcacaac acctctcaaa 8280 tctaatgggt cctcactgtc aagattaaat tccaggctga tgacactgta aggtcacatg 8340 gccagctgtg ctataggcct ggtcaaggcc agagcctggg tttgcagaga agcagacaca 8400 cagccaaacc aggagactta ctctgtcttc ctgactcatt ccctctacgt tgtttttctc 8460 ctagtccaac ctaaggtgac tgtatatcct tcaaagaccc agcccctgca gcaccacaac 8520 ctcctggtct gctctgtgag tggtttctat ccaggcagca ttgaagtcag gtggttcctg 8580 aacggccagg aagagaaggc tgggatggtg tccacaggcc tgatccagaa tggagactgg 8640 accttccaga ccctggtgat gctggaaaca gttcctcgaa gtggagaggt ttacacctgc 8700 caagtggagc acccaagcgt gacaagccct ctcacagtgg aatggagtga gcagctttct 8760 gacttcctaa atttctcacc cactaagaag gggaccgtgc taatccctga gtgtcaggtt 8820 cctcctctcc cacatcctat tttaatttgc tccatgttct catctccatc agcacaggtc 8880 actgggggta gccctgtagg tgtttctaga aacacctgta cctcctggag aagcagtctc 8940 gcctgccagg cgggagagac tgtccctctt ttgaacctcc ccatgatttt gcaggtcagg 9000 gtcacccact ctcccaggct ccaggccctg cctctgggtc tgagactgag tttctggtgc 9060 tgttgctctg agttattttt tgtgatctgg gaagaggaga agtgtagggg cctacctgac 9120 atgaggggag tccaatctca gccctgcttt ttattagctt tgtcactcta gacaaactac 9180 ttatcctcat tgagtctcag gctttctgtg gatcagatgt tgaacttgtg ccttacatca 9240 aggctgtaat atttgaatga gtttgatgtc tgaacgtcgt aactgttcag tgtaatttga 9300 aatccttttt ttctcctgaa atggctagtt attttagttc ttgtgaggca gctttctgcc 9360 ccattttcaa agctctaaat cttagagtct caagtaaaaa ggttcaattt ggaataaaca 9420 tcactaaacc tggcttcctc tctcaggagc acggtctgaa tctgcacaga gcaagatgct 9480 gagtggagtc gggggctttg tgctgggcct gctcttcctt ggggccgggc tgttcatcta 9540 cttcaggaat cagaaaggtg aggagccttt gggagctggc tctctccata ggcttttctg 9600 gaggaggaac tatggctttg ctgaggttag ttctcagtat atgagtggcc ctgaataaag 9660 cctttctttc cccaaacggc tctaatgtcc tgctaatcca gaaatcatca gtgcatggtt 9720 actatgtgaa agcataatag cttgtggcct gcagagacga gaggaaggtt aacaagtagg 9780 ggtcctttgg tttgagatcc tggagcaaat taaggaagag ccactaaggc taatggaatt 9840 acactggatc ctgtgacaga cacttcaggc ttcatgggtc acatggtctg tttctgctcc 9900 tttctgccct ggttggtgtg ggttgtggtg ttagagaaat ctcaggtggg agatctgggg 9960 ctgggacatt gtgttggagg acagatttgc ttcaataact tttaagtgta tatcttttcc 10020 tctttttccc aggacactct ggacttcagc caacaggtaa taccttttaa tcctctttta 10080 gaaacagaca cagtttccct agtgagaggt gaagccagct ggacttctgg gtggggtggg 10140 gacttggaga acttttctta caagaggttt ttttttgttt tttttttttt tttttttttt 10200 gagacggagt ctcgctctgt cgcccaggct ggagtgcagt ggcgggatct cggctcactg 10260 caagctccgc ctcccgggtt cacgccattc tcctgcctca gcctcccaag tagctgggac 10320 tacaggcgcc cgccactacg cccggctaat tttttgtatt tttagtagag acggggtttc 10380 accgttttag ccaggatggt ctcgatctcc tgacctcgtg atccgcccgc ctcggcctcc 10440 caaagtgctg ggattacagg cgtgagccac cgcgcccggc ctacaagagg tttctaaatg 10500 caccaatcag tgctttgtaa aaacacacca ataggttctc tgtggctagc tggatgtttg 10560 taaaatggac caattcgcac tctgtaaaat agaccaatca gcactcttta aaatggacca 10620 atcagcactt ttaaaatggg ccaatcacca ctctttaaaa tggaccaatc agcactcttt 10680 aaaatggacc aatctgcagg acatgggcag ggacaaatac aggaataaaa gctggccacc 10740 ccaaccagca gtggcaaccc actcaggtcc tcttccctgc tgtggaagtt ttgttctttt 10800 gatcttcaca ataaatcttg ctgctgccca ctctttggat ccctgccgcc tttaagagct 10860 gtaacactca ctgtgaaggt ctgcaggaag tcagcgagac cacaaaccca ccggaaggaa 10920 caaactcagg acacaccaga atgatggtag aggtgataag gcatgagaca gaaataatag 10980 gaaagacttt ggatccaaat ttctgatcag gcaatttaca ccaaaattcc tcctctccac 11040 ttagaaaagg tgtgctctgc gggactattg gctcagggga gactcaggaa cttctttttc 11100 ttcttcctgc agtgctctca tctgagccct tgaaagaggg gaaaagaaac tgttagtaga 11160 gccaggttga aaacaacact ctcctctgtc ttttgcagga ttcctgagct gaaatgcaga 11220 tgaccacatt caaggaagaa ctttctgccc cggctttgca ggatgaaaag ctttcctgct 11280 tggcagt 11287 //