Dbfetch
ID ON693235; SV 1; linear; genomic DNA; STD; HUM; 6521 BP. XX AC ON693235; XX DT 04-SEP-2022 (Rel. 144, Created) DT 06-SEP-2022 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens isolate A3074D1 MHC class II antigen (HLA-DQB1) gene, DE HLA-DQB1*04var allele, complete cds. XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RC Publication Status: Available-Online prior to print RP 1-6521 RX PUBMED; 36004477. RA D'Silva S.Z., Tambe M., Pinto A., Singh M.; RT "Identification of the novel HLA-DQB1*04:02:01:18 allele in a Maharashtrian RT individual from India"; RL HLA 0:0-0(2022). XX RN [2] RP 1-6521 RA D'Silva S.Z., Tambe M., Pinto A.S., Singh M.; RT ; RL Submitted (07-JUN-2022) to the INSDC. RL Transplant Immunology & Immunogenetics Lab, ACTREC, Kharghar, Navi Mumbai, RL Maharashtra 410210, India XX DR MD5; a04e8f53f08828aedf6a8c2e7c553fde. XX CC ##Assembly-Data-START## CC Assembly Method :: NGSengine v. v2.25 CC Assembly Name :: HLA-DQB1 CC Coverage :: Full gene CC Sequencing Technology :: Illumina CC ##Assembly-Data-END## XX FH Key Location/Qualifiers FH FT source 1..6521 FT /organism="Homo sapiens" FT /isolate="A3074D1" FT /mol_type="genomic DNA" FT /country="India" FT /sex="female" FT /tissue_type="blood" FT /db_xref="taxon:9606" FT gene 1..6521 FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*04var" FT mRNA join(1..144,1599..1868,4399..4680,5196..5306,6410..6521) FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*04var" FT /product="MHC class II antigen" FT exon 1..144 FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*04var" FT /number=1 FT 5'UTR 1..35 FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*04var" FT CDS join(36..144,1599..1868,4399..4680,5196..5306,6410..6423) FT /codon_start=1 FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*04var" FT /product="MHC class II antigen" FT /protein_id="UVC66363.1" FT /translation="MSWKKALRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVFQFKG FT MCYFTNGTERVRGVTRYIYNREEYARFDSDVGVYRAVTPLGRLDAEYWNSQKDILEEDR FT ASVDTVCRHNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRW FT FRNDQEETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRA FT QSESAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKGLLH" FT intron 145..1598 FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*04var" FT /number=1 FT exon 1599..1868 FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*04var" FT /number=2 FT intron 1869..4398 FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*04var" FT /number=2 FT exon 4399..4680 FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*04var" FT /number=3 FT intron 4681..5195 FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*04var" FT /number=3 FT exon 5196..5306 FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*04var" FT /number=4 FT intron 5307..6409 FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*04var" FT /number=4 FT exon 6410..6521 FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*04var" FT /number=5 FT 3'UTR 6424..6521 FT /gene="HLA-DQB1" FT /allele="HLA-DQB1*04var" XX SQ Sequence 6521 BP; 1637 A; 1488 C; 1613 G; 1783 T; 0 other; tgttgactac cactactttt cccttcgtct caattatgtc ttggaagaag gctttgcgga 60 tccctggagg ccttcgggta gcaactgtga ccttgatgct ggcgatgctg agcaccccgg 120 tggctgaggg cagagactct cccggtaagt gcagggccac tgctctccag agccgccact 180 ctgggaacag gctctccttg ggctggggta gggggatggt gatctccatg atctcggaca 240 caatctttca tcaacatttc ctctctttgg ggaaagagaa cgatgttgca ttcccattta 300 tcttttagtg atgaggtgag cacagtcgga tccccatcct acaggcttaa gcctggaaga 360 gaaggagaga ggagaggaaa gaggagacaa agtgtacatt tactaccagt gacaggacaa 420 agtgagcatg gggttatttt tgaagatatg aatttctcca gagacacagc aggatttgtc 480 atttaggcgt gccccaagac tttgcctgga ctaaatatta tgggatcctg cattgggaaa 540 tgtaaggcag caatggtgtc tgtagtctcc gtatttgagg aaaagttgtc tgtattcctg 600 actgactgga gcgtttgtgg aggcaaaatc ttggtactga aggaagctga ctggatgacc 660 acagacaggg agtcttcagg tttcactgat ttatgggcaa atggtgactt gagtgggatt 720 cagagacccg agttggtgga ctgaatttag cagaaaggag gatgtaaaga agggaaataa 780 catatattgt gaaaccactc atttcagaca cagcacaata ctttacataa attctctctc 840 actccttcta acatcctgtg tgtagatatc atgattttct tttacacaat tatacttgtg 900 atatggatat tctgttacat acctgcccta gctggtgact gccacagctt aattggaatc 960 tagtttatca aattcaaaag cttgtgctct ttccatgaat aaatgtttct ttctaggact 1020 cggaggtgta ggtcctttct aacataaaag tgagtgaacc tcacatggca ttcggaaggg 1080 taaatccagg catgggaagg gaggtatttt accgagggac caagagaata cgcatatcag 1140 aacgaggaca ggcttaattt ctggacccgt ctcatcattc ccttgaactc ccaggtttat 1200 gtggataatt ttatctctga ggtttccagg agctcaatgg aaaatgggat ttcatgcgag 1260 agcgccctga ttccctctaa gtgcagaggt ctatgtaaaa tcagcccgac tgcctcttcc 1320 ctcggttcac aggctccggc agggacaggg ctttccgccc tttcctgcct gcaggaaggc 1380 ggattccgga agcccccaga gagggcgggc agggctgggc agggctgggc agagccgccg 1440 ggcggatcac aagtctggag cgccaggcac gggcgggcgg gaactggagg tcgcgcgggc 1500 ggttccacag ctccgggccg ggtcagggcg gcggctgcgg gggcggccgg gctggggccg 1560 ggccggggcc tgactgaccg gccggtgatt ccccgcagag gatttcgtgt tccagtttaa 1620 gggcatgtgc tacttcacca acgggaccga gcgcgtgcgg ggtgtgacca gatacatcta 1680 taaccgagag gagtacgcgc gcttcgacag cgacgtgggg gtgtatcggg cggtgacgcc 1740 gctggggcgg cttgacgccg agtactggaa tagccagaag gacatcctgg aggaggaccg 1800 ggcgtcggtg gacaccgtat gcagacacaa ctaccagttg gagctccgca cgaccttgca 1860 gcggcgaggt gagcgtcgtc gcccgtctgc gaggcccatc cttggcaggg gcccagagtc 1920 tctgcgccag gaggggcgaa gggggcgcgg cctctggaac ctgagccttg ttcgttccac 1980 cccggctgac aggaggcggc ggtgggggtg ctgggggctg gtgcatcgga ggggcaggga 2040 cctagggcag agcaggggga caggcagagt tggtcaagct gcctagtttc gccccatcct 2100 ccccgtccgt cggcctcgcc ctctgctctg cacgttcttg cctcgtgcct tatgcgtttg 2160 cctcctcgtg ccttaccttt actaagcagt tctctctgcc cccaatttcc gccctcttcc 2220 cctgcccgcc cgcccggcta gcactgccgc acccggcaag gtccacctac acagctcatg 2280 cagtgggaag cttcagactt ggcctgatgg agttagggct gccccacaac tgcgcgcagg 2340 gcatccagca attacagttg tcaaataaga tattttgatt tttgacttca aattattatt 2400 catcgtaatt ctgttttctt aaatggctct cattcatggc ggagctcttt gagatgagag 2460 tgttttaatc attgcatgcc tggtatctga cacattgact ggcatgtggt atgagctcaa 2520 tgatcttctg ttaaattaat gaataaatgt gctcagctgc caatccactt aggctcaagg 2580 gaaagcagag gataaataga gccttaaaaa tggactttta ttaattattt tctgtcattt 2640 tgcttaattc tttaaagtaa actcttattg acttgaatct taatagagtt tgtgaataca 2700 aagtctgagg aaaaaagtgt ttgctaaaaa taaaaacaac acttgaatga tgtttgtaag 2760 gcagttttaa tttcttagaa aagctgaaca aatggcacaa tgcaaagagc agaagttttg 2820 gaataagtag attgaagcaa ttaaattatt ggataaaaat agtttcaggt tgcttttggc 2880 ttaggttctc ccctcccccc atcactatcc acttcaggaa taaacattct gaaagtcaat 2940 tttacccatt tagtgagcac ttatttctag acagttacct tatcaaatac catctatgtt 3000 acgtcattta atctcacagt tgcctgtgca ttagggatta gcatcaccac tttatatatc 3060 ctaatattag tacatgataa acactttaag taatcagccc acaagtactc accaagacct 3120 taagcctccc aaagtacaca atattcttta tgttcttcac tacacatcta tagagtcaaa 3180 gggacacaaa gccttgttaa agccagtttt gactagaagc agcaatgagt ctcatcctgt 3240 ttgatctcca tgttaatggg acaaaatgat actttcaagg cattgaaaat ttatgattaa 3300 tcaatcccta gtctgactcc agtgttacct atgcagattc acaaaacttt tagtttactt 3360 tacactccct tgccttcttt tgactcacat cgtagtgcca gcaagtactt acatttttgc 3420 tattttggtt ctatttccat aaaatttatt ttatcatctt ttctcataaa tttgtgccct 3480 ctattttact cccagtctgt gtaagatgaa caaatcttat aaggccacat agctgactgt 3540 gatttcaggt ggactccagg aaggagaacc aaagaaaagt tcaagtccaa gcagaaaccg 3600 tgattccttc cggatgatgg ctcaagagtg ccttttaatt ggggtgcaac ctgctgacct 3660 cagcaaatct cagctatatt tatatgttca cattacaggc tcattaacct aggctgatct 3720 ctgcaaggat ctcagaatat tttctacaga taacatacat gataatatct gatttcagga 3780 caaaaaagta attctcaata gcaagggaat ggagtagggt agacagctag taattaaact 3840 cacttgtatg ttaaaaataa attaaggaaa aaaagaaaat gagagaacat attactaaat 3900 aaagaaagca tacattaaat atttactata gtttcacact aagagaataa aggaaatgca 3960 ataaagtggc ctgaaagata aaggatgaga tgtgtaaaga gacagggaaa gatgtgtcat 4020 ttttttacta tgagcagcag tctgagaaga taaaggaatc gagttatggg caaacatgat 4080 gtttgatcag tgctatttgt tttgaaggcc tgcctacttt tgtttcaaat attacagact 4140 tttgaaatca cattcttttt gttttttgct gtctgttact agatcgcaca ttctgtaaag 4200 gcagggacca tggtatgttg tttatctttg gattctcagt gattgtcata tttatatttg 4260 ttgaatgaat cttaatccaa gacttggact ccaggtatct ttccactctg gttccaagga 4320 gggaccattc ccaatggtag acgtgctgtg tggtctcaca tctcactcct gtcttttcct 4380 gtctgttact gccctcagtg gagcccacag tgaccatctc cccatccagg acagaggccc 4440 tcaaccacca caacctgctg gtctgctcag tgacagattt ctatccagcc cagatcaaag 4500 tccggtggtt tcggaatgac caggaggaga caactggcgt tgtgtccacc ccccttatta 4560 ggaacggtga ctggaccttc cagatcctgg tgatgctgga aatgactccc cagcgtggag 4620 acgtctacac ctgccacgtg gagcacccca gcctccagaa ccccatcatc gtggagtggc 4680 gtaaggggat attgagtttc tgttactatg ggccccacaa gacaaagggc agagctcctt 4740 ctgacccatt ccttcccatc tcttatccct gatgtcacta ctgagctggg gatcacagga 4800 gactagagca cctcttgctc catggcaagt gcatcagaag aatcctgatc tcatcacctt 4860 tccagatgct agggaaatta ttctatgtac tgtttctcca gatcccagtc ctgatagctc 4920 ggagggactg attattaggg ctggtgactg ggatcttagg gtttaaggta tggatgagtt 4980 cctgaggagt ggagatctgc ttccccgctc tctcacctac tcactgtacc gaaggaccta 5040 ttggctggct ttcccctccc ttaggggtgg tctgaatgga ggactaggtt cctttgacac 5100 tttcacctcc tgcatctcag actggacttc agctcctcag cagggatgct atggggtgta 5160 gggacaaaca ctgacactca ggctctgctt cttaggggct cagtctgaat ctgcccagag 5220 caagatgctg agtggcattg gaggcttcgt gctggggctg atcttcctcg ggctgggcct 5280 tattatccat cacaggagtc agaaaggtga ggaaccccaa gggaaaaggg gaagatgggc 5340 tgtgacccag accctctgtt cagggaggtc ctgtctctag atgtggctct ttcctcctga 5400 ccctgagagg aagaaaactg agctggaggt gggaggagac aggacaagat tggaggaggc 5460 attactagct gaaaggtagc cctgtcacac aggtgactga tagagcttat tccaggatgt 5520 acttactgtt catcgtctca ttggctcctt tccaaaagct tcctccatta agagggtcag 5580 agccttggcc tccttgcctt ctagtgacaa tttcctttgt tttaggggat tttaaattag 5640 ggtacttaag gccttgaaga acatgagtgg taagagaata taactctaat taagtcacat 5700 gtgtcatttt cctttggggt gagagagtgg ctgtttgtgt aatgagacct ttctctgcat 5760 aacttccttt tgtaagacct caagggcctc caccagcagg tgatatttca gccatgagcc 5820 agtgtggggg ggcacaggtg taagagggaa gagcatgagc tgaatgcacc tgaccacaat 5880 ggtctctgtt catggtatat ttgctgctat gaggatcaag acttagggtc gaagtttgcc 5940 agtttctagg aatctccaga ggttgttccc cagaaccaag ccttaacttt ggtggtatct 6000 tcttgtgaaa tgtgaagcca gaaccacagc ttaaatgtta gacaagagga tgatgcccac 6060 tttgtgccac atgttggtgg ctactgcctg taggcatttt ccagtgactg aaagaggctg 6120 ctagtggtag ggatgaggta tcatccaatt ttctaaaaag attgaaccct tcatattccc 6180 cagaagagta acagctgttc cgccacttcc cacatatctg catcaagctg aagttctgtg 6240 tcctcacgag ctgatttcac ctttgcacag atcttgcggg aggtgacgat aatacattct 6300 ggacctcagc tttctctgtc tgaagctgca gggggcccct gaggggtggg ggagattgca 6360 ggcccaccag cgtaccctgt gctgatcatc cctcttctct cttcttcagg gctcctgcac 6420 tgactcctga gactatttta actgggattg gttatcactt ttctgtaacg cctgcttgtc 6480 cctgcccaga attcccagct gcctgtgtca gcctgtcccc c 6521 //