Dbfetch
ID OK332109; SV 1; linear; genomic DNA; STD; HUM; 5612 BP. XX AC OK332109; XX DT 01-APR-2022 (Rel. 144, Created) DT 11-APR-2022 (Rel. 144, Last updated, Version 2) XX DE Homo sapiens MHC class II antigen (HLA-DPA1) gene, HLA-DPA1*02:34var DE allele, complete cds. XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-5612 RA Mosbruger T.L., Dinou A., Ferriola D., Duke J.L., Pagkrati I., Damianos G., RA Kotsopoulou I., Tairis N., Tishkoff S., Monos D.S.; RT ; RL Submitted (16-SEP-2021) to the INSDC. RL Pathology, The Children's Hospital of Philadelphia, 3615 Civic Center Blvd. RL Rm 707A, Philadelphia, PA 19104, USA XX DR MD5; 455e5d7aa38c4fe6402e76f29f4a51f3. XX CC ##Assembly-Data-START## CC Assembly Method :: Twin v. 3.1.3; GenDx v. 2.13 CC Assembly Name :: Novel HLA alleles CC Coverage :: 5'UTR to 3'UTR CC Sequencing Technology :: Illumina; Oxford Nanopore CC ##Assembly-Data-END## XX FH Key Location/Qualifiers FH FT source 1..5612 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT gene 1..5612 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:34var" FT mRNA join(1..166,3723..3968,4309..4590,4805..5612) FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:34var" FT /product="MHC class II antigen" FT exon 1..166 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:34var" FT /number=1 FT 5'UTR 1..66 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:34var" FT CDS join(67..166,3723..3968,4309..4590,4805..4959) FT /codon_start=1 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:34var" FT /product="MHC class II antigen" FT /protein_id="UED37008.1" FT /translation="MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQ FT THRPTGEFMFEFDEDEQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTL FT IQRSNHTQAANDPPEVTVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGV FT AESLFLPRTDYSFHKFHYLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTE FT TVLCALGLVLGLVGIIVGTVLIIKSLRSGHDPRAQGPL" FT intron 167..3722 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:34var" FT /number=1 FT exon 3723..3968 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:34var" FT /number=2 FT intron 3969..4308 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:34var" FT /number=2 FT exon 4309..4590 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:34var" FT /number=3 FT intron 4591..4804 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:34var" FT /number=3 FT exon 4805..5612 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:34var" FT /number=4 FT 3'UTR 4960..5612 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:34var" XX SQ Sequence 5612 BP; 1493 A; 1339 C; 1058 G; 1722 T; 0 other; tccactcggc ctcagttcct catcactgtt cctgtgctca cagtcatcaa ttatagaccc 60 cacaacatgc gccctgaaga cagaatgttc catatcagag ctgtgatctt gagagccctc 120 tccttggctt tcctgctgag tctccgagga gctggggcca tcaagggtga gtgctcagga 180 ggacgcaaga gcgtcggggt gagtgatggg gtggttcaca tcaattgttg cttcaggaat 240 cacagatttt aggggctcat tgatctatct ggtcctcata gtctatgttc cctctggccc 300 tcataataat aacagcaata acagccagaa tttatgagac tcctgcatag tttctttccc 360 catttacatc tcacaggaac cttcaatgaa gataatattc cattcattta gaaattattc 420 cttttattta gaaattattt tgaaaaaact gaagctcaaa aagatgaata agttttccaa 480 ggttacacag cagatcaacg agccaagttt gaagtccaga cccagctctg agggtcgtac 540 actgccttcc ccagattcct gcacacagtg acctactacc agggccctcc tatctctctg 600 ggatccccag cctctgtctt ttgtggctgc ttcacaggaa ctccgagcta tggactctgc 660 attaggagag gaagtgcgaa gagtgtttct gtatcctctc tctcttctag gaccctaggg 720 ctcttcctgg gtctttgtgg gtggtcacaa gctttcctcc ctcaagacag cagggttgca 780 tggtcttgat agccttgtga ttcgggttct gagagatcca ggactgcaag ggaggcctag 840 acttttgata gctgcaagga ctcagccaga gatggaccgt agtgaatgct cctttttcct 900 gtagctgaaa tcagggagaa tgacatcaag cctgttcatg atgctgtcat tccaaaatct 960 agtgatgggg aaggttagaa tccataacgt acaagatgca cactggcttc agacagtttt 1020 atttaagatg tgtagaataa agaggaggtc aggctgggta gaaccagaag tatctattgc 1080 cctgttcgcg gtcacctgag ttatttctaa tgttatgtta taataaacac cacaataggc 1140 ttctcttcat agatgcaaat actttttagt attcttggta gaaattccta atgagctcag 1200 ctgtctcttc agggcttccc tgcccagtct cttaacattt aaacatgtca tttaccttaa 1260 aaacataagt gcaaaccaac tgataaaaaa caaccttgcc ttcagtctgc atcctgtccc 1320 agagacactt tctttgtgtc ctcacacgtg gagctaagct tctgacttgc ctctggtaca 1380 tccctgagga tcctctcatc ttggccatca ggaacctcta cagaaggtca aatccagtgg 1440 gttcttctca gtgcctctga cttgagttac taataacatt tgcactgtaa tccacttctt 1500 tctgatgaac taccatgtcc ttatttttct cctgtttacc tggatcctcc ttatcatcct 1560 ttaaatcacc tcttaattat catgttctct cattataccc tgagatctcg gcaattctga 1620 tttttggcac tcttcctgga aaatctcatt taacctgcgc ctgccactaa tgactctcag 1680 ttctctggcc taaactcctc tcctgagacc acccatcata cacaaatgtc tacgtattat 1740 ttctccttag atgactttca gatcttctaa gtgcaatagc cccacagtga actcagtatc 1800 ttctcccagt caggctgtct tccccctgag agaagtggct tttgccctgt tttctgaatg 1860 cctacattga agccatctgt tccccaggaa gccttccctg atgtgctgtt tgatcgcatc 1920 ttgtgtatac ccacgtatct gcacttatcc ttctgaacct gctgttgtct tgtcacttgt 1980 gtttccttct gtgacttata cgcgtctgca caacaggacg tatgtattat ttttatttga 2040 gtatttagca tctaacagtg tttgacatat agtagtcttt taatacatat ttttgtctga 2100 atggaaatga tattttgaag taaaataatc tgttccatag ctggctgatc tttggactgc 2160 agaacttgtg aaagtgtttt ttaaaaagca ttttaaaaag tacaagggac attcatgtaa 2220 taagaagatg agttttcaat aactgctaga ggactttgtg tctttttatt ttaccctctt 2280 tttcctgatg agtcctttga gtcctttaaa ctgaggagca agctaagttt cctagtgaaa 2340 tacctatagg atttgttttg tttagtttca aataccactc tttgcttggc cacttactgt 2400 gtcagggagt cattctcagt gaaaaataag acatagatca taccctctag acacttacaa 2460 ttacagtgac aaggagtcat tctcctgtcc ccacatgtca gggctgaaaa ctcacaggga 2520 aatccgtgag ttgggaagtg agagcagaag agctccatag ttccttctca ctctgatgca 2580 tttaccattc taaacccaga ctttcacata cacattcatc attttctttc atgataatag 2640 ttgcttttat cctcttatct ttgctaattc ttacaaacta ataaagacta agaaacaaaa 2700 taaattaaat cctacaggtg ttccaaactc agcaataatt tctagttggc ctctaaaaca 2760 aaaatcaaaa tataaatgta agaaaagttc agaatgctta gtacctgcgt gatgaaataa 2820 tctgtacact aaacccccga gtcatgagtt tacctataca acaaacctgc acatgtactc 2880 ctgaacataa aataaacgtt gaaatatttt taaaaaggaa acaaaagttt ggaacaaatg 2940 ccaaaataac tgtactgtac ttttgaattt atatgcccca aatgaaaaat attatcaaca 3000 aagctataca ttctacattt tcatgttcat aaactaagac agaaacttta aaactgtcaa 3060 gagcactaaa atttgaagga tattttcttc ttcctctcaa ttttgtattt ttttctacct 3120 tttctataat aagaaaaaga aaatgtccac tcccccaacc ccacgactct aaaaacaatt 3180 ttacatctgt gtcctagaag aattaagaac ttaatgggat agaaaacctc tctactagtt 3240 ccaccagtag ccatatgacc ttagcaagta attaatatgt aacttccctg catttcctta 3300 cctgtaaaat gtatgatatg tatttgcttc ataaagttat tgtgacaatt caatgagtga 3360 atatgtaaag tatttagaag gatgcctggc acaactaagt gctcaacaaa tgttagctgt 3420 cattgttatt tttactattg tgtagggtca ggatgcccag actttcaaag accaggaagc 3480 agcttgactt atcaatgata aactttttat tttgttcttc actcctttct ttttataact 3540 gctcatctgc tctgtattat ttcctttatg gtgttgctcc ttcttcttcc ccatatgtcc 3600 ttcctttgac ctcttacttt cttccttttt atattcataa gtctttattc attctctagc 3660 tttgaccact tgcatattca aactgacatt ttgtcatgtt tttctctact ttctttatgc 3720 agcggaccat gtgtcaactt atgccgcgtt tgtacagacc catagaccaa caggggagtt 3780 tatgtttgaa tttgatgaag atgagcagtt ctatgtggat ctggataaaa aggagaccgt 3840 ctggcatctg gaggagtttg gccgagcctt ttcctttgag gctcagggcg ggctggctaa 3900 cattgctata ttgaacaaca acttgaatac cttgatccag cgttccaacc acactcaggc 3960 cgccaatggt actgcctatc tttgcctctt cctctgtagc ccaactggaa gggatgagag 4020 ggcctctctg ccaccctcag actaggaagc ctaagtgccc cctgctgtgt gatcctcttc 4080 cactagtggc cgtgggctga tcccaccaca gcaagggctt tcatcctctc ttctcaggag 4140 agagaaaggt gagcagagtg aggctggtca gtggtgtgat acccctctct gtgattcaca 4200 gctgccataa aatctaaggc tgaggtagag gaccaccctc ccccaagagg tggagccttt 4260 gtgattcatc ccagaagagg gacctaacct ggtgctgtct cctcctagat ccccctgagg 4320 tgaccgtgtt tcccaaggag cctgtggagc tgggccagcc caacaccctc atctgccaca 4380 ttgacaggtt cttcccacca gtgctcaacg tcacatggct gtgcaatggg gagccagtca 4440 ctgagggtgt cgctgagagc ctcttcctgc ccagaacaga ttacagcttc cacaagttcc 4500 attacctgac ctttgtgccc tcagcagagg acttctatga ctgcagggtg gagcactggg 4560 gcttggacca gccgctcctc aagcactggg gtatgcaact gcttttctct ccataatctc 4620 ctggcatcct ctattccaaa gacctggtgt cctctgcacc agctttcccc actggccagg 4680 tctcagtcct ctcctcgtcc taacatccaa ttaactggtc cataaccttc aattcccaca 4740 accatcccag gccagaacca ccctcactac acctcctgac cctatctctt cattcttccc 4800 ccagaggccc aagagccaat ccagatgcct gagacaacgg agactgtgct ctgtgccctg 4860 ggcctggtgc tgggcctagt gggcatcatc gtgggcaccg tcctcatcat aaagtctctg 4920 cgttctggcc atgacccccg ggcccagggg cccctgtgaa atactgtaaa ggtgggaatg 4980 taaaaaagga ggtcctagaa tttgtagaat gtaaggaagg gaggaaaaat tcaatctgat 5040 aagtgttcat tgatcttcta atgggttaaa agcactcagc cacataacaa caacaacatt 5100 gataactaac tgagtagtta atatggtcag gcgctattct gagggtttac attcattaac 5160 tcactttatt ctcacaaata gtctttgagg taggtactat tattttcacc atttcacatg 5220 agagatactt acatcttttt acatacacag agatcttaag cactttgatc cagttcccac 5280 agctatgaag tagtagggct accttccaat ccagaaagtc tggatccaag actgtttatc 5340 cactgtccta ttcaccctat tttgtgaagg aaaagaccaa gttgaaattc tccaagagtc 5400 cgttgtctaa taacggagcc agatctatat ttctatacat aattacaaca cagtgtggtg 5460 ggagcctgta actacttact gtctctactt ggactcattc gatggcaatg ctcacacaaa 5520 aaatgcccct cctgagatct tataggtttc tatttatcgt aacactcacc atgctttata 5580 tttttatatg ttttgggaat tctcttagca tt 5612 //