Dbfetch
ID MN053841; SV 1; linear; genomic DNA; STD; HUM; 9780 BP. XX AC MN053841; XX DT 29-OCT-2019 (Rel. 142, Created) DT 29-OCT-2019 (Rel. 142, Last updated, Version 1) XX DE Homo sapiens isolate 17213_IMGT MHC class II antigen (HLA-DPA1) gene, DE HLA-DPA1*02:new allele, complete cds. XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-9780 RA Chou P.-C., Arnold P.Y.; RT ; RL Submitted (10-JUN-2019) to the INSDC. RL Pathology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, RL Memphis, TN 38105, USA XX DR MD5; 2d7f67a9583716013bed2d09b0d689d0. XX CC ##Assembly-Data-START## CC Assembly Method :: Assign TruSight HLA Software v. 2.1 CC Assembly Name :: HL-17-213 CC Coverage :: 229x CC Sequencing Technology :: Illumina CC ##Assembly-Data-END## XX FH Key Location/Qualifiers FH FT source 1..9780 FT /organism="Homo sapiens" FT /isolate="17213_IMGT" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT gene <1..9522 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:new" FT mRNA join(<501..623,4180..4425,4766..5047,5262..5428,8732..9522) FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:new" FT /product="MHC class II antigen" FT exon 501..623 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:new" FT /number=2 FT 5'UTR <501..523 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:new" FT CDS join(524..623,4180..4425,4766..5047,5262..5416) FT /codon_start=1 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:new" FT /product="MHC class II antigen" FT /protein_id="QFR42336.1" FT /translation="MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQ FT THRPTGEFMFEFDEDEQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTL FT IQRSNHTQAANDPPEVTVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGV FT AESLFLPRTDYSFHKFHYLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQIPETTE FT TVLCALGLVLGLVGIIVGTVLIIKSLRSGHDPRAQGPL" FT exon 4180..4425 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:new" FT /number=3 FT exon 4766..5047 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:new" FT /number=4 FT exon 5262..5428 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:new" FT /number=5 FT variation 5284 FT /gene="HLA-DPA1" FT /replace="g" FT /note="results in methionine to isoleucine substitution" FT 3'UTR join(5417..5428,8732..9522) FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:new" FT exon 8732..9522 FT /gene="HLA-DPA1" FT /allele="HLA-DPA1*02:new" FT /number=6 XX SQ Sequence 9780 BP; 2687 A; 2142 C; 1875 G; 3076 T; 0 other; ggtggacctg aaagaaagat taattatata ttttattaga tagcacattc attcttaatt 60 atcagcagaa tatttttgta aaatattgac aacataacat aaaacatgat ttaaaatata 120 gtgaccaaaa aacatcaaag atcatctgac tgtctgggat gggggtgggg ctcgggagaa 180 ggaacataat ggaaaacatt tgccgtcaga agaaggtgta acttatcttt ttacatctct 240 ttctctaact ctgaaaatga actgtgaact ggagctctct tgaccacgct ggtacctaaa 300 attctcccat ctcttcccca gcaccttcca gcgtcctctt tacccagcaa cagagaatgt 360 cagctctatg atttctctga taggtgaatc ccagccatgc tgattcctct ccacccattt 420 ccagtgctag aggcccacag tttcagtctc atctgcctcc actcggcctc agttcctcat 480 cactgttcct gtgctcacag tcatcaatta tagaccccac aacatgcgcc ctgaagacag 540 aatgttccat atcagagctg tgatcttgag agccctctcc ttggctttcc tgctgagtct 600 ccgaggagct ggggccatca agggtgagtg ctcaggagga cgcaagagcg tcggggtgag 660 tgatggggtg gttcacatca attgttgctt caggaatcac agattttagg ggctcattga 720 tctatctggt cctcatagtc tatgttccct ctggccctca taataataac agcaataaca 780 gccagaattt atgagactcc tgcatagttt ctttccccat ttacatctca caggaacctt 840 caatgaagat aatattccat tcatttagaa attattcctt ttatttagaa attattttga 900 aaaaactgaa gctcaaaaag atgaataagt tttccaaggt tacacagcag atcaacgagc 960 caagtttgaa gtccagaccc agctctgagg gtcgtacact gccttcccca gattcctgca 1020 cacagtgacc tactaccagg gccctcctat ctctctggga tccccagcct ctgtcttttg 1080 tggctgcttc acaggaactc cgagctatgg actctgcatt aggagaggaa gtgcgaagag 1140 tgtttctgta tcctctctct cttctaggac cctagggctc ttcctgggtc tttgtgggtg 1200 gtcacaagct ttcctccctc aagacagcag ggttgcatgg tcttgatagc cttgtgattc 1260 gggttctgag agatccagga ctgcaaggga ggcctagact tttgatagct gcaaggactc 1320 agccagagat ggaccgtagt gaatgctcct ttttcctgta gctgaaatca gggagaatga 1380 catcaagcct gttcatgatg ctgtcattcc aaaatctagt gatggggaag gttagaatcc 1440 ataacgtaca agatgcacac tggcttcaga cagttttatt taagatgtgt agaataaaga 1500 ggaggtcagg ctgggtagaa ccagaagtat ctattgccct gttcgcggtc acctgagtta 1560 tttctaatgt tatgttataa taaacaccac aataggcttc tcttcataga tgcaaatact 1620 ttttagtatt cttggtagaa attcctaatg agctcagctg tctcttcagg gcttccctgc 1680 ccagtctctt aacatttaaa catgtcattt accttaaaaa cataagtgca aaccaactga 1740 taaaaaacaa ccttgccttc agtctgcatc ctgtcccaga gacactttct ttgtgtcctc 1800 acacgtggag ctaagcttct gacttgcctc tggtacatcc ctgaggatcc tctcatcttg 1860 gccatcagga acctctacag aaggtcaaat ccagtgggtt cttctcagtg cctctgactt 1920 gagttactaa taacatttgc actgtaatcc acttctttct gatgaactac catgtcctta 1980 tttttctcct gtttacctgg atcctcctta tcatccttta aatcacctct taattatcat 2040 gttctctcat tataccctga gatctcggca attctgattt ttggcactct tcctggaaaa 2100 tctcatttaa cctgcgcctg ccactaatga ctctcagttc tctggcctaa actcctctcc 2160 tgagaccacc catcatacac aaatgtctac gtattatttc tccttagatg actttcagat 2220 cttctaagtg caatagcccc acagtgaact cagtatcttc tcccagtcag gctgtcttcc 2280 ccctgagaga agtggctttt gccctgtttt ctgaatgcct acattgaagc catctgttcc 2340 ccaggaagcc ttccctgatg tgctgtttga tcgcatcttg tgtataccca cgtatctgca 2400 cttatccttc tgaacctgct gttgtcttgt cacttgtgtt tccttctgtg acttatacgc 2460 gtctgcacaa caggacgtat gtattatttt tatttgagta tttagcatct aacagtgttt 2520 gacatatagt agtcttttaa tacatatttt tgtctgaatg gaaatgatat tttgaagtaa 2580 aataatctgt tccatagctg gctgatcttt ggactgcaga acttgtgaaa gtgtttttta 2640 aaaagcattt taaaaagtac aagggacatt catgtaataa gaagatgagt tttcaataac 2700 tgctagagga ctttgtgtct ttttatttta ccctcttttt cctgatgagt cctttgagtc 2760 ctttaaactg aggagcaagc taagtttcct agtgaaatac ctataggatt tgttttgttt 2820 agtttcaaat accactcttt gcttggccac ttactgtgtc agggagtcat tctcagtgaa 2880 aaataagaca tagatcatac cctctagaca cttacaatta cagtgacaag gagtcattct 2940 cctgtcccca catgtcaggg ctgaaaactc acagggaaat ccgtgagttg ggaagtgaga 3000 gcagaagagc tccatagttc cttctcactc tgatgcattt accattctaa acccagactt 3060 tcacatacac attcatcatt ttctttcatg ataatagttg cttttatcct cttatctttg 3120 ctaattctta caaactaata aagactaaga aacaaaataa attaaatcct acaggtgttc 3180 caaactcagc aataatttct agttggcctc taaaacaaaa atcaaaatat aaatgtaaga 3240 aaagttcaga atgcttagta cctgcgtgat gaaataatct gtacactaaa cccccgagtc 3300 atgagtttac ctatacaaca aacctgcaca tgtactcctg aacataaaat aaacgttgaa 3360 atatttttaa aaaggaaaca aaagtttgga acaaatgcca aaataactgt actgtacttt 3420 tgaatttata tgccccaaat gaaaaatatt atcaacaaag ctatacattc tacattttca 3480 tgttcataaa ctaagacaga aactttaaaa ctgtcaagag cactaaaatt tgaaggatat 3540 tttcttcttc ctctcaattt tgtatttttt tctacctttt ctataataag aaaaagaaaa 3600 tgtccactcc cccaacccca cgactctaaa aacaatttta catctgtgtc ctagaagaat 3660 taagaactta atgggataga aaacctctct actagttcca ccagtagcca tatgacctta 3720 gcaagtaatt aatatgtaac ttccctgcat ttccttacct gtaaaatgta tgatatgtat 3780 ttgcttcata aagttattgt gacaattcaa tgagtgaata tgtaaagtat ttagaaggat 3840 gcctggcaca actaagtgct caacaaatgt tagctgtcat tgttattttt actattgtgt 3900 agggtcagga tgcccagact ttcaaagacc aggaagcagc ttgacttatc aatgataaac 3960 tttttatttt gttcttcact cctttctttt tataactgct catctgctct gtattatttc 4020 ctttatggtg ttgctccttc ttcttcccca tatgtccttc ctttgacctc ttactttctt 4080 cctttttata ttcataagtc tttattcatt ctctagcttt gaccacttgc atattcaaac 4140 tgacattttg tcatgttttt ctctactttc tttatgcagc ggaccatgtg tcaacttatg 4200 ccgcgtttgt acagacccat agaccaacag gggagtttat gtttgaattt gatgaagatg 4260 agcagttcta tgtggatctg gataaaaagg agaccgtctg gcatctggag gagtttggcc 4320 gagccttttc ctttgaggct cagggcgggc tggctaacat tgctatattg aacaacaact 4380 tgaatacctt gatccagcgt tccaaccaca ctcaggccgc caatggtact gcctatcttt 4440 gcctcttcct ctgtagccca actggaaggg atgagagggc ctctctgcca ccctcagact 4500 aggaagccta agtgccccct gctgtgtgat cctcttccac tagtggccgt gggctgatcc 4560 caccacagca agggctttca tcctctcttc tcaggagaga gaaaggtgag cagagtgagg 4620 ctggtcagtg gtgtgatacc cctctctgtg attcacagct gccataaaat ctaaggctga 4680 ggtagaggac caccctcccc caagaggtgg agcctttgtg attcatccca gaagagggac 4740 ctaacctggt gctgtctcct cctagatccc cctgaggtga ccgtgtttcc caaggagcct 4800 gtggagctgg gccagcccaa caccctcatc tgccacattg acaggttctt cccaccagtg 4860 ctcaacgtca catggctgtg caatggggag ccagtcactg agggtgtcgc tgagagcctc 4920 ttcctgccca gaacagatta cagcttccac aagttccatt acctgacctt tgtgccctca 4980 gcagaggacg tctatgactg cagggtggag cactggggct tggaccagcc gctcctcaag 5040 cactggggta tgcaactgct tttctctcca taatctcctg gcatcctcta ttccaaagac 5100 ctggtgtcct ctgcaccagc tttccccact ggccaggtct cagtcctctc ctcgtcctaa 5160 catccaatta actggtccat aaccttcaat tcccacaacc atcccaggcc agaaccaccc 5220 tcactacacc tcctgaccct atctcttcat tcttccccca gaggcccaag agccaatcca 5280 gattcctgag acaacggaga ctgtgctctg tgccctgggc ctggtgctgg gcctagtggg 5340 catcatcgtg ggcaccgtcc tcatcataaa gtctctgcgt tctggccatg acccccgggc 5400 ccaggggccc ctgtgaaata ctgtaaaggt gggaatgtaa aaaaggaggt cctagaattt 5460 gtagaatgta aggaagggag gaaaaattca atctgataag tgttcattga tcttctaatg 5520 ggttaaaagc actcagccac ataacaacaa caacattgat aactaactga gtagttaata 5580 tggtcaggcg ctattctgag ggtttacatt cattaactca ctttattctc acaaatagtc 5640 tttgaggtag gtactattat tttcaccatt tcacatgaga gatacttaca tctttttaca 5700 tacacagaga tcttaagcac tttgatccag ttcccacagc tatgaagtag tagggctacc 5760 ttccaatcca gaaagtctgg atccaagact gtttatccac tgtcctattc accctatttt 5820 gtgaaggaaa agaccaagtt gaaattctcc aagagtccgt tgtctaataa cggagccaga 5880 tctatatttc tatacataat tacaacacag tgtggtggga gcctgtaact acttactgtc 5940 tctacttgga ctcattcgat ggcaatgctc acacaaaaaa tgcccctcct gagatcttat 6000 aggtttctat ttatcgtaac actcaccatg ctttatattt ttatatgttt tgggaattct 6060 cttagcatta gacagtgaac ttccatgcag atgaccacat ctaattcatt attattattg 6120 ttattcatgc tggacctcag gtacaaaagg ttaagaactt ctcagttcat tatactgtca 6180 tcactggtgc ctccgaactc tctctctctc tcgatttatt tggtcccttt tatctccagt 6240 ccttactccc atatctaacc tcttacccct acctcatagg taaacatttt aatgaatttg 6300 atgtttcctt ttatttgcat agatgctccc taatatgtag tagtgtccag tgtacatgta 6360 tttttaatta accaaaatgg cattaaatta tagatctaat tttgtatatc cagtttgtat 6420 cttccaaatc ttccatagta ttttcctcta tatgtccatg cattagtcca ttttgcattc 6480 ctataaagga ataaaggaat atctgaagtt acctaattta tgaagaaaag agctttaaat 6540 ggcttacaga tctgcaggct gtccatgaaa catggcacca gcatctgctt ctgttggggg 6600 attctggaag cttttactca tggtggaagg caagtggagc cagtgcatca catggtcata 6660 gagggagaaa gagacataga aagaggtgcc aggctctttt aacaacgagg tttcacgtgc 6720 actaatagag tgagaactca ctcattaccc tggggcgggc accaagccat tcatgaggga 6780 gtctcctcca tgattcaaat acctcccacc aggccccacc tgcaacactg ggtatcaatt 6840 ttcaacatga gatttggaag ggacaaatat ccaaatcata ttaatccaca tatctatatt 6900 gctcctggga tacctggatc acccctggtt ctctactatt gcaagcgatg ctcgtatctc 6960 acatggaact gcatatgcat gtgggcctga cctgcatccc tggaatgtat gtatcctaga 7020 aaggggttgc agggttgctg gagatgcagc tccttaattt gactaaatac tgctcatctt 7080 ctcatcagaa tggctgtact catctgtgct tcctttgtca gtacctgaaa tgtcctgcaa 7140 ctcctaaatg cacatcaaca ctggacatta tccagttttc taacttttgc caatttcatt 7200 tgcataaaga aatatgctgt tttattttgc atttctttaa ttactaataa ttggggctat 7260 aattaggact gattaaccac ttgggggttc cttttctata aattgcctgt tcacattcat 7320 tgcccatttt tgtattatgt gcttctatca ttttcttatt gatttgcaag tgatacttac 7380 acagtcctgc tagtagtccc ttgtcagttt taggcattgc aaatgttttc ccctaatctg 7440 acttctggta actttctcct tggtttcctt tattgaagag aaatccttaa tattttgtgt 7500 tgaagtccat caactgtatt tttgtttatg catctttttt aaaagaaatc ttccctgtac 7560 tgagatatca aagatactct taaaacatct cctacagttt taaatttcac atgtactact 7620 ttaattcatt tgggattcat ctttgtgttt gatggggatc atgttttatt tttctctata 7680 taatgggcca gtgtgttccc acaactacta aatagttcac cttttcccca taagctagtg 7740 gtgtctcctt tgctatactg aaagctccca ttacagatgg gcctgtgtct gagttccatc 7800 ttgttccact gttctgtttg tctcttcttg tgccagtgtc ctagtgtttt gattactatg 7860 acattgtagt gtgtgttagt atccagtagg aaaaattctt ctttattttt ctttgttcac 7920 acacatttat aatgatatct ataatgattt gtaacagaat gaagtgaatg tagaatgtca 7980 gatgttaaga ggaagaatgg aaaggagggc tggaattagg gtgatgtaag ggatgcactt 8040 gacttaggtg caaaatttgg gagatgccaa aagaactcag taataaatca tattttaatg 8100 aaatatcttg aaaaagcaaa attaatgcaa agatacatga ttgacaaaat atcaaaagag 8160 gattattcaa cgaaaatgga gaagaagcag agaggcagaa taattaggag aatatgttgt 8220 cacataagcc aaggaattaa agaattccag gaaggaggaa gtactgctgt cagatgttca 8280 acagaggtca ttttagaaaa tttaccttgg ttttgaaatc ctttcaaaga gcagtttaca 8340 caatgtgaac aagtatcctt ccttcattgc catcattgat atggtttgga tatttgtccc 8400 ttccaattct cattccaggg ttaagcttct tctctgccct cagtaatgtg gcccttcccc 8460 ttgtcaggat attttggaga catgaagcat gtgggatgcc ctcaaagtca gctggggttt 8520 gagggtgaaa ttcaatgact ttagtgaact ccttggctcc tatgtgctgt tcacctggag 8580 gaccagggtt tgtgcaggga tgaccacctt ctccctggga gctgaacagg gcagagaaat 8640 gggaagctcg ggtacaaagg gagtgggaaa gatgggtttg ggcttgcagt actgaaccca 8700 ggaatgacag taactgtgtg tgttgctgca ggtgacaaaa tatctgaaca gaagaggact 8760 taggagagat ctgaactcca gctgccctac aaactccgtc acagcttttc ttctcacttc 8820 atgtgaaaac taccccagtg gctgactgaa ttgctgaccc ttcaagctct gtccttatcc 8880 gttaccttaa agcagtcatt ccttagtaaa gtttccaaca aatagaaatt aatgaataaa 8940 tgttgacact ttgatagcac tgatatggag attatccttt cattgagcct tttatcctct 9000 ggtcttcttt gaaaaacccc tcactgtcac cttcctgaga atactctaag accaataaat 9060 acttcagtat ttcagagctg ggagactctg agtcattctt actggaagtc taggaccagg 9120 tcacatgtga atactatttc ttgaaggtgt ggtttcaacc tctattgcag atgtagttac 9180 taaaggttct gatcccacct gaatggaaag gtctgaggat attgattcag ccctgggttc 9240 ttctctaact acaggatagg gtggggcaga gaaaggatat tggggggaaa ttttacttgg 9300 atgaagattt tcttggatgt agtttgaaga ctgcagtgtt tgaagtctct gagggaagag 9360 atttggtctg tctggatcaa gatttcaggc agattaggat tccattcaca gcccctgagc 9420 ttccttccca aggctggatt gtaattatag caatatttca tggaggattt tttctacatg 9480 ataaactaag agccaagaaa taaaatttta aaaatgccct cattcattgc aatttttacc 9540 agccatagtc actccatgtg ggagaactta aatcatgatt accagagctt ccaaaagttt 9600 gagaatagtg atgattatga agaaaaatat cttatttgag caaggatttt gtttctttat 9660 gggtgttcat tagatattat gatgaaaaaa gcacgaaatg gtaaaaatgc agataaatat 9720 aaaaacatgt tttctaggtt tctttttatt tttaagttaa aaaaggaatt gtttaaagtg 9780 //