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EBI Dbfetch

ID   M31944; SV 1; linear; genomic DNA; STD; HUM; 6581 BP.
XX
AC   M31944;
XX
DT   26-NOV-1990 (Rel. 25, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 9)
XX
DE   Human MHC class I processed pseudo-leukocyte antigen (HLA-H) gene, complete
DE   cds.
XX
KW   cell surface antigen; cell surface glycoprotein; class I gene;
KW   integral membrane protein; leukocyte antigen;
KW   major histocompatibility complex; pseudogene.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-6581
RX   PUBMED; 2294403.
RA   Chorney M.J., Sawada I., Gillespie G.A., Srivastava R., Pan J.,
RA   Weissman S.M.;
RT   "Transcription analysis, physical mapping, and molecular characterization
RT   of a nonclassical human leukocyte antigen class I gene";
RL   Mol. Cell. Biol. 10(1):243-253(1990).
XX
DR   MD5; f6528294e77583e39bfe4140e33e7c9c.
DR   EuropePMC; PMC1853057; 9777937.
DR   IMGT/HLA; H*01:01:01:03; HLA02548.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..6581
FT                   /organism="Homo sapiens"
FT                   /map="6p21.3"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:9606"
FT   exon            <1196..1268
FT                   /gene="HLA-H"
FT                   /number=1
FT                   /note="pseudo-MHC leukocyte antigen"
FT   prim_transcript <1196..>4089
FT                   /note="HLA-H mRNA and introns"
FT   CDS             join(1196..1268,1393..1662,1904..2179,2763..3037,
FT                   3140..3256,3697..3729,3872..3918,4085..4089)
FT                   /pseudo
FT                   /codon_start=1
FT                   /gene="HLA-H"
FT                   /product="leukocyte common antigen"
FT   intron          1269..1392
FT                   /note="HLA-H intron A"
FT   exon            1393..1662
FT                   /pseudo
FT                   /gene="HLA-H"
FT                   /number=2
FT                   /note="pseudo-MHC leukocyte antigen"
FT   intron          1663..1903
FT                   /note="HLA-H intron A"
FT   exon            1904..2179
FT                   /pseudo
FT                   /gene="HLA-H"
FT                   /number=3
FT                   /note="pseudo-MHC leukocyte antigen"
FT   intron          2180..2762
FT                   /note="HLA-H intron A"
FT   exon            2763..3037
FT                   /pseudo
FT                   /gene="HLA-H"
FT                   /number=4
FT                   /note="pseudo-MHC leukocyte antigen"
FT   misc_feature    3029..3031
FT                   /gene="HLA-H"
FT                   /note="in frame stop codon"
FT   intron          3038..3139
FT                   /note="HLA-H intron A"
FT   exon            3140..3256
FT                   /pseudo
FT                   /gene="HLA-H"
FT                   /number=5
FT                   /note="pseudo-MHC leukocyte antigen"
FT   intron          3257..3696
FT                   /note="HLA-H intron A"
FT   exon            3697..3729
FT                   /pseudo
FT                   /gene="HLA-H"
FT                   /number=6
FT                   /note="pseudo-MHC leukocyte antigen"
FT   intron          3730..3871
FT                   /note="HLA-H intron A"
FT   exon            3872..3918
FT                   /pseudo
FT                   /gene="HLA-H"
FT                   /number=7
FT                   /note="pseudo-MHC leukocyte antigen"
FT   intron          3919..4084
FT                   /note="HLA-H intron A"
FT   exon            4085..>4089
FT                   /gene="HLA-H"
FT                   /number=8
FT                   /note="pseudo-MHC leukocyte antigen"
XX
SQ   Sequence 6581 BP; 1539 A; 1647 C; 1794 G; 1601 T; 0 other;
     gaattcttag gtttaaatac attgttttat ggattttaat acatccatct acagagccta        60
     gcagggtgtc cttggcagtt ggcctttaat acctcatgtg ggtctgccta aaaactaatt       120
     ttttaatgtt aatcaggttt aaaaattact aagtgttcct ataaaatata cacaacactt       180
     agcagtggat acttcctaaa aacaggcagt gcatgagcac tagtgagggg cattgcgact       240
     acattgaaca gttgcaactt tgaggtgaat aaagcctgta ctgactcctg gttgcaacgt       300
     acctggttgc aaagtacaca ggtgtgctac tttgtattga ggagatatcc tggactcaca       360
     cagaaactca gagctatgga atgatggcaa atttaaaata tgacaagcgg gagtcacagg       420
     tacactgcaa aagtgaaact tagaagcttt gtgagtcctg ttctaacgct tttgggcaca       480
     tttatacatc atggggccaa agtcacattt tttaccgatt agattcctga tcattcaggg       540
     gttaccaagg ttctgctatc caatgtattt aataaacaaa taaataaata aactggtctc       600
     tattctgtct catgcactca ggcacaactt ttcccaataa aaaaaaaaaa aaaaggaaaa       660
     caaaaaacag tttctacacc tccattccca gagcaagctc actctctgtc accaaactcc       720
     gtgggtgact tttcttctag aagagtccag gtggacaggg agtccaggtt cagggacgga       780
     gattcctgga tgaaaagtga agggagaggg acagggccca tgccgagggt ttcttcctgg       840
     tttctcagac agctcctggg ccaagactca gggaaacact gagacagagc gcttggcaca       900
     ggaggagcgg ggtcagggcg aagtcccagg gccccaggcg tggctctcag ggtctcaggc       960
     cccgaaggcg gtgtatggat tggggaggcc ccgccttggg gattcgccac ctccgcagtt      1020
     tctcttcttc tcacaacctg cgacgggtcc tttttcctgg atactcagga agcgggcaca      1080
     gttctcattc ccactaggtg tcgggtttct agagaagcca atcggtgccg ccgcggtccc      1140
     ggttctaaag tccccacgca cccaccggga ctcagattct ccccagacgc cgaggatggt      1200
     gctcatggcg ccccgaaccc tcctcctgct gctctcaggg gccctggccc tgacccagac      1260
     ctgggcgcgt gagtgcaggg tctgcaggga aatggtcggg aggagcgagg ggcccgcccg      1320
     gcgggggcgc aggacccagg gagccgcgca gggaggaggg tcgggcgggt ctcagctcct      1380
     cctcgctccc aggctcccac tccatgaggt atttctacac caccatgtcc cggcccggcc      1440
     gcggggagcc ccgcttcatc tccgtcggct acgtggacga tacgcagttc gtgcggttcg      1500
     acagcgacgc cgcgagccag aggatggagc cgcgggcgcc gtggatggag cgggaggggc      1560
     cggagtattg ggaccggaac acacagatct gcaaggccca ggcacagact gaacgagaga      1620
     acctgcggat cgcgctccgc tactacaacc agagcgaggg cggtgagtga ccccggcccg      1680
     ggacgcaggt cacgacccct ccccatcccc cacggagggc cgggtcgcct cgagtctctg      1740
     ggtccgagat cctccccgaa accgcgggac cccgagaccc ttgacctggg agaggcccag      1800
     gcgcctttac ccggtttcat tttcagttta ggccaaaatc cccgcgggtt ggtcggggca      1860
     gggcggggct cgggggaccg ggctgaccgc gggggcgggc caggttctca caccatgcag      1920
     gtgatgtatg gctgcgacgt ggggcccgac gggcgcttcc tccgcgggta tgaacagcac      1980
     gcctacgaca gcaaggatta catcgctctg aacgaggacc tgcgctcctg gaccgcggcg      2040
     gacatggcag ctcagatcac caagcgcaag tgggaggcgg cccgtcaggc ggagcagctg      2100
     agagcctacc tggagggcga gttcgtggag tggctccgca gatacctgga gaacgggaag      2160
     gagacgctgc agcgcgcggg taccaggggc cacagggcgc ctcccggatg gcctgtagat      2220
     ctccggggct ggcctcccac aagaaaggga gacaaatggg accaacacta taatatcgcc      2280
     ctccctctgg tcctgaggga gaagaatcct cctgggtttc cagagagtga ctctgagggt      2340
     ccgccgtgct ctttgacaca attaagggat gaaatctctg aggaaatgaa gggaagacaa      2400
     tccctggaat actgatgagt ggttcccttt gacactggca gcagcttggg cccgtgactt      2460
     ttcctctcag gccttgttct ctgcttcaca ctcaatgtgc ctgggggtct gagtccagct      2520
     cttctgagtc cctcagcctc cactcaggtc aggaccagaa gtcgctgttc cctcctcagg      2580
     gactagaatt ttccacggaa taggagttta tcccaggttc tggtgtccag gctgttgtct      2640
     gggttctgtg ctcccttccc caccccaggc gtcctgtcca ttctcaagat ggccacatgc      2700
     gtgctggtgg agtgtcccat gacagatgca aaatgcctga attttctgac tcttcctgtc      2760
     agaccccccc aagacacata tgacccacca ccccatctct gaccatgagg ccaccctgag      2820
     gtgctgggcc ctgggcttct accctgcgga gatcacactg acctggcagc gggatgggga      2880
     ggaccagacc cacacacgga gctcatggag accaggcctg caggggatgg aaccttccag      2940
     aagtgggcgg ctgtggtggt gccttctgga gaggagcaga gatacacctg ccatgtgcag      3000
     catgagggtc tgccagagcc cctcaccctg agatggggta aggagggaga tgggggtgtc      3060
     atgtccctta ggaaaagccg gagcctctct ggagagcttt agcagggtca gggtccctca      3120
     ccttcccccc ttttcccaga gccatcttcc cagcccacca tccccatcgt gggcatcgtt      3180
     gctggcctgg ttctacttgt agctgtggtc actggagctg tggtcgctgc tgtaatgtgg      3240
     aggaagaaga gctcaggtaa ggaaggggtg aggagtgtgg tctgagattt cttgtctcac      3300
     tgagagttcc aagccccagg tagaagtgcc ctgcctggtt actgggaagc accatccaca      3360
     ctcatgggcc tacccagcct gggccctgtg tgccagcact tactcttttg taaagcacct      3420
     gttacaatga gggacagatt tatcaccttg atgactgtgg tgatgggacc tgatcccagc      3480
     agtcacaagt cacaggggaa ggtccccgag gacagacctc agaagggcgg ttggtccagg      3540
     acccacatct gctttcctca tgtttcctga tcccgccctg ggtctgcagt tgcacatttc      3600
     tggaaacttc tctggggtcc aagacttgga ggttcctcta ggaccttatg gccctggctt      3660
     ctttctggca tctcacagga cattttcttc ccacagatag aaaaggaggg agctactctc      3720
     aggctgcaag taagtatgaa ggaggctgat ccctgaaatc ctttggatat tgtgtttggg      3780
     agcccatggg ggagctcacc caccccacaa ttcttcctct agccacatct actgtgggat      3840
     ctgaccaggt cctgttttta ttctactcca ggcggcaaca gtgcccaggg ctctgatgtg      3900
     tctctcacgg cgtgaaaggt gagaccttgg ggggcctgat gtgtgggggg tgttgggggg      3960
     gaacagtgac acagctgtgc tatggggttc tttgaatttg atgttttgag catgcgatgg      4020
     gctgccaaag tgtcatccat tactgggaca gatatgaatt tgttcatgaa tattttttct      4080
     atagtgtgag acagctgcct tgtgtgggac tgagaggcaa gatttgttca caccttccct      4140
     ttgtgacttg aagaaccctg actttctgca aaggcacctg aatgtgtctg tgttcctgta      4200
     ggcataatgt gtggaggagg ggagaccaac ccaccctcat gtccaccatg accctcttcc      4260
     ccacgctgat ctgtgttccc tccccaatca tctttcctgt tccagaggcg gggctgagat      4320
     gtctccatct ttttctcaac tttatgtgca ctgagctgta acttcttact tccctcttaa      4380
     aattagaatc tgagtaaaca tttacttttt caaattcttg ccatgagagg ttgatgactt      4440
     aattaaagga gaagattcct aaaatttgag agacaaaata aatggaacac atgagaacct      4500
     tccagagtcc atgtgtttct tgtgctgatt tgttgcaggg gaggagaata gatgggctgt      4560
     gcctagtggg tgctcaggcc agtatggact ttatgtggtc actgctcagc tgggtcatct      4620
     ttgctccttc attctccttg gcccttcagt agaaccttgt cccaccacca cctgtgatca      4680
     cagggagttg gatgtcacct agggtggtcc ctgcatacaa atctcattgt ggtatcaaga      4740
     gactaatttt cagacctgtc cagctcttgc cctcctccca gggctctttc ctggattgta      4800
     gttttcatct tgtctccaat ctttttaaag gaagcagatt ctgaaatttg cagagaggag      4860
     gggtcccata gtttctcatc atagtgaact ttctgttgga gctcctcttc tgctctccta      4920
     ctcttcttcc tgccctgagt tgtagtaatc ctagtgctgg ctccaatcca aactcatgga      4980
     tttacaaagc agagtctaat ttagattcat acgtggttgg aaaattgtac ccataagcct      5040
     agggttatct ttcctgaaga gaaaatatgg ttgtgtgctg cagtgtgcag agggttggtg      5100
     tgggaggagg tagggaggga gggaggacac acaagcagtc ctggtgagaa aagcactggc      5160
     ggcatcgatg tccacatgag atgatgttgt tctttagctg ccacaaaaca gcatttgccc      5220
     tgaggctacc ttaacaaaga tattggcttt agaatagaga agtgctctac agtgatcatt      5280
     cattcaactg acatttgttg tctgctaggg atatgactgc tttttgcgtt ttagaaagca      5340
     tcattaaggt gaaaacagaa aaatttctgg tgttgtggta catatgttct agatgctagc      5400
     ttgtctaacc cgtagctcgc aggctgaatg tggcccagga cagttttgaa tgtgaggagt      5460
     ttttgctttt ctgtggcgga cctgagacct ggagtgagtg cacccacctc cctcaggatc      5520
     aggagtgaat gctttaggaa ccctcctttg cagcgacctg caaaagatag agggcacggt      5580
     tactgtgaga acccagagta gcagccaaag gggctcaacc ttcatggagt tttgggaaag      5640
     gttagtaaaa ggtggtgtcc cagcgtcaga acagatgggc agccagcgag ggcactgctt      5700
     catatctatg atgggaatgc aagaattgag gagcaggaga ctgagggtgt ttgatcaaat      5760
     acaaagtcat gatcccagtc tcaattccta gacttcagcc aagcttcaga ttcagacagt      5820
     ggggcttaag gaggccagga aataaacctg gacacattat ggcccactgt gggaccactg      5880
     ggttcataaa cccagtcctg gttatctccc cattctccac atgcataatt ggccttgatg      5940
     cactggcaaa gggagtcacc cccacactac atccctagtc tggagagtaa gggctatcat      6000
     tgtgctgaag ccaaagggaa tcatctaaaa cttccctcat cccagccaag ccagaagcaa      6060
     tattgcgccc caggtgggac ttcaggaggg tactgcaggt attgtagggg tggcactgcc      6120
     attagagagc tgaaggatgg ggggtggtgt tgggattgcc tattatctcc atataattca      6180
     gcagtctgtc cctgaagaag cctgataaag aatgaatgga attactccag acttgaccaa      6240
     gtaggagtcc tgattgcagc tgccatgctg gctggatatc actgcttggg gagattaata      6300
     aggcctcagg cacatggcaa acagccatgc atttggtgag tgcattcttt cccattccat      6360
     ttagaaaatg gatatggaat gattcacatt cacatgggat ttataataca tttattgata      6420
     gcttgcctca gggctacttt aactcctcaa ccttctataa atatcacctt aagagatctg      6480
     gacaaatcag acatctcaca gaatactaaa tctcttcatt tcattggcaa tatcacatag      6540
     attgggatgg atgagtaaga ggaggaaagt acgctgaatt c                          6581
//


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