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EBI Dbfetch

ID   M30694; SV 1; linear; genomic DNA; STD; HUM; 942 BP.
XX
AC   M30694;
XX
DT   26-NOV-1990 (Rel. 25, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 11)
XX
DE   Human MHC class II HLA-DRB4-null beta chain pseudogene (DQw9,DR7,
DE   DRB4-null,Bw57), exons 2a and 2b.
XX
KW   cell surface glycoprotein; class II gene; integral membrane protein;
KW   major histocompatibility complex; pseudogene.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-942
RX   DOI; 10.1007/BF00661221.
RX   PUBMED; 2303277.
RA   Sutton V.R., Knowles R.W.;
RT   "An aberrant DRB4 null gene transcript is found that could encode a novel
RT   HLA-DR beta chain";
RL   Immunogenetics 31(2):112-117(1990).
XX
DR   MD5; 2da11c394d6a536d50e36d2fb48f4313.
DR   IMGT/HLA; DRB4*01:03:01:02N; HLA00909.
XX
CC   Draft entry and computer-readable sequence for [1] kindly submitted
CC   by R.W.Knowles, 13-DEC-1989.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..942
FT                   /organism="Homo sapiens"
FT                   /map="6p21.3"
FT                   /isolate="DB"
FT                   /mol_type="genomic DNA"
FT                   /haplotype="DQw9,DR7,DRB4-null,Bw57"
FT                   /cell_line="B cell line DBB 10W#9052"
FT                   /db_xref="taxon:9606"
FT   intron          <1..44
FT                   /gene="HLA-DRB4"
FT                   /number=1
FT                   /note="G00-120-645"
FT   CDS             join(45..199,650..902)
FT                   /pseudo
FT                   /partial
FT                   /codon_start=3
FT                   /gene="HLA-DRB4"
FT                   /product="MHC class II HLA-DR-beta-4-null"
FT                   /db_xref="PSEUDO:CAB25601.1"
FT   exon            45..199
FT                   /gene="HLA-DRB4"
FT                   /number=2
FT                   /note="2a; G00-120-645"
FT   intron          200..649
FT                   /gene="HLA-DRB4"
FT                   /number=3
FT                   /note="2a; G00-120-645"
FT   misc_feature    631..632
FT                   /note="MHC HLA-DRB4-null beta chain mutant splice site"
FT   exon            650..902
FT                   /gene="HLA-DRB4"
FT                   /number=3
FT                   /note="2b; G00-120-645"
FT   intron          903..>942
FT                   /gene="HLA-DRB4"
FT                   /number=3
FT                   /note="2b; G00-120-645"
XX
SQ   Sequence 942 BP; 181 A; 240 C; 321 G; 200 T; 0 other;
     gcaccctaat gtaattgaga tcatcctttt attctctgtt ccagaactcc acacttctga        60
     cgtttctcat tcctgtctaa gctcttgtgt gtttggtttt tggccatcac gttcactgct       120
     ctttaagctc ccccagcgga gtggagaggt ctgttttcct ttgtttggat tcctagaggc       180
     agcgcagacc aggcacaagg tcagcactaa ggaagggttc acgggatgaa cacggtgggt       240
     gctgttgaag gaaccggtaa agcgtgtggg atgagaggag cagagagtgt ctttcaggtg       300
     aagactccca gaaggaggcc gcgtgggccg cggtgctggg cggatcctcc tccagctcct       360
     gcctggagtt ctccagaaca ggctggaggc agggaggggg tccccaaaag cctgaggatc       420
     agaaggggtt ttcccgcctg gtcccccaga ccccggttcg cctcaggaag actgaggacg       480
     agcccctggg ctgctggtgg tgggcgttgc gggtggggcc ggttaaggtt cccagcgccc       540
     gcaccccgcc cagggagtcc gggttggtgg cgtcgctgtc agtgtcttct caggaggccg       600
     cccgtgtgac cggatcgttc gtgtccccac aacacgtttc ttggagcagg ctaagtgtga       660
     gtgtcatttc ctcaatggga cggagcgagt gtggaacctg atcagataca tctataacca       720
     agaggagtac gcgcgctaca acagtgacct gggggagtac caggcggtga cggagctggg       780
     gcggcctgac gctgagtact ggaacagcca gaaggacctc ctggagcgga ggcgggccga       840
     ggtggacacc tactgcagat acaactacgg ggttgtggag agcttcacag tgcagcggcg       900
     aggtgagcat ggtggagggc ggggcctggg tccctgtgag cg                          942
//


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