Dbfetch
ID LT719001; SV 1; linear; genomic DNA; STD; HUM; 11540 BP. XX AC LT719001; XX DT 28-JAN-2017 (Rel. 131, Created) DT 28-JAN-2017 (Rel. 131, Last updated, Version 1) XX DE Homo sapiens HLA-DPB1 gene for MHC class II antigen, cell line DE DKMS-LSL-DPB1-1668, allele HLA-DPB1*02:new XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-11540 RA Albrecht V.; RT ; RL Submitted (25-JAN-2017) to the INSDC. RL Research and Development, DKMS LIFE SCIENCE LAB, Fiedler Str. 43, Saxony, RL 01307 Dresden, GERMANY. XX RN [2] RA Lang K., Schoefl G., Schmidt A., Lange V.; RT "Complementing the HLA-DPB1 Database: Full-Length Gene Characterization of RT all Common and Well-Documented Alleles"; RL Unpublished. XX DR MD5; 05cdb2023773da65078ddff48b14ab20. XX FH Key Location/Qualifiers FH FT source 1..11540 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /cell_line="DKMS-LSL-DPB1-1668" FT /db_xref="taxon:9606" FT exon 1..466 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*02:new" FT /number=1 FT CDS join(367..466,5003..5266,9289..9570,10118..10228, FT 10558..10577) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*02:new" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /db_xref="GOA:I4EC17" FT /db_xref="InterPro:IPR000353" FT /db_xref="InterPro:IPR003006" FT /db_xref="InterPro:IPR003597" FT /db_xref="InterPro:IPR007110" FT /db_xref="InterPro:IPR011162" FT /db_xref="InterPro:IPR013783" FT /db_xref="InterPro:IPR014745" FT /db_xref="InterPro:IPR036179" FT /db_xref="UniProtKB/TrEMBL:I4EC17" FT /protein_id="SJK83316.1" FT /translation="MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECY FT AFNGTQRFLERYIYNREEYARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDR FT MCRHNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQ FT EETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSA FT RSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA" FT intron 467..5002 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*02:new" FT /number=1 FT exon 5003..5266 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*02:new" FT /number=2 FT intron 5267..9288 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*02:new" FT /number=2 FT exon 9289..9570 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*02:new" FT /number=3 FT intron 9571..10117 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*02:new" FT /number=3 FT exon 10118..10228 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*02:new" FT /number=4 FT intron 10229..10557 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*02:new" FT /number=4 FT exon 10558..11540 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*02:new" FT /number=5 XX SQ Sequence 11540 BP; 3143 A; 2539 C; 2997 G; 2861 T; 0 other; taatccctgt agatgggcca gcagaatatt tgagatcacc ttcagagcaa agaaaacgca 60 taatctcgcc aaacatcatg acttatctga ctggttaaaa tgagtatcac tgtctttcct 120 ccgtcatctt aagtgcatca caggctttat attttcagac ctttcatact aactttctgc 180 ctagtgagca atgactcata caaagctcag tgtccattgg ttcttttctc agactctgtc 240 caatcccagg gtcacagaag actacttggg ttcatggtct ctaatatttc aaacaggagc 300 tccctttagc gagtccttct tttcctgact gcagctcttt tcattttgcc atccttttcc 360 agctccatga tggttctgca ggtttctgcg gccccccgga cagtggctct gacggcgtta 420 ctgatggtgc tgctcacatc tgtggttcag ggcagggcca ctccaggtaa gagccgagct 480 gccattcttg gagggtctgg ctcagggaac aattcctagg ggacgttatc tttaagggat 540 caaattctga gacaggctgc gggggctcct gccctaaggc agtgtcctct cttcccagct 600 agagaaagag gttcatcccc tataggatag cttgctaccc tactggccta ttctctctcc 660 aaggacatgg gtacagtaaa cagagagagg tgcccagtgg tcagtatgct tgtctttggg 720 gaaaatggga ccaagaggtc ctggataacc ttggacagac aaggtttgca gagagagaag 780 ttggcaagtg caggctcctg ggcgtgttca tgtctgcatc cagcctggag gggactcagg 840 cagagagccc taagctggag tgtccaggct ctgaggatca ctgaggattc agtgctcacg 900 aagaatgcct cttattcccc agggtggagc aggagcccac atcccttgga caattaagga 960 gagaagggag ggagggggat aggttttagc ccctgaaggc attctcatta aaggtacttc 1020 tcccagcctc cccagaactt ggttagggta ctagagtggg ttgcgacttg taggaagaat 1080 gagatgaggt tgtgtgggtg catgacaggg attgagtgta ggttatcaga cagccaagga 1140 agcagtaacc aagtgaaaaa tctcttcttc ctgctgcctc cctgtggctg gtgtaatatt 1200 atggcatcta tgatccattg tttttctctc aggatactct caggatattt ctttttatat 1260 atatatatac tttaagttct agggtacatg tgcacaacgt gcaggtttgt tacatatgta 1320 tacatgtgcc atgttggtgt gctgcaccca ttaactcgtc atttacatta ggtatatttc 1380 ctaatgctat ccctcccccc tccccccacc ccacaacagg ccccggtgta tgatgttccc 1440 cttcctgtgt ccatgtgttc tcattgttca gttcccacct atgagtgaga acatgtggtc 1500 tttggttttt tgtccttgca atagtttgct gtgaatgatg gtttccagct tcctccatgt 1560 ccctacaaag gacatgaact catccttttt tatggctgca cagtattcca tggtgtatat 1620 gtgtgcattt tcttaatcca gtctatcact gatggacagt tgggttggtt ccaagtcttt 1680 gctattgtga atagtgccgc aataaacata tgtgtgcatg tgtctttata gcagcatgat 1740 ttataatcct ttgggtatat acccagtaat gggatggctg ggtcaaatgg tatttctagt 1800 tctagatcct tgaggaattg ccacactgtc ttgagatacc atctcacacc agttaaaatg 1860 gcgatcatta aaaagtcagg aaacaacagg tgctggagag gatgtggaga aataggaaca 1920 cttttactct gttggtggga ctgtaaacta gttcaaccat tgtactctca ggacatttct 1980 agtccaaatt tacaccaaca ctctgagagg aaggactgca aagtaggtac cttagttttc 2040 cactgacttc cacttttcct gcttacaccc ttcctcctag acctctccac acccctccta 2100 ggacacacct aaaaggtact gacatcatgt cacctcctca tctttcaggg tagcaaggtt 2160 ggaatctcct gaatacagcc cctcaagccc taaaacctct tatctattac ctcgggttca 2220 ttgtccagga aggggaggag aacttgaact tgtagtcaca gaagggtgct gagaactaac 2280 cagcaggacg gctcagccct gggaactgca gaggggtgag gctggggaga gaggaggctg 2340 gagcagcact ggtgacactg aacagtgtca ggaggaagtg acggatgcag cgcccccatc 2400 ccataggcag agctgtcatg tgggatgagg gacagtgttg ggagccacca aggaaaccca 2460 gaggtggggg agcagagagc agaagggggc atgtgatgct gggcagtgaa agggaggaca 2520 ggcaaaggct gggttgaggt ttgtaggggg aatgagatga ggcagtggag ccatgtgaca 2580 gggactgagg gtagattact ggagctccct gcgtagaatg aatgttcaat caaaacctgc 2640 tggagggaga gctggagcca taggggagtg ggtaaagtgg gcagggctga ttccacaatt 2700 ccctgcatgc tcccccaact ccacacacat ccccaacctc aaacagggca caagaccaaa 2760 gggctgagga gccaggctat agcttaaaga ggctggggga gaaaagcttg gctgagacaa 2820 cccataggga gctagaggtt tttaatatat cctattctga ataagagacg aattcattca 2880 gatcagtggt ttcaaaccgt gctctgggca actcaattgc taagggttcc acaaacagga 2940 taaagtttct tatatacaaa aaaaaatgaa ggtttcaaat tacaccataa aacccctcat 3000 tgcttatgtc tacttggcag gtaaaattcc atttcaaaag ttaaatgtac ttaaaaaatt 3060 acctaagact gggtaaatta aaaaaattaa atgttgcaaa gaaaaaattc aaaattctta 3120 ttcttgaatg aaaaacgttc tcttactggt gattgaggag gagaaacaaa gactaacaaa 3180 tgaaaatggg agaatccaca ctcagagtgg ggcaattgaa caggcagggg cggatggatg 3240 gcagaggagg aggaatctgg actcaaggag ctagggggct ctgggcctgg aattttaggg 3300 tctggggccc aaggcaccag gagaagaggc aggtcaggat atctgagtca agacctggga 3360 tcttgcctta gcaatgacac tggagactaa aggtggactc catggtgccc ttgagcccag 3420 ccctacccca tctccactat cctctgccac cagctgtgca acttctgcta ggggtgaggt 3480 taataaactg gagaagttaa tttgtggagc atgaaacaga tgagcagaac aatcacagca 3540 ccttaatttc cccagtgtgc ccaagaacag agcaggcctg aagatactca aacagaaaca 3600 aacatgtgcc gtgtcactga taattctgtg tagacacaca cctgccagac actgctcatg 3660 gcactcccta ggaagaacag catgtgggaa aggctgccaa aattgttcat gtaaaaatta 3720 catcaatgct gtcttcctcg gtgctgccta tgcagctggc agccatctct tcctccacat 3780 catggcctcc ctcagactcc tcatgaagga taagatcctc aaaaagagga ccaacaagtt 3840 catgaggcac caatcagact gaaatgtcaa aattaagcat aactggcgga aacccagagg 3900 tcttaacagt agggttcgta gaaggtccaa gggccagatc ttgatgccca acattgctta 3960 tgggagcaac aacaacaaca aaaaaaacat gctgcccagt ggcttccaga agtttctggt 4020 ccacagcctc aaggagctga aagtgctgct gatgtgcaac aaatcttact gtgctgagat 4080 cgctcacaaa atttcctcca gaactgcaaa gtcatcatgg aaagagtcac ccagccggcc 4140 atcagagtca ccaaccccag taccagggtg cacagctaag aaaatgagta gaaagttcat 4200 gtccacgttt tgtgtgtaaa taaaaccata aaaactgcca aaaaaaatta catcaatgcc 4260 tctaaaccca aaggactcta cccccacagg tccctggttg ttgtggtgat tttcattgtg 4320 taaaatactt tccacatctt ttgacaccaa gtctttctgc agccatgttt gaaaattaac 4380 tttcaggcta cagagtcttt cttataccaa agttgaagaa agttttaaga aatatatttc 4440 tacatctcct acatgcaaaa caacaggagc aagttgagga attctcaaga aactggtcga 4500 gaagagagag cgcttagcta tggaaaagag aaagaaggaa gggagggctt cctggaggag 4560 gtggcatttg aaccaggact gacatcagga tggaaatgtc agtcagggag ttaagtaggg 4620 ggagcagctc cgccctccac gtccccagct cctcccgccc ctgttttttc tcccagtgac 4680 cccacgtgaa acgtctccgc ctcctccagc caccagcaga agggactgcc ttcccctcag 4740 tgctcgcccc tccctagtga tcactcagtg cccctgagct cattcttttc agtaaattct 4800 ctctctgcgt ggtgagaaaa caggcctgga gaggctctgc gacccgctta ggaccacaga 4860 actcggtact aggaaaactc ctattttaaa atccagccct gggtgggaag atttgggaag 4920 aatcgttaat attgagagag agagggagaa agaggattag atgagagtgg cgcctccgct 4980 catgtccgcc ccctccccgc agagaattac cttttccagg gacggcagga atgctacgcg 5040 tttaatggga cacagcgctt cctggagaga tacatctaca accgggagga gtacgcgcgc 5100 ttcgacagcg acgtggggga gttccgggcg gtgacggagc tggggcggcc tgctgcggag 5160 tactggaaca gccagaagga catcctggag gagaagcggg cagtgccgga caggatgtgc 5220 agacacaact acgagctggg cgggcccatg accctgcagc gccgaggtga gtgagggctt 5280 tgggccggcg gtcccagggc agccccgcgg gcccgtgccc agggcgcagg agcagccggg 5340 ttggcctaag ggaccttagt gccgggcgga aaggggactt tgggttgggg attcatgggg 5400 ggagcccatc tggagcttgt caggggagcg agcgcgggga cctggactgg gctgagcatg 5460 gagtgaggag gacgagagca gagagacccc cgggacttca tcaggcctgg cagctgactg 5520 catgtggggt gaaaaaagga agccacagga cagcgcacaa gggtatggtg tggagatgga 5580 ggtggagatg gcacagcagg ccacacagag aagaaaccta cagggaggta gctgggtttg 5640 aggtgcttga ggggcagatg ggtggtctga tgggcaggta gacagaaggg tctgcagccg 5700 gggaggagac tgagatacat gagaccatcc agggagaggg gacccagggg gaagagcaaa 5760 ggaccggatc ctgggaactg gacagttgtg atttggccaa gacagaaaag cctgtgaaag 5820 agaccaaaaa aacccaagtg cagtgtgagg agaggcccgc agagaagagt cttggaagct 5880 gaggggaggt gacctcagca gcacagtgga cagcggtgcc agtgacttgg gaaggtcaga 5940 aaacagaaga tggaaagtgg gtttggaaac cagggagacc tggggagagc aggttggccg 6000 cagcggcagg agctggaatg ggagggggtg catgaggctg agtgtggcgc atcctcctcg 6060 gggctgagat ggattttact tgtcttgggt tccccacggc tgtcacaggg cagtgtctca 6120 gttcattcgt ctttttcctt caggaagtct gggtgtaaag ggatggagag aggtgaggtg 6180 tgtgcagtaa gaggatttct caaggatggg acaggaaggc cttggagctt tggcttcctc 6240 ctgtgaactt gtggggtggg gagcctggtg caccaacctg agggacttga gggagtagta 6300 tcaggatgtg ggattgagcc ctggaccttt tttctagaaa gaggaaaaaa atgaagggag 6360 gaggaggagg aagctgggga gatcacacct ttgattttct tgttcctgga aagtgaaagg 6420 aagttcacct gctaggagtg agaaggtgga cacactgggt ggggatgagg tgagtgacat 6480 gagcttagga aagttgctga ggtaattggt tgagagaggt gttcaaataa aaataacgca 6540 attggcaaaa actgttacta agactttgta gaggcaccaa tcagtgacat ggcagcattt 6600 tctttcacag taatcaactg ccagattgca gacagccctg atgccagcct aaggagtgtg 6660 ggtttctcct ccaggcccgc aggtccccaa cctcactcct ctgaagactc ttctggagat 6720 cctctgtgat gcacagatct ccagactcag tgcccccaga ctcagattcc ctgggtgggg 6780 aggtctgggg atctctgctt gtaatcagct ccctagaggt tcccatgtag ccagataagt 6840 attgtcagaa cactgaagat ttttgaaaaa tgaaaaagag aaggttggag atgtgtcttc 6900 agaagactac taagggtgct ggctagagga gggaccagag gcagggagat gaggtaggaa 6960 actgctatta tttgtcaggg aaattgcaat caaggcatga gttagaacag ggaaaacaca 7020 gaggcaaggg agaggtggaa gggggaggaa agaagtagtg acaattccag ggtggatgtc 7080 cacccaaatc tagaagtaat tgagcaaatg ttttctgggc attagagaag gcaactagaa 7140 caaacaggaa tccttgcctt ggtgaaatgt atttgaactg ggtcagaaat gaggccattg 7200 ggtatcaggc cttaactcca gcgcaccctg gaggtcactg atgtggctcc aggctgacct 7260 gctcctgtca aagaatattg agcaagatgc ctctcgtgga atgttctggg accttaaaac 7320 agatacccaa gtattccccc tgatttcatg gttcccagaa gctctatggg gaagaaattg 7380 taggtaattc acaactgaga tttagacata agttgaatag tgtaatggac attgagttaa 7440 ccgaggtaat gaagtagtga gacacaggtg cccctgaaat aaactcacat tgagggaaga 7500 ggctgacaat gtggatcagt ctgaaaacaa ggcaaaaata caatagggag taagggttgt 7560 gtgtcagttc aagactgtac ttttacctgg cccagcgcca tgttagggta tttgtgttct 7620 ccaggaagta gaaaggaaag aactgagtga ttagggacct agaagactaa tttgagacat 7680 tcctcttgat gagctgttct ctagggtagt cctctgaaag agctgttctc tagtggatct 7740 ccctgaatga actgttctct aggagcactt gacccttttc tgtgtttgtt ttttgttttg 7800 tgtttgtgtt tgtttttgag acaggttctc actttgtctc ccaggctgga gtgctgtggc 7860 accatcatgg ctcactgcag cctcaacctc ctgggctcaa gtgatcctcc tgcctcagcc 7920 tcccatgtag ctagaactac agatacacgt accaccatgt ctggctaatt tatttttctt 7980 tttagagatg ggttctcact atgttgccca ggccggtctc aaaaccctgg gctcaagtga 8040 tcctcatgcc tcaacctccc aaagtgctaa gattataggc atgaccacca tgcctggcct 8100 tttctgcttt ctgaggagga aaaaggtact ggtggcagag atccaaaaga aaagttgcca 8160 gtggcagtgt ggaaattcac ctgagaacaa caggacaagc tggggcacaa atgcaaagat 8220 gcagagggag gcaacacctg gtcatctgtg agaccttcat gggacctgaa gacgcagcac 8280 agaggaggaa cttgaaaaag gacgggattt ctactactca agcatgtagg agctcaggat 8340 attctgtaaa tatgaagatt ttgagttttt gtaggtgagg taaaaaaata cataggtttt 8400 ttacagaata agacatgtaa agctctcttc attttctttg tattttcatg aagttattag 8460 attcacaggc caccataatg ccattgtctg tatatcttaa tttcaagata ttatttgagt 8520 aaattttgct tcctttgtat caagatagaa ctttgaaaag gtaggtaatt tcacagttga 8580 tcaaatattc tttgcccaaa ttacttttgg ttaaaatttc tcctaaatgt gctacagagt 8640 gcaaactctg tctccctgcc attccgctat atacttacta actattattt tattcaagat 8700 catgcatgct ctacttgaag gtctatttct atcttttcaa tgctaccctt acccactagc 8760 ctaatcacat tattcctatt ttcaacatct aggaatcaat tacatagtga acatgcctaa 8820 gaaataataa tctgggcaga tgcagtggct caggcccgta atcccagccc tttgagaggc 8880 cgagcgggtg gatcacttga ggtcaggcgt tggtcaagtg ctcctagaga accaggctga 8940 ccaacatgga gaaaccttgt ctctactaat aatacaaaaa ttagccaggt gaagtggcag 9000 gcacctataa tcccagctat tcgggaggct gaggaaggag aattggttga agcccggagg 9060 tggaggttgc agtgagccaa tattgcgcca ctgcattcca gacttggcaa cagagtgaca 9120 ctccatctca acaaaaagaa agaatgaaag aaagaaagag cgagattatg tctcaaaaaa 9180 aaggaaggaa ggaaggaagg aaggaaggaa ggaaggaagg aaggaaggaa ggaaggaaag 9240 aaggacaatc tcaaattcta tttcattatt tttcttccac gctcctagtc cagcctaggg 9300 tgaatgtttc cccctccaag aaggggccct tgcagcacca caacctgctt gtctgccacg 9360 tgacggattt ctacccaggc agcattcaag tccgatggtt cctgaatgga caggaggaaa 9420 cagctggggt cgtgtccacc aacctgatcc gtaatggaga ctggaccttc cagatcctgg 9480 tgatgctgga aatgaccccc cagcagggag atgtctacac ctgccaagtg gagcacacca 9540 gcctggatag tcctgtcacc gtggagtgga gtgagtctct gatgaccctc tagaccccac 9600 ctctgaagag caggggactc tctggctctg gggtccactc atcttatctt ctgcatctat 9660 accctggggc catgtccaaa ccccatcttt cttctatacc agctcctgag catagtttga 9720 agccagggaa atggagactt cctgaccttg gcttaggggt tcctgaagat tcatagttct 9780 cccccttgtc agagaatcta gggacactga ctggtctcga aaccctcaca cttaggaact 9840 gacctcacac ataggaacag ttctcttcct tcagcatttt agcctcttct caggcatttt 9900 gagaggcaac ttccagaatc agcatttgcc accttgttga ggtcacaccc ctgttccaga 9960 tatgagggtg gctctttctg aatttcctct tagcaagctt tttccgctgc actgtcctca 10020 tcccgatatg ctgcatcagg ctccagaatc tcagacagga catgagtagg gatgcagctg 10080 gtggaggtga cactaaacct gggtctgtcc ttcccagagg cacagtctga ttctgcccgg 10140 agtaagacat tgacgggagc tgggggcttc gtgctggggc tcatcatctg tggagtgggc 10200 atcttcatgc acaggaggag caagaaaggt gagaaagcct gcagggtgag cgggacttac 10260 cttcccctgg catattcaca cttattccac gatgaggggt ttgacagaaa agaaatgtca 10320 gaaagctcta gaggccactg atatcagata atcggggaac aaacatgacc tatagcgaga 10380 gagggatccc aggctgggat cttaatgcag ccagatgcat gaggtcccaa gtactcaggc 10440 tcctgcggag cgtccattga gtgatgggca atggaatttg gtgggatgga aatgtttctc 10500 taattatctg aggtggtttc aatggctgat tatataacct ttcgtctttc atttcagttc 10560 aacgaggatc tgcataaaca ggtaatattc ctgctttgat ttccttgtgg ggtgggttgc 10620 aggaggatat gagtcctttc tgtgcattgt aacactgagg ctcctccagg aagggaatct 10680 caggcatgaa cccctctttc aatgtcagcc ttcaggcaag tggggaaaga gcattgcttg 10740 gctccattgc tgaaggaagc agagatcaac tctgttattt atcagcctga gacgcatcct 10800 ctcaccataa tttttctctc ctggacttac aggaaggagg ctggcaacct gggataactt 10860 gtcttttacc cccacagggt tcctgagctc actgaaaaga ctattgtgcc ttaggaaaag 10920 catttgctgt gtttcgttag catctggctc caggacagac cttcaacttc caaattggat 10980 actgctgcca agaagttgct ctgaagtcag tttctatcat tctgctcttt gattcaaagc 11040 actgtttctc tcactgggcc tccaaccatg ttcccttctt cttagcacca caaataatca 11100 aaacccaaca tgactgtttg ttttccttta aaaatatgca ccaaatcatc tctcatcact 11160 tttctctgag ggttttagta gacagtagga gttaataaag aagttcattt tggtttaaac 11220 ataggaaaga agagaaccat gaaaatgggg atatgttaac tattgtataa tggggcctgt 11280 tacacatgac actcttctga attgactgta tttcagtgag ctgcccccaa atcaagttta 11340 gtgccctcat ccatttatgt ctcagaccac tattcttaac tattcaatgg tgagcagact 11400 gcaaatctgc ctgataggac ccatattccc acagcactaa ttcaacatat accttactga 11460 gagcatgttt tatcattacc attaagaagt taaatgaaca tcagaattta aaatcataaa 11520 tataatctaa tacactttaa 11540 //