Dbfetch
ID LR828246; SV 1; linear; genomic DNA; STD; HUM; 10749 BP. XX AC LR828246; XX PR Project:PRJEB39113; XX DT 23-JUL-2020 (Rel. 144, Created) DT 23-JUL-2020 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens, HLA-DRB1 gene for MHC class II antigen, cell line DE DKMS-LSL_ID15375641_DRB1_3, allele HLA-DRB1*15:new XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Albrecht V., Schmidt H. A., Klussmeier A., Lange V., Putke K.; RT ; RL Submitted (29-JUN-2020) to the INSDC. RL DKMS LIFE SCIENCE LAB, Research & Development, St. Petersburger Str. 2, RL Saxony, 01069 Dresden, Germany XX DR MD5; dee30c00d0ca431e7168b649777102de. XX FH Key Location/Qualifiers FH FT source 1..10749 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /cell_line="DKMS-LSL_ID15375641_DRB1_3" FT /db_xref="taxon:9606" FT exon 1..151 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=1 FT CDS join(52..151,5416..5685,7952..8233,8934..9044,9520..9543, FT 10685..10698) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAD0297776.1" FT /translation="MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECH FT FFNGTERVRFLDRYFYNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAV FT DTYCRHNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLN FT GQEEKAGMVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSE FT SAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS" FT intron 152..5415 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=1 FT exon 5416..5685 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=2 FT intron 5686..7951 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=2 FT exon 7952..8233 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=3 FT intron 8234..8933 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=3 FT exon 8934..9044 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=4 FT intron 9045..9519 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=4 FT exon 9520..9543 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=5 FT intron 9544..10684 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=5 FT exon 10685..10749 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=6 XX SQ Sequence 10749 BP; 2818 A; 2150 C; 2607 G; 3174 T; 0 other; gagtgagact tgcctgcttc tctggcccct ggtcctgtcc tgttctccag catggtgtgt 60 ctgaagctcc ctggaggctc ctgcatgaca gcgctgacag tgacactgat ggtgctgagc 120 tccccactgg ctttgtctgg ggacacccga cgtaagtgca cattgcgggt gctgagctac 180 tatggggtgg ggaaaatagg gagttttgtt aacattgtgc ccaggccatg tcccttaaga 240 aattgtgacg ttttcttcag agattgccca tctttatcat tggatcccaa attatttcct 300 ccataaaagg agcttgggta cttgccctct tcatgagact tgtgtaaggg gcctttgcac 360 aaatcatttc ttttcaaatc tccaccaata aaacctttgc atcacatgtc ctcagggtct 420 ttagaggatt tagaaataag gattctaaaa taaattcccc atacagcact tccctttatt 480 atgttgactt atgtcagaca aaaggaggtt cttactgaaa attttgtggg agtcaaggga 540 attcaaaggg tctctcctag acgatccagt gttaggttcc ccacaggacc tttggtgttg 600 gccatagtcc tcatatgtga ggatggaccc agtggcctcc ccattatctc ctttcttttc 660 ttgctgaact ccaatgttta taaggcctgt atccctgtag tgtatgtagg ttctctgaca 720 gaagttatac ttagtgctct tcctttcttg tggggaaaag tccctggaac tgaagctgag 780 attgttaata cttggagtca ccttacagat acagagcatt tatgaggtat tctttggtgc 840 ctaaagaact taaggcatcc tctgaaaaac tagcccaggt tcgtgttcat tatgaatctt 900 ttttaacctt tctgtacttg tttctcttgc atctcctatg tgctctaact agacatgaca 960 gaagagattt aactaatgta taaattatat gaaattctat tttttaagtc aaaaataatc 1020 aactatcaga aatttaataa tgttcaaact atatactctg tgtggggtta ccgagatgat 1080 gtgaacattg ttcacgtctc atagggctga aagtcaatgg gcaagtcttg ggaactcatt 1140 gtcttactgg ggtcttgtcc taaatttcct aggttcaccc atcatgccct cagctttcct 1200 taactagcca tgtctgctta cctcttcctc cagtttctat ttttccccag ctatgttgtc 1260 atcatttcca gaaatctcta aagcttgcac agaaccttag cactatgaga ttcattgaaa 1320 gagacttttt ttctcttttt gaggtagggc ctggctctgt cacccagtct atagctcagt 1380 ggtgtgatcg aggctcactg caacctctgc cacttatgct caagtgatcc tccctcctca 1440 ggctccagag tagctgggaa tacaggcagg caaccacgcc cagctaattt ttgtaatttt 1500 ggtagacatg agattttgcc atgttgccca ggctggtctt gaactgctgg actcaagcaa 1560 tcctcctgcc ttggcctccc aacatgctag gattatagat gtgagacact gtgcccaggc 1620 aaaagagatg actcttaata aaaaaatttc ctttttctta aatcactgtt tctttatctg 1680 tgaattcttc ttccaactag aaggaggaga aaaaagaagt ttgcctgtat ttatcactgg 1740 gaggagaagg ggtctagtgt gacattaaaa tgaaagagtg ctggagcttg agccccttct 1800 tgctttccag gatccctaca gtgatcagtt cccataccct ggtttattca tgtaaaccac 1860 acttattttt ctcagcagct actctttact gggctccatt ctaggttcaa atcattctat 1920 ttgattaagt tagagagcgt ccctactctc atggaagtta cacaagagta gaggagacag 1980 acactaaccc aataagcatt taacaaagaa gataatgtta gagagtcata gtgcactgaa 2040 gaaaagacat caggtttgtg aaaaagagag acatggattc acctacttta gttcatatgt 2100 tagggagctc cacctgagaa agtgacattc agctgagaca acaaaataag tagacagtcg 2160 tgaagatcta agggatgaaa gttccaggga gaccgaatcg ggggaaagcc ctgatgtgtt 2220 aaattatgtg gagggagaga aagaaagcta gaggggctga tgtatagaaa gcaaggaaat 2280 ggagaggcag aagatgaggg taggacacag agaggaattc aggagcctca tcattatagg 2340 ctctgatgtc cacagtaaaa aaaaattaaa ttttattatt tatttatttg tttgtttatt 2400 ttattttatt ttgtgatgga gtctctctct gttgcccagg ctagattgct gtggcacaat 2460 ctcggctcac tgcaacctcc gcctcctggg ttcaagcgat tctcctgcct cagcctcccg 2520 attagctggg gccacaggcg catgccacca cacctggcta attttttgta tttttagtag 2580 ggatagggtt tcaccgtgtt agccaggatg gtctcgatct cctgacctcg tgatccgccc 2640 gccttggcct cccaaagtgc tgggattaca ggcgtgagcc actgcgcccg gcctatattc 2700 aatgtttaaa actaattcta gctactctgt ggggattgga ttgttggggt tcactagtgg 2760 ttaggaagac tatttaggag cacagcaggg aattcttcag ggaaaacagg tttgtggctt 2820 catggagtgc attagtgata aagatggtga aaaagataaa gtggacagac ttggcatgta 2880 tttttgctta gcttgttaat gaattactgt aaagggggta gaacaatcaa gcttattcct 2940 aaggattttc ttttgacaaa taaatgggtg gtagtgttgt ttattgagat aggaaaaact 3000 atgggaggaa atgatttgaa gtgggtggtt tgaaataaaa gttttgttta aatatgagat 3060 gattgattga catttatgtg gagaaatccg aaggtcaatg gcatttaaga gactcatggt 3120 gaggccaggg cttcaggtat ttatgttggc agcagcaata cgtgtagtgt gttaaattcc 3180 agggcgtgga agaggataca tagggagatg gattgtgtga agaaaaaaga acagggcaca 3240 ggccagcaaa gggggctgag aaagagccca aggatgctgg agaaaaacca agagaacatc 3300 atgtgtgtaa gtccaggaaa atagattatt ttcaaggaga agggagaggc caattgtggt 3360 gagtaccact aagaggaggg gcaagtgaga atatgataga gaagcaagtg ctgggtttgg 3420 tggagtcgat atttgcagtc aatggagcat ccaggtagga aactggattg gaccatttga 3480 agagtgagta aaagtgagga cgaggttaag gttgactgtt ttgagtagag agcttcaggg 3540 aaggattgtt ctctgggttc agggagccag ctgaacctaa aggaaaaggc taaagaagct 3600 gaagagaagg aggaggacct gtgaaccaga gatgctcagt cattattagc gaggaaatac 3660 ggagagcccc tgtgtgcagt ggtgactact catgcaaaat gtcacacagc caatatttaa 3720 cacagccagt atttcacaca gccaatattt attagtgaca tagcatatac cagttattac 3780 tctaggtcat gagaatggag tgataaataa aatgaatcca gtcgccatca ctatatgcca 3840 tgtaacattt tgcaatgact gtgtatcagg cctatgaatt tcagtattca atttcaataa 3900 tgatcctgtt gtatctgtgg tatttaaaaa catatacatc tctggaatct aaaattgaga 3960 ggttataagt aacacccagt attacaaatt tagtgctgga aatcagattg cagtttaaat 4020 ctgagcatat agaaagtccg tttcttctat gtcagcagat gctttttgtg tgaggtttag 4080 gtatactgca ttatttgaca taaaccagtg tttctgccct atgtcttcag aatgacaatt 4140 ctttatgaaa ctaatagaag aacagaagac aattgcaaaa tcatgatgaa gatactaatt 4200 gctttagaat taaggaatac aaaaaataat atgagctgca gttataggat cagaaaagtt 4260 aaaatgggaa tgtattcgag tgtttattat gtgatcagtg ctaagaagtg tcatcattta 4320 attttacact taacggtaat cctgtgagga ttacgctatt attaaatgca tttgatagat 4380 tacaaaaagg cttatggttg gtaaaaattg acccaagtag aagagatcgt gtttttattc 4440 aggttttctg attatagagt ttgagagttt gaccatcatt agtgagtagt gactatattg 4500 tgtctgaatt attgacacaa tttctgatat tcatatgtac caggctgttt cttagagtgg 4560 ggacagaaat gcaagggctg ctagttctga tgtataggag aaactttcat tcattttgca 4620 tttatcattt taaacgttgt atatgtctat ctgggcatgt gttcaagaac acaaggaagt 4680 attaaatcac tccttcttct gaggtttgac tagcaagttg ggctagagtt acaaataaaa 4740 tacaggttcc tagtgaaatc tgaatttcag atacacaacc ataatttatt ggaaatccaa 4800 atttaactgg gaatcttcta ttattctctg ctctagaacg ccacacttct gatatttctc 4860 attgctgtct aagctcttgt gtgtttggtt tttggccatc gctttcactg ctctttaagc 4920 tcccccagag gagtggagag gtctgttttc cctcgtttgg attcctagag gcagcgcagg 4980 cctggcacaa ggtcatcact aaggaagtgt tcacagggtg aacgcggtgg gtgctgttga 5040 aggtaccggt aaagcgtgtg ggatgagagg agcagagagt gtctttgggg ctcccaggag 5100 gaggcggcgc gggctgcggt gctgggcgga tcctcctcca gctcctgctt ggaggtctcc 5160 agaacaggct ggaggcaggg agggggtccc aaaagcctgg ggatgagaag gggttttccc 5220 gcatggtccc ccaggccccc gttcgcctca ggaagacgga ggatgagctc ctgggctgca 5280 ggtggtgggc gttgcgggtg gggccggtta aggttccagc gcccgcaccc cgctcaggga 5340 gccccggatg gtggcgtcgc tgtccgtgtc ttctcaggag gccgccctgt gaccggatgg 5400 ttcgtgtccc cacagcacgt ttcctgtggc agcctaagag ggagtgtcat ttcttcaatg 5460 ggacggagcg ggtgcggttc ctggacagat acttctataa ccaggaggag tccgtgcgct 5520 tcgacagcga cgtgggggag ttccgggcgg tgacggagct ggggcggcct gacgctgagt 5580 actggaacag ccagaaggac atcctggagc aggcgcgggc cgcggtggac acctactgca 5640 gacacaacta cggggttgtg gagagcttca cagtgcagcg gcgaggtgag catggccgcg 5700 ggcggggcct gagtccccgt gagctgggaa tctgagtgtg tgtgtgtgtg tgtgtgtgtg 5760 tgtgtgtgtg tgagagagag acagagagag acagagagag gaagagagag agagagcgcc 5820 atctgtgagc atttagaatc ctctcagtcc ggagcaagca gttctgagag cacaggtgtg 5880 tgtgtaaagt gtggatttgt ctgtgtctgt gtgtctgttg tgggagggga ggcaggaggg 5940 ggctgtttct tatccttgga gacctctgtg gggaggtgac aagggaggtg ggtgctgggg 6000 gctggagaga gaggagacct tgattatctc ggtccttaga gatgcaggga agggaaatgt 6060 aaggtgtgtg tggttggggt gaaggtttag gggaggactg ctgaggggta aggcaggttt 6120 gggataatgt gaggaggcca gttccagact ctccctggca tacacccttc gtgtaatctc 6180 tgaattaaaa gtgtgtgctg tttgtttgta aaagcaatag attaatttct agaggaactg 6240 agtagacctc tgaggcacct ctgaagcttc tttagatcta aatttcttcc tagttttttg 6300 tttttttcag tgtgtatatt tttacatagt agaaatgact gtgaaactaa ctttttgaat 6360 taaagttttg acacggttac tattttatta taatgctggt agttttctag tagttacata 6420 ttattctttt atatataata tttgtgacac aactcacctc actttcccgt ttgttgacct 6480 ttattatgac attcaccaga agttgaaatt gtgtgtttct ggttaatttt taatttatat 6540 tttttatttg taattccttt gaattatttt gccctattta ttggccgatt ataattattg 6600 ctctaagaat tccctattgt atttggtagg taatggacaa tgatctacgg tctaatatct 6660 tgagggctta gtatttttct cagtgacttt ctgcgttctt tgtactataa gattattaac 6720 actttattga tatttgatcc agcatttgct ccagtttgtg gtttgtatgt ggattttgaa 6780 aattcttttc catgttaaga atttgaacat ttttatttaa taaaatatat tgcaacattt 6840 ttattaatga tctacaatcc atctgaaatc tgccattttg tggcattgtt gtctccaggt 6900 ttctccttac ttctaaaaaa atagttgtat ttattgagag tatgctagtg tcggggattt 6960 tcctgggcat aagcacccca agtaacgagt cccagacact gccttaatcc aaatgtgatt 7020 ctggaaagaa aaatcatttt acaatgatag gcctaataat aattatgctt gtgttgcacg 7080 ggagatgcat tgatcagcta aatgtaaata taagaacttt caaaacttaa atgacgttcc 7140 ctaatccttc tctctgcttc aggactcatg cttttctagg aaagtaaaaa tttggagaat 7200 catttctgtc tgtcccacct tcccaggggc agaacaattt ctgttgtgtt ctaaggtgtg 7260 agtgcatggg agtagtattc ctaaaattca tacttggttt cctcatgtac ccaactctgt 7320 ccctttatct atgcatattg ctttaaatca tatttttctg tcaaggtgta caaggatgat 7380 aaataggtgc caagtggagc actcaagtgt gatgagtgcc ctcacagtgg aatggagtga 7440 gaagctttct gacctcataa actgaaggct atcttcagtc attgttttat atattttacg 7500 tgcattaatc ctcatataac cccaagaggt aaattagtat aattatcctt cattgtaggt 7560 gacaaagttg agacacagaa gaatcaaaaa actcttccag gatcaaccag taaaaggcag 7620 accttggatt cgaaccaggc aacctggctc aaatatcagt tttaattact acactctgta 7680 ctttccaaga tttgtaaaca gtttgacaat gcatgccgat ttaaaactat gaagaaacaa 7740 acacaatttt tcacaacacc tctcaaatct aatgggtcct cactgtcaag attaaattcc 7800 aggctgatga cactgtaagg tcacatggcc agctgtgcta taggcctggt caaggccaga 7860 gcctgggttt gcagagaagc agacacacag ccaaaccagg agacttactc tgtcttcctg 7920 actcattccc tctacgttgt ttttctccta gtccaaccta aggtgactgt atatccttca 7980 aagacccagc ccctgcagca ccacaacctc ctggtctgct ctgtgagtgg tttctatcca 8040 ggcagcattg aagtcaggtg gttcctgaat ggccaggaag agaaggctgg gatggtgtcc 8100 acaggcctga tccagaatgg agactggacc ttccagaccc tggtgatgct ggaaacagtt 8160 cctcgaagtg gagaggttta cacctgccaa gtggagcacc caagcgtgac aagccctctc 8220 acagtggaat ggagtgagca gctttctgac ttcctaaatt tctcacccac taagaagggg 8280 accgtgctaa tccctgagtg tcaggttcct cctctcccac atcctatttt aatttgctcc 8340 atgttctcat ctccatcagc acaggtcact gggggtagcc ctgtaggtgt ttctagaaac 8400 acctgtacct cctggagaag cagtctcgcc tgccaggcgg gagagactgt ccctcttttg 8460 aacctcccca tgattttgca ggtcagggtc acccactctc ccaggctcca ggccctgcct 8520 ctgggtctga gactgagttt ctggtgctgt tgctctgagt tattttttgt gatctgggaa 8580 gaggagaagt gtaggggcct acctgacatg aggggagtcc aatctcagcc ctgcttttta 8640 ttagctttgt cactctagac aaactactta tcctcattga gtctcaggct ttctgtggat 8700 cagatgttga acttgtgcct tacatcaagg ctgtaatatt tgaatgagtt tgatgtctga 8760 acgtcgtaac tgttcagtgt aatttgaaat cctttttttc tcctgaaatg gctagttatt 8820 ttagttcttg tgaggcagct ttctgcccca ttttcaaagc tctaaatctt agagtctcaa 8880 gtaaaaaggt tcaatttgga ataaacatca ctaaacctgg cttcctctct caggagcacg 8940 gtctgaatct gcacagagca agatgctgag tggagtcggg ggctttgtgc tgggcctgct 9000 cttccttggg gccgggctgt tcatctactt caggaatcag aaaggtgagg agcctttggg 9060 agctggctct ctccataggc ttttctggag gaggaactat ggctttgctg aggttagttc 9120 tcagtatatg agtggccctg aataaagcct ttctttcccc aaacggctct aatgtcctgc 9180 taatccagaa atcatcagtg catggttact atgtgaaagc ataatagctt gtggcctgca 9240 gagacgagag gaaggttaac aagtaggggt cctttggttt gagatcctgg agcaaattaa 9300 ggaagagcca ctaaggctaa tggaattaca ctggatcctg tgacagacac ttcaggcttc 9360 atgggtcaca tggtctgttt ctgctccttt ctgccctggt tggtgtgggt tgtggtgtta 9420 gagaaatctc aggtgggaga tctggggctg ggacattgtg ttggaggaca gatttgcttc 9480 aataactttt aagtgtatat cttttcctct ttttcccagg acactctgga cttcagccaa 9540 caggtaatac cttttaatcc tcttttagaa acagacacag tttccctagt gagaggtgaa 9600 gccagctgga cttctgggtg gggtggggac ttggagaact tttcttacaa gaggtttttt 9660 tttgtttttt tttttttttt ttttttgaga cggagtctcg ctctgtcgcc caggctggag 9720 tgcagtggcg ggatctcggc tcactgcaag ctccgcctcc cgggttcacg ccattctcct 9780 gcctcagcct cccaagtagc tgggactaca ggcgcccgcc actacgcccg gctaattttt 9840 tgtattttta gtagagacgg ggtttcaccg ttttagccag gatggtctcg atctcctgac 9900 ctcgtgatcc gcccgcctcg gcctcccaaa gtgctgggat tacaggcgtg agccaccgcg 9960 cccggcctac aagaggtttc taaatgcacc aatcagtgct ttgtaaaaac acaccaatag 10020 gttctctgtg gctagctgga tgtttgtaaa atggaccaat tcgcactctg taaaatagac 10080 caatcagcac tctttaaaat ggaccaatca gcacttttaa aatgggccaa tcaccactct 10140 ttaaaatgga ccaatcagca ctctttaaaa tggaccaatc tgcaggacat gggcagggac 10200 aaatacagga ataaaagctg gccaccccaa ccagcagtgg caacccactc aggtcctctt 10260 ccctgctgtg gaagttttgt tcttttgatc ttcacaataa atcttgctgc tgcccactct 10320 ttggatccct gccgccttta agagctgtaa cactcactgt gaaggtctgc aggaagtcag 10380 cgagaccaca aacccaccgg aaggaacaaa ctcaggacac accagaatga tggtagaggt 10440 gataaggcat gagacagaaa taataggaaa gactttggat ccaaatttct gatcaggcaa 10500 tttacaccaa aattcctcct ctccacttag aaaaggtgtg ctctgcggga ctattggctc 10560 aggggagact caggaacttc tttttcttct tcctgcagtg ctctcatctg agcccttgaa 10620 agaggggaaa agaaactgtt agtagagcca ggttgaaaac aacactctcc tctgtctttt 10680 gcaggattcc tgagctgaaa tgcagatgac cacattcaag gaagaacttt ctgccccggc 10740 tttgcagga 10749 //