Dbfetch
ID LR828227; SV 1; linear; genomic DNA; STD; HUM; 10898 BP. XX AC LR828227; XX PR Project:PRJEB39113; XX DT 23-JUL-2020 (Rel. 144, Created) DT 23-JUL-2020 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens, HLA-DRB1 gene for MHC class II antigen, cell line DE DKMS-LSL_ID16017833_DRB1_3, allele HLA-DRB1*15:new XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Albrecht V., Schmidt H. A., Klussmeier A., Lange V., Putke K.; RT ; RL Submitted (29-JUN-2020) to the INSDC. RL DKMS LIFE SCIENCE LAB, Research & Development, St. Petersburger Str. 2, RL Saxony, 01069 Dresden, Germany XX DR MD5; 02c15530fea2ebe13806ca9c3fe816ed. XX FH Key Location/Qualifiers FH FT source 1..10898 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /cell_line="DKMS-LSL_ID16017833_DRB1_3" FT /db_xref="taxon:9606" FT exon 1..151 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=1 FT CDS join(52..151,5416..5685,7950..8231,8932..9042,9518..9541, FT 10684..10697) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAD0297757.1" FT /translation="MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECH FT FFNGTERVRFLDRYFYNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAV FT DTYCRHNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLN FT GQEEKAGMVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSE FT SAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS" FT intron 152..5415 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=1 FT exon 5416..5685 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=2 FT intron 5686..7949 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=2 FT exon 7950..8231 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=3 FT intron 8232..8931 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=3 FT exon 8932..9042 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=4 FT intron 9043..9517 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=4 FT exon 9518..9541 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=5 FT intron 9542..10683 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=5 FT exon 10684..10898 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*15:new" FT /number=6 XX SQ Sequence 10898 BP; 2847 A; 2193 C; 2642 G; 3216 T; 0 other; gagtgagact tgcctgcttc tctggcccct ggtcctgtcc tgttctccag catggtgtgt 60 ctgaagctcc ctggaggctc ctgcatgaca gcgctgacag tgacactgat ggtgctgagc 120 tccccactgg ctttgtctgg ggacacccga cgtaagtgca cattgcgggt gctgagctac 180 tatggggtgg ggaaaatagg gagttttgtt aacattgtgc ccaggccatg tcccttaaga 240 aattgtgacg ttttcttcag agattgccca tctttatcat tggatcccaa attatttcct 300 ccataaaagg agcttgggta cttgccctct tcatgagact tgtgtaaggg gcctttgcac 360 aaatcatttc ttttcaaatc tccaccaata aaacctttgc atcacatgtc ctcagggtct 420 ttagaggatt tagaaataag gattctaaaa taaattcccc atacagcact tccctttatt 480 atgttgactt atgtcagaca aaaggaggtt cttactgaaa attttgtggg agtcaaggga 540 attcaaaggg tctctcctag acgatccagt gttaggttcc ccacaggacc tttggtgttg 600 gccatagtcc tcatatgtga ggatggaccc agtggcctcc ccattatctc ctttcttttc 660 ttgctgaact ccaatgttta taaggcctgt atccctgtag tgtatgtagg ttctctgaca 720 gaagttatac ttagtgctct tcctttcttg tggggaaaag tccctggaac tgaagctgag 780 attgttaata cttggagtca ccttacagat acagagcatt tatgaggtat tctttggtgc 840 ctaaagaact taaggcatcc tctgaaaaac tagcccaggt tcgtgttcat tatgaatctt 900 ttttaacctt tctgtacttg tttctcttgc atctcctatg tgctctaact agacatgaca 960 gaagagattt aactaatgta taaattatat gaaattctat tttttaagtc aaaaataatc 1020 aactatcaga aatttaataa tgttcaaact atatactctg tgtggggtta ccgagatgat 1080 gtgaacattg ttcacgtctc atagggctga aagtcaatgg gcaagtcttg ggaactcatt 1140 gtcttactgg ggtcttgtcc taaatttcct aggttcaccc atcatgccct cagctttcct 1200 taactagcca tgtctgctta cctcttcctc cagtttctat ttttccccag ctatgttgtc 1260 atcatttcca gaaatctcta aagcttgcac agaaccttag cactatgaga ttcattgaaa 1320 gagacttttt ttctcttttt gaggtagggc ctggctctgt cacccagtct atagctcagt 1380 ggtgtgatcg aggctcactg caacctctgc cacttatgct caagtgatcc tccctcctca 1440 ggctccagag tagctgggaa tacaggcagg caaccacgcc cagctaattt ttgtaatttt 1500 ggtagacatg agattttgcc atgttgccca ggctggtctt gaactgctgg actcaagcaa 1560 tcctcctgcc ttggcctccc aacatgctag gattatagat gtgagacact gtgcccaggc 1620 aaaagagatg actcttaata aaaaaatttc ctttttctta aatcactgtt tctttatctg 1680 tgaattcttc ttccaactag aaggaggaga aaaaagaagt ttgcctgtat ttatcactgg 1740 gaggagaagg ggtctagtgt gacattaaaa tgaaagagtg ctggagcttg agccccttct 1800 tgctttccag gatccctaca gtgatcagtt cccataccct ggtttattca tgtaaaccac 1860 acttattttt ctcagcagct actctttact gggctccatt ctaggttcaa atcattctat 1920 ttgattaagt tagagagcgt ccctactctc atggaagtta cacaagagta gaggagacag 1980 acactaaccc aataagcatt taacaaagaa gataatgtta gagagtcata gtgcactgaa 2040 gaaaagacat caggtttgtg aaaaagagag acatggattc acctacttta gttcatatgt 2100 tagggagctc cacctgagaa agtgacattc agctgagaca acaaaataag tagacagtcg 2160 tgaagatcta agggatgaaa gttccaggga gaccgaatcg ggggaaagcc ctgatgtgtt 2220 aaattatgtg gagggagaga aagaaagcta gaggggctga tgtatagaaa gcaaggaaat 2280 ggagaggcag aagatgaggg taggacacag agaggaattc aggagcctca tcattatagg 2340 ctctgatgtc cacagtaaaa aaaaattaaa ttttattatt tatttatttg tttgtttatt 2400 ttattttatt ttgtgatgga gtctctctct gttgcccagg ctagattgct gtggcacaat 2460 ctcggctcac tgcaacctcc gcctcctggg ttcaagcgat tctcctgcct cagcctcccg 2520 attagctggg gccacaggcg catgccacca cacctggcta attttttgta tttttagtag 2580 ggatagggtt tcaccgtgtt agccaggatg gtctcgatct cctgacctcg tgatccgccc 2640 gccttggcct cccaaagtgc tgggattaca ggcgtgagcc actgcgcccg gcctatattc 2700 aatgtttaaa actaattcta gctactctgt ggggattgga ttgttggggt tcactagtgg 2760 ttaggaagac tatttaggag cacagcaggg aattcttcag ggaaaacagg tttgtggctt 2820 catggagtgc attagtgata aagatggtga aaaagataaa gtggacagac ttggcatgta 2880 tttttgctta gcttgttaat gaattactgt aaagggggta gaacaatcaa gcttattcct 2940 aaggattttc ttttgacaaa taaatgggtg gtagtgttgt ttattgagat aggaaaaact 3000 atgggaggaa atgatttgaa gtgggtggtt tgaaataaaa gttttgttta aatatgagat 3060 gattgattga catttatgtg gagaaatccg aaggtcaatg gcatttaaga gactcatggt 3120 gaggccaggg cttcaggtat ttatgttggc agcagcaata cgtgtagtgt gttaaattcc 3180 agggcgtgga agaggataca tagggagatg gattgtgtga agaaaaaaga acagggcaca 3240 ggccagcaaa gggggctgag aaagagccca aggatgctgg agaaaaacca agagaacatc 3300 atgtgtgtaa gtccaggaaa atagattatt ttcaaggaga agggagaggc caattgtggt 3360 gagtaccact aagaggaggg gcaagtgaga atatgataga gaagcaagtg ctgggtttgg 3420 tggagtcgat atttgcagtc aatggagcat ccaggtagga aactggattg gaccatttga 3480 agagtgagta aaagtgagga cgaggttaag gttgactgtt ttgagtagag agcttcaggg 3540 aaggattgtt ctctgggttc agggagccag ctgaacctaa aggaaaaggc taaagaagct 3600 gaagagaagg aggaggacct gtgaaccaga gatgctcagt cattattagc gaggaaatac 3660 ggagagcccc tgtgtgcagt ggtgactact catgcaaaat gtcacacagc caatatttaa 3720 cacagccagt atttcacaca gccaatattt attagtgaca tagcatatac cagttattac 3780 tctaggtcat gagaatggag tgataaataa aatgaatcca gtcgccatca ctatatgcca 3840 tgtaacattt tgcaatgact gtgtatcagg cctatgaatt tcagtattca atttcaataa 3900 tgatcctgtt gtatctgtgg tatttaaaaa catatacatc tctggaatct aaaattgaga 3960 ggttataagt aacacccagt attacaaatt tagtgctgga aatcagattg cagtttaaat 4020 ctgagcatat agaaagtccg tttcttctat gtcagcagat gctttttgtg tgaggtttag 4080 gtatactgca ttatttgaca taaaccagtg tttctgccct atgtcttcag aatgacaatt 4140 ctttatgaaa ctaatagaag aacagaagac aattgcaaaa tcatgatgaa gatactaatt 4200 gctttagaat taaggaatac aaaaaataat atgagctgca gttataggat cagaaaagtt 4260 aaaatgggaa tgtattcgag tgtttattat gtgatcagtg ctaagaagtg tcatcattta 4320 attttacact taacggtaat cctgtgagga ttacgctatt attaaatgca tttgatagat 4380 tacaaaaagg cttatggttg gtaaaaattg acccaagtag aagagatcgt gtttttattc 4440 aggttttctg attatagagt ttgagagttt gaccatcatt agtgagtagt gactatattg 4500 tgtctgaatt attgacacaa tttctgatat tcatatgtac caggctgttt cttagagtgg 4560 ggacagaaat gcaagggctg ctagttctga tgtataggag aaactttcat tcattttgca 4620 tttatcattt taaacgttgt atatgtctat ctgggcatgt gttcaagaac acaaggaagt 4680 attaaatcac tccttcttct gaggtttgac tagcaagttg ggctagagtt acaaataaaa 4740 tacaggttcc tagtgaaatc tgaatttcag atacacaacc ataatttatt ggaaatccaa 4800 atttaactgg gaatcttcta ttattctctg ctctagaacg ccacacttct gatatttctc 4860 attgctgtct aagctcttgt gtgtttggtt tttggccatc gctttcactg ctctttaagc 4920 tcccccagag gagtggagag gtctgttttc cctcgtttgg attcctagag gcagcgcagg 4980 cctggcacaa ggtcatcact aaggaagtgt tcacagggtg aacgcggtgg gtgctgttga 5040 aggtaccggt aaagcgtgtg ggatgagagg agcagagagt gtctttgggg ctcccaggag 5100 gaggcggcgc gggctgcggt gctgggcgga tcctcctcca gctcctgctt ggaggtctcc 5160 agaacaggct ggaggcaggg agggggtccc aaaagcctgg ggatgagaag gggttttccc 5220 gcatggtccc ccaggccccc gttcgcctca ggaagacgga ggatgagctc ctgggctgca 5280 ggtggtgggc gttgcgggtg gggccggtta aggttccagc gcccgcaccc cgctcaggga 5340 gccccggatg gtggcgtcgc tgtccgtgtc ttctcaggag gccgccctgt gaccggatgg 5400 ttcgtgtccc cacagcacgt ttcctgtggc agcctaagag ggagtgtcat ttcttcaatg 5460 ggacggagcg ggtgcggttc ctggacagat acttctataa ccaggaggag tccgtgcgct 5520 tcgacagcga cgtgggggag ttccgggcgg tgacggagct ggggcggcct gacgctgagt 5580 actggaacag ccagaaggac atcctggagc aggcgcgggc cgcggtggac acctactgca 5640 gacacaacta cggagttgtg gagagcttca cagtgcagcg gcgaggtgag catggccgcg 5700 ggcggggcct gagtccccgt gagctgggaa tctgagtgtg tgtgtgtgtg tgtgtgtgtg 5760 tgtgtgtgtg agagagagac agagagagac agagagagga agagagagag agagcgccat 5820 ctgtgagcat ttagaatcct ctcagtccgg agcaagcagt tctgagagca caggtgtgtg 5880 tgtaaagtgt ggatttgtct gtgtctgtgt gtctgttgtg ggaggggagg caggaggggg 5940 ctgtttctta tccttggaga cctctgtggg gaggtgacaa gggaggtggg tgctgggggc 6000 tggagagaga ggagaccttg attatctcgg tccttagaga tgcagggaag ggaaatgtaa 6060 ggtgtgtgtg gttggggtga aggtttaggg gaggactgct gaggggtaag gcaggtttgg 6120 gataatgtga ggaggccagt tccagactct ccctggcata cacccttcgt gtaatctctg 6180 aattaaaagt gtgtgctgtt tgtttgtaaa agcaatagat taatttctag aggaactgag 6240 tagacctctg aggcacctct gaagcttctt tagatctaaa tttcttccta gttttttgtt 6300 tttttcagtg tgtatatttt tacatagtag aaatgactgt gaaactaact ttttgaatta 6360 aagttttgac acggttacta ttttattata atgctggtag ttttctagta gttacatatt 6420 attcttttat atataatatt tgtgacacaa ctcacctcac tttcccgttt gttgaccttt 6480 attatgacat tcaccagaag ttgaaattgt gtgtttctgg ttaattttta atttatattt 6540 tttatttgta attcctttga attattttgc cctatttatt ggccgattat aattattgct 6600 ctaagaattc cctattgtat ttggtaggta atggacaatg atctacggtc taatatcttg 6660 agggcttagt atttttctca gtgactttct gcgttctttg tactataaga ttattaacac 6720 tttattgata tttgatccag catttgctcc agtttgtggt ttgtatgtgg attttgaaaa 6780 ttcttttcca tgttaagaat ttgaacattt ttatttaata aaatatattg caacattttt 6840 attaatgatc tacaatccat ctgaaatctg ccattttgtg gcattgttgt ctccaggttt 6900 ctccttactt ctaaaaaaat agttgtattt attgagagta tgctagtgtc ggggattttc 6960 ctgggcataa gcaccccaag taacgagtcc cagacactgc cttaatccaa atgtgattct 7020 ggaaagaaaa atcattttac aatgataggc ctaataataa ttatgcttgt gttgcacggg 7080 agatgcattg atcagctaaa tgtaaatata agaactttca aaacttaaat gacgttccct 7140 aatccttctc tctgcttcag gactcatgct tttctaggaa agtaaaaatt tggagaatca 7200 tttctgtctg tcccaccttc ccaggggcag aacaatttct gttgtgttct aaggtgtgag 7260 tgcatgggag tagtattcct aaaattcata cttggtttcc tcatgtaccc aactctgtcc 7320 ctttatctat gcatattgct ttaaatcata tttttctgtc aaggtgtaca aggatgataa 7380 ataggtgcca agtggagcac tcaagtgtga tgagtgccct cacagtggaa tggagtgaga 7440 agctttctga cctcataaac tgaaggctat cttcagtcat tgttttatat attttacgtg 7500 cattaatcct catataaccc caagaggtaa attagtataa ttatccttca ttgtaggtga 7560 caaagttgag acacagaaga atcaaaaaac tcttccagga tcaaccagta aaaggcagac 7620 cttggattcg aaccaggcaa cctggctcaa atatcagttt taattactac actctgtact 7680 ttccaagatt tgtaaacagt ttgacaatgc atgccgattt aaaactatga agaaacaaac 7740 acaatttttc acaacacctc tcaaatctaa tgggtcctca ctgtcaagat taaattccag 7800 gctgatgaca ctgtaaggtc acatggccag ctgtgctata ggcctggtca aggccagagc 7860 ctgggtttgc agagaagcag acacacagcc aaaccaggag acttactctg tcttcctgac 7920 tcattccctc tacgttgttt ttctcctagt ccaacctaag gtgactgtat atccttcaaa 7980 gacccagccc ctgcagcacc acaacctcct ggtctgctct gtgagtggtt tctatccagg 8040 cagcattgaa gtcaggtggt tcctgaacgg ccaggaagag aaggctggga tggtgtccac 8100 aggcctgatc cagaatggag actggacctt ccagaccctg gtgatgctgg aaacagttcc 8160 tcgaagtgga gaggtttaca cctgccaagt ggagcaccca agcgtgacaa gccctctcac 8220 agtggaatgg agtgagcagc tttctgactt cctaaatttc tcacccacta agaaggggac 8280 cgtgctaatc cctgagtgtc aggttcctcc tctcccacat cctattttaa tttgctccat 8340 gttctcatct ccatcagcac aggtcactgg gggtagccct gtaggtgttt ctagaaacac 8400 ctgtacctcc tggagaagca gtctcgcctg ccaggcggga gagactgtcc ctcttttgaa 8460 cctccccatg attttgcagg tcagggtcac ccactctccc aggctccagg ccctgcctct 8520 gggtctgaga ctgagtttct ggtgctgttg ctctgagtta ttttttgtga tctgggaaga 8580 ggagaagtgt aggggcctac ctgacatgag gggagtccaa tctcagccct gctttttatt 8640 agctttgtca ctctagacaa actacttatc ctcattgagt ctcaggcttt ctgtggatca 8700 gatgttgaac ttgtgcctta catcaaggct gtaatatttg aatgagtttg atgtctgaac 8760 gtcgtaactg ttcagtgtaa tttgaaatcc tttttttctc ctgaaatggc tagttatttt 8820 agttcttgtg aggcagcttt ctgccccatt ttcaaagctc taaatcttag agtctcaagt 8880 aaaaaggttc aatttggaat aaacatcact aaacctggct tcctctctca ggagcacggt 8940 ctgaatctgc acagagcaag atgctgagtg gagtcggggg ctttgtgctg ggcctgctct 9000 tccttggggc cgggctgttc atctacttca ggaatcagaa aggtgaggag cctttgggag 9060 ctggctctct ccataggctt ttctggagga ggaactatgg ctttgctgag gttagttctc 9120 agtatatgag tggccctgaa taaagccttt ctttccccaa acggctctaa tgtcctgcta 9180 atccagaaat catcagtgca tggttactat gtgaaagcat aatagcttgt ggcctgcaga 9240 gacgagagga aggttaacaa gtaggggtcc tttggtttga gatcctggag caaattaagg 9300 aagagccact aaggctaatg gaattacact ggatcctgtg acagacactt caggcttcat 9360 gggtcacatg gtctgtttct gctcctttct gccctggttg gtgtgggttg tggtgttaga 9420 gaaatctcag gtgggagatc tggggctggg acattgtgtt ggaggacaga tttgcttcaa 9480 taacttttaa gtgtatatct tttcctcttt ttcccaggac actctggact tcagccaaca 9540 ggtaatacct tttaatcctc ttttagaaac agacacagtt tccctagtga gaggtgaagc 9600 cagctggact tctgggtggg gtggggactt ggagaacttt tcttacaaga ggtttttttt 9660 tgtttttttt tttttttttt tttttgagac ggagtctcgc tctgtcgccc aggctggagt 9720 gcagtggcgg gatctcggct cactgcaagc tccgcctccc gggttcacgc cattctcctg 9780 cctcagcctc ccaagtagct gggactacag gcgcccgcca ctacgcccgg ctaatttttt 9840 gtatttttag tagagacggg gtttcaccgt tttagccagg atggtctcga tctcctgacc 9900 tcgtgatccg cccgcctcgg cctcccaaag tgctgggatt acaggcgtga gccaccgcgc 9960 ccggcctaca agaggtttct aaatgcacca atcagtgctt tgtaaaaaca caccaatagg 10020 ttctctgtgg ctagctggat gtttgtaaaa tggaccaatt cgcactctgt aaaatagacc 10080 aatcagcact ctttaaaatg gaccaatcag cacttttaaa atgggccaat caccactctt 10140 taaaatggac caatcagcac tctttaaaat ggaccaatct gcaggacatg ggcagggaca 10200 aatacaggaa taaaagctgg ccaccccaac cagcagtggc aacccactca ggtcctcttc 10260 cctgctgtgg aagttttgtt cttttgatct tcacaataaa tcttgctgct gcccactctt 10320 tggatccctg ccgcctttaa gagctgtaac actcactgtg aaggtctgca ggaagtcagc 10380 gagaccacaa acccaccgga aggaacaaac tcaggacaca ccagaatgat ggtagaggtg 10440 ataaggcatg agacagaaat aataggaaag actttggatc caaatttctg atcaggcaat 10500 ttacaccaaa attcctcctc tccacttaga aaaggtgtgc tctgcgggac tattggctca 10560 ggggagactc aggaacttct ttttcttctt cctgcagtgc tctcatctga gcccttgaaa 10620 gaggggaaaa gaaactgtta gtagagccag gttgaaaaca acactctcct ctgtcttttg 10680 caggattcct gagctgaaat gcagatgacc acattcaagg aagaactttc tgccccggct 10740 ttgcaggatg aaaagctttc ctgcttggca gttattcttc cacaagagag ggctttctca 10800 ggacctggtt gctactggtt cggcaactgc agaaaatgtc ctcccttgtg gcttcctcag 10860 ctcctgccct tggcctgaag tcccagcatt gatggcag 10898 //