Dbfetch
ID LR813275; SV 1; linear; genomic DNA; STD; HUM; 13549 BP. XX AC LR813275; XX PR Project:PRJEB37962; XX DT 28-APR-2022 (Rel. 144, Created) DT 29-APR-2022 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens HLA-DPB1 gene for MHC class II antigen, allele DE HLA-DPB1*04:01:01:NEW XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Marsh GE S., Barker JOHN D.; RT ; RL Submitted (11-JUN-2020) to the INSDC. RL ANRI, HLA Informatics Group, Royal Free Hospital, London, NW3 2QG, NW3 2NU, RL United Kingdom XX DR MD5; a183ebb051b30385391d3d94f3f2661d. XX FH Key Location/Qualifiers FH FT source 1..13549 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /clone="AN300340" FT /db_xref="taxon:9606" FT CDS join(996..1095,5626..5889,9904..10185,10733..10843, FT 11173..11192) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAC9884362.1" FT /translation="MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECY FT AFNGTQRFLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDR FT MCRHNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQ FT EETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSA FT RSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA" FT exon 996..1095 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=1 FT intron 1096..5625 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=1 FT exon 5626..5889 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=2 FT intron 5890..9903 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=2 FT exon 9904..10185 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=3 FT intron 10186..10732 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=3 FT exon 10733..10843 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=4 FT intron 10844..11172 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=4 FT exon 11173..11192 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=5 XX SQ Sequence 13549 BP; 3710 A; 2979 C; 3413 G; 3447 T; 0 other; ctaaagtaag aagtaatgtt ctttgaaagt ttgtaaaaat attcactcta aacaaaatag 60 aatcagatgc tttgaaggag gtggggtctt tgatgatttt ttttcacttt cttccttatt 120 taccagtcaa tttatattct ctatggactt tatttttcca aagcaatttc agacctattg 180 atctcatttg atcttaagag ctttgctata aggcaggtta tatcatcccc atattgaaga 240 caaggaatcg aagtccaaga gaggcagtgt cgttaaagct gcatatttac atggtagggt 300 aggtggtgtg tccacgctcc cagtgtaagg tccctagact gagccctcct gaccctgatg 360 acagtcctgt ggaagaacct ggtaactcct gcacatcgca ggactcacag acctctggga 420 gaaagtaaat atgaatgggt gctaatctta aacacaccct tggacaaagg caagacagac 480 agactcagac ctcatttgag ttctgagatg ggtactctaa tccctctaag tcatgccact 540 gaatgacctt ttacacacta agatagcact ttttccacaa cagaccatgt cctgtgggtg 600 tgtgaggtgt ggcagaattg gggaaatgat aatccctgta gatgggccag cagaatattt 660 gagatcacct tcagagcaaa gaaaacgcat aatctcccca aacatcatga cttatctgac 720 tggttaaaat gagtatcact gtctttcctc cgtcatctta agtgcatcac aggctttata 780 ttttcagacc tttcatacta actttctgcc tagtgagcaa tgactcatac aaagctcagt 840 gtccattggt tcttttctca gactctgtcc aatcccaggg tcacagaaga ctacttgggt 900 tcatggtctc taatatttca aacaggagct ccctttagcg agtccttctt ttcctgactg 960 cagctctttt cattttgcca tccttttcca gctccatgat ggttctgcag gtttctgcgg 1020 ccccccggac agtggctctg acggcgttac tgatggtgct gctcacatct gtggtccagg 1080 gcagggccac tccaggtaag agccgaactg ccattcttgg agggtctggc tcagggaaca 1140 attcctaggg gacgttatct ttaagggatc aaattctgag acaggctgcg ggggctcctg 1200 ccctaaggca gtgtcctctc ttcccagcta gagaaagagg ttcatcccct ataggatagc 1260 ttgctaccct actggcctat tctctctcca aggacatggg tacagtaaac agagagaggt 1320 gcccagtggt cagtgtcttt ggggaaaatg ggaccaagag gtcctggata accttggaca 1380 gacaaggttt gcagagagag aagttggcaa gtgcaggctc ctgggcgtgt tcatgtctgc 1440 atccagcctg gaggggactc aggcagagag ccctaagctg gagtgtccag gctctgagga 1500 tcactgagga ttcagtgctc acgaagaatg cctcttattc cccagggtgg agcaggagcc 1560 cacatccctt ggacaattaa ggagagaagg gagggagggg gataggtttt agcccctgaa 1620 ggcattctca ttaaaggtac ttctcccagc ctccccagaa cttggttagg gtactagagt 1680 gggttgcgac ttgtaggaag aatgagatga ggttgtgtgg gtgcatgaca gggattgagt 1740 gtaggttatc agacagccaa ggaagcagta accaagtgaa aaatctcttc ttcctgctgc 1800 ctccctgtgg ctggtgtaat attatggcat ctatgatcca ttgtttttct ctcaggatac 1860 tctcaggata tttcttttta tatatatata tactttaagt tctagggtac atgtgcacaa 1920 cgtgcaggtt tgttacatat gtatacatgt gccatgttgg tgtgctgcac ccattaactc 1980 gtcatttaca ttaggtatat ttcctaatgc tatccctccc ccctcccccc accccacaac 2040 aggccccggt gtatgatgtt ccccttcctg tgtccatgtg ttctcattgt tcagttccca 2100 cctatgagtg agaacatgtg gtctttggtt ttttgtcctt gcaatagttt gctgtgaatg 2160 atgatttcca gcttcctcca tgtccctaca aaggacatga actcatcctt ttttatggct 2220 gcacagtatt ccatggtgta tatgtgtgca ttttcttaat ccagtctatc actgatggac 2280 agttgggttg gttccaagtc tttgctattg tgaatagtgc cgcaataaac atatgtgtgc 2340 atgtgtcttt atagcagcat gatttataat cctttgggta tatatccagt aatgggatgg 2400 ctgggtcaaa tggtatttct agttctagat ctttgaggaa ttgccacact gtcttgagat 2460 accatctcac accagttaaa atggcgatca ttaaaaagtc aggaaacaac aggtgctgga 2520 gaggatgtgg agaaatagga acacttttac tctgttggtg ggactgtaaa ctagttcaac 2580 cattgtactc tcaggacatt tctagtccaa atttacacca acactctgag aggaaggact 2640 gcaaagtagg taccttagtt ttccactgac ttccactttt cctgcttaca cccttcctcc 2700 tagacctctc cacacccctc ctaggacaca cctagaaggt actgacatca tgtcacctcc 2760 tcatctttca gggtagcaag gttggaatct cctgaataca gcccctcaag ccctaaaacc 2820 tcttatctat taccttgggt tcattgtcca ggaaggggag gagaacttga acttgtagtc 2880 acagaagggt gctgagaact aaccagcagg acggctcagc cctgggaact gcagaggggt 2940 gaggctgggg agagaggagg ctggagcagc actggtgaca ctgaacagtg tcaggaggaa 3000 gtgacggatg cagcgccccc atcccatagg cagagctgtc atgtgggatg agggacagtg 3060 ttgggagcca ccaaggaaac ccagaggtgg gggagcagag agcagaaggg ggcatgtgat 3120 gctgggcagt gaaagggagg acgggcaaag gctgggttga ggtttgtagg gggaatgaga 3180 tgaggcagtg gagccatgtg acagggactg agggtagatt actggagctc cctgcgtaga 3240 atgaatgttc aatcaaaacc tgctggaggg agagctggag ccatagggga gtgggtaaag 3300 tgggcagggc tgattccaca attccctgca tgctccccca actccacaca catccccaac 3360 ctcaaacagg gcacaagacc aaagggctga ggagccaggc tatagcttaa agaggctggg 3420 ggagaaaagc ttggctgaga caacccatag ggagctagag gtttttaata tatcctattc 3480 tgaataagag acgaattcat tcagatcagt ggtttcaaac cgtgctctgg gcaactcaat 3540 tgctaagggt tccacaaaca ggataaagtt tcttatatac aaaaaaaaat gaaggtttca 3600 aattacacca taaaacccct cattgcttat gtctacttgg caggtaaaat tccatttcaa 3660 aagttaaatg tacttaaaaa attacctaag actgggtaaa ttaaaaaaat taaatgttgc 3720 aaagaaaaaa ttcaaaattc ttattcttga atgaaaaacg ttctcttact ggtgattgag 3780 gaggagaaac aaagactaac aaatgaaaat gggagaatcc acactcagag tggggcaatt 3840 gaacaggcag gggcggatgg atggcagagg aggaggaatc tggactcaag gagctggggg 3900 gctctgggcc tggaatttta gggtctgggg cccaaggcac caggagaaga ggcaggtcag 3960 gatatctgag tcaagacctg ggatcttgcc ttagcaatga cactggagac taaaggtgga 4020 ctccatggtg cccttgagcc cagccctacc ccatctccac tatcctctgc caccagctgt 4080 gcaacttctg ctaggggtga ggttaataaa ctggagaagt taatttgtgg agcatgaaac 4140 agatgagcag aacaatcaca gcaccttaat ttccccagtg tgcccaagaa cagagcaggc 4200 ctgaagatac tcaaacagaa acaaacatgt gccgtgtcac tgataattct gtgtagacac 4260 acacctgcca gacactgctc atggcactcc ctaggaagaa cagcatgtgg gaaaggctgc 4320 caaaattgtt catgtaaaaa ttacatcaat gctgtcttcc tcggtgctgc ctatgcagct 4380 ggcagccatc tcttcctcca catcatggcc tccctcagac tcctcatgaa ggataagatc 4440 ctcaaaaaga ggaccaacaa gttcatgagg caccaatcag actgaaatgt caaaattaag 4500 cataactggc ggaaacccag aggtcttaac agtagggttc gtagaaggtc caagggccag 4560 atcttgatgc ccaacattgc ttatgggagc aacaacaaca acaaaaaaaa catgctgccc 4620 agtggcttcc agaagtttct ggtccacagc ctcaaggagc tgaaagtgct gctgatgtgc 4680 aacaaatctt actgtgctga gatcgctcac aaaatttcct ccagaactgc aaagtcatca 4740 tggaaagagt cacccagccg gccatcagag tcaccaaccc cagtaccagg gtgcacagct 4800 aagaaaatga gtagaaagtt catgtccacg ttttgtgtgt aaataaaacc ataaaaactg 4860 ccaaaaaaaa ttacatcaat gcctctaaac ccaaaggact ctacccccac aggtccctgg 4920 ttgttgtggt gattttcatt gtgtaaaata ctttccacat cttttgacac caagtctttc 4980 tgcagccatg tttgaaaatt aactttcagg ctacagagtc tttcttatac caaagttgaa 5040 gaaagtttta agaaatatat ttctacatct cctacatgca aaacaacagg agcaagttga 5100 ggaattctca agaaactggt cgagaagaga gagcgcttag ctatggaaaa gagaaagaag 5160 gaagggaggg cttcctggag gaggtggcat ttgaaccagg actgacatca ggatggaaat 5220 gtcagtcagg gagttaagta gggggagcag ctccgccctc cacgtcccca gctcctcccg 5280 cccctgtttt ttctcccagt gaccccacgt gaaacgtctc cgcctcctcc agccaccagc 5340 agaagggact gccttcccct cagtgctcgc ccctccctag tgatcactca gtgcccctga 5400 gctcattctt ttcagtaaat tctctctctg cgtggtgaga aaacaggcct ggagaggctc 5460 tgcgacccgc ttaggaccac agaactcggt actaggaaaa ctcctatttt aaaatccagc 5520 cctgggtggg aagatttggg aagaatcgtt aatattgaga gagagaggga gaaagaggat 5580 tagatgagag tggcgcctcc gctcatgtcc gccccctccc cgcagagaat taccttttcc 5640 agggacggca ggaatgctac gcgtttaatg ggacacagcg cttcctggag agatacatct 5700 acaaccggga ggagttcgcg cgcttcgaca gcgacgtggg ggagttccgg gcggtgacgg 5760 agctggggcg gcctgctgcg gagtactgga acagccagaa ggacatcctg gaggagaagc 5820 gggcagtgcc ggacaggatg tgcagacaca actacgagct gggcgggccc atgaccctgc 5880 agcgccgagg tgagtgaggg ctttgggccg gcggtcccag ggcagccccg cgggcccgtg 5940 cccagggcgc aggagcagcc gggttggcct aagggacctt agtgccgggc ggaaagggga 6000 ctttgggttg gggattcatg gggggagccc atctggagct tgtcagggga gcgagcgcgg 6060 ggacctggac tgggctgagc atggagtgag gaggacgaga gcagagagac ccccgggact 6120 tcatcaggcc tggcagctga ctgcatgtgg ggtgaaaaaa ggaagccaca ggacagcgca 6180 caagggtatg gtgtggagat ggaggtggag atggcacagc aggccacaca gagaagaaac 6240 ctacagggag gtagctgggt ttgaggtgct tgaggggcag atgggtggtc tgatgggcag 6300 gtagacagaa gggtctgcag ccggggagga gactgagata catgagacca tccagggaga 6360 ggggacccag ggggaagagc aaaggaccgg atcctgggaa ctggacagtt gtgatttggc 6420 caagacagaa aagcctgtga aagagaccaa aaaaacccaa gtgcagtgtg aggagaggcc 6480 cgcagagaag agtcttggaa gctgagggga ggtgacctca gcagcacagt ggacagcggt 6540 gccagtgact tgggaaggtc agaaaacaga agatggaaag tgggtttgga aaccagggag 6600 acctggggag agcaggttgg ccgcagcggc aggagctgga atgggagggg gtgcatgagg 6660 ctgagtgtgg cgcatcctcc tcggggctga gatggatttt acttgtcttg ggttccccac 6720 ggctgtcaca gggcagtgtc tcagttcatt cgtctttttc cttcaggaag tctgggtgta 6780 aagggatgga gagaggtgag gtgtgtgcag taagaggatt tctcaaggat gggacaggaa 6840 ggccttggag ctttggcttc ctcctgtgaa cttgtggggt ggggagcctg gtgcaccaac 6900 ctgagggact tgagggagta gtatcaggat gtgggattga gccctggacc ttttttctag 6960 aaagaggaaa aaaatgaagg gaggaggagg aggaagctgg ggagatcaca cctttgattt 7020 tcttgttcct ggaaagtgaa aggaagttca cctgctatga gtgagaaggt ggacacactg 7080 ggtggggatg aggtgagtga catgagctta ggaaagttgc tgaggtaatt ggttgagaga 7140 ggtgttcaaa taaaaataac gcaattggca aaaactgtta ctaagacttt gtagaggcac 7200 caatcagtga catggcagca ttttctttca cagtaatcaa ctgccagatt gcagacagcc 7260 ctgatgccag cctaaggagt gtgggtttct cctccaggcc cgcaggtccc caacctcact 7320 cctctgaaga ctcttctgga gatcctctgt gatgcacaga tctccagact cagtgccccc 7380 agactcagat tccctgggtg gggaggtctg gggatctctg cttgtaatca gctccctaga 7440 ggttcccatg tagccagata agtattgtca gaacactgaa gatttttgaa aaatgaaaaa 7500 gagaaggttg gagatgtgtc ttcagaagac tactaagggt gctggctaga ggagggacca 7560 gaggcaggga gatgaggtag gaaactgcta ttatttgtca gggaaattgc aatcaaggca 7620 tgagttagaa cagggaaaac acagaggcaa gggagaggtg gaagggggag gaaagaagta 7680 gtgacaattc cagggtggat gtccacccaa atctagaagt aattgagcaa atgttttctg 7740 ggcattagag aaggcaacta gaacaaacag gaatccttgc cttggtgaaa tgtatttgaa 7800 ctgggtcaga aatgaggcca ttgggtatca ggccttaact ccagcgcacc ctggaggtca 7860 ctgatgtggc tccaggctga cctgctcctg tcaaagaata ttgagcaaga tgcctctcgt 7920 ggaatgttct gggaccttaa aacagatacc caagtattcc ccctgatttc atggttccca 7980 gaagctctat ggggaagaaa ttgtaggtaa ttcacaactg agatttagac ataagttgaa 8040 tagtgtaatg gacattgagt taaccgaggt aatgaagtag tgagacacag gtgcccctga 8100 aataaactca cattgaggga agaggctgac aatgtggatc agtctgaaaa caaggcaaaa 8160 atacaatagg gagtaagggt tgtgtgtcag ttcaagactg tacttttacc tggcccagcg 8220 ccatgttagg gtatttgtgt tctccaggaa gtagaaagga aagaactgag tgattaggga 8280 cctagaagac taatttgaga cattcctctt gatgagctgt tctctagggt agtcctctga 8340 aagagctgtt ctctagtgga tctccctgaa tgaactgttc tctaggagca cttgaccctt 8400 ttctgtgttt gttttttgtt ttgtgtttgt gtttgttttt gagacaggtt ctcactttgt 8460 ctcccaggct ggagtgctgt ggcaccatca tggctcactg cagcctcaac ctcctgggct 8520 caagtgatcc tcctgcctca gcctcccatg tagctagaac tacagataca cgtaccacca 8580 tgtctggcta atttattttt ctttttagag atgggttctc actatgttgc ccaggccggt 8640 ctcaaaaccc tgggctcaag tgatcctcat gcctcaacct cccaaagtgc taagattata 8700 ggcatgacca ccatgcctgg ccttttctgc tttctgagga ggaaaaaggt actggtggca 8760 gagatccaaa agaaaagttg ccagtggcag tgtggaaatt cacctgagaa caacaggaca 8820 agctggggca caaatgcaaa gatgcagagg gaggcaacac ctggtcatct gtgagacctt 8880 catgggacct gaagacgcag cacagaggag gaacttgaaa aaggacggga tttctactac 8940 tcaagcatgt aggagctcag gatattctgt aaatatgaag attttgagtt tttgtaggtg 9000 aggtaaaaaa atacataggt tttttacaga ataagacatg taaagctctc ttcattttct 9060 ttgtattttc atgaagttat tagattcaca ggccaccata atgccattgt ctgtatatct 9120 taatttcaag atattatttg agtaaatttt gcttcctttg tatcaagata gaactttgaa 9180 aaggtaggta atttcacagt tgatcaaata ttctttgccc aaattacttt tggttaaaat 9240 ttctcctaaa tgtgctacag agtgcaaact ctgtctccct gccattccgc tatatactta 9300 ctaactatta ttttattcaa gatcatgcat gctctacttg aaggtctatt tctatctttt 9360 caatgctacc cttacccact agcctaatca cattattcct attttcaaca tctaggaatc 9420 aattacatag tgaacatgcc taagaaataa taatctgggc agatgcagtg gctcaggccc 9480 gtaatcccag ccctttgaga ggccgagcgg gtggatcact tgaggtcagg cgttggtcaa 9540 gtgctcctag agaaccaggc tgaccaacat ggagaaacct tgtctctact aataatacaa 9600 aaattagcca ggtgaagtgg caggcaccta taatcccagc tattcgggag gctgaggaag 9660 gagaattggt tgaagcccgg aggtggaggt tgcagtgagc caatattgcg ccactgcatt 9720 ccagacttgg caacagagtg acactccatc tcaacaaaaa gaaagaatga aagaaagaaa 9780 gagcgagatt atgtctcaaa aaaaaggaag gaaggaagga aggaaggaag gaaggaagga 9840 aggaaggaag gaaagaagga caatctcaaa ttctatttca ttatttttct tccacgctcc 9900 tagtccagcc tagggtgaat gtttccccct ccaagaaggg gcccttgcag caccacaacc 9960 tgcttgtctg ccacgtgacg gatttctacc caggcagcat tcaagtccga tggttcctga 10020 atggacagga ggaaacagct ggggtcgtgt ccaccaacct gatccgtaat ggagactgga 10080 ccttccagat cctggtgatg ctggaaatga ccccccagca gggagatgtc tacacctgcc 10140 aagtggagca caccagcctg gatagtcctg tcaccgtgga gtggagtgag tctctgatga 10200 ccctctagac cccacctctg aagagcaggg gactctctgg ctctggggtc cactcatctt 10260 atcttctgca tctataccct ggggccatgt ccaaacccca tctttcttct ataccagctc 10320 ctgagcatag tttgaagcca gggaaatgga gacttcctga ccttggctta ggggttcctg 10380 aagattcata gttctccccc ttgtcagaga atctagggac actgactggt ctcgaaaccc 10440 tcacacttag gaactgacct cacacatagt aacagttctc ttccttcagc attttagcct 10500 cttctcaggc attttgagag gcaacttcca gaatcagcat ttgccacctt gttgaggtca 10560 cacccctgtt ccagatatga gggtggctct ttctgaattt cctcttagca agctttttcc 10620 gctgcactgt cctcatcccg atatgctgca tcaggctcca gaatctcaga caggacatga 10680 gtagggatgc agctggtgga ggtgacacta aacctgggtc tgtccttccc agaggcacag 10740 tctgattctg cccggagtaa gacattgacg ggagctgggg gcttcgtgct ggggctcatc 10800 atctgtggag tgggcatctt catgcacagg aggagcaaga aaggtgagaa agcctgcagg 10860 gtgagcggga cttaccttcc cctggcatat tcacacttat tccacgatga ggggtttgac 10920 agaaaagaaa tgtcagaaag ctctagaggc cactgatatc agataatcgg ggaacaaaca 10980 tgacctatag cgagagaggg atcccaggct gggatcttaa tgcagccaga tgcatgaggt 11040 cccaagtact caggctcctg cggagcgtcc attgagtgat gggcaatgga atttggtggg 11100 atggaaatgt ttctctaatt atctgaggtg gtttcaatgg ctgattatat aacctttcgt 11160 ctttcatttc agttcaacga ggatctgcat aaacaggtaa tattcctgct ttgatttcct 11220 tgtggggtgg gttgcaggag gatatgagtc ctttctgtgc attgtaacac tgaggctcct 11280 ccaggaaggg aatctcaggc atgaacccct ctttcaatgt cagccttcag gcaagtgggg 11340 aaagagcatt gcttggctcc attgctgaag gaagcagaga tcaactctgt tatttatcag 11400 cctgagacgc atcctctcac cataattttt ctctcctgga cttacaggaa ggaggctggc 11460 aacctgggat aacttgtctt ttacccccac agggttcctg agctcactga aaagactatt 11520 gtgccttagg aaaagcattt gctgtgtttc gttagcatct ggctccagga cagaccttca 11580 acttccaaat tggatactgc tgccaagaag ttgctctgaa gtcagtttct atcattctgc 11640 tctttgattc aaagcactgt ttctctcact gggcctccaa ccatgttccc ttcttcttag 11700 caccacaaat aatcaaaacc caacatgact gtttgttttc ctttaaaaat atgcaccaaa 11760 tcatctctca tcacttttct ctgagggttt tagtagacag taggagttaa taaagaagtt 11820 cattttggtt taaacatagg aaagaagaga accatgaaaa tggggatatg ttaactattg 11880 tataatgggg cctgttacac atgacactct tctgaattga ctgtatttca gtgagctgcc 11940 cccaaatcaa gtttagtgcc ctcatccatt tatgtctcag accactattc ttaactattc 12000 aatggtgagc agactgcaaa tctgcctgat aggacccata ttcccacagc actaattcaa 12060 catatacctt actgagagca tgttttatca ttaccattaa gaagttaaat gaacatcaga 12120 atttaaaatc ataaatataa tctaatacac tttaaccatt ttctttgtgt gccatcacaa 12180 atactcctta accaaatacg gcttggactt ttgaatgcat ccaatagacg tcatttgtcg 12240 tctaagtctg cattcatcca ccagcctagg cctcctgtct taattttcat acagacagaa 12300 atgactcccc actggggaaa gagcaaagca atacatgtag cactcttttt caaacactgg 12360 tctttttttt tttcttaaca atccaacatt gttatgtgtt ttgcgtctca tattgacacc 12420 ttttggtcaa ggtagaggac atgtttgttg taagctttct ttttcgtgta gaggatggat 12480 tcttcactcc tgatacacac aatcagtgca cagcagctct cttatacatc cagttgatgc 12540 cttcagtctc cctggcttct tacaagcatc ttctgggcct tgtgtgtccc tgggcacctg 12600 tccctggtca attcccgaaa gctactgtgc tcctcttgcc catctcccct tgcaaataat 12660 atcttccatc gggggaccgg cttcctccaa tttcaggaga ggtggggctg aaggcacaga 12720 cttgggcgtc actggcacag atataagtaa atacagctgg agtctgcaga gaggctggac 12780 tgagtcaggg agtcaggaaa gagaagccac acacaaggac aaccaatcat gtttctcata 12840 atcttcttaa cctagggaat aggacacaat cattttttct ttttaaaaca tctttatccc 12900 tgatcagcct catttcctca aaaactataa aggaaaatgc tgctgacttg tttttgcgta 12960 gtaatttcag ctgtcacata ataagctaag gaagacagta tatagtaaat aaggaccctt 13020 tatctgtctt attttccctt ttggcttcac aggaaacttg tgagaaacct atgcagcata 13080 aaattaatat gatttcaatc cagggattca acgatggaag gaggtcatga gaatagcaga 13140 aagtcttcaa atcgagatca ttatgaaatc ctcagaccca gagcacataa atcctaccct 13200 cagagtcact gagcagttaa cattacaaat tacaaaccat atccagtcag agtcattctc 13260 tttcctgctt gtctcctgta ctcatgttac aggttagggc agtaccccga gtggagtgaa 13320 caatctctgg actaacactt gtcaggatca gaagctgagg tatctgcacc cacattacag 13380 gaacaggata tgtgctccta gggaactgag ggtgtcagga gatgaggaat gtccctggag 13440 tcacagaaag aaggtatcag atgtgtctca ctctgacata tgcaggtgtt tatgaaactc 13500 tgggatttct aaggaaggat gcagtgcaga gacaggtccc agaggagac 13549 // ID LR813287; SV 1; linear; genomic DNA; STD; HUM; 13545 BP. XX AC LR813287; XX PR Project:PRJEB37962; XX DT 28-APR-2022 (Rel. 144, Created) DT 29-APR-2022 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens HLA-DPB1 gene for MHC class II antigen, allele DE HLA-DPB1*04:01:01:NEW XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Marsh GE S., Barker JOHN D.; RT ; RL Submitted (11-JUN-2020) to the INSDC. RL ANRI, HLA Informatics Group, Royal Free Hospital, London, NW3 2QG, NW3 2NU, RL United Kingdom XX DR MD5; aa2baeec8f4c9ddc04b1625ac866999d. XX FH Key Location/Qualifiers FH FT source 1..13545 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /clone="AN300354" FT /db_xref="taxon:9606" FT CDS join(996..1095,5626..5889,9900..10181,10729..10839, FT 11169..11188) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAC9884374.1" FT /translation="MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECY FT AFNGTQRFLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDR FT MCRHNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQ FT EETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSA FT RSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA" FT exon 996..1095 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=1 FT intron 1096..5625 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=1 FT exon 5626..5889 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=2 FT intron 5890..9899 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=2 FT exon 9900..10181 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=3 FT intron 10182..10728 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=3 FT exon 10729..10839 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=4 FT intron 10840..11168 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=4 FT exon 11169..11188 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=5 XX SQ Sequence 13545 BP; 3709 A; 2979 C; 3411 G; 3446 T; 0 other; ctaaagtaag aagtaatgtt ctttgaaagt ttgtaaaaat attcactcta aacaaaatag 60 aatcagatgc tttgaaggag gtggggtctt tgatgatttt ttttcacttt cttccttatt 120 taccagtcaa tttatattct ctatggactt tatttttcca aagcaatttc agacctattg 180 atctcatttg atcttaagag ctttgctata aggcaggtta tatcatcccc atattgaaga 240 caaggaatcg aagtccaaga gaggcagtgt cgttaaagct gcatatttac atggtagggt 300 aggtggtgtg tccacgctcc cagtgtaagg tccctagact gagccctcct gaccctgatg 360 acagtcctgt ggaagaacct ggtaactcct gcacatcgca ggactcacag acctctggga 420 gaaagtaaat atgaatgggt gctaatctta aacacaccct tggacaaagg caagacagac 480 agactcagac ctcatttgag ttctgagatg ggtactctaa tccctctaag tcatgccact 540 gaatgacctt ttacacacta agatagcact ttttccacaa cagaccatgt cctgtgggtg 600 tgtgaggtgt ggcagaattg gggaaatgat aatccctgta gatgggccag cagaatattt 660 gagatcacct tcagagcaaa gaaaacgcat aatctcccca aacatcatga cttatctgac 720 tggttaaaat gagtatcact gtctttcctc cgtcatctta agtgcatcac aggctttata 780 ttttcagacc tttcatacta actttctgcc tagtgagcaa tgactcatac aaagctcagt 840 gtccattggt tcttttctca gactctgtcc aatcccaggg tcacagaaga ctacttgggt 900 tcatggtctc taatatttca aacaggagct ccctttagcg agtccttctt ttcctgactg 960 cagctctttt cattttgcca tccttttcca gctccatgat ggttctgcag gtttctgcgg 1020 ccccccggac agtggctctg acggcgttac tgatggtgct gctcacatct gtggtccagg 1080 gcagggccac tccaggtaag agccgaactg ccattcttgg agggtctggc tcagggaaca 1140 attcctaggg gacgttatct ttaagggatc aaattctgag acaggctgcg ggggctcctg 1200 ccctaaggca gtgtcctctc ttcccagcta gagaaagagg ttcatcccct ataggatagc 1260 ttgctaccct actggcctat tctctctcca aggacatggg tacagtaaac agagagaggt 1320 gcccagtggt cagtgtcttt ggggaaaatg ggaccaagag gtcctggata accttggaca 1380 gacaaggttt gcagagagag aagttggcaa gtgcaggctc ctgggcgtgt tcatgtctgc 1440 atccagcctg gaggggactc aggcagagag ccctaagctg gagtgtccag gctctgagga 1500 tcactgagga ttcagtgctc acgaagaatg cctcttattc cccagggtgg agcaggagcc 1560 cacatccctt ggacaattaa ggagagaagg gagggagggg gataggtttt agcccctgaa 1620 ggcattctca ttaaaggtac ttctcccagc ctccccagaa cttggttagg gtactagagt 1680 gggttgcgac ttgtaggaag aatgagatga ggttgtgtgg gtgcatgaca gggattgagt 1740 gtaggttatc agacagccaa ggaagcagta accaagtgaa aaatctcttc ttcctgctgc 1800 ctccctgtgg ctggtgtaat attatggcat ctatgatcca ttgtttttct ctcaggatac 1860 tctcaggata tttcttttta tatatatata tactttaagt tctagggtac atgtgcacaa 1920 cgtgcaggtt tgttacatat gtatacatgt gccatgttgg tgtgctgcac ccattaactc 1980 gtcatttaca ttaggtatat ttcctaatgc tatccctccc ccctcccccc accccacaac 2040 aggccccggt gtatgatgtt ccccttcctg tgtccatgtg ttctcattgt tcagttccca 2100 cctatgagtg agaacatgtg gtctttggtt ttttgtcctt gcaatagttt gctgtgaatg 2160 atgatttcca gcttcctcca tgtccctaca aaggacatga actcatcctt ttttatggct 2220 gcacagtatt ccatggtgta tatgtgtgca ttttcttaat ccagtctatc actgatggac 2280 agttgggttg gttccaagtc tttgctattg tgaatagtgc cgcaataaac atatgtgtgc 2340 atgtgtcttt atagcagcat gatttataat cctttgggta tatatccagt aatgggatgg 2400 ctgggtcaaa tggtatttct agttctagat ctttgaggaa ttgccacact gtcttgagat 2460 accatctcac accagttaaa atggcgatca ttaaaaagtc aggaaacaac aggtgctgga 2520 gaggatgtgg agaaatagga acacttttac tctgttggtg ggactgtaaa ctagttcaac 2580 cattgtactc tcaggacatt tctagtccaa atttacacca acactctgag aggaaggact 2640 gcaaagtagg taccttagtt ttccactgac ttccactttt cctgcttaca cccttcctcc 2700 tagacctctc cacacccctc ctaggacaca cctagaaggt actgacatca tgtcacctcc 2760 tcatctttca gggtagcaag gttggaatct cctgaataca gcccctcaag ccctaaaacc 2820 tcttatctat taccttgggt tcattgtcca ggaaggggag gagaacttga acttgtagtc 2880 acagaagggt gctgagaact aaccagcagg acggctcagc cctgggaact gcagaggggt 2940 gaggctgggg agagaggagg ctggagcagc actggtgaca ctgaacagtg tcaggaggaa 3000 gtgacggatg cagcgccccc atcccatagg cagagctgtc atgtgggatg agggacagtg 3060 ttgggagcca ccaaggaaac ccagaggtgg gggagcagag agcagaaggg ggcatgtgat 3120 gctgggcagt gaaagggagg acgggcaaag gctgggttga ggtttgtagg gggaatgaga 3180 tgaggcagtg gagccatgtg acagggactg agggtagatt actggagctc cctgcgtaga 3240 atgaatgttc aatcaaaacc tgctggaggg agagctggag ccatagggga gtgggtaaag 3300 tgggcagggc tgattccaca attccctgca tgctccccca actccacaca catccccaac 3360 ctcaaacagg gcacaagacc aaagggctga ggagccaggc tatagcttaa agaggctggg 3420 ggagaaaagc ttggctgaga caacccatag ggagctagag gtttttaata tatcctattc 3480 tgaataagag acgaattcat tcagatcagt ggtttcaaac cgtgctctgg gcaactcaat 3540 tgctaagggt tccacaaaca ggataaagtt tcttatatac aaaaaaaaat gaaggtttca 3600 aattacacca taaaacccct cattgcttat gtctacttgg caggtaaaat tccatttcaa 3660 aagttaaatg tacttaaaaa attacctaag actgggtaaa ttaaaaaaat taaatgttgc 3720 aaagaaaaaa ttcaaaattc ttattcttga atgaaaaacg ttctcttact ggtgattgag 3780 gaggagaaac aaagactaac aaatgaaaat gggagaatcc acactcagag tggggcaatt 3840 gaacaggcag gggcggatgg atggcagagg aggaggaatc tggactcaag gagctggggg 3900 gctctgggcc tggaatttta gggtctgggg cccaaggcac caggagaaga ggcaggtcag 3960 gatatctgag tcaagacctg ggatcttgcc ttagcaatga cactggagac taaaggtgga 4020 ctccatggtg cccttgagcc cagccctacc ccatctccac tatcctctgc caccagctgt 4080 gcaacttctg ctaggggtga ggttaataaa ctggagaagt taatttgtgg agcatgaaac 4140 agatgagcag aacaatcaca gcaccttaat ttccccagtg tgcccaagaa cagagcaggc 4200 ctgaagatac tcaaacagaa acaaacatgt gccgtgtcac tgataattct gtgtagacac 4260 acacctgcca gacactgctc atggcactcc ctaggaagaa cagcatgtgg gaaaggctgc 4320 caaaattgtt catgtaaaaa ttacatcaat gctgtcttcc tcggtgctgc ctatgcagct 4380 ggcagccatc tcttcctcca catcatggcc tccctcagac tcctcatgaa ggataagatc 4440 ctcaaaaaga ggaccaacaa gttcatgagg caccaatcag actgaaatgt caaaattaag 4500 cataactggc ggaaacccag aggtcttaac agtagggttc gtagaaggtc caagggccag 4560 atcttgatgc ccaacattgc ttatgggagc aacaacaaca acaaaaaaaa catgctgccc 4620 agtggcttcc agaagtttct ggtccacagc ctcaaggagc tgaaagtgct gctgatgtgc 4680 aacaaatctt actgtgctga gatcgctcac aaaatttcct ccagaactgc aaagtcatca 4740 tggaaagagt cacccagccg gccatcagag tcaccaaccc cagtaccagg gtgcacagct 4800 aagaaaatga gtagaaagtt catgtccacg ttttgtgtgt aaataaaacc ataaaaactg 4860 ccaaaaaaaa ttacatcaat gcctctaaac ccaaaggact ctacccccac aggtccctgg 4920 ttgttgtggt gattttcatt gtgtaaaata ctttccacat cttttgacac caagtctttc 4980 tgcagccatg tttgaaaatt aactttcagg ctacagagtc tttcttatac caaagttgaa 5040 gaaagtttta agaaatatat ttctacatct cctacatgca aaacaacagg agcaagttga 5100 ggaattctca agaaactggt cgagaagaga gagcgcttag ctatggaaaa gagaaagaag 5160 gaagggaggg cttcctggag gaggtggcat ttgaaccagg actgacatca ggatggaaat 5220 gtcagtcagg gagttaagta gggggagcag ctccgccctc cacgtcccca gctcctcccg 5280 cccctgtttt ttctcccagt gaccccacgt gaaacgtctc cgcctcctcc agccaccagc 5340 agaagggact gccttcccct cagtgctcgc ccctccctag tgatcactca gtgcccctga 5400 gctcattctt ttcagtaaat tctctctctg cgtggtgaga aaacaggcct ggagaggctc 5460 tgcgacccgc ttaggaccac agaactcggt actaggaaaa ctcctatttt aaaatccagc 5520 cctgggtggg aagatttggg aagaatcgtt aatattgaga gagagaggga gaaagaggat 5580 tagatgagag tggcgcctcc gctcatgtcc gccccctccc cgcagagaat taccttttcc 5640 agggacggca ggaatgctac gcgtttaatg ggacacagcg cttcctggag agatacatct 5700 acaaccggga ggagttcgcg cgcttcgaca gcgacgtggg ggagttccgg gcggtgacgg 5760 agctggggcg gcctgctgcg gagtactgga acagccagaa ggacatcctg gaggagaagc 5820 gggcagtgcc ggacaggatg tgcagacaca actacgagct gggcgggccc atgaccctgc 5880 agcgccgagg tgagtgaggg ctttgggccg gcggtcccag ggcagccccg cgggcccgtg 5940 cccagggcgc aggagcagcc gggttggcct aagggacctt agtgccgggc ggaaagggga 6000 ctttgggttg gggattcatg gggggagccc atctggagct tgtcagggga gcgagcgcgg 6060 ggacctggac tgggctgagc atggagtgag gaggacgaga gcagagagac ccccgggact 6120 tcatcaggcc tggcagctga ctgcatgtgg ggtgaaaaaa ggaagccaca ggacagcgca 6180 caagggtatg gtgtggagat ggaggtggag atggcacagc aggccacaca gagaagaaac 6240 ctacagggag gtagctgggt ttgaggtgct tgaggggcag atgggtggtc tgatgggcag 6300 gtagacagaa gggtctgcag ccggggagga gactgagata catgagacca tccagggaga 6360 ggggacccag ggggaagagc aaaggaccgg atcctgggaa ctggacagtt gtgatttggc 6420 caagacagaa aagcctgtga aagagaccaa aaaaacccaa gtgcagtgtg aggagaggcc 6480 cgcagagaag agtcttggaa gctgagggga ggtgacctca gcagcacagt ggacagcggt 6540 gccagtgact tgggaaggtc agaaaacaga agatggaaag tgggtttgga aaccagggag 6600 acctggggag agcaggttgg ccgcagcggc aggagctgga atgggagggg gtgcatgagg 6660 ctgagtgtgg cgcatcctcc tcggggctga gatggatttt acttgtcttg ggttccccac 6720 ggctgtcaca gggcagtgtc tcagttcatt cgtctttttc cttcaggaag tctgggtgta 6780 aagggatgga gagaggtgag gtgtgtgcag taagaggatt tctcaaggat gggacaggaa 6840 ggccttggag ctttggcttc ctcctgtgaa cttgtggggt ggggagcctg gtgcaccaac 6900 ctgagggact tgagggagta gtatcaggat gtgggattga gccctggacc ttttttctag 6960 aaagaggaaa aaaatgaagg gaggaggagg aggaagctgg ggagatcaca cctttgattt 7020 tcttgttcct ggaaagtgaa aggaagttca cctgctatga gtgagaaggt ggacacactg 7080 ggtggggatg aggtgagtga catgagctta ggaaagttgc tgaggtaatt ggttgagaga 7140 ggtgttcaaa taaaaataac gcaattggca aaaactgtta ctaagacttt gtagaggcac 7200 caatcagtga catggcagca ttttctttca cagtaatcaa ctgccagatt gcagacagcc 7260 ctgatgccag cctaaggagt gtgggtttct cctccaggcc cgcaggtccc caacctcact 7320 cctctgaaga ctcttctgga gatcctctgt gatgcacaga tctccagact cactgccccg 7380 agactcagat tccctgggta gggaggtctg gggatctctg cttgtaatca gctccctaga 7440 ggttcccatg tagccagata agtattgtca gaacactgaa gatttttgaa aaatgaaaaa 7500 gagaaggttg gagatgtgtc ttcagaagac tactaagggt gctggctaga ggagggacca 7560 gaggcaggga gatgaggtag gaaactgcta ttatttgtca gggaaattgc aatcaaggca 7620 tgagttagaa cagggaaaac acagaggcaa gggagaggtg gaagggggag gaaagaagta 7680 gtgacaattc cagggtggat gtccacccaa atctagaagt aattgagcaa atgttttctg 7740 ggcattagag aaggcaacta gaacaaacag gaatccttgc cttggtgaaa tgtatttgaa 7800 ctgggtcaga aatgaggcca ttgggtatca ggccttaact ccagcgcacc ctggaggtca 7860 ctgatgtggc tccaggctga cctgctcctg tcaaagaata ttgagcaaga tgcctctcgt 7920 ggaatgttct gggaccttaa aacagatacc caagtattcc ccctgatttc atggttccca 7980 gaagctctat ggggaagaaa ttgtaggtaa ttcacaactg agatttagac ataagttgaa 8040 tagtgtaatg gacattgagt taaccgaggt aatgaagtag tgagacacag gtgcccctga 8100 aataaactca cattgaggga agaggctgac aatgtggatc agtctgaaaa caaggcaaaa 8160 atacaatagg gagtaagggt tgtgtgtcag ttcaagactg tacttttacc tggcccagcg 8220 ccatgttagg gtatttgtgt tctccaggaa gtagaaagga aagaactgag tgattaggga 8280 cctagaagac taatttgaga cattcctctt gatgagctgt tctctagggt agtcctctga 8340 aagagctgtt ctctagtgga tctccctgaa tgaactgttc tctaggagca cttgaccctt 8400 ttctgtgttt gttttttgtt ttgtgtttgt gtttgttttt gagacaggtt ctcactttgt 8460 ctcccaggct ggagtgctgt ggcaccatca tggctcactg cagcctcaac ctcctgggct 8520 caagtgatcc tcctgcctca gcctcccatg tagctagaac tacagataca cgtaccacca 8580 tgtctggcta atttattttt ctttttagag atgggttctc actatgttgc ccaggccggt 8640 ctcaaaaccc tgggctcaag tgatcctcat gcctcaacct cccaaagtgc taagattata 8700 ggcatgacca ccatgcctgg ccttttctgc tttctgagga ggaaaaaggt actggtggca 8760 gagatccaaa agaaaagttg ccagtggcag tgtggaaatt cacctgagaa caacaggaca 8820 agctggggca caaatgcaaa gatgcagagg gaggcaacac ctggtcatct gtgagacctt 8880 catgggacct gaagacgcag cacagaggag gaacttgaaa aaggacggga tttctactac 8940 tcaagcatgt aggagctcag gatattctgt aaatatgaag attttgagtt tttgtaggtg 9000 aggtaaaaaa atacataggt tttttacaga ataagacatg taaagctctc ttcattttct 9060 ttgtattttc atgaagttat tagattcaca ggccaccata atgccattgt ctgtatatct 9120 taatttcaag atattatttg agtaaatttt gcttcctttg tatcaagata gaactttgaa 9180 aaggtaggta atttcacagt tgatcaaata ttctttgccc aaattacttt tggttaaaat 9240 ttctcctaaa tgtgctacag agtgcaaact ctgtctccct gccattccgc tatatactta 9300 ctaactatta ttttattcaa gatcatgcat gctctacttg aaggtctatt tctatctttt 9360 caatgctacc cttacccact agcctaatca cattattcct attttcaaca tctaggaatc 9420 aattacatag tgaacatgcc taagaaataa taatctgggc agatgcagtg gctcaggccc 9480 gtaatcccag ccctttgaga ggccgagcgg gtggatcact tgaggtcagg cgttggtcaa 9540 gtgctcctag agaaccaggc tgaccaacat ggagaaacct tgtctctact aataatacaa 9600 aaattagcca ggtgaagtgg caggcaccta taatcccagc tattcgggag gctgaggaag 9660 gagaattggt tgaagcccgg aggtggaggt tgcagtgagc caatattgcg ccactgcatt 9720 ccagacttgg caacagagtg acactccatc tcaacaaaaa gaaagaatga aagaaagaaa 9780 gagcgagatt atgtctcaaa aaaaaggaag gaaggaagga aggaaggaag gaaggaagga 9840 aggaaggaaa gaaggacaat ctcaaattct atttcattat ttttcttcca cgctcctagt 9900 ccagcctagg gtgaatgttt ccccctccaa gaaggggccc ttgcagcacc acaacctgct 9960 tgtctgccac gtgacggatt tctacccagg cagcattcaa gtccgatggt tcctgaatgg 10020 acaggaggaa acagctgggg tcgtgtccac caacctgatc cgtaatggag actggacctt 10080 ccagatcctg gtgatgctgg aaatgacccc ccagcaggga gatgtctaca cctgccaagt 10140 ggagcacacc agcctggata gtcctgtcac cgtggagtgg agtgagtctc tgatgaccct 10200 ctagacccca cctctgaaga gcaggggact ctctggctct ggggtccact catcttatct 10260 tctgcatcta taccctgggg ccatgtccaa accccatctt tcttctatac cagctcctga 10320 gcatagtttg aagccaggga aatggagact tcctgacctt ggcttagggg ttcctgaaga 10380 ttcatagttc tcccccttgt cagagaatct agggacactg actggtctcg aaaccctcac 10440 acttaggaac tgacctcaca cataggaaca gttctcttcc ttcagcattt tagcctcttc 10500 tcaggcattt tgagaggcaa cttccagaat cagcatttgc caccttgttg aggtcacacc 10560 cctgttccag atatgagggt ggctctttct gaatttcctc ttagcaagct ttttccgctg 10620 cactgtcctc atcccgatat gctgcatcag gctccagaat ctcagacagg acatgagtag 10680 ggatgcagct ggtggaggtg acactaaacc tgggtctgtc cttcccagag gcacagtctg 10740 attctgcccg gagtaagaca ttgacgggag ctgggggctt cgtgctgggg ctcatcatct 10800 gtggagtggg catcttcatg cacaggagga gcaagaaagg tgagaaagcc tgcagggtga 10860 gcgggactta ccttcccctg gcatattcac acttattcca cgatgagggg tttgacagaa 10920 aagaaatgtc agaaagctct agaggccact gatatcagat aatcggggaa caaacatgac 10980 ctatagcgag agagggatcc caggctggga tcttaatgca gccagatgca tgaggtccca 11040 agtactcagg ctcctgcgga gcgtccattg agtgatgggc aatggaattt ggtgggatgg 11100 aaatgtttct ctaattatct gaggtggttt caatggctga ttatataacc tttcgtcttt 11160 catttcagtt caacgaggat ctgcataaac aggtaatatt cctgctttga tttccttgtg 11220 gggtgggttg caggaggata tgagtccttt ctgtgcattg taacactgag gctcctccag 11280 gaagggaatc tcaggcatga acccctcttt caatgtcagc cttcaggcaa gtggggaaag 11340 agcattgctt ggctccattg ctgaaggaag cagagatcaa ctctgttatt tatcagcctg 11400 agacgcatcc tctcaccata atttttctct cctggactta caggaaggag gctggcaacc 11460 tgggataact tgtcttttac ccccacaggg ttcctgagct cactgaaaag actattgtgc 11520 cttaggaaaa gcatttgctg tgtttcgtta gcatctggct ccaggacaga ccttcaactt 11580 ccaaattgga tactgctgcc aagaagttgc tctgaagtca gtttctatca ttctgctctt 11640 tgattcaaag cactgtttct ctcactgggc ctccaaccat gttcccttct tcttagcacc 11700 acaaataatc aaaacccaac atgactgttt gttttccttt aaaaatatgc accaaatcat 11760 ctctcatcac ttttctctga gggttttagt agacagtagg agttaataaa gaagttcatt 11820 ttggtttaaa cataggaaag aagagaacca tgaaaatggg gatatgttaa ctattgtata 11880 atggggcctg ttacacatga cactcttctg aattgactgt atttcagtga gctgccccca 11940 aatcaagttt agtgccctca tccatttatg tctcagacca ctattcttaa ctattcaatg 12000 gtgagcagac tgcaaatctg cctgatagga cccatattcc cacagcacta attcaacata 12060 taccttactg agagcatgtt ttatcattac cattaagaag ttaaatgaac atcagaattt 12120 aaaatcataa atataatcta atacacttta accattttct ttgtgtgcca tcacaaatac 12180 tccttaacca aatacggctt ggacttttga atgcatccaa tagacgtcat ttgtcgtcta 12240 agtctgcatt catccaccag cctaggcctc ctgtcttaat tttcatacag acagaaatga 12300 ctccccactg gggaaagagc aaagcaatac atgtagcact ctttttcaaa cactggtctt 12360 tttttttttc ttaacaatcc aacattgtta tgtgttttgc gtctcatatt gacacctttt 12420 ggtcaaggta gaggacatgt ttgttgtaag ctttcttttt cgtgtagagg atggattctt 12480 cactcctgat acacacaatc agtgcacagc agctctctta tacatccagt tgatgccttc 12540 agtctccctg gcttcttaca agcatcttct gggccttgtg tgtccctggg cacctgtccc 12600 tggtcaattc ccgaaagcta ctgtgctcct cttgcccatc tccccttgca aataatatct 12660 tccatcgggg gaccggcttc ctccaatttc aggagaggtg gggctgaagg cacagacttg 12720 ggcgtcactg gcacagatat aagtaaatac agctggagtc tgcagagagg ctggactgag 12780 tcagggagtc aggaaagaga agccacacac aaggacaacc aatcatgttt ctcataatct 12840 tcttaaccta gggaatagga cacaatcatt ttttcttttt aaaacatctt tatccctgat 12900 cagcctcatt tcctcaaaaa ctataaagga aaatgctgct gacttgtttt tgcgtagtaa 12960 tttcagctgt cacataataa gctaaggaag acagtatata gtaaataagg accctttatc 13020 tgtcttattt tcccttttgg cttcacagga aacttgtgag aaacctatgc agcataaaat 13080 taatatgatt tcaatccagg gattcaacga tggaaggagg tcatgagaat agcagaaagt 13140 cttcaaatcg agatcattat gaaatcctca gacccagagc acataaatcc taccctcaga 13200 gtcactgagc agttaacatt acaaattaca aaccatatcc agtcagagtc attctctttc 13260 ctgcttgtct cctgtactca tgttacaggt tagggcagta ccccgagtgg agtgaacaat 13320 ctctggacta acacttgtca ggatcagaag ctgaggtatc tgcacccaca ttacaggaac 13380 aggatatgtg ctcctaggga actgagggtg tcaggagatg aggaatgtcc ctggagtcac 13440 agaaagaagg tatcagatgt gtctcactct gacatatgca ggtgtttatg aaactctggg 13500 atttctaagg aaggatgcag tgcagagaca ggtcccagag gagac 13545 // ID LR813369; SV 1; linear; genomic DNA; STD; HUM; 13549 BP. XX AC LR813369; XX PR Project:PRJEB37962; XX DT 28-APR-2022 (Rel. 144, Created) DT 29-APR-2022 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens HLA-DPB1 gene for MHC class II antigen, allele DE HLA-DPB1*04:01:01:NEW XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Marsh GE S., Barker JOHN D.; RT ; RL Submitted (11-JUN-2020) to the INSDC. RL ANRI, HLA Informatics Group, Royal Free Hospital, London, NW3 2QG, NW3 2NU, RL United Kingdom XX DR MD5; a183ebb051b30385391d3d94f3f2661d. XX FH Key Location/Qualifiers FH FT source 1..13549 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /clone="AN300438" FT /db_xref="taxon:9606" FT CDS join(996..1095,5626..5889,9904..10185,10733..10843, FT 11173..11192) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAC9884456.1" FT /translation="MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECY FT AFNGTQRFLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDR FT MCRHNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQ FT EETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSA FT RSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA" FT exon 996..1095 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=1 FT intron 1096..5625 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=1 FT exon 5626..5889 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=2 FT intron 5890..9903 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=2 FT exon 9904..10185 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=3 FT intron 10186..10732 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=3 FT exon 10733..10843 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=4 FT intron 10844..11172 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=4 FT exon 11173..11192 FT /gene="HLA-DPB1" FT /allele="HLA-DPB1*04:01:01:NEW" FT /number=5 XX SQ Sequence 13549 BP; 3710 A; 2979 C; 3413 G; 3447 T; 0 other; ctaaagtaag aagtaatgtt ctttgaaagt ttgtaaaaat attcactcta aacaaaatag 60 aatcagatgc tttgaaggag gtggggtctt tgatgatttt ttttcacttt cttccttatt 120 taccagtcaa tttatattct ctatggactt tatttttcca aagcaatttc agacctattg 180 atctcatttg atcttaagag ctttgctata aggcaggtta tatcatcccc atattgaaga 240 caaggaatcg aagtccaaga gaggcagtgt cgttaaagct gcatatttac atggtagggt 300 aggtggtgtg tccacgctcc cagtgtaagg tccctagact gagccctcct gaccctgatg 360 acagtcctgt ggaagaacct ggtaactcct gcacatcgca ggactcacag acctctggga 420 gaaagtaaat atgaatgggt gctaatctta aacacaccct tggacaaagg caagacagac 480 agactcagac ctcatttgag ttctgagatg ggtactctaa tccctctaag tcatgccact 540 gaatgacctt ttacacacta agatagcact ttttccacaa cagaccatgt cctgtgggtg 600 tgtgaggtgt ggcagaattg gggaaatgat aatccctgta gatgggccag cagaatattt 660 gagatcacct tcagagcaaa gaaaacgcat aatctcccca aacatcatga cttatctgac 720 tggttaaaat gagtatcact gtctttcctc cgtcatctta agtgcatcac aggctttata 780 ttttcagacc tttcatacta actttctgcc tagtgagcaa tgactcatac aaagctcagt 840 gtccattggt tcttttctca gactctgtcc aatcccaggg tcacagaaga ctacttgggt 900 tcatggtctc taatatttca aacaggagct ccctttagcg agtccttctt ttcctgactg 960 cagctctttt cattttgcca tccttttcca gctccatgat ggttctgcag gtttctgcgg 1020 ccccccggac agtggctctg acggcgttac tgatggtgct gctcacatct gtggtccagg 1080 gcagggccac tccaggtaag agccgaactg ccattcttgg agggtctggc tcagggaaca 1140 attcctaggg gacgttatct ttaagggatc aaattctgag acaggctgcg ggggctcctg 1200 ccctaaggca gtgtcctctc ttcccagcta gagaaagagg ttcatcccct ataggatagc 1260 ttgctaccct actggcctat tctctctcca aggacatggg tacagtaaac agagagaggt 1320 gcccagtggt cagtgtcttt ggggaaaatg ggaccaagag gtcctggata accttggaca 1380 gacaaggttt gcagagagag aagttggcaa gtgcaggctc ctgggcgtgt tcatgtctgc 1440 atccagcctg gaggggactc aggcagagag ccctaagctg gagtgtccag gctctgagga 1500 tcactgagga ttcagtgctc acgaagaatg cctcttattc cccagggtgg agcaggagcc 1560 cacatccctt ggacaattaa ggagagaagg gagggagggg gataggtttt agcccctgaa 1620 ggcattctca ttaaaggtac ttctcccagc ctccccagaa cttggttagg gtactagagt 1680 gggttgcgac ttgtaggaag aatgagatga ggttgtgtgg gtgcatgaca gggattgagt 1740 gtaggttatc agacagccaa ggaagcagta accaagtgaa aaatctcttc ttcctgctgc 1800 ctccctgtgg ctggtgtaat attatggcat ctatgatcca ttgtttttct ctcaggatac 1860 tctcaggata tttcttttta tatatatata tactttaagt tctagggtac atgtgcacaa 1920 cgtgcaggtt tgttacatat gtatacatgt gccatgttgg tgtgctgcac ccattaactc 1980 gtcatttaca ttaggtatat ttcctaatgc tatccctccc ccctcccccc accccacaac 2040 aggccccggt gtatgatgtt ccccttcctg tgtccatgtg ttctcattgt tcagttccca 2100 cctatgagtg agaacatgtg gtctttggtt ttttgtcctt gcaatagttt gctgtgaatg 2160 atgatttcca gcttcctcca tgtccctaca aaggacatga actcatcctt ttttatggct 2220 gcacagtatt ccatggtgta tatgtgtgca ttttcttaat ccagtctatc actgatggac 2280 agttgggttg gttccaagtc tttgctattg tgaatagtgc cgcaataaac atatgtgtgc 2340 atgtgtcttt atagcagcat gatttataat cctttgggta tatatccagt aatgggatgg 2400 ctgggtcaaa tggtatttct agttctagat ctttgaggaa ttgccacact gtcttgagat 2460 accatctcac accagttaaa atggcgatca ttaaaaagtc aggaaacaac aggtgctgga 2520 gaggatgtgg agaaatagga acacttttac tctgttggtg ggactgtaaa ctagttcaac 2580 cattgtactc tcaggacatt tctagtccaa atttacacca acactctgag aggaaggact 2640 gcaaagtagg taccttagtt ttccactgac ttccactttt cctgcttaca cccttcctcc 2700 tagacctctc cacacccctc ctaggacaca cctagaaggt actgacatca tgtcacctcc 2760 tcatctttca gggtagcaag gttggaatct cctgaataca gcccctcaag ccctaaaacc 2820 tcttatctat taccttgggt tcattgtcca ggaaggggag gagaacttga acttgtagtc 2880 acagaagggt gctgagaact aaccagcagg acggctcagc cctgggaact gcagaggggt 2940 gaggctgggg agagaggagg ctggagcagc actggtgaca ctgaacagtg tcaggaggaa 3000 gtgacggatg cagcgccccc atcccatagg cagagctgtc atgtgggatg agggacagtg 3060 ttgggagcca ccaaggaaac ccagaggtgg gggagcagag agcagaaggg ggcatgtgat 3120 gctgggcagt gaaagggagg acgggcaaag gctgggttga ggtttgtagg gggaatgaga 3180 tgaggcagtg gagccatgtg acagggactg agggtagatt actggagctc cctgcgtaga 3240 atgaatgttc aatcaaaacc tgctggaggg agagctggag ccatagggga gtgggtaaag 3300 tgggcagggc tgattccaca attccctgca tgctccccca actccacaca catccccaac 3360 ctcaaacagg gcacaagacc aaagggctga ggagccaggc tatagcttaa agaggctggg 3420 ggagaaaagc ttggctgaga caacccatag ggagctagag gtttttaata tatcctattc 3480 tgaataagag acgaattcat tcagatcagt ggtttcaaac cgtgctctgg gcaactcaat 3540 tgctaagggt tccacaaaca ggataaagtt tcttatatac aaaaaaaaat gaaggtttca 3600 aattacacca taaaacccct cattgcttat gtctacttgg caggtaaaat tccatttcaa 3660 aagttaaatg tacttaaaaa attacctaag actgggtaaa ttaaaaaaat taaatgttgc 3720 aaagaaaaaa ttcaaaattc ttattcttga atgaaaaacg ttctcttact ggtgattgag 3780 gaggagaaac aaagactaac aaatgaaaat gggagaatcc acactcagag tggggcaatt 3840 gaacaggcag gggcggatgg atggcagagg aggaggaatc tggactcaag gagctggggg 3900 gctctgggcc tggaatttta gggtctgggg cccaaggcac caggagaaga ggcaggtcag 3960 gatatctgag tcaagacctg ggatcttgcc ttagcaatga cactggagac taaaggtgga 4020 ctccatggtg cccttgagcc cagccctacc ccatctccac tatcctctgc caccagctgt 4080 gcaacttctg ctaggggtga ggttaataaa ctggagaagt taatttgtgg agcatgaaac 4140 agatgagcag aacaatcaca gcaccttaat ttccccagtg tgcccaagaa cagagcaggc 4200 ctgaagatac tcaaacagaa acaaacatgt gccgtgtcac tgataattct gtgtagacac 4260 acacctgcca gacactgctc atggcactcc ctaggaagaa cagcatgtgg gaaaggctgc 4320 caaaattgtt catgtaaaaa ttacatcaat gctgtcttcc tcggtgctgc ctatgcagct 4380 ggcagccatc tcttcctcca catcatggcc tccctcagac tcctcatgaa ggataagatc 4440 ctcaaaaaga ggaccaacaa gttcatgagg caccaatcag actgaaatgt caaaattaag 4500 cataactggc ggaaacccag aggtcttaac agtagggttc gtagaaggtc caagggccag 4560 atcttgatgc ccaacattgc ttatgggagc aacaacaaca acaaaaaaaa catgctgccc 4620 agtggcttcc agaagtttct ggtccacagc ctcaaggagc tgaaagtgct gctgatgtgc 4680 aacaaatctt actgtgctga gatcgctcac aaaatttcct ccagaactgc aaagtcatca 4740 tggaaagagt cacccagccg gccatcagag tcaccaaccc cagtaccagg gtgcacagct 4800 aagaaaatga gtagaaagtt catgtccacg ttttgtgtgt aaataaaacc ataaaaactg 4860 ccaaaaaaaa ttacatcaat gcctctaaac ccaaaggact ctacccccac aggtccctgg 4920 ttgttgtggt gattttcatt gtgtaaaata ctttccacat cttttgacac caagtctttc 4980 tgcagccatg tttgaaaatt aactttcagg ctacagagtc tttcttatac caaagttgaa 5040 gaaagtttta agaaatatat ttctacatct cctacatgca aaacaacagg agcaagttga 5100 ggaattctca agaaactggt cgagaagaga gagcgcttag ctatggaaaa gagaaagaag 5160 gaagggaggg cttcctggag gaggtggcat ttgaaccagg actgacatca ggatggaaat 5220 gtcagtcagg gagttaagta gggggagcag ctccgccctc cacgtcccca gctcctcccg 5280 cccctgtttt ttctcccagt gaccccacgt gaaacgtctc cgcctcctcc agccaccagc 5340 agaagggact gccttcccct cagtgctcgc ccctccctag tgatcactca gtgcccctga 5400 gctcattctt ttcagtaaat tctctctctg cgtggtgaga aaacaggcct ggagaggctc 5460 tgcgacccgc ttaggaccac agaactcggt actaggaaaa ctcctatttt aaaatccagc 5520 cctgggtggg aagatttggg aagaatcgtt aatattgaga gagagaggga gaaagaggat 5580 tagatgagag tggcgcctcc gctcatgtcc gccccctccc cgcagagaat taccttttcc 5640 agggacggca ggaatgctac gcgtttaatg ggacacagcg cttcctggag agatacatct 5700 acaaccggga ggagttcgcg cgcttcgaca gcgacgtggg ggagttccgg gcggtgacgg 5760 agctggggcg gcctgctgcg gagtactgga acagccagaa ggacatcctg gaggagaagc 5820 gggcagtgcc ggacaggatg tgcagacaca actacgagct gggcgggccc atgaccctgc 5880 agcgccgagg tgagtgaggg ctttgggccg gcggtcccag ggcagccccg cgggcccgtg 5940 cccagggcgc aggagcagcc gggttggcct aagggacctt agtgccgggc ggaaagggga 6000 ctttgggttg gggattcatg gggggagccc atctggagct tgtcagggga gcgagcgcgg 6060 ggacctggac tgggctgagc atggagtgag gaggacgaga gcagagagac ccccgggact 6120 tcatcaggcc tggcagctga ctgcatgtgg ggtgaaaaaa ggaagccaca ggacagcgca 6180 caagggtatg gtgtggagat ggaggtggag atggcacagc aggccacaca gagaagaaac 6240 ctacagggag gtagctgggt ttgaggtgct tgaggggcag atgggtggtc tgatgggcag 6300 gtagacagaa gggtctgcag ccggggagga gactgagata catgagacca tccagggaga 6360 ggggacccag ggggaagagc aaaggaccgg atcctgggaa ctggacagtt gtgatttggc 6420 caagacagaa aagcctgtga aagagaccaa aaaaacccaa gtgcagtgtg aggagaggcc 6480 cgcagagaag agtcttggaa gctgagggga ggtgacctca gcagcacagt ggacagcggt 6540 gccagtgact tgggaaggtc agaaaacaga agatggaaag tgggtttgga aaccagggag 6600 acctggggag agcaggttgg ccgcagcggc aggagctgga atgggagggg gtgcatgagg 6660 ctgagtgtgg cgcatcctcc tcggggctga gatggatttt acttgtcttg ggttccccac 6720 ggctgtcaca gggcagtgtc tcagttcatt cgtctttttc cttcaggaag tctgggtgta 6780 aagggatgga gagaggtgag gtgtgtgcag taagaggatt tctcaaggat gggacaggaa 6840 ggccttggag ctttggcttc ctcctgtgaa cttgtggggt ggggagcctg gtgcaccaac 6900 ctgagggact tgagggagta gtatcaggat gtgggattga gccctggacc ttttttctag 6960 aaagaggaaa aaaatgaagg gaggaggagg aggaagctgg ggagatcaca cctttgattt 7020 tcttgttcct ggaaagtgaa aggaagttca cctgctatga gtgagaaggt ggacacactg 7080 ggtggggatg aggtgagtga catgagctta ggaaagttgc tgaggtaatt ggttgagaga 7140 ggtgttcaaa taaaaataac gcaattggca aaaactgtta ctaagacttt gtagaggcac 7200 caatcagtga catggcagca ttttctttca cagtaatcaa ctgccagatt gcagacagcc 7260 ctgatgccag cctaaggagt gtgggtttct cctccaggcc cgcaggtccc caacctcact 7320 cctctgaaga ctcttctgga gatcctctgt gatgcacaga tctccagact cagtgccccc 7380 agactcagat tccctgggtg gggaggtctg gggatctctg cttgtaatca gctccctaga 7440 ggttcccatg tagccagata agtattgtca gaacactgaa gatttttgaa aaatgaaaaa 7500 gagaaggttg gagatgtgtc ttcagaagac tactaagggt gctggctaga ggagggacca 7560 gaggcaggga gatgaggtag gaaactgcta ttatttgtca gggaaattgc aatcaaggca 7620 tgagttagaa cagggaaaac acagaggcaa gggagaggtg gaagggggag gaaagaagta 7680 gtgacaattc cagggtggat gtccacccaa atctagaagt aattgagcaa atgttttctg 7740 ggcattagag aaggcaacta gaacaaacag gaatccttgc cttggtgaaa tgtatttgaa 7800 ctgggtcaga aatgaggcca ttgggtatca ggccttaact ccagcgcacc ctggaggtca 7860 ctgatgtggc tccaggctga cctgctcctg tcaaagaata ttgagcaaga tgcctctcgt 7920 ggaatgttct gggaccttaa aacagatacc caagtattcc ccctgatttc atggttccca 7980 gaagctctat ggggaagaaa ttgtaggtaa ttcacaactg agatttagac ataagttgaa 8040 tagtgtaatg gacattgagt taaccgaggt aatgaagtag tgagacacag gtgcccctga 8100 aataaactca cattgaggga agaggctgac aatgtggatc agtctgaaaa caaggcaaaa 8160 atacaatagg gagtaagggt tgtgtgtcag ttcaagactg tacttttacc tggcccagcg 8220 ccatgttagg gtatttgtgt tctccaggaa gtagaaagga aagaactgag tgattaggga 8280 cctagaagac taatttgaga cattcctctt gatgagctgt tctctagggt agtcctctga 8340 aagagctgtt ctctagtgga tctccctgaa tgaactgttc tctaggagca cttgaccctt 8400 ttctgtgttt gttttttgtt ttgtgtttgt gtttgttttt gagacaggtt ctcactttgt 8460 ctcccaggct ggagtgctgt ggcaccatca tggctcactg cagcctcaac ctcctgggct 8520 caagtgatcc tcctgcctca gcctcccatg tagctagaac tacagataca cgtaccacca 8580 tgtctggcta atttattttt ctttttagag atgggttctc actatgttgc ccaggccggt 8640 ctcaaaaccc tgggctcaag tgatcctcat gcctcaacct cccaaagtgc taagattata 8700 ggcatgacca ccatgcctgg ccttttctgc tttctgagga ggaaaaaggt actggtggca 8760 gagatccaaa agaaaagttg ccagtggcag tgtggaaatt cacctgagaa caacaggaca 8820 agctggggca caaatgcaaa gatgcagagg gaggcaacac ctggtcatct gtgagacctt 8880 catgggacct gaagacgcag cacagaggag gaacttgaaa aaggacggga tttctactac 8940 tcaagcatgt aggagctcag gatattctgt aaatatgaag attttgagtt tttgtaggtg 9000 aggtaaaaaa atacataggt tttttacaga ataagacatg taaagctctc ttcattttct 9060 ttgtattttc atgaagttat tagattcaca ggccaccata atgccattgt ctgtatatct 9120 taatttcaag atattatttg agtaaatttt gcttcctttg tatcaagata gaactttgaa 9180 aaggtaggta atttcacagt tgatcaaata ttctttgccc aaattacttt tggttaaaat 9240 ttctcctaaa tgtgctacag agtgcaaact ctgtctccct gccattccgc tatatactta 9300 ctaactatta ttttattcaa gatcatgcat gctctacttg aaggtctatt tctatctttt 9360 caatgctacc cttacccact agcctaatca cattattcct attttcaaca tctaggaatc 9420 aattacatag tgaacatgcc taagaaataa taatctgggc agatgcagtg gctcaggccc 9480 gtaatcccag ccctttgaga ggccgagcgg gtggatcact tgaggtcagg cgttggtcaa 9540 gtgctcctag agaaccaggc tgaccaacat ggagaaacct tgtctctact aataatacaa 9600 aaattagcca ggtgaagtgg caggcaccta taatcccagc tattcgggag gctgaggaag 9660 gagaattggt tgaagcccgg aggtggaggt tgcagtgagc caatattgcg ccactgcatt 9720 ccagacttgg caacagagtg acactccatc tcaacaaaaa gaaagaatga aagaaagaaa 9780 gagcgagatt atgtctcaaa aaaaaggaag gaaggaagga aggaaggaag gaaggaagga 9840 aggaaggaag gaaagaagga caatctcaaa ttctatttca ttatttttct tccacgctcc 9900 tagtccagcc tagggtgaat gtttccccct ccaagaaggg gcccttgcag caccacaacc 9960 tgcttgtctg ccacgtgacg gatttctacc caggcagcat tcaagtccga tggttcctga 10020 atggacagga ggaaacagct ggggtcgtgt ccaccaacct gatccgtaat ggagactgga 10080 ccttccagat cctggtgatg ctggaaatga ccccccagca gggagatgtc tacacctgcc 10140 aagtggagca caccagcctg gatagtcctg tcaccgtgga gtggagtgag tctctgatga 10200 ccctctagac cccacctctg aagagcaggg gactctctgg ctctggggtc cactcatctt 10260 atcttctgca tctataccct ggggccatgt ccaaacccca tctttcttct ataccagctc 10320 ctgagcatag tttgaagcca gggaaatgga gacttcctga ccttggctta ggggttcctg 10380 aagattcata gttctccccc ttgtcagaga atctagggac actgactggt ctcgaaaccc 10440 tcacacttag gaactgacct cacacatagt aacagttctc ttccttcagc attttagcct 10500 cttctcaggc attttgagag gcaacttcca gaatcagcat ttgccacctt gttgaggtca 10560 cacccctgtt ccagatatga gggtggctct ttctgaattt cctcttagca agctttttcc 10620 gctgcactgt cctcatcccg atatgctgca tcaggctcca gaatctcaga caggacatga 10680 gtagggatgc agctggtgga ggtgacacta aacctgggtc tgtccttccc agaggcacag 10740 tctgattctg cccggagtaa gacattgacg ggagctgggg gcttcgtgct ggggctcatc 10800 atctgtggag tgggcatctt catgcacagg aggagcaaga aaggtgagaa agcctgcagg 10860 gtgagcggga cttaccttcc cctggcatat tcacacttat tccacgatga ggggtttgac 10920 agaaaagaaa tgtcagaaag ctctagaggc cactgatatc agataatcgg ggaacaaaca 10980 tgacctatag cgagagaggg atcccaggct gggatcttaa tgcagccaga tgcatgaggt 11040 cccaagtact caggctcctg cggagcgtcc attgagtgat gggcaatgga atttggtggg 11100 atggaaatgt ttctctaatt atctgaggtg gtttcaatgg ctgattatat aacctttcgt 11160 ctttcatttc agttcaacga ggatctgcat aaacaggtaa tattcctgct ttgatttcct 11220 tgtggggtgg gttgcaggag gatatgagtc ctttctgtgc attgtaacac tgaggctcct 11280 ccaggaaggg aatctcaggc atgaacccct ctttcaatgt cagccttcag gcaagtgggg 11340 aaagagcatt gcttggctcc attgctgaag gaagcagaga tcaactctgt tatttatcag 11400 cctgagacgc atcctctcac cataattttt ctctcctgga cttacaggaa ggaggctggc 11460 aacctgggat aacttgtctt ttacccccac agggttcctg agctcactga aaagactatt 11520 gtgccttagg aaaagcattt gctgtgtttc gttagcatct ggctccagga cagaccttca 11580 acttccaaat tggatactgc tgccaagaag ttgctctgaa gtcagtttct atcattctgc 11640 tctttgattc aaagcactgt ttctctcact gggcctccaa ccatgttccc ttcttcttag 11700 caccacaaat aatcaaaacc caacatgact gtttgttttc ctttaaaaat atgcaccaaa 11760 tcatctctca tcacttttct ctgagggttt tagtagacag taggagttaa taaagaagtt 11820 cattttggtt taaacatagg aaagaagaga accatgaaaa tggggatatg ttaactattg 11880 tataatgggg cctgttacac atgacactct tctgaattga ctgtatttca gtgagctgcc 11940 cccaaatcaa gtttagtgcc ctcatccatt tatgtctcag accactattc ttaactattc 12000 aatggtgagc agactgcaaa tctgcctgat aggacccata ttcccacagc actaattcaa 12060 catatacctt actgagagca tgttttatca ttaccattaa gaagttaaat gaacatcaga 12120 atttaaaatc ataaatataa tctaatacac tttaaccatt ttctttgtgt gccatcacaa 12180 atactcctta accaaatacg gcttggactt ttgaatgcat ccaatagacg tcatttgtcg 12240 tctaagtctg cattcatcca ccagcctagg cctcctgtct taattttcat acagacagaa 12300 atgactcccc actggggaaa gagcaaagca atacatgtag cactcttttt caaacactgg 12360 tctttttttt tttcttaaca atccaacatt gttatgtgtt ttgcgtctca tattgacacc 12420 ttttggtcaa ggtagaggac atgtttgttg taagctttct ttttcgtgta gaggatggat 12480 tcttcactcc tgatacacac aatcagtgca cagcagctct cttatacatc cagttgatgc 12540 cttcagtctc cctggcttct tacaagcatc ttctgggcct tgtgtgtccc tgggcacctg 12600 tccctggtca attcccgaaa gctactgtgc tcctcttgcc catctcccct tgcaaataat 12660 atcttccatc gggggaccgg cttcctccaa tttcaggaga ggtggggctg aaggcacaga 12720 cttgggcgtc actggcacag atataagtaa atacagctgg agtctgcaga gaggctggac 12780 tgagtcaggg agtcaggaaa gagaagccac acacaaggac aaccaatcat gtttctcata 12840 atcttcttaa cctagggaat aggacacaat cattttttct ttttaaaaca tctttatccc 12900 tgatcagcct catttcctca aaaactataa aggaaaatgc tgctgacttg tttttgcgta 12960 gtaatttcag ctgtcacata ataagctaag gaagacagta tatagtaaat aaggaccctt 13020 tatctgtctt attttccctt ttggcttcac aggaaacttg tgagaaacct atgcagcata 13080 aaattaatat gatttcaatc cagggattca acgatggaag gaggtcatga gaatagcaga 13140 aagtcttcaa atcgagatca ttatgaaatc ctcagaccca gagcacataa atcctaccct 13200 cagagtcact gagcagttaa cattacaaat tacaaaccat atccagtcag agtcattctc 13260 tttcctgctt gtctcctgta ctcatgttac aggttagggc agtaccccga gtggagtgaa 13320 caatctctgg actaacactt gtcaggatca gaagctgagg tatctgcacc cacattacag 13380 gaacaggata tgtgctccta gggaactgag ggtgtcagga gatgaggaat gtccctggag 13440 tcacagaaag aaggtatcag atgtgtctca ctctgacata tgcaggtgtt tatgaaactc 13500 tgggatttct aaggaaggat gcagtgcaga gacaggtccc agaggagac 13549 //