Dbfetch
ID LR813263; SV 1; linear; genomic DNA; STD; HUM; 10510 BP. XX AC LR813263; XX PR Project:PRJEB37962; XX DT 28-APR-2022 (Rel. 144, Created) DT 29-APR-2022 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens HLA-DRB1 gene for MHC class II antigen, allele DE HLA-DRB1*01:91QExtension XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Marsh GE S., Barker JOHN D.; RT ; RL Submitted (11-JUN-2020) to the INSDC. RL ANRI, HLA Informatics Group, Royal Free Hospital, London, NW3 2QG, NW3 2NU, RL United Kingdom XX DR MD5; 7f44beff11d7383dfcf0c6e73beef6f4. XX FH Key Location/Qualifiers FH FT source 1..10510 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /clone="AN00898" FT /db_xref="taxon:9606" FT CDS join(146..245,5518..5787,8017..8295,8997..9107,9595..9618, FT 10440..10453) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*01:91QExtension" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAC9884350.1" FT /translation="MVCLKLPGGSCMTALTVTLMVLSSPLALAGDTRPRFLWQLKFECH FT FFNGTERVRLLERCIYNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAV FT DTYCRHNYGVGESFTVQRRVEPKVTVYPSKTQPLQHHLLVCSVSGFYPGSIEVRWFRNG FT QEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSES FT AQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS" FT exon 146..245 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*01:91QExtension" FT /number=1 FT intron 246..5517 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*01:91QExtension" FT /number=1 FT exon 5518..5787 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*01:91QExtension" FT /number=2 FT intron 5788..8016 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*01:91QExtension" FT /number=2 FT exon 8017..8295 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*01:91QExtension" FT /number=3 FT intron 8296..8996 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*01:91QExtension" FT /number=3 FT exon 8997..9107 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*01:91QExtension" FT /number=4 FT intron 9108..9594 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*01:91QExtension" FT /number=4 FT exon 9595..9618 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*01:91QExtension" FT /number=5 FT intron 9619..10439 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*01:91QExtension" FT /number=5 FT exon 10440..10453 FT /gene="HLA-DRB1" FT /allele="HLA-DRB1*01:91QExtension" FT /number=6 XX SQ Sequence 10510 BP; 2797 A; 2077 C; 2532 G; 3104 T; 0 other; ctccaacacg agattaccca acccaggagc aaggaaatca gtaacttcct ccctataact 60 tggaatgtgg gtggaggggt tcatagttct ccctgagtga gacttgcctg cttctctggc 120 ccctggtcct gtcctgttct ccagcatggt gtgtctgaag ctccctggag gctcctgcat 180 gacagcgctg acagtgacac tgatggtgct gagctcccca ctggctttgg ctggggacac 240 ccgacgtaag tgcacattgc gggtgctgag ctactatggg gtggggaaaa tagggagttt 300 tgttaacatt gtgcccaggc catgtccctt aagaaattgt gacgttttct tcagagattg 360 cccatcttta tcattggatc ccaaattatt tcctccataa aaggagcttg ggtacttgcc 420 ctcttcatga gacttgtgta aggggccttt gcacaagtca tttcttttca aatctccacc 480 aataaaacct ttgcatcaca tgtcctcagg gtctttagag gatttagaaa taaggattct 540 aaaataaatt ccccatacag cacttccctt tattatgttg acttatgtca gacaaaagga 600 ggttcttact gaaaattttg tgggagtcaa gggaattcaa agggtctctc ctagacgatc 660 cagtgttagg ttccccacag gacctttggt gttggccata gtcctcatat gtgaggatgg 720 acccagtggc ctccccatta tctcctttct tttcttgctg aactccaatg tttataaggc 780 ctgtatccct gtagcgtatg taggttctct gacagaagtt atacttagtg ctcttccttt 840 cttgtgggga aaagtccctg gaactgaagc tgagattgtt agtacttgga gtcaccttac 900 agatacagag catttatgag gtattctttg gtgcctaaag aacttaaggc atcctctgaa 960 aaactagccc aggttcgtgt tcattatgaa tcttttttaa cctttctgta cttgtttctc 1020 ttgcatctcc tatgtgctct aactagacat gacagaagag atttaactaa tgtataaatt 1080 atatgaaatt ctatttttta agtcaaaaat aatcaactat cagaaattta ataatgttca 1140 aactatatac tctgtgtggg gttaccgaga tgatgtgaac attgttcacg tctcataggg 1200 ctgaaagtca atgggcaagt cttgggaact cattgtctta ctggggtctt gtcctaaatt 1260 tcctaggttc acccatcatg ccctcagctt tccttaacta gccatgtctg cttacctctt 1320 cctccagttt ctatttttcc ccagctatgt tgtcatcatt tccagaaatc tctaaagctt 1380 gcacagaacc ttagcactat gcgattcatt gaaagagact ttttttctct ttttgaggta 1440 gggcctggct ctgtcaccca gtctatagct cagtggtgtg atcgaggctc actgcaacct 1500 ctgccaccca tgctcaagtg atcctccctc ctcaggctcc agagtagctg ggaatacagg 1560 caggcaacca cgcccagcta atttttgtaa ttttggtaga catgagattt tgccatgttg 1620 cccaggctgg tcttaaactg ctggtttcaa gcaatcctcc tgccttggcc tcccaacatg 1680 ctaggattat agatgtgagc cactgtgccc aggcaaaaag aaatgactct taataaaaaa 1740 atttcctttt tcttaaatca ctgtttcttt atctgtgaat tcttcttcca actagaagga 1800 ggagaaaaaa gaagtttgcc tgtatttctc accaggagga gaaggggtct agtgtgacat 1860 taaaatgaaa gggtgctgga gcttgagccc cttcttgctt tccaggatcc ctacagtgat 1920 cagttcccat accctggttt attcatgtaa accacactta tttttctcag cagctactct 1980 ttactgggct ccattctagg ttcaaatcat tctatttgat taagttagag agcgtcccta 2040 ctctcatgga agttacacaa gagtagagga gacagacact aacccaataa gcatttaaca 2100 aagaagataa tgttagagag tcatagtgca ctgaagaaaa gacatcaggt ttgtgaaaaa 2160 gagagacatg gattcaccta ctttagttca tatgttaggg agctccacct gagaaagtga 2220 cattcagctg agacaacaaa ataagtagac agtcgtgaag atctaaggga tgaaagttcc 2280 agggagacca aatggcggga aagccctggt gtgggaaact atgtggaggg agagaaagaa 2340 agctagaggg gctgaagtat agaaagcaac gaaatggaga ggcagaagat gaggtaggac 2400 acagagagga agtcaggagc ctcatcatta taggctctga tgtccacggt aaaaaaaatt 2460 tgaattttat tatttattta cctatttatt tgtttattta ttttatttta ttttgtgatg 2520 gagtctctct ctgttgccca ggctagatgg cagtggcaca atctcggctc actgcaacct 2580 ccgcctcctg ggttcaagca attctcctgc ctcagcctcc caattagctg gggccacagg 2640 tgcatgccac cacacctggc taattttttg tatttttagt agggatagga tttcaccgtg 2700 ttagccagga tggtctcgat ctcctgacct cgtgatccgc ccgccttggc ctcccaaagt 2760 gctgggatta taggcgtgag ccactgcacc cggcctatat tcaattttta aaactaattc 2820 tagctactct gtggggattg gattgttggg gttcaccagt ggttaggaag actatttagg 2880 agcacagcag ggaattctcc agggaaaaca agcttgtggc ttcatggagt gcattagtga 2940 taaagacggt gaagaagata aagtggacag actcggcatg tatttttgct tagcttgtta 3000 atgaattact gtaaaggggg tagagcttat tcctaaggat tttcttttga caaataagtg 3060 ggtggtagtg ttgtttattg agataggaaa aactatggga ggaaatgatt tgaagtgggt 3120 ggtttgaaat aaaagttttg tttaaatatg agatgattga ctgacattta tgtggagcaa 3180 tcagaaggtc aatggcattt aagagactca tggtgaggct agggcttcag gtatttatgt 3240 tggaggcatc aatacgtgta gtgtgttaaa ttccagggag tggaagagga tacataggga 3300 gatggattgt gtggagaaac aagaagaggg cacaggccag caaagggggc tgagaaagag 3360 cccagggatg ttggagaaaa accaagagaa catcatgtat gtaagtcaag gaaaacagat 3420 ttttttcaag gagaagggag aggccaattg tggtgagtac cactaagagg agggggaagt 3480 gagaatatga cagagaagca agtgctggga ttggtggagt tgatatttgc agtcaatgga 3540 gtatccaggg aggaaactgg attggaccat ttggagagca aataaaagtg aggacgaggt 3600 taaggttgac tgttctgtgt agagagcttc agggaaggat tgttctctgg gttcagggag 3660 ccagctgaac ctaaaggaaa aggctaaaga agctgaagag aaggaggagg acctgtgaac 3720 cagagatgct cagccattat tagcaaggaa atacaagaga gcccctgtgt gcagtggtga 3780 ctactcatgc aaaatgtcac acagccaata tttaacacag ccaggatttc acacagccaa 3840 tatttattag tgacatagaa tatatttgtt attgctctag gtcatgagaa tggagtgaca 3900 aaatgaatcc ggtcgccatc agtatatgcc acataacatt ttgcagtgac tgtgtgccag 3960 gcctatgaat ttcagtattc aatttcaata atgatcctgt tgtatctgtg gtatttaaaa 4020 acatatacat ctctgtaatc taaaattgag aggttataag taaaacccag tattacaaat 4080 ttagtgctgg aaattgattg cagtttaaat ctgagcatat agaaagtccc tttcttctat 4140 gtcagcagat gccttttgtg tgaggtttag gtatactgca ttattagaca taaaccagtg 4200 tttctgccct atgttttcag aatgacaatt ctttatgaaa ctaatagaag aacagaagac 4260 aattgcaaaa tcatgatgaa gatactaatt gctttagaat taaggaatac aaataatgtg 4320 agctgcagtt atagggatca aaaaagttac aatgggaatg tatttgagtg tttattatgt 4380 gatcagtgct aagaagtgtc atcatttaat tttacactta acagtaatcc tgtgaggatt 4440 atgctattat taaatgcact tgatacatta caaaaaggct tatggttgat ataaattgac 4500 ccaagtagaa gagatcatgt ttttattcag gttttctgat tctagagttt gagagtttga 4560 ccatcattag tgagtagtga ctatattgtg tctgaattat tgacagaatt tctgatattc 4620 atatgtacca ggttgtttct tagagtggga gcagagatgc aagggctgct agttccgatg 4680 tgtaggagaa actatcattc attttgcatt tatcatttta aacgttctat atgtctatcc 4740 tgggcatgtg ttgaagaaca caaggaagta ttaaatcact ccttcttctg aagtttgact 4800 ggcaaaattg ggctagagtt acgaaataaa atacaggttc ctagtgaaat ctgaatttca 4860 gatacacaac cataatttat tggaaatcca aatttaactg gatatcttct attattctct 4920 gttctagaac tccacacttc taacatttct cattcctgtc taagctcttg tgtgtttggt 4980 ttttggccat cgctttcact gctctttaag ctcccccagt agagtggaga ggtctgtttt 5040 ccctcgtttg gattcctaca ggcagcgcag gcctggcaca aggtcatcac taaggaagtg 5100 ttcacagggt gaaggcggtg ggtgctgttg aaggaaccgg taaagcctgt gggatgagag 5160 aaggagcaga gagtgttttt ggggtggagg ctcccaggag gaggcgggac gggctgcggt 5220 gctgggcgga tcctcctcca gctcctgctt ggaggtctcc agaacaggct ggaggcaggg 5280 agggggtccc aaaagcctgg ggatgagaag gggttttccc gcatggtccc ccaggccccc 5340 gttcgcctca ggaagacgga ggatgagctc ctgggctgct ggtggtgggc gttgcgggtg 5400 gggccggtta aggttcccag tgcccgcacc ctgcccaggg agccccggat ggtggcgtcg 5460 ctgtcagtgt cttctcagga ggctgcccgt gtgaccggat ccttcgtgtc cccacagcac 5520 gtttcttgtg gcagcttaag tttgaatgtc atttcttcaa tgggacggag cgggtgcggt 5580 tgctggaaag atgcatctat aaccaagagg agtccgtgcg cttcgacagc gacgtggggg 5640 agtaccgggc ggtgacggag ctggggcggc ctgatgccga gtactggaac agccagaagg 5700 acctcctgga gcagaggcgg gccgcggtgg acacctactg cagacacaac tacggggttg 5760 gtgagagctt cacagtgcag cggcgaggtg agcgcggcgc ggggcggggc ctgagtccct 5820 gtaagcggag aatctgagtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgta agaaagagag 5880 agagcgcgcc atctgtgagc atttagaatc ctctcaatcc ccagcaagca gttctgagag 5940 cacaggtgtg tgtgtagagt gtggatttgt ctgggtatgt ctgttgtggg aggggaggca 6000 ggagggggct gattcttatc cttggagacc tctgtgggga ggtgacaagg gaggtgggtg 6060 ctgggggctg gagagagagg agaccttgat tgtctcgggt ccttagagat gcggggaagg 6120 gaaatgtaag gggtgtgtga ttggggtgaa ggtttagggg aggactgctg aggggtaagg 6180 aaggtttggg ataatgtgag gaggccggtt ccagactctc cctggcatac acccttcgtg 6240 taatctctga aataaaagtg tgtgctgttt gtttgtaaaa gcattagatt aatttctaga 6300 ggaactgagt agacctctga ggcactcctg aagcttcttt atatctaaat ttcttgctag 6360 ttttttgggt ttttttagtg tgtatatttt tacatagtag aaatgactgt gaaactaact 6420 ttttgaatta aagttttaac acagttacta ttttattata atgctagttt tctagtagtt 6480 acatattatt cttttatata taatagttat gacacaactc acctcacttt cccctttgtt 6540 gacctttatt atgacattca ccaaaagttg aaaatgtatg tttctggtta atttttaatt 6600 tatatttttt atttgtaatt gctttgaatt attttgacct atttattggc ggattataat 6660 tattgctcta agaattccct attgtatttg gtaggcaatg gacaatgatc tatggtctga 6720 tatcttgagg gcttagtatt tttctcagtg actttgtggg ttctttgtgc tataagatta 6780 ttaacacttt attgatattt gatccagcat ttgcttcagt ttgtggtttg tatgtggatt 6840 ttgaaagttc ttttccatgt taagaatttg aactttttat ttaataaaat atattgcaaa 6900 atttttatta atgatttaca atccatctta aatctgccat tttgtggcat tgttgtctcc 6960 aggttcctcc ttacttctaa aaaaaatagt tgtatttatt gagagtatgc tagtgttggg 7020 gattttcctg ggcataagca ccccaagtaa caagtcccag acactgcctt aatccaaatg 7080 tgactctgga aagaaaaatc attttacaat gataggccta ataataatta tgcttgtgtt 7140 acacgggaga tgcattgatc agctaaatgt aaatataaga actttcaaaa ctaaaatgac 7200 attccctaat ccttttctct gcttcgggac tcatgctttt ctaggaacgt aaaaatttgg 7260 agaatcattt ctgtctgtcc cacattccca ggggcagaac aatttctgtt ttgttctaag 7320 gtgtgagtgc atggcagtag tattcctaaa attcatactc ggtttcctca tgtacccaat 7380 tctgtccctt tatctatgca tatttcttta aatcatattt ttctgtcatg gggtacaagg 7440 atgataaata ggtgccaagt ggagcaccca agtgtgatga gcgccctcac agtggaatgg 7500 agtgagaagc tttctgacct tataaactga aggctatctt cagtcattgt tttatatatt 7560 ttacatgcat taatcctcat ataaccccaa gaggtaaatt agtataatta tccttcattg 7620 taggtgacaa agttgagaca cagaagaatc aaaaaactct tccaggatca accagtaaaa 7680 ggcagacctt ggattcgaac caagcaacct ggctcaaata tcagttttaa ttactacact 7740 ctatactttc caagatttgt aaacagtttg acaatgcatg ccaatttaaa gctatgaaga 7800 aacaaacaca atttttcaca acacctctca aatctaatgg gtcctcactg tcaagattaa 7860 attccaggct gatgacactg taaggtcaca tggccagctg tgctataggc ctggtcaagg 7920 tcagagcctg ggtttgcaga gaagcagaca cacagccaaa ccaggagact tactctgtct 7980 tcctgactca ttctctctac atttgttttc tcctagttga gcctaaggtg actgtgtatc 8040 cttcaaagac ccagcccctg cagcaccacc tcctggtctg ctctgtgagt ggtttctatc 8100 caggcagcat tgaagtcagg tggttccgga acggccagga agagaaggct ggggtggtgt 8160 ccacaggcct gatccagaat ggagattgga ccttccagac cctggtgatg ctggaaacag 8220 ttcctcggag tggagaggtt tacacctgcc aagtggagca cccaagtgtg acgagccctc 8280 tcacagtgga atggagtgag cagctttctg acttcataaa tttctcaccc accaagaagg 8340 ggactgtgct aatccctgag tgtcaggttt ctcctctccc acaccctatt ttcatttgct 8400 ccatgttctc atctccatca gcacaggtca ctgggggtag ccctgtaggt gtttctagaa 8460 acacctgtac ctcctggaga agcagtctca cctgccaggc aggagagact gtccctcttt 8520 tgaacctccc catgatttcg caggtcaggg tcacccactc tccccaggct ccaggccctg 8580 cttctgggtc tgagactgag tttctggtgc tgttgctctg agttattttt tgtgatctgg 8640 gaagaggaga agtgtagggg cctacctgac atgaggggaa tccaatctca gccctgcctt 8700 ttattagctc tgtcactcta gacaaactac ttagcttcat tgagtctcag gctttctgtt 8760 gatcagatgt tgaacgcttg ccttacatca aggctgtaat atttgaatga gtttgatgtc 8820 tgaacatcgt aactgttcag cgtgatttga aatccttttt ttctcctgaa atggctagtt 8880 attttaattc ttgtggggca ggcttctgcc ccattttcaa agctctgaat cttagagtct 8940 caattaaaga ggttcaattt ggaataagca tcactaaacc tggattcctc tctcaggagc 9000 acggtctgaa tctgcacaga gcaagatgct gagtggagtc gggggcttcg tgctgggcct 9060 gctcttcctt ggggccgggc tgttcatcta cttcaggaat cagaaaggtg aggagccttt 9120 gggagctgac tctctccata ggcttttctg gaggaggaac catggttttg ctgagaggtt 9180 agttctcagt atacgagtgg ccctgaataa agcctttctt tccccaaacg gctctaatgt 9240 cctgctaatc cagaaatcat cagtgcatgg ttactatgtc aaagcataat agcttgtggc 9300 ctgcagagac aagaggaagg ttaacaagta ggggtccttt tgtttgagat cctggagcaa 9360 attaaggaag agccactaag gctaatggaa ttacactgga tcctgtgaca gacacttcag 9420 gcttcatggg tcacatggtc tgtctctgct cctttctgcc cctttctgcc ctggttggtg 9480 cgggttgtgg tgttagagaa atctcaggtg ggagatctgc ggctgggaca ttgtgttgga 9540 ggacagattt gcttcaataa cttttaagtg tatttctttt cctctttttc ccaggacact 9600 ctggacttca gccaacaggt aatacctttt aatcctcttt tagaaacaga cacagtttcc 9660 ctagtgagag gtgaagccag ctggacttct gggtggggtg gggacttgga gaacttttct 9720 tacaagaggt ttctaaatgc cccaatcagt gctttgtaaa aacacaccaa taggttctct 9780 gtggctagct ggatgtttgt aaaatggacc aatttgcact ctgtaaaatg gaccaatcag 9840 cattctttaa aatggaccaa tcagcacttt taaaatgggc caatcagcac tctttaaaat 9900 ggaccaatca gcactcttta aaatggacca atctgcagga catgggcagg gacaaataca 9960 ggaataaaag ctggccaccc caaccagcag tggcaaccca ctcaggtcct cttccctgct 10020 gtggaagttt tgttcttttg atcttcacaa taaatcttgc tgctgcctac tctttgggtc 10080 cctgccgcct ttaagagctg taacactcac tgtgaaggtc tgcttgaagt cagcgagacc 10140 acaaacccac tggaaggaac aaactgcgga cacactagaa tgatggtaga ggtgataagg 10200 catgagacag aaataatagg aaagactttg gatccaaatt tctgatcagg caatttacac 10260 caaaattcct cctctccact tagaaaaggg ctgtgctctg cgggactatt ggctcagggg 10320 agactcagga acttgttttt ctgcttcctg cagtgctctc atctgagccc ttgaaagagg 10380 agaaaagaaa ctgttagtag agccaggttg aaaacaacac tctcctctgt cttttgcagg 10440 attcctgagc tgaaatgcag atgaccacat tcaaggaaga accttctgtc ccagctttgc 10500 agaatgaaaa 10510 //