Dbfetch
ID LC257890; SV 1; linear; genomic DNA; STD; HUM; 9676 BP. XX AC LC257890; XX DT 26-MAR-2019 (Rel. 140, Created) DT 26-MAR-2019 (Rel. 140, Last updated, Version 1) XX DE Homo sapiens HLA-DPA1 gene for HLA class II histocompatibility antigen DP DE alpha chain precursor, complete cds, allele: DPA1*02:02:02:02. XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-9676 RA Shiina T., Suzuki S.; RT ; RL Submitted (10-APR-2017) to the INSDC. RL Contact:Takashi Shiina Tokai University School of Medicine, Molecular Life RL Science; Shimokasuya 143, Isehara, Kanagawa 259-1143, Japan XX RN [2] RC Publication Status: Online-Only DOI:10.3389/fimmu.2018.02294 RX DOI; .3389/fimmu.2018.02294. RX PUBMED; 30337930. RA Suzuki S., Ranade S., Osaki K., Ito S., Shigenari A., Ohnuki Y., Oka A., RA Masuya A., Harting J., Baybayan P., Kitazume M., Sunaga J., Morishima S., RA Morishima Y., Inoko H., Kulski J.K., Shiina T.; RT "Reference Grade Characterization of Polymorphisms in Full-Length HLA Class RT I and II Genes With Short-Read Sequencing on the ION PGM System and RT Long-Reads Generated by Single Molecule, Real-Time Sequencing on the PacBio RT Platform"; RL Front Immunol 9:2294-2294(2018). XX DR MD5; 56e902cbfe8133230f522ad9fffcadcb. XX FH Key Location/Qualifiers FH FT source 1..9676 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT CDS join(226..325,3892..4137,4478..4759,4974..5128) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DPA1" FT /allele="DPA1*02:02:02:02" FT /product="HLA class II histocompatibility antigen DP alpha FT chain precursor" FT /db_xref="GOA:I2G9G1" FT /db_xref="InterPro:IPR001003" FT /db_xref="InterPro:IPR003006" FT /db_xref="InterPro:IPR003597" FT /db_xref="InterPro:IPR007110" FT /db_xref="InterPro:IPR011162" FT /db_xref="InterPro:IPR013783" FT /db_xref="InterPro:IPR014745" FT /db_xref="InterPro:IPR036179" FT /db_xref="PDB:3WEX" FT /db_xref="UniProtKB/TrEMBL:I2G9G1" FT /protein_id="BBD34208.1" FT /translation="MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAMFVQ FT THRPTGEFMFEFDEDEQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTL FT IQRSNHTQAANDPPEVTVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGV FT AESLFLPRTDYSFHKFHYLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQMPETTE FT TVLCALGLVLGLVGIIVGTVLIIKSLRSGHDPRAQGPL" XX SQ Sequence 9676 BP; 2647 A; 2106 C; 1871 G; 3052 T; 0 other; aaattctccc atctcttccc cagcaccttc cagcgtcctc tttacccagc aacagagaat 60 gtcagctcta tgatttctct gataggtgaa tcccagccat gctgattcct ctccacccat 120 ttccagtgct agaggcccac agtttcagtc tcatctgcct ccactcggcc tcagttcctc 180 atcactgttc ctgtgctcac agtcatcaat tatagacccc acaacatgcg ccctgaagac 240 agaatgttcc atatcagagc tgtgatcttg agagccctct ccttggcttt cctgctgagt 300 ctccgaggag ctggggccat caagggtgag tgctcaggag gacgcaagag cgtcggggtg 360 agtgatgggg tggttcacat caattgttgc ttcaggaatc acagatttta ggggctcatt 420 gatctatctg gtcctcatag tctatgttcc ctctggccct cataataata acagcaataa 480 cagccagaat ttatgagacg cctgcatagt ttctttcccc atttacatct cacaggaacc 540 ttcaatgaag ataatattcc attcatttag aaattattcc ttttatttag aaattatttt 600 gaaaaaactg aagctcaaaa agatgaataa gttttccaag gttacacagc agatcaacga 660 gccaagtttg aagtccagac ccagctctga gggtcgtaca ctgccttccc cagattcctg 720 cacacagtga cctactacca gggccctcct atctctctgg gatccccagc ctctgtcttt 780 tgtggctgct tcacaggaac tccgagctat ggactctgca ttaggagagg aagtgcgaag 840 agtgtttctg tatcctctct ctcttctagg accctagggc tcttcctggg tctttgtggg 900 tggtcacaag ctttcctctc tcaagacagc agggttgcat ggtcttgata gccttgtgat 960 tcgggttctg agagatccag gactgcaagg gaggcctaga cttttgatag ctgcaaggac 1020 tcagccagag atggaccgta gtgaatgctc ctttttcctg tagctgaaat cagggagaat 1080 gacatcaagc ctgtgcatga tgctgtcatt ccaaaatcta gtgatgggga aggttagaat 1140 ccataacgta caagatgcac actggcttca gacagtttta tttaagatgt gtagaataaa 1200 gaggaggtca ggctgggtag aaccagaagt atctattgcc ctgttcgcgg tcacctgagt 1260 tatttttaat gttatgttat aataaacacc acaataggct tctcttcata gatgcaaata 1320 ctttttagta ttcttggtag aaattcctaa tgagctcagc tgtctcttca gggcttccct 1380 gcccagtggt tccttgtctc ttaacattta aacatgtaat ttaccttaaa aacataagtg 1440 caaatcaact gataaaaaac aaccttgcct tcagtctgca tcctatccca gagacacttt 1500 ctttgtgtcc tcacacgtgg agctaagctt ctgacttgtc tctggtacat ccctgaggat 1560 cctctcatct tggccatcag gaacctctac agaaggtcaa atccagtggg ttcttctcag 1620 tgcccctgac ttgagttact aataacattt gcactgtaat ccacttcttt ctgatgaact 1680 accgtgtcct tatttttctc ctgtttacct ggatcctcct tatcatcctt taaatcacct 1740 cttaattatc atgttctctc attataccct gagatctcag caattctgat ttttggcact 1800 cttcctggaa aatctcattt aacctgtgcc tgccactaat gactctcagt tctctggcct 1860 aaactcctct cctgagacca cccataatcc acaaatgtct atgtattatt tctccttaga 1920 tgactttcag gtcttctaag tgcaatagcc ccacagtgaa ctcagtatct tctcccagtc 1980 aggctgtctt ccccctgaga gaagtggctt ttgccctgtt ttctgaatgc ctacattgaa 2040 gccatctgtt ccccaggaag ccttccctga tgtgctgctt gatcgcatct tgtgtatacc 2100 cacgtatctg cacttatcct tctgaacctg ctgttgtctt gtcacttgtg tttccttctg 2160 tgacttatac gcgtctgcac aacaggacgt atgtattatt tttatttgag tatttagcat 2220 ctaacagtgt ttgacatata gtagtctttt aatacatatt tttgtctgaa tggaaatgat 2280 attttgaagt aaaataatct gttccatagc tggctgatct ttggactgca gaacttgtga 2340 aagtgttttt taaaaagcat tttaaaaagt acaagggaca ttcatgtatt aagaagatga 2400 gttttcaata actgctagag gactttgtgt ctttttatat taccctcttt ttcctgatga 2460 gtcctttgag tcctttaaac tgaggagcaa gctaagtttc ctagtgaaat acctatagga 2520 tttgttttgt ttagtttcaa ataccactct ttgcttggcc acttactgtg tcagggagtc 2580 attctcagtg aaaaataaga cacagatcat accctctaga cacttacaat tacagtgaca 2640 aggagtcatt ctcctgtccc cacatgtcag ggctgaaaac tcacagggaa atccgtgagt 2700 tgggaagtga gagcagaaga gctccatagt tccttctcac tctgatgcat ttatcattct 2760 aaacccagac tttcacatac acattcatca ttttctttca tgataatagt tgcttttatc 2820 ctcttatctt tgctaattct tacaaactaa taaagactaa gaaacaaaat aaattaaatc 2880 ctacaggtgt tccaaactca gcaataattt ctagttggcc tctaaaacaa aaatcaaaat 2940 ataaatgtaa gaaaagttca gaatgcttag tacctgcgtg atgaaataat ctgtacacta 3000 aacccccgaa tcatgagttt acctatacaa caaacctgca catgtactcc tgaacataaa 3060 ataaatgttg aaatattttt aaaaaggaaa caaaagtttg gaacaaatgc caaaataact 3120 gtactgtact tttgaattta tatgccccaa atgaaaaata ttatcaacaa agctatacat 3180 tctacatttt catgttcata aactaagaca gaaactttaa aactgtcaag agcactaaaa 3240 tttgaaggat attttcttct tcctctcaat ttcgtatttt tttctacctt ttctataata 3300 agaaaaagaa aatgtccact ctcccaaccc cacgactcta aaaacaattt tacatctgtg 3360 tcctagaaga attaagaact taatgggata gaaaacctct ctactagttc caccagtagc 3420 cgtatgacct tagcaagtta ttaatatgta acttccctgc atttccttac ctgtaaaatg 3480 tatgatatgt atttgcttca taaagttatt gtgacaattc aacgagtgaa tatgtaaagt 3540 atttagaagg atgcctggca caactaagtg ctcaacaaat gttagctgtc attgttacta 3600 ttactattgt gtagggtcag gatgcccaga ctttcaaaga ccaggaagca gcttgactta 3660 tcaatgataa actttttatt ttgttcttca ctcctttctt tttataactg ctcatctgct 3720 ctgtattatt tcctttatgg tgttgctcct tcttcttccc catatgtcct tcctttgacc 3780 tcttactttc ttccttttta tattcataag tctttattca ttctctagct ttgaccactt 3840 gcatattcaa actgacattt tgtcatgttt ttctctactt tctttatgca gcggaccatg 3900 tgtcaactta tgccatgttt gtacagaccc atagaccaac aggagagttt atgtttgaat 3960 ttgatgaaga tgagcagttc tatgtggatc tggacaagaa ggagaccgtc tggcatctgg 4020 aggagtttgg ccgagccttt tcctttgagg ctcagggcgg gctggctaac attgctatat 4080 tgaacaacaa cttgaatacc ttgatccagc gttccaacca cactcaggcc gccaatggta 4140 ctgcctatct ttgcctcttc ctctgtagcc caactggaag ggatgagagg gcctctctgc 4200 caccctcaga ctaggaagcc taagtgcccc ctgctgtgtg atcctcttcc actagtggcc 4260 gtgggctgat cccaccacag caagggcttt catcctctct tctcaggaga gagaaaggtg 4320 agcagagtga ggctggtcag tggtgtgata cccctctctg tgattcacag ctgccataaa 4380 atctaaggct gaggtagagg accaccctcc cccaagaggt ggagcctttg tgattcatcc 4440 cagaagaggg acctaacctg gtgctgtctc ctcctagatc cccctgaggt gacggtgttt 4500 cccaaggagc ctgtggagct gggccagccc aacaccctca tctgccacat tgacaggttc 4560 ttcccaccag tgctcaatgt cacatggctg tgcaatgggg agccggtcac tgagggtgtc 4620 gctgagagcc tcttcctgcc cagaacagat tacagcttcc acaagttcca ttacctgacc 4680 tttgtgccct cagcagagga cgtctatgac tgcagggtgg agcactgggg cttggaccag 4740 ccgctcctca agcactgggg tatgcaactg cttttctctc cataatctcc tggcatcctc 4800 tattccaaag acctggtgtc ctctgcacca gctttcccca ctggccaggt ctcagtcctc 4860 tcctcgtcct aacatccaat taactggtcc ataaccttca attcccacaa ccatcccagg 4920 ccagaaccac cctcactaca cctcctgacc ctatctcttc attcttcccc cagaggccca 4980 agagccaatc cagatgcctg agacaacgga gactgtgctc tgtgccctgg gcctggtgct 5040 gggcctagtg ggcatcatcg tgggcaccgt cctcatcata aagtctctgc gttctggcca 5100 tgacccccgg gcccaggggc ccctgtgaaa tactgtaaag gtgggaatgt aaaaaaggag 5160 gtcctagaat ttgtagaatg taaggaaggg aggaaaaatt caatctgata agtgttcatt 5220 gatcttctaa tgggttagaa gcactcagcc acataacaac aacaacattg ataactaact 5280 gagtagttaa tatggtcagg cgctattctg agggtttaca ttcattaact cactttattc 5340 tcacaaatag tctttgaggt aggtactatt attttcacca tttcacatga gagatactta 5400 catcttttta catacacaga gatcttaagc actttgatcc agttcccaca gctatgaagt 5460 agtagggcta ccttccaatc cagaaagtct ggatccaaga ctgtttatcc actgtcctat 5520 tcaccctatt ttgtgaagga aaagaccaag ttgaaattct ccaagagtcc gttgtctaat 5580 aacggagcca gatctatatt tctatacata attacaacac agtgtggtgg gagcctgtaa 5640 ctacttactg tctctacttg gactcattcg atggcaatgc tcacacaaaa aatgcccctc 5700 ctgagatctt ataggtttct atttatcgta acactcacca tgctttatat ttttatatgt 5760 tttgggaatt ctcttagcat tagacggtga acttccatgc agatgaccac atctaattca 5820 ttattattat tgttattcat gctggacctc aggtacaaaa ggttaagaac ttctcagttc 5880 attatactgt aatcactggt gcctccgaac tctctctctc tctcgattta tttggtcctt 5940 tttatctcca gtccttactc ccatatctaa cctcttaccc ctacctcata ggtaaacatt 6000 ttaatgaatt tgatgtttcc ttttatttgc atagatgctc cctaatatgt agtagtgtcc 6060 agtgtacatg tatttttaat taaccaaaat ggcattaaat tatagatctg attttgtata 6120 tccagtttgt ttcttccaaa tcttccatag tattttcctc tatatgtcca tgcattagtc 6180 cattttgcat tcctataaag gaataaagga atatctgaag ttacctaatt tatgaagaaa 6240 agagcttcaa atggcttaca gatctgcagg ctgtccatga aacatggcac cagcatctgc 6300 ttctgttggg ggattctgga agcttttact catggtggaa ggcaagtgga gccagtgcat 6360 cacatggtca tagagggaga aagagacata gaaagaggtg ccaggctctt ttaacaacga 6420 ggtttcacgt gcactaatag agtgagaact cactcattac cctggggcgg gcaccaagcc 6480 attcatgagg gagtctcctc catgattcaa atacctccca ccaggcccca cctgcaacac 6540 tgggtatcaa ttttcaacat gagatttgga agggacaaat atccaaatca tattaatcca 6600 catatctata ttgctcctgg gatacctgga tcacccctgg ttctctacta ttgcaagcga 6660 tgctcgtatc tcacatggaa ctgcatatgc atgtgggcct gacctgcatc cctggaatgt 6720 atgtatccta gaaaggggtt gcagggttgc tggagatgca gctccttaat ttgactaaat 6780 actgctcatc ttctcatcag aatggctgta ctcatctgtg cttcctttgt cagtacctga 6840 aatgtcctgc aactcctaaa tgcacatcaa cactggacat tatccagttt tctaactttt 6900 gccaatttca tttgcataaa gaaatatgct gttttatttt gcatttcttt aattactaat 6960 aattggggct ataattagga ctgattaacc acttgggggt tccttttcta taaattgcct 7020 gttcacattc attgcccatt tttgtattat gtgcttctat cattttctta ttgatttgca 7080 agtgatactt atacagtcct gctagtagtc ccttgtcagt tttaggcatt gcaaatgttt 7140 tcccctaatc tgacttctgg taactttctc cttggtttcc tttattgaag agaaatcctt 7200 aatattttgt gttgaagtcc atcaactgta tttttgttta tgcatctttt ttaaaagaaa 7260 tcttccctgt actgagatat caaagatact cttaaaacat ctcctacagt tttaaatttc 7320 acatgtacta ctttaattca tttgggattc atctttgtgt ttgatgggga tcatgtttta 7380 tttttctcta tataatggtc cagtgtgttc ccacaactac taaatagttc accttttccc 7440 cataagctag tggtgtctcc tttgctatac tgaaagctcc cattacagat gggcctgtgt 7500 ctgagttcca tcttgttcca ctgttctgtt tgtctcttct tgtgccagtg tcctagtgtt 7560 ttgattacta tgacattgta gtgtgtgtta gtatccagta ggaaaaattc ttctttattt 7620 ttctttgttc acacacattt ataatgatat ctataatgat ttgtaacaga atgaagtgaa 7680 tgtagaatgt cagatgttaa gaggaagaat ggaaaggagg gctgggacta gggtgatgta 7740 ggggatgcac ttggcttagg tgcaaaattt gggagatgcc aaaagaactc agtaataaat 7800 catattttaa tgaaatatct tgaaaaagca aaattaatgc aaagatacat gattaacaaa 7860 atatcaaaag aggattattc aacgaaaatg gagaagaagc agagaggcag aataattagg 7920 agaatatgtt gtcacataag ccaaggaatt aaagaattcc aggaaggagg aagtactgct 7980 gtcagatgtt caacagaggt cattttagaa aatttacctt ggttttgaaa tcctttcaaa 8040 gagcagttta cacaatgtga acaagtatcc ttccttcatt gccatcattg atatggtttg 8100 gatatttgtc ccttccaatt ctcattccag ggttaagctt cttctcttcc ctcagtaatg 8160 tggcccttcc ccttgtcagg atattttgga gacatgaagc atgtgggatg ccctcaaagt 8220 cagctggggt ttgagggtga aattcaatga ctttcgtgaa ctccttggct cctatgtgct 8280 gttcacctgg aggaccaggg tttgtgcagg gatgaccacc ttctccctgg gagctgaaca 8340 gggcagagaa atgggaagct cgggtacaga gggagtggga aagatgggtt tgggcttgca 8400 gtactgaacc caggaatgac agtaactgtg tgtgttgctg caggtgacaa aatatctgaa 8460 cagaagagga cttaggagag atctgaactc cagctgccct acaaactccg tcacagcttt 8520 tcttctcact tcatgtgaaa actaccccag tggctgactg aattgctgac ccttcaagct 8580 ctgtccttat ccattacctt aaagcagtca ttccttagta aagtttccaa caaatagaaa 8640 ttaatgaata aatgttgaca ctttgatagc actgatatgg agattatcct ttcattgagc 8700 cttttatcct ctggtcttct ttgaagaacc cctcactgtc accttcctga gaatactcta 8760 agaccaataa atacttcagt atttcagagc tgggagactc tgagtcattc ttactggaag 8820 tctaggacca ggtcacatgt gaatactatt tcttgaaggt gtggtttcaa cctctattgc 8880 agatgtagtt actaaaggtt ctgatcccac ctgaatggaa aggtctgagg atattgattc 8940 agccctgggt tcttccctaa ctacaggata gggtggggca gagaaaggat attgggggga 9000 aattttactt ggatgaagat tttcttggat gtagtttgaa gactgcagtg tttgaagtct 9060 ctgagggaag agatttggtc tgtctggatc aagatttcag gcagattagg attccattca 9120 cagcccctga gcttccttcc caaggctgga ttgtaattat agcaatattt catggaggat 9180 tttttctaca tgataaacta agagccaaga aataaaattt taaaaatgcc ctcattcatt 9240 gcaattttta ccagccatag tcactccatg tggaagaact taaatcatga ttaccagggc 9300 ttccaaaagt ttgagaatag tgatgattat gaagaaaaat atcttatttg agcaaggatt 9360 ttgtttcttt atgggtgttc attagatatt atgatgaaaa aagcacgaaa tggtaaaaat 9420 gcagataaat ataaaaacat gttttctagg tttcttttta tttttaagtt aaaaaaggaa 9480 ttgtttaaag tgaaaattat ttgggggttt ataacatacc cagaagtaaa atatgatgac 9540 aatggcacaa agaatagaag ggagaaatgg aagtgtaatg ttgtaagttt cttgtacatg 9600 tgaagtggtg tgttattatt tgaaggtaga atgtattaag atgaatattt taaactcctg 9660 ataactactg gaaaaa 9676 //