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EBI Dbfetch

ID   L76288; SV 1; linear; genomic DNA; STD; HUM; 6705 BP.
XX
AC   L76288;
XX
DT   19-JAN-2000 (Rel. 62, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 3)
XX
DE   Homo sapiens HLA-A gene, HLA-A-2301 allele exons 1-8.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-6705
RX   PUBMED; 9164942.
RA   Magor K.E., Taylor E.J., Shen S.Y., Martinez-Naves E., Valiante N.M.,
RA   Wells R.S., Gumperz J.E., Adams E.J., Little A.-M., Williams F.,
RA   Middleton D., Gao X., McCluskey J., Parham P., Lienert-Weidenbach K.;
RT   "Natural inactivation of a common HLA allele (A*2402) has occurred on at
RT   least three separate occasions";
RL   J. Immunol. 158(11):5242-5250(1997).
XX
DR   MD5; 3086256b0ee3300d656bfa40d09ec217.
DR   IMGT/HLA; A*23:01:01; HLA00048.
XX
CC   GSDB:S:74202
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..6705
FT                   /organism="Homo sapiens"
FT                   /mol_type="genomic DNA"
FT                   /haplotype="A23,24, B42,50"
FT                   /cell_line="SHJO"
FT                   /db_xref="taxon:9606"
FT   CAAT_signal     1114..1118
FT                   /gene="HLA-A"
FT                   /note="putative"
FT   TATA_signal     1140..1144
FT                   /gene="HLA-A"
FT                   /note="putative"
FT   exon            1192..1264
FT                   /gene="HLA-A"
FT                   /number=1
FT                   /note="putative"
FT   intron          1265..1394
FT                   /gene="HLA-A"
FT                   /number=1
FT                   /note="putative"
FT   exon            1395..1664
FT                   /gene="HLA-A"
FT                   /number=2
FT                   /note="putative"
FT   intron          1665..1905
FT                   /gene="HLA-A"
FT                   /number=2
FT                   /note="putative"
FT   exon            1906..2181
FT                   /gene="HLA-A"
FT                   /number=3
FT                   /note="putative"
FT   intron          2182..2760
FT                   /gene="HLA-A"
FT                   /number=3
FT                   /note="putative"
FT   exon            2761..3036
FT                   /gene="HLA-A"
FT                   /number=4
FT                   /note="putative"
FT   intron          3037..3138
FT                   /gene="HLA-A"
FT                   /number=4
FT                   /note="putative"
FT   exon            3139..3255
FT                   /gene="HLA-A"
FT                   /number=5
FT                   /note="putative"
FT   intron          3256..3697
FT                   /gene="HLA-A"
FT                   /number=5
FT                   /note="putative"
FT   exon            3698..3730
FT                   /gene="HLA-A"
FT                   /number=6
FT                   /note="putative"
FT   intron          3731..3872
FT                   /gene="HLA-A"
FT                   /number=6
FT                   /note="putative"
FT   exon            3873..3920
FT                   /gene="HLA-A"
FT                   /number=7
FT                   /note="putative"
FT   intron          3921..4088
FT                   /gene="HLA-A"
FT                   /number=7
FT                   /note="putative"
FT   exon            4089..4093
FT                   /gene="HLA-A"
FT                   /number=8
FT                   /note="putative"
XX
SQ   Sequence 6705 BP; 1566 A; 1675 C; 1817 G; 1647 T; 0 other;
     cttaggttta aatacattgt tttatggatt ttaatacatc catctacaga gcctagcagg        60
     gtgtccttgg cagttgtctt ttaatacctc atgtgggtct gcctaaaaac taatttttta       120
     tgttaatcag gtttaaaaat tactaagtgt tcctataaaa tatacacaac acttagaagt       180
     ggatacttcc taaaaacaga cagtgcatga gcactagtga ggggcattgt gagtgcattg       240
     aacagttgca actttgaggt gaataaagcc tgtaatggct tctggttgca acatatagga       300
     acacagtcgc tactttgtat tgaggagatg tcctggactc acacagaaac tcagagctat       360
     ggaatgatgg taaatttaaa atactacaag caggagtcac agatacattg tctgggaaaa       420
     tgcaacttag tagctttgtg agtcctgttg taaggctttt ggacacattt atacatcaag       480
     gggccaaagt cacatttttt acctattaga ttcctgatca ttcaggggtt accaagattc       540
     tgctacccac tgtagttaat aaacaaagag caaattggtc tctattctgt ctcatgcact       600
     caggcgcaac tcttcctgat taaaaacaaa aacaacaaca acaaaaatct acacctccat       660
     tcccagagca agcttactct ctggcaccaa actccatggg atgatttttc ttctagaaga       720
     gtccaggtgg acaggtaagg agtgggagtc agggagtcca gttcagggac agagattacg       780
     ggatgaaaag tgaaaggaga gggacggggc ccatgccgag ggtttctccc ttgtttctca       840
     gacagctctt gggccaagat tcagggagac attgagacag agcgcttggc acagaagcag       900
     aggggtcagg gcgaagtccc agggccccag gcgtggctct cagggtctca ggccccgaag       960
     gcggtgtatg gattggggag tcccagcctt ggggattccc caactccgca gtttcttttc      1020
     tccctctccc aacctatgta gggtccttct tcctggatac tcacgacgcg gacccagttc      1080
     tcactcccat tgggtgtcgg gtttccagag aagccaatca gtgtcgtcgc ggtcgctgtt      1140
     ctaaagtccg cacgcaccca ccgggactca gattctcccc agacgccgag gatggccgtc      1200
     atggcgcccc gaaccctcgt cctgctactc tcgggggccc tggccctgac ccagacctgg      1260
     gcaggtgagt gcggggtcgg gagggaaacg gcctctgcgg ggagaagcaa ggggcccgcc      1320
     tggcgggggc gcaagacccg ggaagccgcg ccgggaggag ggtcgggcgg gtctcagcca      1380
     ctcctcgtcc ccaggctccc actccatgag gtatttctcc acatccgtgt cccggcccgg      1440
     ccgcggggag ccccgcttca tcgccgtggg ctacgtggac gacacgcagt tcgtgcggtt      1500
     cgacagcgac gccgcgagcc agaggatgga gccgcgggcg ccgtggatag agcaggaggg      1560
     gccggagtat tgggacgagg agacagggaa agtgaaggcc cactcacaga ctgaccgaga      1620
     gaacctgcgg atcgcgctcc gctactacaa ccagagcgag gccggtgagt gaccccggcc      1680
     cggggcgcag gtcacgaccc ctcatccccc acggacgggc cgggtcgccc acagtctccg      1740
     ggtccgagat ccaccccgaa gccgcgggac cccgagaccc ttgccccggg agaggcccag      1800
     gcgccttaac ccggtttcat tttcagttta ggccaaaaat ccccccgggt tggtcggggc      1860
     cgggcggggc tcgggggact gggctgaccg cggggtcggg gccaggttct cacaccctcc      1920
     agatgatgtt tggctgcgac gtggggtcgg acgggcgctt cctccgcggg taccaccagt      1980
     acgcctacga cggcaaggat tacatcgccc tgaaagagga cctgcgctct tggaccgcgg      2040
     cggacatggc ggctcagatc acccagcgca agtgggaggc ggcccgtgtg gcggagcagt      2100
     tgagagccta cctggagggc acgtgcgtgg acgggctccg cagatacctg gagaacggga      2160
     aggagacgct gcagcgcacg ggtaccaggg gccacggggc gcctacctga tcgcctgtag      2220
     gtctcccggg ctggcctccc acaaggaggg gagacaattg ggaccaacac tagaatatcg      2280
     ccctccctct ggtcctgagg gagaggaatc ctcctgggtt tccagatcct gtaccagaga      2340
     gtgactctga ggttccgccc tgctctctga cacaattaag ggataaaatc tctgacggaa      2400
     tgacggaaag acgatccctc gaatactgat gactggttcc ctttgacacc ggcagcagcc      2460
     ttgggaccgt gacttttcct ctcaggcctt gttctctgct tcacactcaa tgtgtgtggg      2520
     ggtctgagtc cagcacttct gagtccctca gcctccactc aggtcaggac cagaagtcgc      2580
     tgttccctcc tcagggaata gaagattatc ccaggtgcct gtgtccaggc tggtgtctgg      2640
     gttctgtgct ctcttcccca tcccgggtgt cctgtccatt ctcaagatgg ccacatgcat      2700
     gctggtggag tgtcccatga cagatgcaaa atgcctgaat tttctgactc ttcccgtcag      2760
     acccccccaa gacacatatg acccaccacc ccatctctga ccatgaggcc actctgagat      2820
     gctgggccct gggcttctac cctgcggaga tcacactgac ctggcagcgg gatggggagg      2880
     accagaccca ggacacggag cttgtggaga ccaggcctgc aggggatgga accttccaga      2940
     agtgggcagc tgtggtggta ccttctggag aggagcagag atacacctgc catgtgcagc      3000
     atgagggtct gcccaagccc ctcaccctga gatggggtaa ggagggagat gggggtgtca      3060
     tgtctcttag ggaaagcagg agcctctctg gagaccttta gcagggtcag ggcccctcac      3120
     cttcccctct tttcccagag ccatcttccc agcccaccgt ccacatcgtg ggcatcattg      3180
     ctggcctggt tctccttgga gctgtgatca ctggagctgt ggtcgctgct gtgatgtgga      3240
     ggaggaacag ctcaggtgga gaaggggtga agggtggggt ctgagatttc ttgtctcact      3300
     gagggttcca agccccagct agaaatgtgc cctgtctcat tactgggaag caccatccac      3360
     aatcatgggc cgacccagcc tgggccctgt gtgccagcac ttactctttt gtaaagcacc      3420
     tgtgacaatg aaggacagat ttatcacctt gattatggcg gtgatgggac ctgatcccag      3480
     cagtcacaag tcacagggga aggtccctga cgacagatct caggagggcg attggtccag      3540
     ggcccacatc tgctttcttc atgtttcctg atcctgccct gggtctgcag tcacacattt      3600
     ctggaaactt ctctggggtc caagactagg aggttcctct aggaccttaa ggccctggct      3660
     cctttctggt atctcacagg acattttctt cccacagata gaaaaggagg gagctactct      3720
     caggctgcaa gtaagtatga aggaggctga tgcctgaggt ccttgggata ttgtgtttgg      3780
     gagcccatgg gggagctcaa ccaccccaca attcctcctc tagccacatc ttctgtggga      3840
     tctgaccagg ttctgttttt gttctacccc aggcagtgac agtgcccagg gctctgatgt      3900
     gtctctcaca gcttgtaaag gtgagagctt ggagggcctg atgtgtgttg ggtgttgggc      3960
     ggaacagtgg acacagctgt gctatggggt ttctttgcat tggatgtatt gagcatgcga      4020
     tgggctgttt aaagtgtgac ccctcactgt gacagatatg aagttgttca tgaatttttt      4080
     ttctatagtg tgagacagct gccttgtgtg ggactgagag gcaagagttg ttcctgccct      4140
     tccctttgtg acttgaagaa ccctgacttt gtttctgcaa aggcacctgc atgtgtctgt      4200
     gttcatgtag gcataatgtg aggaggtggg gagaccaccc cacccccatg tccaccatga      4260
     ccctcttccc acgctgacct gtgctccctc cccaatcatc tttcctgttg cagagaggtg      4320
     gggctgaggt gtctccatct ctgtctcaac ttcatggtgc actgagctgt aacttcttcc      4380
     ttccctatta aaattagaac ctgagtataa atttactttc tcaaattctt gccatgagag      4440
     gttgatgagt taattaaagg agaagattcc taaaatttga gagacaaaat aaatggaaca      4500
     catgagaacc ttccagagtc cacgtgttgc ttatgctgat ttgttgcagg ggaggagact      4560
     agatggggct gtgcccagtt tctgttccgg ccaccatggg ctttatgtgg tcactgcttg      4620
     gctgggtcat ctttgctgct ccattgtcct tggcccttca gtagaacctt gtcccaccaa      4680
     gacccgtgat tacagggagt tggatgtcac ctagggtggt ccctgcatac aaatctcctt      4740
     gtggtagcaa gagacaaatt ttcagacctg tccaggtctt gccttcctcc cagggctttt      4800
     tcctcaattg tattttcgat ttttctccaa tctttttaaa ggaaccagat tgtgacattt      4860
     gcagagagga ggggtcccat agtttctcat catgattaac tttctgttgg aactcctctt      4920
     ctgctctcct actcttcttc ctgctctaag ttgtagtaat cctagtgctg gctccaatcc      4980
     aaactcatag atttataaag cagagtctaa tttagattca tatgtggttg gaaaattgta      5040
     cccataaggc tagggttatt gttcctgaag agaaatatat ggttttgtgc tgaagtgtgc      5100
     aggagggttg gtgtgggagg agggaggaca cacaagcagc cctggtgaga aaagcactgg      5160
     cggcatggat gtccatgtga acttatgttc tttagctgcc acaaaacagc atttgccctg      5220
     tggctacatt aataaaggta tgggctttag aatagggagg tgctctacag tgatcattca      5280
     ttcaactgac atttgttgtc tgctagggat atgactgctt ttgcatttag aaagcatcat      5340
     taaagtaaaa acagaaaaat ttctggggtt atggtgcata cgttctagat gcaggcttgt      5400
     ccaatccgcg gcttgtgggc tgcatgtggc ccaggacaat tttgaatgtg aggacttttt      5460
     tgcttatctg tggtgaacct gagtcctgga gtgagtgcac ccacctccct cagggtcagg      5520
     agtgaatgct ttaggaaccc tccttttcag tgacctgcca aagataaagg gcacatttac      5580
     tgtgataacc cagagtatca gccaaggggg cttgaccttc aaggagttat gggaaagctt      5640
     aataaagggt ggtgtcccag ggtcagaaaa gatgggcaga cagcaagagc actgcttgat      5700
     atctatgata agcatgtaag aattgaggag caagcttcag attcagaatc cagtgactaa      5760
     ggacatatct atatccctaa gagaaagaac cttgggacac gatgatggtt acatgctggg      5820
     acaattccat cagcccttct gcaaaggagc ctatagccat ttaatcagga gatgggataa      5880
     gtattaacat tgggtgtgag ctgacattgc tgcccagatt cccacagcac cattatgtcc      5940
     cccatcacac tggggcttac agaggctggg gaataaacct agacacatta tgccccatgg      6000
     tggaatcacc ggttccataa atcctgtcct gattatctcc ccattctctt agcgcataat      6060
     tggccttgat gcactggcaa ctggagtcac cccacactgt gtccctagtc tggagagtaa      6120
     gggatctcat tgtgctgaag cccaaaggga aacatccctc atccaagcca aaccagaagc      6180
     aatattgtgc cccagggtgg gtcttgtgga ggttactgca ggtattatag gggtggcact      6240
     gccattacag acctgaacga tgcgaggtgg tgttgggatt gcctgttatc tccatataat      6300
     tcagcaatct gtacctgcag aagcctgata cggctaaaga atgaatggaa ttactccaga      6360
     cttgaccaag taggagtcct gattgcagct gccatgctgg ctggatatca ctgcctgggg      6420
     agattaataa ggcctcaggc acatggcaag cagctgtgga tttggtgagt gcattccctc      6480
     ccatttcatt tagaagatgg atatggaatg attcacattc acatgggatt tataatacat      6540
     ttattgatag cttgcctcag ggctacctta actcctcaac cttctataaa tatcacctta      6600
     agagacctgg acaaatcaga catctcacag aatactaaat ctcttcattt cactggcaat      6660
     atcacataaa ttgggaagga tgaacaagag caggaaagta tgctg                      6705
//


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