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EBI Dbfetch

ID   L29409; SV 1; linear; genomic DNA; STD; HUM; 1173 BP.
XX
AC   L29409;
XX
DT   14-OCT-1994 (Rel. 41, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 6)
XX
DE   Homo sapiens MHC class I gene fragment (HLA A1, C7, B8, BfS, C4AQ0, C4B1,
DE   DR3, DQ2).
XX
KW   cell surface antigen; cell surface glycoprotein; class I gene;
KW   integral membrane protein; major histocompatibility complex.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-1173
RX   DOI; 10.1007/BF01246675.
RX   PUBMED; 7927538.
RA   Leelayuwat C., Townend D.C., Degli-Esposti M.A., Abraham L.J.,
RA   Dawkins R.L.;
RT   "A new polymorphic and multicopy MHC gene family related to nonmammalian
RT   class I";
RL   Immunogenetics 40(5):339-351(1994).
XX
DR   MD5; c11ee7dfa940d82135ceeba0b7ea2c6e.
DR   Ensembl-Gn; ENSG00000183214; homo_sapiens.
DR   Ensembl-Gn; ENSG00000235233; homo_sapiens.
DR   Ensembl-Tr; ENST00000400325; homo_sapiens.
DR   Ensembl-Tr; ENST00000418465; homo_sapiens.
DR   Ensembl-Tr; ENST00000547609; homo_sapiens.
DR   GOA; Q29983.
DR   HGNC; HGNC:7090; MICA.
DR   IMGT/HLA; MICA*008:01:01; HLA01019.
DR   InterPro; IPR001039; MHC_I_a_a1/a2.
DR   InterPro; IPR003597; Ig_C1-set.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR011161; MHC_I-like_Ag-recog.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PDB; 1B3J; X-ray.
DR   PDB; 1HYR; X-ray.
DR   UniProtKB/Swiss-Prot; Q29983; MICA_HUMAN.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1173
FT                   /organism="Homo sapiens"
FT                   /map="6p21.3"
FT                   /isolate="8.1 AH (R6-12373)"
FT                   /mol_type="genomic DNA"
FT                   /haplotype="HLA A1, C7, B8, BfS, C4AQ0, C4B1, DR3, DQ2"
FT                   /cell_type="B-lymphocyte"
FT                   /note="60kb centromeric of HLA B"
FT                   /db_xref="taxon:9606"
FT   misc_feature    1..1173
XX
SQ   Sequence 1173 BP; 266 A; 312 C; 332 G; 258 T; 5 other;
     ctctcccctt ggcccctatt cccttagggg gcttgtggsc acccagtcct tgcacctggs        60
     ctacaagttt gccatcttca ttcccccttc ttctgttcat cagccccctc ctctatcctc       120
     ccaccctcac agttttcttt gtatatgaaa tcctcgttct tgtccctttg cccgtgtgca       180
     tttcctgccc caggaaggtt gggacagcag acctgtgtgt taaacatcaa tgtgaagtta       240
     cttccaggaa gaagtttcac ctgtgatttc ctcttcccca gagccccaca gtcttcgtta       300
     taacctcacg gtgctgtcct gggatggatc tgtgcagtca gggtttcttg ctgaggtaca       360
     tctggatggt cagcccttcc tgcgctatga caggcagaaa tgcagggcaa agccccaggg       420
     acagtgggca gaagatgtcc tgggaaataa gacatgggac agagagacca gggacttgac       480
     agggnaacgg aaaggacctc aggatgaccc tggctcatat caaggaccag aaagaaggtg       540
     agagtcggca ggggcaagag tgactggaga ggccttttcc agaaaagtta ggggcagaga       600
     gcagggacct gtctcttccc actggatctg gctcaggctg ggggtgagga atgggggtca       660
     gtggaactca gcagggaggt gagccggcac tcagcccaca cagggaggca tggaggaggs       720
     ccagggaggc ataccccctg ggctgagttc ctcacttggg tggaaaggtg atgggttcgg       780
     gaatggagaa gtcactgctg ggtgggggca ggcttgcatt ccctccagga gattagggtc       840
     tgtgagatcc atgaagacaa cagcaccagg agctcccagc atttctacta cgatggggag       900
     ctcttcctct cccaaaacct ggagactgag gaatggacag tgccccagtc ctccagagct       960
     cagaccttgg mcatgaacgt caggaatttc ttgaaggaag atgccatgaa gaccaagaca      1020
     cactatcacg ctatgcatgc agactgcctg caggaactac ggcgatatct agaatccggc      1080
     gtagtcctga ggagaacagg taccgacgct ggccaggggc tctcctctcc ctccaattct      1140
     gctagagttg cctcacctcc cagatgtgtc cag                                   1173
//


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