Dbfetch
ID K01923; SV 1; linear; mRNA; STD; MUS; 978 BP. XX AC K01923; XX DT 13-JUN-1985 (Rel. 06, Created) DT 09-SEP-2004 (Rel. 81, Last updated, Version 6) XX DE Mouse MHC class II H2-IA-alpha gene (d haplotype) mRNA, complete cds. XX KW antigen; cell surface glycoprotein; class II gene; glycoprotein; KW histocompatibility antigen; integral membrane protein; KW major histocompatibility complex. XX OS Mus musculus (house mouse) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. XX RN [1] RP 1-978 RX DOI; 10.1016/0092-8674(83)90147-2. RX PUBMED; 6309407. RA Benoist C.O., Mathis D.J., Kanter M.R., Williams V.E.II., McDevitt H.O.; RT "Regions of allelic hypervariability in the murine A alpha immune response RT gene"; RL Cell 34(1):169-177(1983). XX DR MD5; 0c313d85bd11a7f33537926ae71e157d. XX CC The protein domains are as follows: first external protein domain CC (D1) at bases 93-356; second external protein domain (D2) at bases CC 357-638; connecting peptide, transmembrane region, and cytoplasmic CC tail (CP,TM,C) at bases 639-791. [1] also sequenced the IA-alpha CC genes from mice of b,f,u and q haplotypes. XX FH Key Location/Qualifiers FH FT source 1..978 FT /organism="Mus musculus" FT /sub_species="domesticus" FT /strain="BALB/c" FT /mol_type="mRNA" FT /haplotype="d" FT /tissue_type="spleen" FT /db_xref="taxon:10090" FT mRNA <1..>978 FT /note="IA-alpha mRNA" FT sig_peptide 24..92 FT /gene="MHC H2-IA-alpha" FT CDS 24..794 FT /codon_start=1 FT /gene="MHC H2-IA-alpha" FT /db_xref="GOA:P04228" FT /db_xref="InterPro:IPR001003" FT /db_xref="InterPro:IPR003006" FT /db_xref="InterPro:IPR003597" FT /db_xref="InterPro:IPR007110" FT /db_xref="InterPro:IPR011162" FT /db_xref="InterPro:IPR013783" FT /db_xref="InterPro:IPR014745" FT /db_xref="InterPro:IPR036179" FT /db_xref="MGI:MGI:95895" FT /db_xref="PDB:1ES0" FT /db_xref="PDB:1F3J" FT /db_xref="PDB:1IAO" FT /db_xref="PDB:2IAD" FT /db_xref="PDB:3CUP" FT /db_xref="PDB:3MBE" FT /db_xref="PDB:5DMK" FT /db_xref="PDB:6BLQ" FT /db_xref="PDB:6BLR" FT /db_xref="PDB:6BLX" FT /db_xref="PDB:6DFS" FT /db_xref="PDB:6DFW" FT /db_xref="UniProtKB/Swiss-Prot:P04228" FT /protein_id="AAA39615.1" FT /translation="MPCSRALILGVLALNTMLSLCGGEDDIEADHVGFYGTTVYQSPGD FT IGQYTHEFDGDELFYVDLDKKKTVWRLPEFGQLILFEPQGGLQNIAAEKHNLGILTKRS FT NFTPATNEAPQATVFPKSPVLLGQPNTLICFVDNIFPPVINITWLRNSKSVTDGVYETS FT FLVNRDHSFHKLSYLTFIPSDDDIYDCKVEHWGLEEPVLKHWEPEIPAPMSELTETVVC FT ALGLSVGLVGIVVGTIFIIQGLRSGGTSRHPGPL" FT mat_peptide 93..791 FT /gene="MHC H2-IA-alpha" XX SQ Sequence 978 BP; 220 A; 263 C; 245 G; 250 T; 0 other; gcagagacct cccagagacc aggatgccgt gcagcagagc tctgattctg ggggtcctcg 60 ccctgaacac catgctcagc ctctgcggag gtgaagacga cattgaggcc gaccacgtag 120 gcttctatgg tacaactgtt tatcagtctc ctggagacat tggccagtac acacatgaat 180 ttgatggtga tgagttgttc tatgtggact tggataagaa gaaaactgtc tggaggcttc 240 ctgagtttgg ccaattgata ctctttgagc cccaaggtgg actgcaaaac atagctgcag 300 aaaaacacaa cttgggaatc ttgactaaga ggtcaaattt caccccagct accaatgagg 360 ctcctcaagc gactgtgttc cccaagtccc ctgtgctgct gggtcagccc aacaccctta 420 tctgctttgt ggacaacatc ttcccacctg tgatcaacat cacatggctc agaaatagca 480 agtcagtcac agacggcgtt tatgagacca gcttcctcgt caaccgtgac cattccttcc 540 acaagctgtc ttatctcacc ttcatccctt ctgatgatga catttatgac tgcaaggtgg 600 agcactgggg cctggaggag ccggttctga aacactggga acctgagatt ccagccccca 660 tgtcagagct gacagaaact gtggtgtgtg ccctggggtt gtctgtgggc cttgtgggca 720 tcgtggtggg caccatcttc atcattcaag gcctgcgatc aggtggcacc tccagacacc 780 cagggccttt atgagtcaca ccctggaaag gaaggtgtgt gtccctcttc atggaagaag 840 tggtgtgctg ggtgacctgg cacagtgtgt tttctggacc aatttatggt gttctttttc 900 ttcttcaagt gacccccaac ttgcttttcc cttggccctg aggctgtccc tctcacagct 960 cacacaccct tggaattc 978 //