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EBI Dbfetch

ID   JN157603; SV 1; linear; genomic DNA; STD; HUM; 11056 BP.
XX
AC   JN157603;
XX
DT   18-DEC-2011 (Rel. 111, Created)
DT   18-DEC-2011 (Rel. 111, Last updated, Version 1)
XX
DE   Homo sapiens MHC class II antigen (HLA-DRB1) gene,
DE   HLA-DRB1-DRB1*15:01:01:01v allele, complete cds.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-11056
RA   Xu Y., Deng Z., Yang B.;
RT   "Characterization and polymorphism analyses of HLA-DRB1 genomic full length
RT   in Chinese Han population";
RL   Unpublished.
XX
RN   [2]
RP   1-11056
RA   Xu Y., Deng Z., Yang B.;
RT   ;
RL   Submitted (18-JUN-2011) to the INSDC.
RL   Immunogenetic Laboratory, Shenzhen Blood Center, 2# Meigang South Street,
RL   Nigang West Road, Shenzhen, Guangdong 518035, China
XX
DR   MD5; 3bb2753595aaf099a490a7ce1e042fce.
DR   Ensembl-Gn; ENSG00000196126; homo_sapiens.
DR   Ensembl-Tr; ENST00000360004; homo_sapiens.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..11056
FT                   /organism="Homo sapiens"
FT                   /mol_type="genomic DNA"
FT                   /PCR_primers="fwd_seq: ggaccttcatacagcatctctg, rev_seq:
FT                   ggtttaggcaaaggggagcac"
FT                   /db_xref="taxon:9606"
FT   gene            <189..11056
FT                   /gene="HLA-DRB1"
FT                   /allele="DRB1*15:01:01:01v"
FT   mRNA            join(<189..288,5553..5822,8089..8370,9071..9181,9657..9680,
FT                   10823..11056)
FT                   /gene="HLA-DRB1"
FT                   /allele="DRB1*15:01:01:01v"
FT                   /product="MHC class II antigen"
FT   CDS             join(189..288,5553..5822,8089..8370,9071..9181,9657..9680,
FT                   10823..10836)
FT                   /codon_start=1
FT                   /gene="HLA-DRB1"
FT                   /allele="DRB1*15:01:01:01v"
FT                   /product="MHC class II antigen"
FT                   /db_xref="GOA:D7RIH8"
FT                   /db_xref="IMGT/HLA:DRB1*15:01:01:04"
FT                   /db_xref="InterPro:IPR000353"
FT                   /db_xref="InterPro:IPR003006"
FT                   /db_xref="InterPro:IPR003597"
FT                   /db_xref="InterPro:IPR007110"
FT                   /db_xref="InterPro:IPR011162"
FT                   /db_xref="InterPro:IPR013783"
FT                   /db_xref="InterPro:IPR014745"
FT                   /db_xref="UniProtKB/TrEMBL:D7RIH8"
FT                   /protein_id="AEV76920.1"
FT                   /translation="MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECH
FT                   FFNGTERVRFLDRYFYNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAV
FT                   DTYCRHNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLN
FT                   GQEEKAGMVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSE
FT                   SAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS"
FT   3'UTR           10837..11056
FT                   /gene="HLA-DRB1"
FT                   /allele="DRB1*15:01:01:01v"
XX
SQ   Sequence 11056 BP; 2887 A; 2233 C; 2676 G; 3260 T; 0 other;
     accagcaact gatgatgcta ttgaactcag atgctgattg gttctccaac acgagattac        60
     ccaacccagg agcaaggaaa tcagtaactt cctccctata acttggaatg tgggtggagg       120
     ggttcatagt tctccctgag tgagacttgc ctgcttctct ggcccctggt cctgtcctgt       180
     tctccagcat ggtgtgtctg aagctccctg gaggctcctg catgacagcg ctgacagtga       240
     cactgatggt gctgagctcc ccactggctt tgtctgggga cacccgacgt aagtgcacat       300
     tgcgggtgct gagctactat ggggtgggga aaatagggag ttttgttaac attgtgccca       360
     ggccatgtcc cttaagaaat tgtgacgttt tcttcagaga ttgcccatct ttatcattgg       420
     atcccaaatt atttcctcca taaaaggagc ttgggtactt gccctcttca tgagacttgt       480
     gtaaggggcc tttgcacaaa tcatttcttt tcaaatctcc accaataaaa cctttgcatc       540
     acatgtcctc agggtcttta gaggatttag aaataaggat tctaaaataa attccccata       600
     cagcacttcc ctttattatg ttgacttatg tcagacaaaa ggaggttctt actgaaaatt       660
     ttgtgggagt caagggaatt caaagggtct ctcctagacg atccagtgtt aggttcccca       720
     caggaccttt ggtgttggcc atagtcctca tatgtgagga tggacccagt ggcctcccca       780
     ttatctcctt tcttttcttg ctgaactcca atgtttataa ggcctgtatc cctgtagtgt       840
     atgtaggttc tctgacagaa gttatactta gtgctcttcc tttcttgtgg ggaaaagtcc       900
     ctggaactga agctgagatt gttaatactt ggagtcacct tacagataca gagcatttat       960
     gaggtattct ttggtgccta aagaacttaa ggcatcctct gaaaaactag cccaggttcg      1020
     tgttcattat gaatcttttt taacctttct gtacttgttt ctcttgcatc tcctatgtgc      1080
     tctaactaga catgacagaa gagatttaac taatgtataa attatacgaa attctatttt      1140
     ttaagtcaaa aataatcaac tatcagaaat ttaataatgt tcaaactata tactctgtgt      1200
     ggggttaccg agatgatgtg aacattgttc acgtctcata gggctgaaag tcaatgggca      1260
     agtcttggga actcattgtc ttactggggt cttgtcctaa atttcctagg ttcacccatc      1320
     atgccctcag ctttccttaa ctagccatgt ctgcttacct cttcctccag tttctatttt      1380
     tccccagcta tgttgtcatc atttccagaa atctctaaag cttgcacaga accttagcac      1440
     tatgagattc attgaaagag actttttttc tctttttgag gtagggcctg gctctgtcac      1500
     ccagtctata gctcagtggt gtgatcgagg ctcactgcaa cctctgccac ttatgctcaa      1560
     gtgatcctcc ctcctcaggc tccagagtag ctgggaatac aggcaggcaa ccacgcccag      1620
     ctaatttttg taattttggt agacatgaga ttttgccatg ttgcccaggc tggtcttgaa      1680
     ctgctggact caagcaatcc tcctgccttg gcctcccaac atgctaggat tatagatgtg      1740
     agacactgtg cccaggcaaa agagatgact cttaataaaa aaatttcctt tttcttaaat      1800
     cactgtttct ttatctgtga attcttcttc caactagaag gaggagaaaa aagaagtttg      1860
     cctgtattta tcactgggag gagaaggggt ctagtgtgac attaaaatga aagagtgctg      1920
     gagcttgagc cccttcttgc tttccaggat ccctacagtg atcagttccc ataccctggt      1980
     ttattcatgt aaaccacact tatttttctc agcagctact ctttactggg ctccattcta      2040
     ggttcaaatc attctatttg attaagttag agagcgtccc tactctcatg gaagttacac      2100
     aagagtagag gagacagaca ctaacccaat aagcatttaa caaagaagat aatgttagag      2160
     agtcatagtg cactgaagaa aagacatcag gtttgtgaaa aagagagaca tggattcacc      2220
     tactttagtt catatgttag ggagctccac ctgagaaagt gacattcagc tgagacaaca      2280
     aaataagtag acagtcgtga agatctaagg gatgaaagtt ccagggagac cgaatcgggg      2340
     gaaagccctg atgtgttaaa ttatgtggag ggagagaaag aaagctagag gggctgatgt      2400
     atagaaagca aggaaatgga gaggcagaag atgagggtag gacacagaga ggaattcagg      2460
     agcctcatca ttataggctc tgatgtccac agtaaaaaaa aattaaattt tattatttat      2520
     ttatttgttt gtttatttta ttttattttg tgatggagtc tctctctgtt gcccaggcta      2580
     gattgctgtg gcacaatctc ggctcactgc aacctccgcc tcctgggttc aagcgattct      2640
     cctgcctcag cctcccgatt agctggggcc acaggcgcat gccaccacac ctggctaatt      2700
     ttttgtattt ttagtaggga tagggtttca ccgtgttagc caggatggtc tcgatctcct      2760
     gacctcgtga tccgcccgcc ttggcctccc aaagtgctgg gattacaggc gtgagccact      2820
     gcgcccggcc tatattcaat gtttaaaact aattctagct actctgtggg gattggattg      2880
     ttggggttca ctagtggtta ggaagactat ttaggagcac agcagggaat tcttcaggga      2940
     aaacaggttt gtggcttcat ggagtgcatt agtgataaag atggtgaaaa agataaagtg      3000
     gacagacttg gcatgtattt ttgcttagct tgttaatgaa ttactgtaaa gggggtagaa      3060
     caatcaagct tattcctaag gattttcttt tgacaaataa atgggtggta gtgttgttta      3120
     ttgagatagg aaaaactatg ggaggaaatg atttgaagtg ggtggtttga aataaaagtt      3180
     ttgtttaaat atgagatgat tgattgacat ttatgtggag aaatccgaag gtcaatggca      3240
     tttaagagac tcatggtgag gccagggctt caggtattta tgttggcagc agcaatacgt      3300
     gtagtgtgtt aaattccagg gcgtggaaga ggatacatag ggagatggat tgtgtgaaga      3360
     aaaaagaaca gggcacaggc cagcaaaggg ggctgagaaa gagcccaagg atgctggaga      3420
     aaaaccaaga gaacatcatg tgtgtaagtc caggaaaata gattattttc aaggagaagg      3480
     gagaggccaa ttgtggtgag taccactaag aggaggggca agtgagaata tgatagagaa      3540
     gcaagtgctg ggtttggtgg agtcgatatt tgcagtcaat ggagcatcca ggtaggaaac      3600
     tggattggac catttgaaga gtgagtaaaa gtgaggacga ggttaaggtt gactgttttg      3660
     agtagagagc ttcagggaag gattgttctc tgggttcagg gagccagctg aacctaaagg      3720
     aaaaggctaa agaagctgaa gagaaggagg aggacctgtg aaccagagat gctcagtcat      3780
     tattagcgag gaaatacgga gagcccctgt gtgcagtggt gactactcat gcaaaatgtc      3840
     acacagccaa tatttaacac agccagtatt tcacacagcc aatatttatt agtgacatag      3900
     catataccag ttattactct aggtcatgag aatggagtga taaataaaat gaatccagtc      3960
     gccatcacta tatgccatgt aacattttgc aatgactgtg tatcaggcct atgaatttca      4020
     gtattcaatt tcaataatga tcctgttgta tctgtggtat ttaaaaacat atacatctct      4080
     ggaatctaaa attgagaggt tataagtaac acccagtatt acaaatttag tgctggaaat      4140
     cagattgcag tttaaatctg agcatataga aagtccgttt cttctatgtc agcagatgct      4200
     ttttgtgtga ggtttaggta tactgcatta tttgacataa accagtgttt ctgccctatg      4260
     tcttcagaat gacaattctt tatgaaacta atagaagaac agaagacaat tgcaaaatca      4320
     tgatgaagat actaattgct ttagaattaa ggaatacaaa aaataatatg agctgcagtt      4380
     ataggatcag aaaagttaaa atgggaatgt attcgagtgt ttattatgtg atcagtgcta      4440
     agaagtgtca tcatttaatt ttacacttaa cggtaatcct gtgaggatta cgctattatt      4500
     aaatgcattt gatagattac aaaaaggctt atggttggta aaaattgacc caagtagaag      4560
     agatcgtgtt tttattcagg ttttctgatt atagagtttg agagtttgac catcattagt      4620
     gagtagtgac tatattgtgt ctgaattatt gacacaattt ctgatattca tatgtaccag      4680
     gctgtttctt agagtgggga cagaaatgca agggctgcta gttctgatgt ataggagaaa      4740
     ctttcattca ttttgcattt atcattttaa acgttgtata tgtctatctg ggcatgtgtt      4800
     caagaacaca aggaagtatt aaatcactcc ttcttctgag gtttgactag caagttgggc      4860
     tagagttaca aataaaatac aggttcctag tgaaatctga atttcagata cacaaccata      4920
     atttattgga aatccaaatt taactgggaa tcttctatta ttctctgctc tagaacgcca      4980
     cacttctgat atttctcatt gctgtctaag ctcttgtgtg tttggttttt ggccatcgct      5040
     ttcactgctc tttaagctcc cccagaggag tggagaggtc tgttttccct cgtttggatt      5100
     cctagaggca gcgcaggcct ggcacaaggt catcactaag gaagtgttca cagggtgaac      5160
     gcggtgggtg ctgttgaagg taccggtaaa gcgtgtggga tgagaggagc agagagtgtc      5220
     tttggggctc ccaggaggag gcggcgcggg ctgcggtgct gggcggatcc tcctccagct      5280
     cctgcttgga ggtctccaga acaggctgga ggcagggagg gggtcccaaa agcctgggga      5340
     tgagaagggg ttttcccgca tggtccccca ggcccccgtt cgcctcagga agacggagga      5400
     tgagctcctg ggctgcaggt ggtgggcgtt gcgggtgggg ccggttaagg ttccagcgcc      5460
     cgcaccccgc tcagggagcc ccggatggtg gcgtcgctgt ccgtgtcttc tcaggaggcc      5520
     gccctgtgac cggatggttc gtgtccccac agcacgtttc ctgtggcagc ctaagaggga      5580
     gtgtcatttc ttcaatggga cggagcgggt gcggttcctg gacagatact tctataacca      5640
     ggaggagtcc gtgcgcttcg acagcgacgt gggggagttc cgggcggtga cggagctggg      5700
     gcggcctgac gctgagtact ggaacagcca gaaggacatc ctggagcagg cgcgggccgc      5760
     ggtggacacc tactgcagac acaactacgg ggttgtggag agcttcacag tgcagcggcg      5820
     aggtgagcat ggccgcgggc ggggcctgag tccccgtgag ctgggaatct gagtgtgtgt      5880
     gtgtgtgtgt gtgtgtgtgt gtgtgtgtga gagagagaca gagagagaca gagagaggaa      5940
     gagagagaga gagcgccatc tgtgagcatt tagaatcctc tcagtccgga gcaagcagtt      6000
     ctgagagcac aggtgtgtgt gtaaagtgtg gatttgtctg tgtctgtgtg tctgttgtgg      6060
     gaggggaggc aggagggggc tgtttcttat ccttggagac ctctgtgggg aggtgacaag      6120
     ggaggtgggt gctgggggct ggagagagag gagaccttga ttatctcggt ccttagagat      6180
     gcagggaagg gaaatgtaag gtgtgtgtgg ttggggtgaa ggtttagggg aggactgctg      6240
     aggggtaagg caggtttggg ataatgtgag gaggccagtt ccagactctc cctggcatac      6300
     acccttcgtg taatctctga attaaaagtg tgtgctgttt gtttgtaaaa gcaatagatt      6360
     aatttctaga ggaactgagt agacctctga ggcacctctg aagcttcttt agatctaaat      6420
     ttcttcctag ttttttgttt ttttcagtgt gtatattttt acatagtaga aatgactgtg      6480
     aaactaactt tttgaattaa agttttgaca cggttactat tttattataa tgctggtagt      6540
     tttctagtag ttacatatta ttcttttata tataatattt gtgacacaac tcacctcact      6600
     ttcccgtttg ttgaccttta ttatgacatt caccagaagt tgaaattgtg tgtttctggt      6660
     taatttttaa tttatatttt ttatttgtaa ttcctttgaa ttattttgcc ctatttattg      6720
     gccgattata attattgctc taagaattcc ctattgtatt tggtaggtaa tggacaatga      6780
     tctacggtct aatatcttga gggcttagta tttttctcag tgactttctg cgttctttgt      6840
     actataagat tattaacact ttattgatat ttgatccagc atttgctcca gtttgtggtt      6900
     tgtatgtgga ttttgaaaat tcttttccat gttaagaatt tgaacatttt tatttaataa      6960
     aatatattgc aacattttta ttaatgatct acaatccatc tgaaatctgc cattttgtgg      7020
     cattgttgtc tccaggtttc tccttacttc taaaaaaata gttgtattta ttgagagtat      7080
     gctagtgtcg gggattttcc tgggcataag caccccaagt aacgagtccc agacactgcc      7140
     ttaatccaaa tgtgattctg gaaagaaaaa tcattttaca atgataggcc taataataat      7200
     tatgcttgtg ttgcacggga gatgcattga tcagctaaat gtaaatataa gaactttcaa      7260
     aacttaaatg acgttcccta atccttctct ctgcttcagg actcatgctt ttctaggaaa      7320
     gtaaaaattt ggagaatcat ttctgtctgt cccaccttcc caggggcaga acaatttctg      7380
     ttgtgttcta aggtgtgagt gcatgggagt agtattccta aaattcatac ttggtttcct      7440
     catgtaccca actctgtccc tttatctatg catattgctt taaatcatat ttttctgtca      7500
     aggtgtacaa ggatgataaa taggtgccaa gtggagcact caagtgtgat gagtgccctc      7560
     acagtggaat ggagtgagaa gctttctgac ctcataaact gaaggctatc ttcagtcatt      7620
     gttttatata ttttacgtgc attaatcctc atataacccc aagaggtaaa ttagtataat      7680
     tatccttcat tgtaggtgac aaagttgaga cacagaagaa tcaaaaaact cttccaggat      7740
     caaccagtaa aaggcagacc ttggattcga accaggcaac ctggctcaaa tatcagtttt      7800
     aattactaca ctctgtactt tccaagattt gtaaacagtt tgacaatgca tgccgattta      7860
     aaactatgaa gaaacaaaca caatttttca caacacctct caaatctaat gggtcctcac      7920
     tgtcaagatt aaattccagg ctgatgacac tgtaaggtca catggccagc tgtgctatag      7980
     gcctggtcaa ggccagagcc tgggtttgca gagaagcaga cacacagcca aaccaggaga      8040
     cttactctgt cttcctgact cattccctct acgttgtttt tctcctagtc caacctaagg      8100
     tgactgtata tccttcaaag acccagcccc tgcagcacca caacctcctg gtctgctctg      8160
     tgagtggttt ctatccaggc agcattgaag tcaggtggtt cctgaacggc caggaagaga      8220
     aggctgggat ggtgtccaca ggcctgatcc agaatggaga ctggaccttc cagaccctgg      8280
     tgatgctgga aacagttcct cgaagtggag aggtttacac ctgccaagtg gagcacccaa      8340
     gcgtgacaag ccctctcaca gtggaatgga gtgagcagct ttctgacttc ctaaatttct      8400
     cacccactaa gaaggggacc gtgctaatcc ctgagtgtca ggttcctcct ctcccacatc      8460
     ctattttaat ttgctccatg ttctcatctc catcagcaca ggtcactggg ggtagccctg      8520
     taggtgtttc tagaaacacc tgtacctcct ggagaagcag tctcgcctgc caggcgggag      8580
     agactgtccc tcttttgaac ctccccatga ttttgcaggt cagggtcacc cactctccca      8640
     ggctccaggc cctgcctctg ggtctgagac tgagtttctg gtgctgttgc tctgagttat      8700
     tttttgtgat ctgggaagag gagaagtgta ggggcctacc tgacatgagg ggagtccaat      8760
     ctcagccctg ctttttatta gctttgtcac tctagacaaa ctacttatcc tcattgagtc      8820
     tcaggctttc tgtggatcag atgttgaact tgtgccttac atcaaggctg taatatttga      8880
     atgagtttga tgtctgaacg tcgtaactgt tcagtgtaat ttgaaatcct ttttttctcc      8940
     tgaaatggct agttatttta gttcttgtga ggcagctttc tgccccattt tcaaagctct      9000
     aaatcttaga gtctcaagta aaaaggttca atttggaata aacatcacta aacctggctt      9060
     cctctctcag gagcacggtc tgaatctgca cagagcaaga tgctgagtgg agtcgggggc      9120
     tttgtgctgg gcctgctctt ccttggggcc gggctgttca tctacttcag gaatcagaaa      9180
     ggtgaggagc ctttgggagc tggctctctc cataggcttt tctggaggag gaactatggc      9240
     tttgctgagg ttagttctca gtatatgagt ggccctgaat aaagcctttc tttccccaaa      9300
     cggctctaat gtcctgctaa tccagaaatc atcagtgcat ggttactatg tgaaagcata      9360
     atagcttgtg gcctgcagag acgagaggaa ggttaacaag taggggtcct ttggtttgag      9420
     atcttggagc aaattaagga agagccacta aggctaatgg aattacactg gatcctgtga      9480
     cagacacttc aggcttcatg ggtcacatgg tctgtttctg ctcctttctg ccctggttgg      9540
     tgtgggttgt ggtgttagag aaatctcagg tgggagatct ggggctggga cattgtgttg      9600
     gaggacagat ttgcttcaat aacttttaag tgtatatctt ttcctctttt tcccaggaca      9660
     ctctggactt cagccaacag gtaatacctt ttaatcctct tttagaaaca gacacagttt      9720
     ccctagtgag aggtgaagcc agctggactt ctgggtgggg tggggacttg gagaactttt      9780
     cttacaagag gttttttttt gttttttttt tttttttttt ttttgagacg gagtctcgct      9840
     ctgtcgccca ggctggagtg cagtggcggg atctcggctc actgcaagct ccgcctcccg      9900
     ggttcacgcc attctcctgc ctcagcctcc caagtagctg ggactacagg cgcccgccac      9960
     tacgcccggc taattttttg tatttttagt agagacgggg tttcaccgtt ttagccagga     10020
     tggtctcgat ctcctgacct cgtgatccgc ccgcctcggc ctcccaaagt gctgggatta     10080
     caggcgtgag ccaccgcgcc cggcctacaa gaggtttcta aatgcaccaa tcagtgcttt     10140
     gtaaaaacac accaataggt tctctgtggc tagctggatg tttgtaaaat ggaccaattc     10200
     gcactctgta aaatagacca atcagcactc tttaaaatgg accaatcagc acttttaaaa     10260
     tgggccaatc accactcttt aaaatggacc aatcagcact ctttaaaatg gaccaatctg     10320
     caggacatgg gcagggacaa atacaggaat aaaagctggc caccccaacc agcagtggca     10380
     acccactcag gtcctcttcc ctgctgtgga agttttgttc ttttgatctt cacaataaat     10440
     cttgctgctg cccactcttt ggatccctgc cgcctttaag agctgtaaca ctcactgtga     10500
     aggtctgcag gaagtcagcg agaccacaaa cccaccggaa ggaacaaact caggacacac     10560
     cagaatgatg gtagaggtga taaggcatga gacagaaata ataggaaaga ctttggatcc     10620
     aaatttctga tcaggcaatt tacaccaaaa ttcctcctct ccacttagaa aaggtgtgct     10680
     ctgcgggact attggctcag gggagactca ggaacttctt tttcttcttc ctgcagtgct     10740
     ctcatctgag cccttgaaag aggggaaaag aaactgttag tagagccagg ttgaaaacaa     10800
     cactctcctc tgtcttttgc aggattcctg agctgaaatg cagatgacca cattcaagga     10860
     agaactttct gccccggctt tgcaggatga aaagctttcc tgcttggcag ttattcttcc     10920
     acaagagagg gctttctcag gacctggttg ctactggttc ggcaactgca gaaaatgtcc     10980
     tcccttgtgg cttcctcagc tcctgccctt ggcctgaagt cccagcattg atggcagcgc     11040
     ctcatcttca actttt                                                     11056
//


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