Dbfetch
ID GQ373181; SV 1; linear; genomic DNA; STD; HUM; 1858 BP. XX AC GQ373181; XX DT 19-AUG-2009 (Rel. 101, Created) DT 10-DEC-2009 (Rel. 103, Last updated, Version 2) XX DE Homo sapiens MHC class I antigen (HLA-Cw) gene, HLA-Cw*01 variant allele, DE exons 1 through 4 and partial cds. XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-1858 RX DOI; 10.1111/j.1399-0039.2009.01384.x. RX PUBMED; 19804560. RA Deng Z.-H., Wang D.-M.; RT "A novel HLA-Cw*01 variant allele, HLA-Cw*0130"; RL Tissue Antigens 74(6):549-551(2009). XX RN [2] RP 1-1858 RA Deng Z., Wang D., Xu Y.; RT "Identification of a novel HLA-Cw*01 variant allele with codon 171 TAC>CAC RT missense mutation on the Cw*010201 basis"; RL Unpublished. XX RN [3] RP 1-1858 RA Deng Z., Wang D., Xu Y.; RT ; RL Submitted (10-JUL-2009) to the INSDC. RL Immunogenetics Laboratory, Shenzhen Blood Center, Nigang Xi Road, Meigang RL Nan Street, Shenzhen, Guangdong 518035, China XX DR MD5; 50002820eb19b504175d9f98398f843a. DR IMGT/HLA; HLA-C*01:30; HLA04020. XX FH Key Location/Qualifiers FH FT source 1..1858 FT /organism="Homo sapiens" FT /chromosome="6" FT /map="6p21.31" FT /mol_type="genomic DNA" FT /PCR_primers="fwd_seq: ccaatcagcgtctccgcagtc, rev_seq: FT accccycatycccctccttac" FT /note="Chinese Han individual" FT /db_xref="taxon:9606" FT gene <1..>1858 FT /gene="HLA-Cw" FT /allele="HLA-Cw*01 variant" FT mRNA join(<1..73,204..473,720..995,1583..>1858) FT /gene="HLA-Cw" FT /allele="HLA-Cw*01 variant" FT /product="MHC class I antigen" FT CDS join(1..73,204..473,720..995,1583..>1858) FT /codon_start=1 FT /gene="HLA-Cw" FT /allele="HLA-Cw*01 variant" FT /product="MHC class I antigen" FT /db_xref="InterPro:IPR001039" FT /db_xref="InterPro:IPR003006" FT /db_xref="InterPro:IPR003597" FT /db_xref="InterPro:IPR007110" FT /db_xref="InterPro:IPR011161" FT /db_xref="InterPro:IPR011162" FT /db_xref="InterPro:IPR013783" FT /db_xref="InterPro:IPR036179" FT /db_xref="InterPro:IPR037055" FT /db_xref="UniProtKB/TrEMBL:C8C9X1" FT /protein_id="ACU43582.1" FT /translation="MRVMAPRTLILLLSGALALTETWACSHSMKYFFTSVSRPGRGEPR FT FISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRVSLRN FT LRGYYNQSEAGSHTLQWMCGCDLGPDGRLLRGYDQYAYDGKDYIALNEDLRSWTAADTA FT AQITQRKWEAAREAEQRRAYLEGTCVEWLRRHLENGKETLQRAEHPKTHVTHHPVSDHE FT ATLRCWALGFYPAEITLTWQWDGEDQTQDTELVETRPAGDGTFQKWAAVMVPSGEEQRY FT TCHVQHEGLPEPLTLRW" FT exon <1..73 FT /gene="HLA-Cw" FT /allele="HLA-Cw*01 variant" FT /number=1 FT exon 204..473 FT /gene="HLA-Cw" FT /allele="HLA-Cw*01 variant" FT /number=2 FT exon 720..995 FT /gene="HLA-Cw" FT /allele="HLA-Cw*01 variant" FT /number=3 FT variation 959 FT /gene="HLA-Cw" FT /replace="t" FT /note="results in Tyr to His substitution" FT exon 1583..1858 FT /gene="HLA-Cw" FT /allele="HLA-Cw*01 variant" FT /number=4 XX SQ Sequence 1858 BP; 350 A; 571 C; 611 G; 326 T; 0 other; atgcgggtca tggcgccccg aaccctcatc ctgctgctct cgggagccct ggccctgacc 60 gagacctggg cctgtgagtg cggggttggg agggaaacgg cctctgcgga gaggaacgag 120 gtgcccgccc ggcgagggcg caggacccgg ggagccgcgc agggaggagg gtcgggcggg 180 tctcagcccc tcctcgcccc caggctccca ctccatgaag tatttcttca catccgtgtc 240 ccggcctggc cgcggagagc cccgcttcat ctcagtgggc tacgtggacg acacgcagtt 300 cgtgcggttc gacagcgacg ccgcgagtcc gagaggggag ccgcgggcgc cgtgggtgga 360 gcaggagggg ccggagtatt gggaccggga gacacagaag tacaagcgcc aggcacagac 420 tgaccgagtg agcctgcgga acctgcgcgg ctactacaac cagagcgagg ccggtgagtg 480 accccggccc ggggcgcagg tcacgacccc tcctcatccc ccacggacgg cccgggtcgc 540 cccaagtctc ccggtctgag atccaccccg aggctgcgga acccgcccag accctcgacc 600 ggagagagcc ccagtcacct ttacccggtt tcattttcag tttaggccaa aatccccgcg 660 ggttggtcgg gactggggcg gggctcgggg gacggggctg accacggggg cggggccagg 720 gtctcacacc ctccagtgga tgtgtggctg cgacctgggg cccgacgggc gcctcctccg 780 cgggtatgac cagtacgcct acgacggcaa ggattacatc gccctgaacg aggacctgcg 840 ctcctggacc gccgcggaca ccgcggctca gatcacccag cgcaagtggg aggcggcccg 900 tgaggcggag cagcggagag cctacctgga gggcacgtgc gtggagtggc tccgcagaca 960 cctggagaac gggaaggaga cgctgcagcg cgcgggtacc aggggcagtg gggagccttc 1020 cccatctccc gtagatctcc cggcatggcc tcccacgagg aggggaggaa aatgggatca 1080 gcgctagaat atcgccctcc cttgaatgga gaatgggatg agttttcctg agtttcctct 1140 gagggccccc tctgctctct aggacaatta agggatgaag tccttgagga aatggagggg 1200 aagacagtcc ctggaatact gatcaggggt cccctttgac cactttgacc actgcagcag 1260 ctgtggtcag gctgctgacc tttctctcag gccttgttct ctgcctcacg ctcaatgtgt 1320 ttgaaggttt gattccagct tttctgagtc cttcggcctc cactcaggtc aggaccagaa 1380 gtcgctgttc ctccctcaga gactagaact ttccaatgaa taggagatta tcccaggtgc 1440 ctgtgtccag gctggcgtct gggttctgtg cccccttccc caccccaggt gtcctgtcca 1500 ttctcaggat ggtcacatgg gcgctgttgg agtgtcgcaa gagagataca aagtgtctga 1560 attttctgac tcttcccgtc agaacaccca aagacacacg tgacccacca tcccgtctct 1620 gaccatgagg ccaccctgag gtgctgggcc ctgggcttct accctgcgga gatcacactg 1680 acctggcagt gggatgggga ggaccaaact caggacaccg agcttgtgga gaccaggcca 1740 gcaggagatg gaaccttcca gaagtgggca gctgtgatgg tgccttctgg agaagagcag 1800 agatacacgt gccatgtgca gcacgagggg ctgccggagc ccctcaccct gagatggg 1858 //