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EBI Dbfetch

ID   FN999910; SV 2; linear; genomic DNA; STD; HUM; 3086 BP.
XX
AC   FN999910;
XX
DT   11-APR-2011 (Rel. 108, Created)
DT   26-APR-2012 (Rel. 112, Last updated, Version 3)
XX
DE   Homo sapiens HLA-C gene for MHC class I antigen, HLA-C*04:71 allele
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RC   revised by [3]
RA   Vilches C.;
RT   ;
RL   Submitted (08-JUL-2010) to the INSDC.
RL   Vilches C., H.U. Puerta de Hierro, Immunogentics-HLA lab, Manuel de Falla
RL   1, 28222, SPAIN.
XX
RN   [2]
RX   DOI; 10.1111/j.1399-0039.2011.01833.x.
RX   PUBMED; 22251067.
RA   Moraru M., Balas A., de Pablo R., Vicario J.L., Vilches C.;
RT   "Allele-specific amplification of the complete HLA-C gene from genomic DNA
RT   - a novel Cw4 allele (C*04:71) with a Cw1 motif in the peptide-binding
RT   site";
RL   Tissue Antigens 79(4):291-294(2012).
XX
RN   [3]
RP   1-3086
RA   Vilches C.;
RT   ;
RL   Submitted (14-APR-2011) to the INSDC.
RL   Vilches C., H.U. Puerta de Hierro, Immunogentics-HLA lab, Manuel de Falla
RL   1, 28222, SPAIN.
XX
DR   MD5; 02b46fcce463bf80c626c51f5d36bab3.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..3086
FT                   /organism="Homo sapiens"
FT                   /chromosome="6"
FT                   /map="6p21"
FT                   /mol_type="genomic DNA"
FT                   /country="Spain"
FT                   /tissue_type="blood"
FT                   /db_xref="taxon:9606"
FT   exon            <1..93
FT                   /gene="HLA-C"
FT                   /allele="HLA-C*04:71"
FT                   /number=1
FT   CDS             join(21..93,224..493,740..1015,1603..1878,2000..2119,
FT                   2559..2591,2699..2746,2911..2915)
FT                   /gene="HLA-C"
FT                   /allele="HLA-C*04:71"
FT                   /product="MHC class I antigen"
FT                   /function="antigen presenting molecule"
FT                   /db_xref="GOA:F4MKW1"
FT                   /db_xref="IMGT/HLA:C*04:71"
FT                   /db_xref="InterPro:IPR001039"
FT                   /db_xref="InterPro:IPR003006"
FT                   /db_xref="InterPro:IPR003597"
FT                   /db_xref="InterPro:IPR007110"
FT                   /db_xref="InterPro:IPR010579"
FT                   /db_xref="InterPro:IPR011161"
FT                   /db_xref="InterPro:IPR011162"
FT                   /db_xref="InterPro:IPR013783"
FT                   /db_xref="InterPro:IPR027648"
FT                   /db_xref="UniProtKB/TrEMBL:F4MKW1"
FT                   /protein_id="CBS91672.2"
FT                   /translation="MRVMAPRTLILLLSGALALTETWAGSHSMRYFFTSVSWPGRGEPR
FT                   FIAVGYVDDTQFVRFDSDAASPRGEPREPWVEQEGPEYWDRETQKYKRQAQADRVNLRK
FT                   LRGYYNQSEDGSHTLQRMFGCDLGPDGRLLRGYNQFAYDGKDYIALNEDLRSWTAADTA
FT                   AQITQRKWEAAREAEQRRAYLEGTCVEWLRRYLENGKETLQRAEHPKTHVTHHPVSDHE
FT                   ATLRCWALGFYPAEITLTWQWDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRY
FT                   TCHVQHEGLPEPLTLRWKPSSQPTIPIVGIVAGLAVLAVLAVLGAMVAVVMCRRKSSGG
FT                   KGGSCSQAASSNSAQGSDESLIACKA"
FT   exon            224..493
FT                   /gene="HLA-C"
FT                   /allele="HLA-C*04:71"
FT                   /number=2
FT   exon            740..1015
FT                   /gene="HLA-C"
FT                   /allele="HLA-C*04:71"
FT                   /number=3
FT   exon            1603..1878
FT                   /gene="HLA-C"
FT                   /allele="HLA-C*04:71"
FT                   /number=4
FT   exon            2000..2119
FT                   /gene="HLA-C"
FT                   /allele="HLA-C*04:71"
FT                   /number=5
FT   exon            2559..2591
FT                   /gene="HLA-C"
FT                   /allele="HLA-C*04:71"
FT                   /number=6
FT   exon            2699..2746
FT                   /gene="HLA-C"
FT                   /allele="HLA-C*04:71"
FT                   /number=7
FT   exon            2911..>3086
FT                   /gene="HLA-C"
FT                   /allele="HLA-C*04:71"
FT                   /number=8
XX
SQ   Sequence 3086 BP; 583 A; 881 C; 978 G; 644 T; 0 other;
     gattctcccc agacgccgag atgcgggtca tggcgccccg aaccctcatc ctgctgctct        60
     cgggagccct ggccctgacc gagacctggg ccggtgagtg cggggttggg agggaaacgg       120
     cctctgggga gaggagcgag gggcccgccc ggcgagggcg caggacccgg ggagccgcgc       180
     agggaggagg gtcgggcggg tctcagccac tcctcgtccc caggctccca ctccatgagg       240
     tatttcttca catccgtgtc ctggcccggc cgcggggagc cccgcttcat cgcagtgggc       300
     tacgtggacg acacgcagtt cgtgcggttc gacagcgacg ccgcgagtcc aagaggggag       360
     ccgcgggagc cgtgggtgga gcaggagggg ccggagtatt gggaccggga gacacagaag       420
     tacaagcgcc aggcacaggc tgaccgagtg aacctgcgga aactgcgcgg ctactacaac       480
     cagagcgagg acggtgagtg accccggccc ggggcgcagg tcacgacccc tccccatccc       540
     ccacggacgg cccgggtcgc cccgagtctc cccgtctgag atccaccccg aggctgcgga       600
     acccgcccag accctcgacc ggagagagcc ccagtcacct ttacccggtt tcattttcag       660
     tttaggccaa aatccccgcg ggttggtcgg gactggggcg gggctcgggg gaccgggctg       720
     accacggggg cggggccagg gtctcacacc ctccagagga tgtttggctg cgacctgggg       780
     ccggacgggc gcctcctccg cgggtataac cagttcgcct acgacggcaa ggattacatc       840
     gccctgaacg aggatctgcg ctcctggacc gccgcggaca cggcggctca gatcacccag       900
     cgcaagtggg aggcggcccg tgaggcggag cagcggagag cctacctgga gggcacgtgc       960
     gtggagtggc tccgcagata cctggagaac gggaaggaga cgctgcagcg cgcgggtacc      1020
     aggggcagtg gggagccttc cccatctccc gtagatctcc cgggatggcc tcccacgagg      1080
     aggggaggaa aatgggatca gcgctagaat atcgccctcc cttgaatgga gaatgggatg      1140
     agttttcctg agtttcctct gagggccccc tctgctctct aggacaatta agggatgaag      1200
     tccttgagga aatggagggg aagacagtcc ctggaatact gatcaggggt cccctttgac      1260
     cactttgacc actgcagcag ctgtggtcag gctgctgacc tttctctcag gccttgttct      1320
     ctgcctgacg ctcaatgtgt ttgaaggttt gattccagct tttctgagtc cttcggcctc      1380
     cactcaggtc aggaccagaa gtcgctgttc ctccctcaga gactagaact ttccaatgaa      1440
     taggagatta tcccaggtgc ctgtgtccag gctggcgtct gggttctgtg cccccttccc      1500
     caccccaggt gtcctgtcca ttctcaggat ggtcacatgg gcgctgttgg agtgtcgcaa      1560
     gagagataca aagtgtctga attttctgac tcttcccatc agaacaccca aagacacacg      1620
     tgacccacca tcccgtctct gaccatgagg ccaccctgag gtgctgggcc ctgggcttct      1680
     accctgcgga gatcacactg acctggcagt gggatgggga ggaccaaact caggacaccg      1740
     agcttgtgga gaccaggcca gcaggagatg gaaccttcca gaagtgggca gctgtggtgg      1800
     tgccttctgg agaagagcag agatacacgt gccatgttca gcacgagggg ctgccggagc      1860
     ccctcaccct gagatggagt aaggaggggg atgaggggtg atgtgtcttc tcagggaaag      1920
     cagaagtcct ggagcccttc agccgggtca gggctgaggc ttggaggtca gggcccctca      1980
     ccttcccctc ctttcccaga gccgtcttcc cagcccacca tccccatcgt gggcatcgtt      2040
     gctggcctgg ctgtcctggc tgtcctagct gtcctaggag ctatggtggc tgttgtgatg      2100
     tgtaggagga agagctcagg tagggaaggg gtgaggagtg gggtctgggt tttcttgttc      2160
     cactgggagt ttcaagcccc aggtagaagt gtgccccacc tcgttactgg aagcaccatc      2220
     cacacgtggg ccatcccagc ctgggaccct gtgtgccagc acttactctg ttgtgaagca      2280
     catgacaatg aaggacagat gtatcacctt gatgattatg gtgttggggt ccttgattcc      2340
     agcattcatg agtcagggga aggtccctgc taaggacaga ccttaggagg gcagttgctt      2400
     cagaacccac agctgctttc cccgtgtttc ctgatcctgc cctgggtctg cagtcatagt      2460
     tctggaaact tctcttgggt ccaagactag gaggttcccc taagatcgca tggccctgcc      2520
     tcctccctgt cccctcacag ggcattttct tcccacaggt ggaaaaggag ggagctgctc      2580
     tcaggctgcg tgtaagtgat ggcggtgggc gtgtggagga gctcacccac cccataattc      2640
     ctcttgtccc acatctcctg cgggctctga ccaggtcttt ttttttgttc taccccagcc      2700
     agcaacagtg cccagggctc tgatgagtct ctcatcgctt gtaaaggtga gattctgggg      2760
     agctgaagtg gtcgggggtg gggcagaggg aaaaggccta ggtaatgggg atcctttgat      2820
     tgggacgttt cgaatgtgtg gtgagctgtt cagagtgtca tcacttacca tgactgacct      2880
     gaatttgttc atgactattg tgttctgtag cctgagacag ctgcctgtgt gggactgaga      2940
     tgcaggattt cttcacacct ctcctttgtg acttcaagag cctctggcat ctctttctgc      3000
     aaaggcatct gaatgtgtct gcgttcctgt tagcataatg tgaggaggtg gagagacagc      3060
     ccacccccgt gtccaccgtg acccct                                           3086
//


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