Dbfetch

ID   FJ868756; SV 1; linear; genomic DNA; STD; HUM; 787 BP.
XX
AC   FJ868756;
XX
DT   28-APR-2009 (Rel. 100, Created)
DT   28-APR-2009 (Rel. 100, Last updated, Version 1)
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DE   Homo sapiens nonfunctional MHC class I antigen (HLA-A) gene, HLA-A*74var
DE   allele, partial sequence.
XX
KW   .
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OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
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RN   [1]
RP   1-787
RA   Vigh A., Fuerst D., Mytilineos J.;
RT   "Characterization of a new HLA-A*74 allele";
RL   Unpublished.
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RN   [2]
RP   1-787
RA   Vigh A., Fuerst D., Mytilineos J.;
RT   ;
RL   Submitted (27-MAR-2009) to the INSDC.
RL   Transplantation Immunology, Institute for Clinical Transfusion Medicine and
RL   Immunogenetics Ulm, Helmholtzstrasse 10, Ulm 89081, Germany
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DR   MD5; dc50ff8c4618b1a51e2beaa7158c32c9.
DR   IMGT/HLA; A*74:14N; HLA03771.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..787
FT                   /organism="Homo sapiens"
FT                   /chromosome="6"
FT                   /map="6p21.3"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:9606"
FT   gene            <1..>787
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*74var"
FT   misc_feature    join(<1..270,512..>787)
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*74var"
FT                   /note="nonfunctional MHC class I antigen due to mutation"
FT   exon            1..270
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*74var"
FT                   /number=2
FT   variation       152
FT                   /gene="HLA-A"
FT                   /replace="g"
FT                   /note="compared to HLA-A*7403 allele; results in stop codon
FT                   to tryptophan (Trp) substitution"
FT   exon            512..787
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*74var"
FT                   /number=3
XX
SQ   Sequence 787 BP; 142 A; 249 C; 283 G; 113 T; 0 other;
     gctcccactc catgaggtat ttcttcacat ccgtgtcccg gcccggccgc ggggagcccc        60
     gcttcatcgc cgtgggctac gtggacgaca cgcagttcgt gcggtttgac agcgacgccg       120
     cgagccagag gatggagccg cgggcgccgt gaatagagca ggaggggccg gagtattggg       180
     accaggagac acggaatgtg aaggcccact cacagactga ccgagtggac ctggcgaccc       240
     tgcgcggcta ctacaaccag agcgaggccg gtgagtgacc ccggccgggg gcgcaggtca       300
     ggacccctca tcccccacgg acgggccagg tcgcccacag tctccgggtc cgagatccac       360
     cccgaagccg cgggaccccg agacccttgc cccgggagag gcccaggcgc ctttacccgg       420
     tttcattttc agtttaggcc aaaaatcccc ccgggttggt cggggccgga cggggctcgg       480
     gggactgggc tgaccgtggg gtcggggcca ggttctcaca ccatccagat gatgtatggc       540
     tgcgacgtgg ggccggacgg gcgcctcctc cgcgggtacc agcaggacgc ctacgacggc       600
     aaggattaca tcgccttgaa cgaggacctg cgctcttgga ccgcggcgga catggcggct       660
     cagatcaccc agcgcaagtg ggaggcggcc cgtgtggcgg agcagttgag agcctacctg       720
     gagggcacgt gcgtggagtg gctccgcaga tacctggaga acgggaagga gacgctgcag       780
     cgcacgg                                                                 787
//