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EBI Dbfetch

ID   FJ785727; SV 1; linear; genomic DNA; STD; HUM; 4536 BP.
XX
AC   FJ785727;
XX
DT   29-MAR-2009 (Rel. 100, Created)
DT   29-MAR-2009 (Rel. 100, Last updated, Version 1)
XX
DE   Homo sapiens MHC class I antigen (HLA-Cw) gene, HLA-Cw-Cw*080101 variant
DE   allele, promoter region and complete cds.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-4536
RA   Xu Y., Deng Z., Yang B.;
RT   "HLA-Cw full length cloning and sequencing: Sequence analysis from 5'
RT   upstream region through 3' downstream region";
RL   Unpublished.
XX
RN   [2]
RP   1-4536
RA   Xu Y., Deng Z., Yang B.;
RT   ;
RL   Submitted (23-FEB-2009) to the INSDC.
RL   Immunogenetic Laboratory, Shenzhen Blood Center, 2# Meigang South Street,
RL   Nigang West Road, Shenzhen, Guangdong 518035, China
XX
DR   MD5; 794db877aae5bf0b80f0e452bd986434.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..4536
FT                   /organism="Homo sapiens"
FT                   /chromosome="6"
FT                   /map="6p21.3"
FT                   /mol_type="genomic DNA"
FT                   /PCR_primers="fwd_name: CwF, fwd_seq:
FT                   cgcaactttgaggtgatgact, rev_name: CwR, rev_seq:
FT                   ttgtctcagaaagcacaggga"
FT                   /db_xref="taxon:9606"
FT   gene            1..4536
FT                   /gene="HLA-Cw"
FT                   /allele="Cw*080101 variant"
FT   misc_feature    1..961
FT                   /gene="HLA-Cw"
FT                   /allele="Cw*080101 variant"
FT                   /note="contains promoter and 5' UTR"
FT   mRNA            join(<962..1034,1165..1434,1681..1956,2544..2819,
FT                   2941..3060,3500..3532,3640..3687,3852..4536)
FT                   /gene="HLA-Cw"
FT                   /allele="Cw*080101 variant"
FT                   /product="MHC class I antigen"
FT   CDS             join(962..1034,1165..1434,1681..1956,2544..2819,2941..3060,
FT                   3500..3532,3640..3687,3852..3856)
FT                   /codon_start=1
FT                   /gene="HLA-Cw"
FT                   /allele="Cw*080101 variant"
FT                   /product="MHC class I antigen"
FT                   /note="glycoprotein"
FT                   /db_xref="GOA:C1K0X5"
FT                   /db_xref="IMGT/HLA:C*08:22"
FT                   /db_xref="InterPro:IPR001039"
FT                   /db_xref="InterPro:IPR003006"
FT                   /db_xref="InterPro:IPR003597"
FT                   /db_xref="InterPro:IPR007110"
FT                   /db_xref="InterPro:IPR010579"
FT                   /db_xref="InterPro:IPR011161"
FT                   /db_xref="InterPro:IPR011162"
FT                   /db_xref="InterPro:IPR013783"
FT                   /db_xref="InterPro:IPR027648"
FT                   /db_xref="UniProtKB/TrEMBL:C1K0X5"
FT                   /protein_id="ACN97193.1"
FT                   /translation="MRVMAPRTLILLLSGALALTETWACSHSMRYFYTAVSRPGRGEPR
FT                   FIAVGYVDDTQFVQFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRVSLRN
FT                   LRGYYNQSEAGSHTLQRMYGCDLGPDGRLLRGYNQFAYDGKDYIALNEDLRSWTAADTA
FT                   AQITQRKWEAARTAEQLRAYLEGTCVEWLRRYLENGKKTLQRAEHPKTHVTHHPVSDHE
FT                   ATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRY
FT                   TCHVQHEGLPEPLTLRWGPSSQPTIPIVGIVAGLAVLAVLAVLGAVMAVVMCRRKSSGG
FT                   KGGSYSQAASSNSAQGSDESLIACKA"
FT   variation       3518
FT                   /gene="HLA-Cw"
FT                   /replace="g"
FT                   /note="compared to allele Cw*080101"
FT   3'UTR           3857..4536
FT                   /gene="HLA-Cw"
FT                   /allele="Cw*080101 variant"
XX
SQ   Sequence 4536 BP; 934 A; 1245 C; 1346 G; 1011 T; 0 other;
     gcaactttga ggtgatgact acaggctccc ggttgcaata gacagtaaca aaccctgctt        60
     ctttgtattc aggagatgtt ctggactcac acaaggaaac tcgggctaga gaatgaggat       120
     aactttaaat gcaacaaccc agagtcacag atccatagtc tgcgaaagta aaacaggagc       180
     tttgagaatt taattgtaat gcagttttga cacaggtctt tcacagattg gaattctaat       240
     cattcaggga ttaccaatat tgtgctacct actgtatcaa taaacaaaaa ggaaactggt       300
     ctctatgaga atctctacct ggtgctttca gacaaaactt caccaggttt aaagagaaaa       360
     ctcctgactc tacacgtcca ttcccagggc gagctcactg tctggcatca agttccccat       420
     ggtgagtttc cctgtacaag agtccaaggg gagaggtaag tgtcctttat tttgctggat       480
     gtagtttaat attacctgag gtaaggtaag gcaaagagtg ggaggcaggg agtccagttc       540
     agggacgggg attccaggag aagtgaaggg gaaggggctg ggcgcagcct gggggtctct       600
     ccctggtttc cacagacaga tccttggcca ggactcaggc acacagtgtg acaaagatgc       660
     ttggtgtagg agaagaggga tcaggacgaa gtcccaggtc ccgggcgggg ctctcagggt       720
     ctcaggctcc aagggccgtg tctgcactgg ggaggcgccg cgttgaggat tctccactcc       780
     cctgagtttc acttcttctt ccaacctgcg tcgggtcctt cttcctgaat actcatgacg       840
     cgtccccaat tcccactccc attgggtgtc gggttctaga gaagccaatc agcgtctccg       900
     cagtcccggt tctaaagtcc ccagtcaccc acccggactc ggattctccc cagacgccga       960
     gatgcgggtc atggcgcccc gaaccctcat cctgctgctc tcgggagccc tggccctgac      1020
     cgagacctgg gcctgtgagt gcgaggttgg gagggaaacg gcctctgcgg agaggagcga      1080
     ggggcccgcc cggcgagggc gcaggacccg gggagccgcg cagggaggag ggtcgggcgg      1140
     gtctcagccc ctcctcgccc ccaggctccc actccatgag gtatttctac accgccgtgt      1200
     cccggcccgg ccgcggagag ccccgcttca tcgcagtggg ctacgtggac gacacgcagt      1260
     tcgtgcagtt cgacagcgac gccgcgagtc caagagggga gccgcgggcg ccgtgggtgg      1320
     agcaggaggg gccggagtat tgggaccggg agacacagaa gtacaagcgc caggcacaga      1380
     ctgaccgagt gagcctgcgg aacctgcgcg gctactacaa ccagagcgag gccggtgagt      1440
     gaccccggcc cggggcgcag gtcccgaccc ctccccatcc cccacggacg gcccgggtcg      1500
     ccccgagtct cccggtctga gatccacccc gaggctgcgg aacccgccca gaccctcgac      1560
     cggagagagc cccagtcacc tttacccggt ttcattttca gtttaggcca aaatccccgc      1620
     gggttggtcg gggctggggc ggggctcggg ggacggggct gaccacgggg gcggggccag      1680
     ggtctcacac cctccagagg atgtatggct gcgacctggg gcccgacggg cgcctcctcc      1740
     gcgggtataa ccagttcgcc tacgacggca aggattacat cgccctgaat gaggacctgc      1800
     gctcctggac cgccgcggac acggcggctc agatcaccca gcgcaagtgg gaggcggccc      1860
     gtacggcgga gcagctgaga gcctacctgg agggcacgtg cgtggagtgg ctccgcagat      1920
     acctggagaa cgggaagaag acgctgcagc gcgcgggtac caggggcagt ggggagcctt      1980
     ccccatctcc tgtagatctc ccgggatggc ctcccacgag gaggggagga aaatgggatc      2040
     agcgctggaa tatcgccctc ccttgaatgg agaatgggat gagttttcct gagtttcctc      2100
     tgagggcccc ctctgctctc taggacaatt aagggatgaa gtccttgagg aaatggaggg      2160
     gaagacagtc cctggaatac tgatcagggg tcccctttga ccactttgac cactgcagca      2220
     gctgtggtca ggctgctgac ctttctctca ggccttgttc tctgcctcac gctcaatgtg      2280
     tttaaaggtt tgattccagc ttttctgagt ccttcggcct ccactcaggt caggaccaga      2340
     agtcgctgtt cctccctcag agactagaac tttccaatga ataggagatt atcccaggtg      2400
     cctgtgtcca ggctggcgtc tgggttctgt gcccccttcc ccaccccagg tgtcctgtcc      2460
     attctcagga tggtcacatg ggcactgttg gagtgtcgca agagagatac aaagtgtctg      2520
     aattttctga ctcttcccgt cagaacaccc aaagacacac gtgacccacc atcccgtctc      2580
     tgaccatgag gccaccctga ggtgctgggc cctgggcttc taccctgcgg agatcacact      2640
     gacctggcag cgggatggcg aggaccaaac tcaggacacc gagcttgtgg agaccaggcc      2700
     agcaggagat ggaaccttcc agaagtgggc agctgtggtg gtgccttctg gagaagagca      2760
     gagatacacg tgccatgtgc agcacgaggg gctgccagag cccctcaccc tgagatgggg      2820
     taaggagggg gatgaggggt catgtgtctt ctcagggaaa gcagaagtcc tggagccctt      2880
     cagccgggtc agggctgagg cttgggggtc agggcccctc accttcccct cctttcccag      2940
     ggccatcttc ccagcccacc atccccatcg tgggcatcgt tgctggcctg gctgtcctgg      3000
     ctgtcctagc tgtcctagga gctgtgatgg ctgttgtgat gtgtaggagg aagagctcag      3060
     gtagggaagg ggtgaggagt ggggtctggg ttttcttgtc ccactgggag tttcaagccc      3120
     caggtagaag tgtgccccac ctcgttactg gaagcaccat ccacacatgg gccatcccag      3180
     cctgggaccc tgtgtgctag cacttactct gttgtgaagc acatgacaat gaaggacaga      3240
     tgtatcacct tgatgattat ggtgttgggg tccttgattc cagcattcat gagtcagggg      3300
     aaggtccctg ctaaggacag accttaggag ggcagttgct ccagaaccca cagctgcttt      3360
     ccccgtgttt cctgatcctg ccctgggtct gcagtcatag ttctggaaac ttctcttggg      3420
     tccaagacta ggaggttccc ctaagatcgc atggccctgc ctcctccctg tcccctcaca      3480
     gggcattttc ttcccacagg tggaaaagga gggagctact ctcaggctgc gtgtaagtga      3540
     tggcggtggg cgtgtggagg agctcaccca ccccataatt cctcttgtcc cacatctcct      3600
     gcgggctctg accaggtctt tttttttgtt ctaccccagc cagcaacagt gcccagggct      3660
     ctgatgagtc tctcatcgct tgtaaaggtg agattctggg gagctgaagt ggtcgggggt      3720
     ggggcagagg gaaaaggcct aggtaatggg gatcctttga ttgggacgtt tcgaatgtgt      3780
     ggtgagctgt tcagagtgtc atcacttacc atgactgacc tgaatttgtt catgactatt      3840
     gtgttctgta gcctgagaca gctgcctgtg tgggactgag atgcaggatt tcttcacacc      3900
     tttcctttgt gacttcaaga gcctctggca tctctttctg caaaggcatc tgaatgtgtc      3960
     tgcgttcctg ttagcataat gtgaggaggt ggagagacag cccacccccg tgtccaccgt      4020
     gacccctgtc cccacactga cctgtgttcc ctccccgatc atctttcctg ttccagagaa      4080
     gtgggctgga tgtctccatc tctgtctcaa ctttacgtgt actgagctgc aacttcttac      4140
     ttccctactg aaaataagaa tctgaatata aatttgtttt ctcaaatatt tgctatgaga      4200
     ggttgatgga ttaattaaat aagtcaattc ctggaagttg agagagcaaa taaagacctg      4260
     agaaccttcc agaatccgca tgttcgctgt gctgagtctg ttgcaggtgg gggtggggaa      4320
     ggctgtgagg agacgagtgt ggacggggcc tgtgcctagt tgctgttcag ttcttcatgg      4380
     gctttatgtg gtcagtcctc agctgggtca ccttcactgc tccattgtcc ttgtcccttc      4440
     agtggaaact tgtccagcgg gagctgtgac cacagaggct cacacatcgc ccagggcagc      4500
     ccctgcacac gggagtccct gtgctttctg agacaa                                4536
//


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