Dbfetch
ID DQ899174; SV 1; linear; genomic DNA; STD; HUM; 3090 BP. XX AC DQ899174; XX DT 29-AUG-2006 (Rel. 88, Created) DT 17-JUN-2008 (Rel. 96, Last updated, Version 4) XX DE Homo sapiens nonfunctional MHC class I antigen (HLA-A) gene, HLA-A*31 null DE allele, complete sequence. XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-3090 RX DOI; 10.1111/j.1399-0039.2006.00700.x. RX PUBMED; 17176446. RA Smith D.M., Gardner W.B., Baker J.E., Cox S.T., Kresie L.A.; RT "A new HLA-A*31 null allele, A*3114N"; RL Tissue Antigens 68(6):526-527(2006). XX RN [2] RP 1-3090 RA Smith D.M., Gardner W.B., Baker J.E., Kresie L.A.; RT ; RL Submitted (30-JUL-2006) to the INSDC. RL Pathology, Baylor University Medical Center, 3500 Gaston Ave, Dallas, TX RL 75246, USA XX RN [3] RP 1-3090 RA Cox S.T.; RT ; RL Submitted (22-AUG-2006) to the INSDC. RL The Royal Free Hospital, Anthony Nolan Research Institute, London NW3 2PF, RL UK XX DR MD5; afc943d7553ef55e21a855f5e266c8a8. DR IMGT/HLA; HLA-A*31:14N; HLA02651. XX FH Key Location/Qualifiers FH FT source 1..3090 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT gene <1..>2919 FT /gene="HLA-A" FT /allele="HLA-A*31 null" FT misc_feature join(1..73,203..472,714..989,1590..1866,1966..2082, FT 2523..2555,2698..2745,2915..2919) FT /gene="HLA-A" FT /allele="HLA-A*31 null" FT /note="nonfunctional MHC class I antigen due to frameshift FT mutation in exon 4" FT exon 1..73 FT /gene="HLA-A" FT /allele="HLA-A*31 null" FT /number=1 FT exon 203..472 FT /gene="HLA-A" FT /allele="HLA-A*31 null" FT /number=2 FT exon 714..989 FT /gene="HLA-A" FT /allele="HLA-A*31 null" FT /number=3 FT exon 1590..1866 FT /gene="HLA-A" FT /allele="HLA-A*31 null" FT /number=4 FT exon 1966..2082 FT /gene="HLA-A" FT /allele="HLA-A*31 null" FT /number=5 FT exon 2523..2555 FT /gene="HLA-A" FT /allele="HLA-A*31 null" FT /number=6 FT exon 2698..2745 FT /gene="HLA-A" FT /allele="HLA-A*31 null" FT /number=7 FT exon 2915..>2919 FT /gene="HLA-A" FT /allele="HLA-A*31 null" FT /number=8 XX SQ Sequence 3090 BP; 598 A; 878 C; 949 G; 665 T; 0 other; atggccgtca tggcgccccg aaccctcctc ctgctactct tgggggccct ggccctgacc 60 cagacctggg cgggtgagtg cggggtcgtg gggaaaccgc ctctgcgggg agaagcaagg 120 ggcccgcccg gcgggggcgc aggacccggg tagccgcgcc gggaggaggg tcgggcggat 180 ctcagccact cctcgccccc aggctcccac tccatgaggt atttcaccac atccgtgtcc 240 cggcccggcc gcggggagcc ccgcttcatc gccgtgggct acgtggacga cacgcagttc 300 gtgcggttcg acagcgacgc cgcgagccag aggatggagc cgcgggcgcc gtggatagag 360 caggagaggc ctgagtattg ggaccaggag acacggaatg tgaaggccca ctcacagatt 420 gaccgagtgg acctggggac cctgcgcggc tactacaacc agagcgaggc cggtgagtga 480 ccccagcccg gggcgcaggt cacgacctct catcccccac ggacgggcca ggtcacccac 540 agtctccggg tccgagatcc accccgaagc cgcgggaccc cgagaccctt gccccgggag 600 aggcccaggc gcctttaccc ggtttcattt tcagtttagg ccaaaaatcc ccccgggttg 660 gtcggggccg gacggggctc gggggactgg gctgaccgtg gggtcggggc caggttctca 720 caccatccag atgatgtatg gctgcgacgt ggggtcggac gggcgcttcc tccgcgggta 780 ccagcaggac gcctacgacg gcaaggatta catcgccttg aacgaggacc tgcgctcttg 840 gaccgcggcg gacatggcgg ctcagatcac ccagcgcaag tgggaggcgg cccgtgtggc 900 ggagcagttg agagcctacc tggagggcac gtgcgtggag tggctccgca gatacctgga 960 gaacgggaag gagacgctgc agcgcacggg taccaggggc cacggggcgc ctccctgatc 1020 gcctgtagat ctcccgggct ggcctcccac aaggagggga gacaattggg accaacacta 1080 gaatatcacc ctccctctgg tcctgaggga gaggaatcct cctgggtttc cagatcctgt 1140 accagagagt gactctgagg ttccgccctg ctctgtgaca caattaaggg ataaaatctc 1200 tgaaggaatg acgggaagac gatccctcga atactgatga gtggttccct ttgacacaca 1260 ccggcagcag ccttgggccc gtgacttttc ctctcaggcc ttgttctctg cttcacactc 1320 aatgtgtgtg ggggtctgag tccagcactt ctgagtccct cagcctccac tcaggtcagg 1380 accagaagtc gctgttccct cttcagggac tagaattttc cacggaatag gagattatcc 1440 caggtgcctg tgtccaggct ggtgtctggg ttctgtgctc ccttccccat cccaggtgtc 1500 ctgtccattc tcaagatagc cacatgtgtg ctggaggagt gtcccattac agatgcaaaa 1560 tgcctgaatg ttctgactct tcctgacaga ccccccccaa gacgcatatg actcaccacg 1620 ctgtctctga ccatgaggcc accctgaggt gctgggccct gagcttctac cctgcggaga 1680 tcacactgac ctggcagcgg gatggggagg accagaccca ggacacggag ctcgtggaga 1740 ccaggcctgc aggggatgga accttccaga agtgggcgtc tgtggtggtg ccttctggac 1800 aggagcagag atacacctgc catgtgcagc atgagggtct ccccaagccc ctcaccctga 1860 gatggggtaa ggagggagat gggggtgtca tgtcttttag ggaaagcagg agcctctctg 1920 acctttagca gggtcagggc ccctcacctt cccctctttt cccagagccg tcttcccagc 1980 ccaccatccc catcgtgggc atcattgctg gcctagttct ctttggagct gtgttcgctg 2040 gagctgtggt cgctgctgtg aggtggagga ggaagagctc aggtggggtg aaggggtgaa 2100 gggtgggtct gagatttctt gtctcactga gggttccaag acccaggtag aagtgtgccc 2160 tgcctcgtta ctgggaagca ccatccacaa ttatgggcct acccagcctg ggccctgtgt 2220 gccagcactt actcttttgt aaagcacctg ttaaaatgaa ggacagattt atcaccttga 2280 ttatggcggt gatgggacct gatcccagca gtcacaagtc acaggggaag gtccctgagg 2340 accttcagga gggcggttgg tccaggaccc acacctgctt tcttcatgtt tcctgatccc 2400 gccctgggtc tgcagtcaca catttctgga aacttctctg aggtccaaga cttggaggtt 2460 cctctaggac cttaaggccc tggctccttt ctggtatctc acaggacatt ttcttcccac 2520 agatagaaaa ggagggagct actctcaggc tgcaagtaag tatgaaggag gatgatccaa 2580 gaaatcactg ggatattgtg tttgggagcc cgtgggggag ctcacccacc ccacaattcc 2640 tcctctagcc acatcttctg tgggatctga ccaggttctg tttttgtcct accccaggca 2700 gtgacagtgc ccagggctct gatatgtctc tcacagcttg taaaggtgag agcctggagg 2760 gcctgatgtg tgttgggtgt tgggcggaac agtggacgca gctgtgctat ggggtttctt 2820 tgcattggat gtattgagca tgcgatgggc tgtttaaagt gtgactcctc actgtgacag 2880 atacgaattt gttcatgaat atttttttct atagtgtgag acagctgcct tgtgtgggac 2940 tgagaggcaa gatttgttcc tgcccttccc tttgtgactt gaagtaccct gactttgttt 3000 ctgcaaaggc acctgcatgt gtctgtgttc ttgtaggcat aatgtgagga ggtggggaga 3060 ccaccccacc cccatgtcca ccatgaccct 3090 //