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EBI Dbfetch

ID   DQ899174; SV 1; linear; genomic DNA; STD; HUM; 3090 BP.
XX
AC   DQ899174;
XX
DT   29-AUG-2006 (Rel. 88, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 4)
XX
DE   Homo sapiens nonfunctional MHC class I antigen (HLA-A) gene, HLA-A*31 null
DE   allele, complete sequence.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-3090
RX   DOI; 10.1111/j.1399-0039.2006.00700.x.
RX   PUBMED; 17176446.
RA   Smith D.M., Gardner W.B., Baker J.E., Cox S.T., Kresie L.A.;
RT   "A new HLA-A*31 null allele, A*3114N";
RL   Tissue Antigens 68(6):526-527(2006).
XX
RN   [2]
RP   1-3090
RA   Smith D.M., Gardner W.B., Baker J.E., Kresie L.A.;
RT   ;
RL   Submitted (30-JUL-2006) to the INSDC.
RL   Pathology, Baylor University Medical Center, 3500 Gaston Ave, Dallas, TX
RL   75246, USA
XX
RN   [3]
RP   1-3090
RA   Cox S.T.;
RT   ;
RL   Submitted (22-AUG-2006) to the INSDC.
RL   The Royal Free Hospital, Anthony Nolan Research Institute, London NW3 2PF,
RL   UK
XX
DR   MD5; afc943d7553ef55e21a855f5e266c8a8.
DR   IMGT/HLA; A*31:14N; HLA02651.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..3090
FT                   /organism="Homo sapiens"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:9606"
FT   gene            <1..>2919
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*31 null"
FT   misc_feature    join(1..73,203..472,714..989,1590..1866,1966..2082,
FT                   2523..2555,2698..2745,2915..2919)
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*31 null"
FT                   /note="nonfunctional MHC class I antigen due to frameshift
FT                   mutation in exon 4"
FT   exon            1..73
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*31 null"
FT                   /number=1
FT   exon            203..472
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*31 null"
FT                   /number=2
FT   exon            714..989
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*31 null"
FT                   /number=3
FT   exon            1590..1866
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*31 null"
FT                   /number=4
FT   exon            1966..2082
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*31 null"
FT                   /number=5
FT   exon            2523..2555
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*31 null"
FT                   /number=6
FT   exon            2698..2745
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*31 null"
FT                   /number=7
FT   exon            2915..>2919
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*31 null"
FT                   /number=8
XX
SQ   Sequence 3090 BP; 598 A; 878 C; 949 G; 665 T; 0 other;
     atggccgtca tggcgccccg aaccctcctc ctgctactct tgggggccct ggccctgacc        60
     cagacctggg cgggtgagtg cggggtcgtg gggaaaccgc ctctgcgggg agaagcaagg       120
     ggcccgcccg gcgggggcgc aggacccggg tagccgcgcc gggaggaggg tcgggcggat       180
     ctcagccact cctcgccccc aggctcccac tccatgaggt atttcaccac atccgtgtcc       240
     cggcccggcc gcggggagcc ccgcttcatc gccgtgggct acgtggacga cacgcagttc       300
     gtgcggttcg acagcgacgc cgcgagccag aggatggagc cgcgggcgcc gtggatagag       360
     caggagaggc ctgagtattg ggaccaggag acacggaatg tgaaggccca ctcacagatt       420
     gaccgagtgg acctggggac cctgcgcggc tactacaacc agagcgaggc cggtgagtga       480
     ccccagcccg gggcgcaggt cacgacctct catcccccac ggacgggcca ggtcacccac       540
     agtctccggg tccgagatcc accccgaagc cgcgggaccc cgagaccctt gccccgggag       600
     aggcccaggc gcctttaccc ggtttcattt tcagtttagg ccaaaaatcc ccccgggttg       660
     gtcggggccg gacggggctc gggggactgg gctgaccgtg gggtcggggc caggttctca       720
     caccatccag atgatgtatg gctgcgacgt ggggtcggac gggcgcttcc tccgcgggta       780
     ccagcaggac gcctacgacg gcaaggatta catcgccttg aacgaggacc tgcgctcttg       840
     gaccgcggcg gacatggcgg ctcagatcac ccagcgcaag tgggaggcgg cccgtgtggc       900
     ggagcagttg agagcctacc tggagggcac gtgcgtggag tggctccgca gatacctgga       960
     gaacgggaag gagacgctgc agcgcacggg taccaggggc cacggggcgc ctccctgatc      1020
     gcctgtagat ctcccgggct ggcctcccac aaggagggga gacaattggg accaacacta      1080
     gaatatcacc ctccctctgg tcctgaggga gaggaatcct cctgggtttc cagatcctgt      1140
     accagagagt gactctgagg ttccgccctg ctctgtgaca caattaaggg ataaaatctc      1200
     tgaaggaatg acgggaagac gatccctcga atactgatga gtggttccct ttgacacaca      1260
     ccggcagcag ccttgggccc gtgacttttc ctctcaggcc ttgttctctg cttcacactc      1320
     aatgtgtgtg ggggtctgag tccagcactt ctgagtccct cagcctccac tcaggtcagg      1380
     accagaagtc gctgttccct cttcagggac tagaattttc cacggaatag gagattatcc      1440
     caggtgcctg tgtccaggct ggtgtctggg ttctgtgctc ccttccccat cccaggtgtc      1500
     ctgtccattc tcaagatagc cacatgtgtg ctggaggagt gtcccattac agatgcaaaa      1560
     tgcctgaatg ttctgactct tcctgacaga ccccccccaa gacgcatatg actcaccacg      1620
     ctgtctctga ccatgaggcc accctgaggt gctgggccct gagcttctac cctgcggaga      1680
     tcacactgac ctggcagcgg gatggggagg accagaccca ggacacggag ctcgtggaga      1740
     ccaggcctgc aggggatgga accttccaga agtgggcgtc tgtggtggtg ccttctggac      1800
     aggagcagag atacacctgc catgtgcagc atgagggtct ccccaagccc ctcaccctga      1860
     gatggggtaa ggagggagat gggggtgtca tgtcttttag ggaaagcagg agcctctctg      1920
     acctttagca gggtcagggc ccctcacctt cccctctttt cccagagccg tcttcccagc      1980
     ccaccatccc catcgtgggc atcattgctg gcctagttct ctttggagct gtgttcgctg      2040
     gagctgtggt cgctgctgtg aggtggagga ggaagagctc aggtggggtg aaggggtgaa      2100
     gggtgggtct gagatttctt gtctcactga gggttccaag acccaggtag aagtgtgccc      2160
     tgcctcgtta ctgggaagca ccatccacaa ttatgggcct acccagcctg ggccctgtgt      2220
     gccagcactt actcttttgt aaagcacctg ttaaaatgaa ggacagattt atcaccttga      2280
     ttatggcggt gatgggacct gatcccagca gtcacaagtc acaggggaag gtccctgagg      2340
     accttcagga gggcggttgg tccaggaccc acacctgctt tcttcatgtt tcctgatccc      2400
     gccctgggtc tgcagtcaca catttctgga aacttctctg aggtccaaga cttggaggtt      2460
     cctctaggac cttaaggccc tggctccttt ctggtatctc acaggacatt ttcttcccac      2520
     agatagaaaa ggagggagct actctcaggc tgcaagtaag tatgaaggag gatgatccaa      2580
     gaaatcactg ggatattgtg tttgggagcc cgtgggggag ctcacccacc ccacaattcc      2640
     tcctctagcc acatcttctg tgggatctga ccaggttctg tttttgtcct accccaggca      2700
     gtgacagtgc ccagggctct gatatgtctc tcacagcttg taaaggtgag agcctggagg      2760
     gcctgatgtg tgttgggtgt tgggcggaac agtggacgca gctgtgctat ggggtttctt      2820
     tgcattggat gtattgagca tgcgatgggc tgtttaaagt gtgactcctc actgtgacag      2880
     atacgaattt gttcatgaat atttttttct atagtgtgag acagctgcct tgtgtgggac      2940
     tgagaggcaa gatttgttcc tgcccttccc tttgtgactt gaagtaccct gactttgttt      3000
     ctgcaaaggc acctgcatgt gtctgtgttc ttgtaggcat aatgtgagga ggtggggaga      3060
     ccaccccacc cccatgtcca ccatgaccct                                       3090
//


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