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EBI Dbfetch

ID   DQ351214; SV 1; linear; genomic DNA; STD; HUM; 1924 BP.
XX
AC   DQ351214;
XX
DT   29-JAN-2006 (Rel. 86, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 4)
XX
DE   Homo sapiens nonfunctional MHC class I antigen (HLA-B) gene, HLA-B*3940N
DE   allele, exons 1 through 5.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-1924
RA   Eller S.R., Chesterton K.A., Iglehart B.S., Leffell M.S.;
RT   "Identification of a Novel Allele B*3940N";
RL   Unpublished.
XX
RN   [2]
RP   1-1924
RA   Eller S.R., Chesterton K.A., Iglehart B.S., Leffell M.S.;
RT   ;
RL   Submitted (03-JAN-2006) to the INSDC.
RL   Medicine, Johns Hopkins University, 2041 E. Monument St, Baltimore, MD
RL   21205, USA
XX
DR   MD5; fd0ca7b5a653874033c7113ef34c024b.
DR   IMGT/HLA; B*39:40:01N; HLA02436.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1924
FT                   /organism="Homo sapiens"
FT                   /chromosome="6"
FT                   /map="6p21.3"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:9606"
FT   gene            <1..>1924
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*3940N"
FT                   /note="nonfunctional MHC class I antigen due to point
FT                   mutation"
FT   mRNA            join(<1..27,156..425,672..947,1520..1795,1889..>1924)
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*3940N"
FT                   /product="nonfunctional MHC class I antigen"
FT   exon            <1..27
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*3940N"
FT                   /number=1
FT   exon            156..425
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*3940N"
FT                   /number=2
FT   exon            672..947
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*3940N"
FT                   /number=3
FT   variation       892
FT                   /gene="HLA-B"
FT                   /note="point mutation results in a premature stop codon"
FT   exon            1520..1795
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*3940N"
FT                   /number=4
FT   exon            1889..>1924
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*3940N"
FT                   /number=5
XX
SQ   Sequence 1924 BP; 373 A; 600 C; 619 G; 332 T; 0 other;
     ccctggccct gaccgagacc tgggccggtg agtgcgggtc gggagggaaa tggcctctgc        60
     cgggaggagc gaggggaccg caggcggggg cgcaggacct gaggagccgc gccgggagga       120
     gggtcgggcg ggtctcagcc cctcctcgcc cccaggctcc cactccatga ggtatttcta       180
     cacctccgtg tcccggcccg gccgcgggga gccccgcttc atctcagtgg gctacgtgga       240
     cgacacgcag ttcgtgaggt tcgacagcga cgccgcgagt ccgagagagg agccgcgggc       300
     gccgtggata gagcaggagg ggccggaata ttgggaccgg aacacacaga tctgcaagac       360
     caacacacag actgaccgag agagcctgcg gaacctgcgc ggctactaca accagagcga       420
     ggccggtgag tgaccccggc ccggggcgca ggtcacgact ccccatcccc cacgtacggc       480
     ccgggtcgcc ccgagtctcc gggtccgaga tccgcctccc tgaggccgcg ggacccgccc       540
     agaccctcga ccggcgagag ccccaggcgc gtttacccgg tttcattttc agttgaggcc       600
     aaaatccccg cgggttggtc ggggcggggc ggggctcggg gggacggggc tgaccgcggg       660
     gccggggcca gggtctcaca ccctccagag gatgtacggc tgcgacgtgg ggccggacgg       720
     gcgcctcctc cgcgggcata accagttcgc ctacgacggc aaggattaca tcgccctgaa       780
     cgaggacctg agctcctgga ccgcggcgga caccgcggct cagatcaccc agcgcaagtg       840
     ggaggcggcc cgtgtggcgg agcagctgag aacctacctg gagggcacgt gagtggagtg       900
     gctccgcaga tacctggaga acgggaagga gacgctgcag cgcgcgggta ccaggggcag       960
     tggggagcct tccccatctc ctataggtcg ccggggatgg cctccaacga gaagaagagg      1020
     aaaatgggat cagcgctaga atgtcgccct cccttgaatg gagaatggca tgagttttcc      1080
     tgagtttcct ctgagggccc cctcttctct ctaggacaat taagggatga cgtctctgag      1140
     gaaatggagg ggaagacagt ccctagaata ctgatcaggg gtcccctttg acccctgcag      1200
     cagccttggg aaccatgact tttcctctca ggccttgttc tctgcctcac actcagtgtg      1260
     tttggggctc tgattccagc acttctgagt cactttacct ccactcagat caggagcaga      1320
     agtctctgtt ccccgctcag agactcgaac tttccaatga atagattatc ccaggtgcct      1380
     gcgtccaggc tggtgtctgg gttctgtgcc ccttccccac cccaggtgtc ctgtccattc      1440
     tcaggctggt cacatgggtg gtcctagggt gtcccatgag agatgcaaag cgcctgaatt      1500
     ttctgactct tcccatcaga ccccccaaag acacatgtga cccaccaccc catctctgac      1560
     catgaggcca ccctgaggtg ctgggccctg ggcttctacc ctgcggagat cacactgacc      1620
     tggcagcggg atggcgagga ccaaactcag gacaccgagc ttgtggagac cagaccagca      1680
     ggagacagaa ccttccagaa gtgggcagct gtggtggtgc cttctggaga agagcagaga      1740
     tacacatgcc atgtacagca tgaggggctg ccgaagcccc tcaccctgag atggggtaag      1800
     gagggggatg aggggtcata tctcttctca gggaaagcag gagcccttca gcagggtcag      1860
     ggcccctcat cttcccctcc tttcccagag ccatcttccc agtccaccgt ccccatcgtg      1920
     ggca                                                                   1924
//


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