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EBI Dbfetch

ID   AY645742; SV 1; linear; genomic DNA; STD; HUM; 6968 BP.
XX
AC   AY645742;
XX
DT   19-JUL-2004 (Rel. 80, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 4)
XX
DE   Homo sapiens isolate Afr-Am022 MHC class Ib antigen (HLA-F) gene,
DE   HLA-F*010101 allele, complete cds.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-6968
RX   DOI; 10.1007/s00251-005-0076-z.
RX   PUBMED; 16570139.
RA   Pyo C.W., Williams L.M., Moore Y., Hyodo H., Li S.S., Zhao L.P.,
RA   Sageshima N., Ishitani A., Geraghty D.E.;
RT   "HLA-E, HLA-F, and HLA-G polymorphism: genomic sequence defines haplotype
RT   structure and variation spanning the nonclassical class I genes";
RL   Immunogenetics 58(4):241-251(2006).
XX
RN   [2]
RP   1-6968
RA   Pyo C.-W., Ishitani A., Moore Y.F., Geraghty D.E.;
RT   ;
RL   Submitted (04-JUN-2004) to the INSDC.
RL   Clinical Division, Fred Hutchinson Cancer Research Center, 1100 Fairview
RL   Ave. N., D4-100, Seattle, WA 98109-1024, USA
XX
DR   MD5; 7893088e02f630a277d1d191f219e3e9.
DR   Ensembl-Gn; ENSG00000137403; homo_sapiens.
DR   Ensembl-Gn; ENSG00000204642; homo_sapiens.
DR   Ensembl-Gn; ENSG00000206509; homo_sapiens.
DR   Ensembl-Gn; ENSG00000229698; homo_sapiens.
DR   Ensembl-Gn; ENSG00000235220; homo_sapiens.
DR   Ensembl-Gn; ENSG00000237508; homo_sapiens.
DR   Ensembl-Tr; ENST00000259951; homo_sapiens.
DR   Ensembl-Tr; ENST00000334668; homo_sapiens.
DR   Ensembl-Tr; ENST00000359076; homo_sapiens.
DR   Ensembl-Tr; ENST00000376848; homo_sapiens.
DR   Ensembl-Tr; ENST00000376861; homo_sapiens.
DR   Ensembl-Tr; ENST00000383515; homo_sapiens.
DR   Ensembl-Tr; ENST00000420067; homo_sapiens.
DR   Ensembl-Tr; ENST00000434407; homo_sapiens.
DR   Ensembl-Tr; ENST00000440590; homo_sapiens.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..6968
FT                   /organism="Homo sapiens"
FT                   /chromosome="6"
FT                   /map="6p21.3"
FT                   /isolate="Afr-Am022"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:9606"
FT   gap             973..1340
FT                   /estimated_length=368
FT   gene            <1919..>4861
FT                   /gene="HLA-F"
FT                   /allele="HLA-F*010101"
FT   mRNA            join(<1919..1982,2113..2382,2628..2903,3486..3761,
FT                   3901..4017,4465..4497,4857..>4861)
FT                   /gene="HLA-F"
FT                   /allele="HLA-F*010101"
FT                   /product="MHC class Ib antigen"
FT   CDS             join(1919..1982,2113..2382,2628..2903,3486..3761,
FT                   3901..4017,4465..4497,4857..4861)
FT                   /codon_start=1
FT                   /gene="HLA-F"
FT                   /allele="HLA-F*010101"
FT                   /product="MHC class Ib antigen"
FT                   /db_xref="GOA:P30511"
FT                   /db_xref="HGNC:HGNC:4963"
FT                   /db_xref="IMGT/HLA:F*01:01:01:03"
FT                   /db_xref="InterPro:IPR001039"
FT                   /db_xref="InterPro:IPR003006"
FT                   /db_xref="InterPro:IPR003597"
FT                   /db_xref="InterPro:IPR007110"
FT                   /db_xref="InterPro:IPR011161"
FT                   /db_xref="InterPro:IPR011162"
FT                   /db_xref="InterPro:IPR013783"
FT                   /db_xref="InterPro:IPR027648"
FT                   /db_xref="UniProtKB/Swiss-Prot:P30511"
FT                   /protein_id="AAT73225.1"
FT                   /translation="MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIA
FT                   VEYVDDTQFLRFDSDAAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLR
FT                   RYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQI
FT                   TQRFYEAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATL
FT                   RCWALGFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCH
FT                   VQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGS
FT                   YSQAAV"
XX
SQ   Sequence 6968 BP; 1547 A; 1665 C; 1784 G; 1604 T; 368 other;
     ggtaatggaa cagtgctaga gccactattc aggagtgaca gagtggtggg gactaaggga        60
     agaggagggc ctgagggatg agagggacgg agggaagggc tggagaagca ggaggtgagg       120
     agaaggagca gagggacaga atttgaaagc agcagaattc ttagctttaa acacattgtt       180
     ttataaattt ttaatacatc catctacaga gcctagcagg gtgttccttg catttggcct       240
     ttaacacctt atgtgggact gcctaaaaat taattgcttt ttctgctttt tttcaggttt       300
     aaaaaaatac taagtgttcc aataaaacat gcacaccact tagatgcgga tacttcctaa       360
     aaacaggaag tgcatgagca ctggtgaggg gcattgtgac tgcgttgaac acttgcaact       420
     ttgaggtgaa tgaatgtatt ggctcctggt tgcaatatac aatcacacgt tgtgctactt       480
     tgtattgtca ggagatgtcc tggactccca cagaaactca gggctatgga atgaaggtaa       540
     ttttagaata caacaagagt cacagataca tagtctggga aagcaaaact taggagctct       600
     gagagttgta caactgtaat gcatttagac acatttatat atcaaggggc caaagtaaca       660
     gtttttacac ataagattcc tgattggtcg ggcgcggtgg ctcatgcctg taattgcagc       720
     actttgggag gccgaggcgg gaggatcacg aggtcaggag atcgagacca tcctggctaa       780
     cacggtgaaa cccgtctcta caaaaaaatt agccgggcgt ggtggcgggc atctgtagtc       840
     tcagctactc gggaggctga agcagaagaa tggcgtgaac ccgggacgca gagcttgcag       900
     tgagccgaga tcgcgccact gcactccagc ctgggcggca gagagagact ccgtctcaaa       960
     aaaaaaaaaa aannnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn      1020
     nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn      1080
     nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn      1140
     nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn      1200
     nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn      1260
     nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn      1320
     nnnnnnnnnn nnnnnnnnnn gaagaagagg aagaagaaga aactgtctct agaccttcat      1380
     tctcaggaca agttcattgt ctggcaccaa gctccttggg gtgaattttc ttccaaaaga      1440
     gtccggggag tccaggtatg gaatgggagg cagaaagttc aatcaaggga ctgggatttc      1500
     ggaatgaata atgaagggag atggactggg tccatgccga aggtttctcc ctggtttctc      1560
     agcccccggg cgaagactca gggagacatt gagacacacc ctgcacagga gggggagggg      1620
     gagggggagg gcaaagtccc agggccccag gagtggctct caagggctca ggccccgagg      1680
     cggtgtctgg ggttggaagg ctcagtattg agaattcccc atctccccag agtttctctt      1740
     tctctcccaa cccgtgtcag gtccttcatc ctggatactc ataacgcggc cccatttctc      1800
     actcccattg ggcgtcgcgt ttctagagaa gccaatcagt gtcgccgcag ttcccaggtt      1860
     ctaaagtccc acgcaccccg cgggactcat atttttccca gacgcggagg ttggggtcat      1920
     ggcgccccga agcctcctcc tgctgctctc aggggccctg gccctgaccg atacttgggc      1980
     gggtgagtgc ggggtccaga gagaaacggc ctctgtgggg aggagtgagg ggcccgcccg      2040
     gtgggggcgc aggactcagg gagccgcgcc cggaggaggg tctggcgggt ctcagcccct      2100
     cctcgccccc aggctcccac tccttgaggt atttcagcac cgctgtgtcg cggcccggcc      2160
     gcggggagcc ccgctacatc gccgtggagt acgtagacga cacgcaattc ctgcggttcg      2220
     acagcgacgc cgcgattccg aggatggagc cgcgggagcc gtgggtggag caagaggggc      2280
     cgcagtattg ggagtggacc acagggtacg ccaaggccaa cgcacagact gaccgagtgg      2340
     ccctgaggaa cctgctccgc cgctacaacc agagcgaggc tggtgagtga acccggccgg      2400
     gggcgcaggt cacgaccacc ccccatccgc cacggaccgc ccgggtcccc ccgagtctcc      2460
     ggatccgaaa tctaccccga ggcagcggga cccgcccaga ccctccaccc gggagagtcc      2520
     caggcgcctt taccgaggtt cattttcagt ttaggccaaa atccccgcgg gttgggcggg      2580
     gagggggcgg ggctagctgg gcggggctga ctgcggggac cggctagggt ctcacaccct      2640
     ccagggaatg aatggctgcg acatggggcc cgacggacgc ctcctccgcg ggtatcacca      2700
     gcacgcgtac gacggcaagg attacatctc cctgaacgag gacctgcgct cctggaccgc      2760
     ggcggacacc gtggctcaga tcacccagcg cttctatgag gcagaggaat atgcagagga      2820
     gttcaggacc tacctggagg gcgagtgcct ggagttgctc cgcagatact tggagaatgg      2880
     gaaggagacg ctacagcgcg caggtaccag gggccatggg cgccttccct atctcctgta      2940
     gatctcttgg gatggcctcg cacaaggttg ggaggaaagt gggcccaatg ctaggatatc      3000
     gccctccctc tagtcctgag taggaagaat cttcctggct ttcgagatcc ggtaccagag      3060
     agtgactgtg agagtccgcc ctgctctctg ggacaattaa gggatgaaat ctctgaggga      3120
     atggagggaa gacagtccct ggaataccga tccgcggtcc cctttgagcc ctccaacagc      3180
     cttgggcccc gtgacttttc tctcaagttt tgttctctgc ctcacactca atgtgtttgg      3240
     ggctctgatt ccagtccctc ggcctccact taggtcaggg ccagaagtcc ctgctcccca      3300
     ctcagagact cgaactttcc aaggaatagg agattttccc aggtgtctgt gtccaggctg      3360
     gtgtctgggt tctgtgctcc cttccccacc ccaggtgtcc tgtccattct caggttggtc      3420
     acatgggtgc tgctggggtt tcccatgagg agtgcaaagt gcctgaattt tctgactctt      3480
     ctcagatcct ccaaaggcac acgttgccca ccaccccatc tctgaccatg aggccaccct      3540
     gaggtgctgg gccctgggct tctaccctgc ggagatcacg ctgacctggc agcgggatgg      3600
     ggaggaacag acccaggaca cagagcttgt ggagaccagg cctgcagggg atggaacctt      3660
     ccagaagtgg gccgctgtgg tggtgccttc tggagaggaa cagagataca catgccatgt      3720
     gcagcacgag gggctgcccc agcccctcat cctgagatgg ggtaaggagg gagatgggta      3780
     aagaggggaa cgaggggtca tgtcttttct cagggaaagc aggagccctt ctggagctct      3840
     tcagcagggt cagggctgag cctggagatc agggcccctc accttccctt cctttcccag      3900
     agcagtctcc ccagcccacc atccccatcg tgggcatcgt tgctggcctt gttgtccttg      3960
     gagctgtggt cactggagct gtggtcgctg ctgtgatgtg gaggaagaag agctcaggta      4020
     ggaaggggtg aggagtggag tctgagtttt cttgtcccac tgggggttgc aagccccaag      4080
     tagaagtgtg ccctgcctca ttactgggaa gcaccatcca cactcatggg tctacccagc      4140
     ctgggccctg tgtgccagca cctactcatt tgtaaagctc ctgtgaaaat gaaggacaga      4200
     ttcttcactt cgatgattat ggtggtgatg ggacctgatc ccagcagtca caaatcacag      4260
     gggaaggtcc ctgctgatga cagacctcag gagggcagtt ggtccaggac ccacatctgc      4320
     tttcttcata tttcttgatc ctgccctgga tctacagtta cacttttctg gaaacttctc      4380
     tgggatcaaa gactaggggt ttgctctagg accttatggc cctgcctcct ttctggcctc      4440
     tcacaggaca ttttcttccc atagatagaa acagagggag ctactctcag gctgcaggta      4500
     agatgaagga ggctgatccc tgagattgtt gggatattgt ggtcaggagc ctatgaggga      4560
     gctcacccac cccacagttc ctctagccac atctgtgggc tctgaccagg tcctgttttt      4620
     gttctacccc aatcactgac agtgcccagg gctctggggt gtctctcaca gctaataaag      4680
     gtgacactcc agggcagggg ccctgatgtg agtggggtgt tgggggggaa cagaggggac      4740
     tcagctgtgc tattgggttt ctttgacttg gatgtcttga gcatgaaatg ggctatttag      4800
     agtgttacct ctcactgtga ctgatacgaa tttgttcatg aatattttct ctatagtgtg      4860
     agacagcttc cttgtgtggg actgagaagc aagatatcaa tgtagcagaa ttgcacttgt      4920
     gcctcacgaa catacataaa ttttaaaaat aaagaataaa aatatatctt tttatagata      4980
     caggtagata tgtttttata gcatgcacgt aaatgtgtgt gtgtgtgtgt gtgaagagaa      5040
     agagtgaata gagagattaa gattctttta atggtgaaaa gatatacata tatttggaat      5100
     tagccagctt gactcagttt aggtgatccc aattttggtg gcaacaacca aagcatcgta      5160
     gtcaggagcc agtcgaacat atgccttcct ctctccatca gactgaatca gagtgttgac      5220
     tttggccaca tcaatgtcac aaacttcttc acagcctgtt tgatctggtg cttgttggct      5280
     ttaacatcca cagtgaacac aagtaggctg ttgttttcta tcttcttcac agcctactca      5340
     gtggtcagcg gaaacttgat gataacatgg tggtcaagct tatttctcct gggggtgctc      5400
     ttccaaggat atttgggctg cctccggagt cacagtgtct tgggccgccg gaaggtgggt      5460
     gacatgtgga tcttgttttt tttgtggctg tggacatctt tcaacactgc cttcttggcc      5520
     ttgcaaagcc ttcgctttgg cttcggcttt aggaggggca ggagcttcct tcttcgttct      5580
     tggcaccatc ttatgaaaag ggtccagatt aagatttttg actgagtcat tctaaagtaa      5640
     gttgcaagac ccatgatact agaccactaa atacttcatc acacacctcc taagaataag      5700
     aaccaacatt atcacaccaa agaaaataaa taattccata atattattta aagtcctttt      5760
     atgttcaaat atctccactt ctttcagtac atttttgtac ctatttttta tagcttgttt      5820
     tcttaaaatg tccactcgtt gcctttggtt atgtttcttt aattacctac aatctataac      5880
     aatcaaccca tcttttttct tttagaatgg cattacctgt ttcagagatg aggccaaata      5940
     cctgtggaat cttctccaca ctgaatttat catattagtt cccctgatgc ctttaacttt      6000
     tttcctctaa ctgctatgcc tcctaaggac ctatgtagct ctgggttaaa catttggcag      6060
     caatgtttac aggaggagct gtgaccgcac attcatcaca tcaggaggca cacaaagcct      6120
     agggttacca ggactcttac tgaccccata cagccaaatt tatcctgact tcccagagat      6180
     gcagaaccat gggctgggtg tttagtgggt atgagtgtga tattctggca ataggaggtt      6240
     ctgccactct ccccattcct cacgagcttt agttccccat accctgaggt tctgagctcc      6300
     agaccttcaa ccatcaggcc aggcccctcc agacctagac tcccttcctg tcttctccag      6360
     ccccactctg ctttgtatct acttctggat cactttccct ctacaggccc agctcctgag      6420
     tgtctctacc tctcaaacaa gtattctcat ccaggagcaa ttttcccacc agaggacatt      6480
     agctatgtct ggaaaaatgt tttgttgcca tgactggagt gaggaggagg tgctaccagc      6540
     atcttgtggg gaatgaccag ggatgctgaa catcctgcag tgcacaagtc agcccaatca      6600
     cccacataac agataattat ccagccccaa taccaagatt gccaagggta ggaggcctgc      6660
     caggactttc tctcccttga gtacaagctt ccttgaactg agggacaccc tgaaggaaaa      6720
     gtgtggtccc accccagtca tctctccctt ccctggagct ccatctgtat gcctgtagtg      6780
     cttaggcctg taacctgggg tccaggaacc caccttccca tgagactgca tgcagaagtg      6840
     atgatatgtg cacacatgac ttcattacag ggcattggat attgatattc atcaggtcag      6900
     ctggggccca agacactact cttctgccaa caggccgcaa tcctctgcat tagagagagg      6960
     gtaaagat                                                               6968
//


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