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EBI Dbfetch

ID   AY603357; SV 1; linear; genomic DNA; STD; HUM; 7012 BP.
XX
AC   AY603357;
XX
DT   11-MAR-2005 (Rel. 83, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 3)
XX
DE   Homo sapiens MHC class I chain-related protein A (MICA) gene, partial cds.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-7012
RA   Kaur G., Shiina T., Hashimoto N., Kumar N., Inoko H., Mehra N.K.;
RT   "MIC-A sequence in AH8.2";
RL   Unpublished.
XX
RN   [2]
RP   1-7012
RA   Kaur G., Shiina T., Hashimoto N., Kumar N., Inoko H., Mehra N.K.;
RT   ;
RL   Submitted (20-APR-2004) to the INSDC.
RL   Transplant Immunology & Immunogenetics, All India Institute of Medical
RL   Sciences, Ansari Nagar, New Delhi, New Delhi 110029, India
XX
DR   MD5; c4863390f2dcbfe0274ea8099c186ce0.
DR   Ensembl-Gn; ENSG00000183214; homo_sapiens.
DR   Ensembl-Gn; ENSG00000235233; homo_sapiens.
DR   Ensembl-Tr; ENST00000400325; homo_sapiens.
DR   Ensembl-Tr; ENST00000418465; homo_sapiens.
DR   Ensembl-Tr; ENST00000547609; homo_sapiens.
DR   IMGT/LIGM; AY603357.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..7012
FT                   /organism="Homo sapiens"
FT                   /chromosome="6"
FT                   /map="6p21.3"
FT                   /mol_type="genomic DNA"
FT                   /haplotype="ancestral haplotype 8.2"
FT                   /db_xref="taxon:9606"
FT   gene            <551..>2437
FT                   /gene="MICA"
FT   mRNA            join(<551..803,1078..1365,1953..2231,2331..>2437)
FT                   /gene="MICA"
FT                   /product="MHC class I chain-related protein A"
FT   CDS             join(<551..803,1078..1365,1953..2231,2331..2437)
FT                   /codon_start=1
FT                   /gene="MICA"
FT                   /product="MHC class I chain-related protein A"
FT                   /db_xref="GOA:Q29983"
FT                   /db_xref="HGNC:HGNC:7090"
FT                   /db_xref="IMGT/HLA:MICA*008:01:01"
FT                   /db_xref="InterPro:IPR001039"
FT                   /db_xref="InterPro:IPR003597"
FT                   /db_xref="InterPro:IPR007110"
FT                   /db_xref="InterPro:IPR011161"
FT                   /db_xref="InterPro:IPR011162"
FT                   /db_xref="InterPro:IPR013783"
FT                   /db_xref="PDB:1B3J"
FT                   /db_xref="PDB:1HYR"
FT                   /db_xref="UniProtKB/Swiss-Prot:Q29983"
FT                   /protein_id="AAV39504.1"
FT                   /translation="PHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYDRQKCRAKPQ
FT                   GQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNSTR
FT                   SSQHFYYDGELFLSQNLETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADC
FT                   LQELRRYLESGVVLRRTVPPMVNVTRSEASEGNITVTCRASSFYPRNIILTWRQDGVSL
FT                   SHDTQQWGDVLPDGNGTYQTWVATRICRGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQS
FT                   HWQTFHVSAVAAGCCYFCYYYFLCPLL"
XX
SQ   Sequence 7012 BP; 1558 A; 1820 C; 1963 G; 1671 T; 0 other;
     actgacccca ctataaactt ctctggggct acaaccttcc taccctttgt gcctcatgac        60
     caccccctcc cttgtccccg ccatgcccat gatgagtctc ttctcgaggc agctcccctt       120
     gcctccatct caccctcagc ctatgcacca cagccacact ggacatgggt ccctctgagc       180
     ctgagtccct tcccattccc accatctcct ctggcaagac cttccttcca ccaccttcat       240
     gctcctccct tgcccctgca gggcagcctc tccccttggc ccctattccc ttagggggct       300
     tgtggccacc cagtccttgc acctggccta caagtttgcc atcttcattc ccccttcttc       360
     tgttcatcag ccccctcctc tatcctccca ccctcacagt tttctttgta tatgaaatcc       420
     tcgttcttgt ccctttgccc gtgtgcattt cctgccccag gaaggttggg acagcagacc       480
     tgtgtgttaa acatcaatgt gaagttactt ccaggaagaa gtttcacctg tgatttcctc       540
     ttccccagag ccccacagtc ttcgttataa cctcacggtg ctgtcctggg atggatctgt       600
     gcagtcaggg tttcttgctg aggtacatct ggatggtcag cccttcctgc gctatgacag       660
     gcagaaatgc agggcaaagc cccagggaca gtgggcagaa gatgtcctgg gaaataagac       720
     atgggacaga gagaccaggg acttgacagg gaacggaaag gacctcagga tgaccctggc       780
     tcatatcaag gaccagaaag aaggtgagag tcggcagggg caagagtgac tggagaggcc       840
     ttttccagaa aagttagggg cagagagcag ggacctgtct cttcccactg gatctggctc       900
     aggctggggg tgaggaatgg gggtcagtgg aactcagcag ggaggtgagc cggcactcag       960
     cccacacagg gaggcatgga ggagggccag ggaggcatac cccctgggct gagttcctca      1020
     cttgggtgga aaggtgatgg gttcgggaat ggagaagtca ctgctgggtg ggggcaggct      1080
     tgcattccct ccaggagatt agggtctgtg agatccatga agacaacagc accaggagct      1140
     cccagcattt ctactacgat ggggagctct tcctctccca aaacctggag actgaggaat      1200
     ggacagtgcc ccagtcctcc agagctcaga ccttggccat gaacgtcagg aatttcttga      1260
     aggaagatgc catgaagacc aagacacact atcacgctat gcatgcagac tgcctgcagg      1320
     aactacggcg atatctagaa tccggcgtag tcctgaggag aacaggtacc gacgctggcc      1380
     aggggctctc ctctccctcc aattctgcta gagttgcctc acctcccaga tgtgtccagg      1440
     gaaaccctcc ctgtgctatg gatgaaggca tttcctgttg gcacatcgtg tcctgatttt      1500
     cctctattgt tagagccact ggataaagac agagggtcag ggactggacc atccagtgtt      1560
     gtaatcaggg caagtagagg accctccgac agaatcctga gcctgtggtg ggtgtcaggc      1620
     aggagaggaa gccttcaggg ccagggctgc cccctctgcc tcccagcctg cccatcctgg      1680
     agagttccct cctggcccca caacccagga gtccacccct gacatccccc tcctcagcat      1740
     caatgtgggg atcccagagc ctgaggccac agtcccaagg cccatcctcc tgccagcctg      1800
     gaagaactgg gccccagagt gaggacagac ttgcaggtca ggggtcccgg agggcttcag      1860
     ccagagtgag aacagtgaag agaaacagcc ctgttcctct cccctcctta gaggggagca      1920
     gggcttcact ggctctgccc tttcttctcc agtgcccccc atggtgaatg tcacccgcag      1980
     cgaggcctca gagggcaaca tcaccgtgac atgcagggct tccagcttct atccccggaa      2040
     tatcatactg acctggcgtc aggatggggt atctttgagc cacgacaccc agcagtgggg      2100
     ggatgtcctg cctgatggga atggaaccta ccagacctgg gtggccacca ggatttgccg      2160
     aggagaggag cagaggttca cctgctacat ggaacacagc gggaatcaca gcactcaccc      2220
     tgtgccctct ggtgagccta gggtgaccct ggagagggtc aggccagggt agggacagca      2280
     gggatggctg tggctctctg cccagtgtat aacaagtccc tttttttcag ggaaagtgct      2340
     ggtgcttcag agtcattggc agacattcca tgtttctgct gttgctgctg gctgctgcta      2400
     tttttgttat tattattttc tatgtccgtt gttgtaagaa gaaaacatca gctgcagagg      2460
     gtccaggtga gaaaagcggg cagtttctgg agatggtaag gcccctgtct gggcagtagg      2520
     gtcccctcat tgctcctgca aagataggca tgttggtgac aaggcttccg taacagggga      2580
     tgaaagttgg ggaatttggg aagggaatgg gggcagcatc tccatctaca cccataagtg      2640
     ctgcccaagc aagggtcaaa cgcccagctg tggcatcctc ctgctgcagg tgaggagtgg      2700
     gcagcaggga gggctgcggc gcctgctctg tccccatccc ggtctctgtg tctcttgaac      2760
     tcactagggc gcatccaggt ggggtgagct gggaatcacg tgctgaatgc taagggcctg      2820
     gatgatcacg gcctcagagg gagcaaatag taaaggcagc tgtgatctgg ggagggccag      2880
     aaactggaga ggaatctgag gagaggcggt gcccctattc ccttcctctc tgcatccccc      2940
     tcccctgttt ctccagccat cggggcggac accgagaaaa agacctatga ggcccagcct      3000
     gggggccctg cctgtgtagc cctttggaga ccccttgtaa cagggagggt cctgagcaca      3060
     catggccatc tctgtccact ttgcagctcc ccatgcacct cctccaggag ctttcttggg      3120
     gttgtcgtgt cctctgcacc attcgaggcc ctactctttc caggttccca cggcctggcc      3180
     tccctgagtt tcttgcagat gacatggatg agtagataag cagatgtccc tgggccattt      3240
     gaggagtggg gcccagcccc tcatcagggc agctgtggtc cctgttttca tcctacctcc      3300
     gagtgttttc ttctccagtc cctgagggac acagtcctca gggcccatgt ttttggggat      3360
     ttaatctgtg ctctgtggcc tcaccttgcc ctccctgagc caatttccct ttctaaaggt      3420
     ggtcactgcc tggtaagttt ggagtaaggg acggtcagaa tcatttcccc tacagtcagg      3480
     ttgtttgatg ggggatgaaa agagacagca ggaagttttg tgtttctgca aagacagaag      3540
     cagttcaggc gacagtaaga ggctggggtg tccaggagga tgtgtctggc agtagggtcg      3600
     ctggtttctc atccttgaac ctaattgcac tgtcaatcgg cccctcaggc ctgagcagat      3660
     gggaaggttt gtcccctgcc ctgcagcaag agggccctgt ccaggaggca cccacaacag      3720
     gggcagtgca ggtctgtggt cactcctgct ctcacctgtg gcgtctcccg tagagggatt      3780
     gtcagttctg gttccctgtg ggcaggaatg gtttcctcat aggtcactgg agttttggcc      3840
     aggaaaagag tatgaagttc atgtgccagt ttctcaaaat tcctgctttc aatgttgatg      3900
     tccagtaaag atattcgtaa tttcagctct ataatcttaa taggatttcc tctaatattg      3960
     tgaagcatat tatatgaaac aggaacacaa atttctcaaa attcctgcga tgtccaataa      4020
     agattttcat aatttcagct ctgcaatctt aataggattt cctaatactg taaagcatat      4080
     taaatgaaac aggaactcaa atttggagcc ccctctccag gaggttctgt gtggagatgg      4140
     tggctgtggc agtggcagtt cccaggtgca gagggtgggc agaggcagcc tcaggctaag      4200
     gggtctcccc tactccacat ggagaaaatc ccttgtaggt tgcaagggca gtggccgggt      4260
     ggaatccctg ctagggacag agcaggaagg cctcgcagcc tcaccaagca gcagccctgg      4320
     ggtggagctg cgtttccagg gttaagcgga ccaggcagga gtagcggtta ctcaagagca      4380
     ggtcacaggc ttgggttgtg agggtcagga gaggccaggc ctcctcgagc aaggtggggg      4440
     tcccagggtc aggtcaggtg cagatcctgt ggcagccacg tctttccatg ctgggcctgc      4500
     tgggcccccc aggcttcctg atggggtccc cagttaggag ctgcctgctc agggctggga      4560
     ggggaggagc actgagctgc agatagaggg cagagcccac agtgggcagg gcctgccctg      4620
     gtgtgtaggt gcctctgcag gagaggaggg cctggggact gagagcaagg ctcagggcct      4680
     ctctttgggg aggcctctca ctgtaacagg actggtcagg cctgagagga gggcactggg      4740
     ttccctcttg ggtcttgtcc tttagtcttg gggccctttc cctccctgca cgatgagtgg      4800
     tgggcacagg gcacgggctg atgttgatgg agtgatggga gggaactggc aggggctggg      4860
     aaaagcaagg agggaggaag aaaaaagtgg gggcctcatc ttccctcaga gaaagggcaa      4920
     atctggtttt ggagcaactg aagagtgaaa agtccccagg gaataaacac aacactgcac      4980
     ccagtggagc atttacccat ttccctcttt tctccagagc tcgtgagcct gcaggtcctg      5040
     gatcaacacc cagttgggac gagtgaccac agggatgcca cacagctcgg atttcagcct      5100
     ctgatgtcag ctcttgggtc cactggctcc actgagggca cctagactct acagccaggc      5160
     ggctggaatt gaattccctg cctggatctc acaagcactt tccctcttgg tgcctcagtt      5220
     tcctgaccta tgaaacagag aaaataaaag cacttattta ttgttgttgg aggctgcaaa      5280
     atgttagtag atatgaggca tttgcagctg tgccatatta attggtgtca ttgtttttgt      5340
     tgttttcgta ttattatttt ttttttttaa gacagagtct caggccaggc acggtggctc      5400
     acgcctgtaa tcccaacact ttgggaggcc gaggcgggcg gatcacaagg tcaagagatc      5460
     gagaccatcc tgatcaacat ggtgaaaccc tgtctctact aaaaatacaa aaaattagct      5520
     gggcctggtg gcgtgtgcct gtagtcccag ctactcagga gctgaggcag gaaaatcact      5580
     tgaacctggg aggtggaggt tgcagtgagc tgagtatcac accactgcac tccagcctgg      5640
     cgacagagcg agactctgtc tcaaaaaaaa aaaaaaaaaa agacagagtc tcactctgtc      5700
     acccaggctg cagttcagtg acatgatctc agctcgttgc acctccgcct cccgggttca      5760
     agcacttctc ttgcctcagc ctcccgagta gctggggtta cagacatgca ccaccatacc      5820
     cggctaattt ttgcattttt catagagaca ggattttgcc atgttggcca ggctggtctc      5880
     aaactcctga cctcaggtga tctgcctgcc tcagcctccc aaagtgctgg gattacaagc      5940
     atgagccacc atacccggcc tattttatta cattttaatt tattttattt tattatatca      6000
     tccaccatgt ctggcctatt ttattatatt ttaagatatt ttaatatatt acgtgtgttg      6060
     taattggatt atcatcggtg agctttgtga gtgagtgtct tggagatgac tcctcctgac      6120
     cagcccagga ccagctttct tgtcaccttg aggtcccctc gccccatcac actcttacgc      6180
     attactctat gtctactgtt atgggtgtgt aattttatac catagatgtt tactctttaa      6240
     acagacactt ctagtctgtt ttatttcatg tgtctgggag cggataaagt gtgaggttca      6300
     gggagaaaga gaggtctgtc tcaatgcctt ggcacggcat gaagacaatc tcccctcctt      6360
     gtcccctttc cctgctagct cctgatgact gacagattca cagcagaaca gaaaggactg      6420
     ggaagggatg gaggtgggac atctggcact gaccttcagg ggctgaccct gtgggggaac      6480
     atctgccctg aagagttgga gccttcatgt gatgacacag agctgaagtg tgatattcgg      6540
     gaggggatag agagtgcttg gaggttttct gattttgaag aatcccagtc agtcaggttc      6600
     tggcgtaaag tgactgctgg ggaggtgtgg actgaatgaa tgaagaataa atgaaccagg      6660
     aaagtggaca tgcaagaggt gggttattcc tcaccctatt tcttgatgcc tcctgactgc      6720
     tggtgttggg gcacacagat gggtgatgca cttcttggtc aaggcaacct cagccccacc      6780
     cacgtaaggt ggtcatggca gagagtgtaa gggtgacacc tgtgaaaaag acccaaggca      6840
     gggatgggag cccttcttgc agcaggagtg gatgcaggac ctgcctggaa gcaagagaag      6900
     gacgagggac cctggctggg ccctgtttcc tcccactgcc tggttcacaa agcaaccagt      6960
     aagggagctg gagtagggaa ttcactcatg tgctacttac tgatccaatt ga              7012
//


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