Dbfetch
ID AY509614; SV 1; linear; genomic DNA; STD; HUM; 3059 BP. XX AC AY509614; XX DT 28-JAN-2004 (Rel. 78, Created) DT 17-JUN-2008 (Rel. 96, Last updated, Version 5) XX DE Homo sapiens MHC class I antigen precursor (HLA-Cw) gene, HLA-Cw*0508 DE allele, complete cds. XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-3059 RA Robbins F.-M., Adams S., Barracchini K., Gress R., Stroncek D.; RT "Identification of novel HLA class I alleles"; RL Unpublished. XX RN [2] RP 1-3059 RA Robbins F.-M., Adams S., Barracchini K., Gress R., Stroncek D.; RT ; RL Submitted (19-DEC-2003) to the INSDC. RL Transfusion Medicine, NIH, CC, 9000 Rockville Pike, Bethesda, MD 20892, USA XX DR MD5; 1560938f348bbf8027a77fe08ce4b46f. DR IMGT/HLA; HLA-C*05:08; HLA01843. XX FH Key Location/Qualifiers FH FT source 1..3059 FT /organism="Homo sapiens" FT /chromosome="6" FT /map="6p21" FT /isolate="#30393Sb" FT /mol_type="genomic DNA" FT /tissue_type="peripheral blood" FT /db_xref="taxon:9606" FT gene 1..>3059 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" FT mRNA join(1..198,329..598,845..1120,1708..1983,2105..2242, FT 2664..2696,2804..2851,3016..>3059) FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" FT /product="MHC class I antigen precursor" FT exon 1..198 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" FT /number=1 FT 5'UTR 1..125 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" FT CDS join(126..198,329..598,845..1120,1708..1983,2105..2242, FT 2664..2696,2804..2851,3016..3020) FT /codon_start=1 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" FT /product="MHC class I antigen precursor" FT /note="HLA Cw*05 variant; antigen presenting molecule" FT /db_xref="GOA:Q6R743" FT /db_xref="InterPro:IPR001039" FT /db_xref="InterPro:IPR003006" FT /db_xref="InterPro:IPR003597" FT /db_xref="InterPro:IPR007110" FT /db_xref="InterPro:IPR010579" FT /db_xref="InterPro:IPR011161" FT /db_xref="InterPro:IPR011162" FT /db_xref="InterPro:IPR013783" FT /db_xref="InterPro:IPR036179" FT /db_xref="InterPro:IPR037055" FT /db_xref="UniProtKB/TrEMBL:Q6R743" FT /protein_id="AAR99590.1" FT /translation="MRVMAPRTLILLLSGALALTETWACSHSMRYFYTAVSRPGRGEPR FT FIAVGYVDDTQFVQFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRVNLRK FT LRGYYNQSEAGSHTLQRMYGCDLGPDGRLLRGYNQFAYDGKDYIALNEDLRSWTAADKA FT AQITQRKWEAAREAEQWRAYLEGTCVEWLRRYLENGKKTLQRAEHPKTHVTHHPVSDHE FT ATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRY FT TCHVQHEGLPEPLTLRWGPSSQPTIPIVGIVAGLAVLAVLAVLGAVMAVVMCRRKSSGR FT EGVRSGKGGSCSQAASSNSAQGSDESLIACKA" FT sig_peptide 126..197 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" FT mat_peptide join(198,329..598,845..1120,1708..1983,2105..2242, FT 2664..2696,2804..2851,3016..3017) FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" FT /product="MHC class I antigen" FT /note="HLA Cw*05 variant; antigen presenting molecule" FT exon 329..598 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" FT /number=2 FT exon 845..1120 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" FT /number=3 FT exon 1708..1983 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" FT /number=4 FT exon 2105..2242 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" FT /number=5 FT exon 2664..2696 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" FT /number=6 FT exon 2804..2851 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" FT /number=7 FT exon 3016..>3059 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" FT /number=8 FT 3'UTR 3021..>3059 FT /gene="HLA-Cw" FT /allele="HLA-Cw*0508" XX SQ Sequence 3059 BP; 580 A; 888 C; 965 G; 626 T; 0 other; gacgcgtccc caattcccac tcccattggg tgtcgggttc tagagaagcc aatcagcgtc 60 tccgcagtcc cggttctaaa gtccccagtc acccacccgg actcggattc tccccagacg 120 ccgagatgcg ggtcatggcg ccccgaaccc tcatcctgct gctctcggga gccctggccc 180 tgaccgagac ctgggcctgt gagtgcgagg ttgggaggga aacggcctct gcggagagga 240 gcgaggggcc cgcccggcga gggcgcagga cccggggagc cgcgcaggga ggagggtcgg 300 gcgggtctca gcccctcctc gcccccaggc tcccactcca tgaggtattt ctacaccgcc 360 gtgtcccggc ccggccgcgg agagccccgc ttcatcgcag tgggctacgt ggacgacacg 420 cagttcgtgc agttcgacag cgacgccgcg agtccaagag gggagccgcg ggcgccgtgg 480 gtggagcagg aggggccgga gtattgggac cgggagacac agaagtacaa gcgccaggca 540 cagactgacc gagtgaacct gcggaaactg cgcggctact acaaccagag cgaggccggt 600 gagtgacccc ggcccggggc gcaggtcacg acccctcccc atcccccacg gacggcccgg 660 gtcgccccga gtctcccggt ctgagatcca ccccgaggct gcggaacccg cccagaccct 720 cgaccggaga gagccccagt cacctttacc cggtttcatt ttcagtttag gccaaaatcc 780 ccgcgggttg gtcggggctg gggcggggct cgggggacgg ggctgaccac gggggcgggg 840 ccagggtctc acaccctcca gaggatgtat ggctgcgacc tggggcccga cgggcgcctc 900 ctccgcgggt ataaccagtt cgcctacgac ggcaaggatt acatcgccct gaatgaggac 960 ctgcgctcct ggaccgccgc ggacaaggcg gctcagatca cccagcgcaa gtgggaggcg 1020 gcccgtgagg cggagcagtg gagagcctac ctggagggca cgtgcgtgga gtggctccgc 1080 agatacctgg agaacgggaa gaagacgctg cagcgcgcgg gtaccagggg cagtggggag 1140 ccttccccat ctcctgtaga tctcccggga tggcctccca cgaggagggg aggaaaatgg 1200 gatcagcgct ggaatatcgc cctcccttga atggagaatg ggatgagttt tcctgagttt 1260 cttctgaggg ccccctctgc tctctaggac aattaaggga tgaagtcctt gaggaaatgg 1320 aggggaagac agtccctgga atactgatca ggggtcccct ttgaccactt tgaccactgc 1380 agcagctgtg gtcaggctgc tgacctttct ctcaggcctt gttctctgcc tcacgctcaa 1440 tgtgtttaaa ggtttgattc cagcttttct gagtccttcg gcctccactc aggtcaggac 1500 cagaagtcgc tgttcctccc tcagagacta gaactttcca atgaatagga gattatccca 1560 ggtgcctgtg tccaggctgg cgtctgggtt ctgtgccccc ttccccaccc caggtgtcct 1620 gtccattctc aggatggtca catgggcact gttggagtgt cgcaagagag atacaaagtg 1680 tctgaatttt ctgactcttc ccgtcagaac acccaaagac acacgtgacc caccatcccg 1740 tctctgacca tgaggccacc ctgaggtgct gggccctggg cttctaccct gcggagatca 1800 cactgacctg gcagcgggat ggcgaggacc aaactcagga caccgagctt gtggagacca 1860 ggccagcagg agatggaacc ttccagaagt gggcagctgt ggtggtgcct tctggagaag 1920 agcagagata cacgtgccat gtgcagcacg aggggctgcc agagcccctc accctgagat 1980 ggggtaagga gggggatgag gggtcatgtg tcttctcagg gaaagcagaa gtcctggagc 2040 ccttcagccg ggtcagggct gaggcttggg ggtcagggcc cctcaccttc ccctcctttc 2100 ccagggccat cttcccagcc caccatcccc atcgtgggca tcgttgctgg cctggctgtc 2160 ctggctgtcc tagctgtcct aggagctgtg atggctgttg tgatgtgtag gaggaagagc 2220 tcaggtaggg aaggggtgag gagtggggtc tgggttttct tgtcccactg ggagtttcaa 2280 gccccaggta gaagtgtgcc ccacctcgtt actggaagca ccatccacac atgggccatc 2340 ccagcctggg accctgtgtg ctagcactta ctctgttgtg aagcacatga caatgaagga 2400 cagatgtatc accttgatga ttatggtgtt ggggtccttg attccagcat tcatgagtca 2460 ggggaaggtc cctgctaagg acagacctta ggagggcagt tgctccagaa cccacagctg 2520 ctttccccgt gtttcctgat cctgccctgg gtctgcagtc atagttctgg aaacttctct 2580 tgggtccaag actaggaggt tcccctaaga tcgcatggcc ctgcctcctc cctgtcccct 2640 cacagggcat tttcttccca caggtggaaa aggagggagc tgctctcagg ctgcgtgtaa 2700 gtgatggcgg tgggcgtgtg gaggagctca cccaccccat aattcctctt gtcccacatc 2760 tcctgcgggc tctgaccagg tctttttttt tgttctaccc cagccagcaa cagtgcccag 2820 ggctctgatg agtctctcat cgcttgtaaa ggtgagattc tggggagctg aagtggtcgg 2880 gggtggggca gagggaaaag gcctaggtaa tggggatcct ttgattggga cgtttcgaat 2940 gtgtggtgag ctgttcagag tgtcatcact taccatgact gacctgaatt tgttcatgac 3000 tattgtgttc tgtagcctga gacagctgcc tgtgtgggac tgagatgcag gatttcttc 3059 //