ID AJ865349; SV 1; linear; genomic DNA; STD; HUM; 781 BP.
XX
AC AJ865349;
XX
DT 24-NOV-2004 (Rel. 81, Created)
DT 17-JUN-2008 (Rel. 96, Last updated, Version 4)
XX
DE Homo sapiens partial HLA-A gene for MHC class I antigen, HLA-A*74del
DE allele, exons 2-3
XX
KW HLA-A gene; HLA-A*74del allele; human leucocyte antigen B;
KW major histocompatibility complex; MHC class I antigen.
XX
OS Homo sapiens (human)
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
XX
RN [1]
RP 1-781
RA Witter K.;
RT ;
RL Submitted (23-NOV-2004) to the INSDC.
RL Witter K., University of Munich, Labor of Immunogenetics, Paul Heyse
RL Strasse 33, 80336 Munich, GERMANY.
XX
RN [2]
RA Witter K., Mautner J., Volgger A., Albert E.D.;
RT "A novel HLA-A*74 allele detected in a leukocyte cell line possessed a
RT deletion of two amino acids in beginning of exon 3";
RL Unpublished.
XX
DR MD5; d3e79899661e843a4c3ec3f825aac0e4.
XX
FH Key Location/Qualifiers
FH
FT source 1..781
FT /organism="Homo sapiens"
FT /isolate="153152"
FT /mol_type="genomic DNA"
FT /cell_type="leucocyte"
FT /germline
FT /db_xref="taxon:9606"
FT CDS join(<1..270,512..>781)
FT /codon_start=3
FT /gene="HLA-A"
FT /allele="HLA-A*74del"
FT /product="MHC class I antigen"
FT /function="antigen presenting molecule"
FT /db_xref="IMGT/HLA:A*74:12N"
FT /db_xref="InterPro:IPR001039"
FT /db_xref="InterPro:IPR011161"
FT /db_xref="InterPro:IPR011162"
FT /db_xref="InterPro:IPR037055"
FT /db_xref="UniProtKB/TrEMBL:Q5TIL1"
FT /protein_id="CAI26292.1"
FT /translation="SHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRME
FT PRAPWIEQEGPEYWDQETRNVKAHSQTDRVDLGTLRGYYNQSEAGSHTMMYGCDVGPDG
FT RLLRGYQQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWEAARVAEQLRAYLEGTCVE
FT WLRRYLENGKETLQRT"
FT mRNA join(<1..270,512..>781)
FT /gene="HLA-A"
FT /allele="HLA-A*74del"
FT exon 1..270
FT /gene="HLA-A"
FT /allele="HLA-A*74del"
FT /number=2
FT intron 271..511
FT /gene="HLA-A"
FT /allele="HLA-A*74del"
FT /number=2
FT exon 512..781
FT /gene="HLA-A"
FT /allele="HLA-A*74del"
FT /number=3
FT variation 524^525
FT /allele="HLA-A*7401"
FT /replace="ccagat"
FT /compare=U17570.1
XX
SQ Sequence 781 BP; 139 A; 246 C; 284 G; 112 T; 0 other;
gctcccactc catgaggtat ttcttcacat ccgtgtcccg gcccggccgc ggggagcccc 60
gcttcatcgc cgtgggctac gtggacgaca cgcagttcgt gcggtttgac agcgacgccg 120
cgagccagag gatggagccg cgggcgccgt ggatagagca ggaggggccg gagtattggg 180
accaggagac acggaatgtg aaggcccact cacagactga ccgagtggac ctggggaccc 240
tgcgcggcta ctacaaccag agcgaggccg gtgagtgacc ccggccgggg gcgcaggtca 300
ggacccctca tcccccacgg acgggccagg tcgcccacag tctccgggtc cgagatccac 360
cccgaagccg cgggaccccg agacccttgc cccgggagag gcccaggcgc ctttacccgg 420
tttcattttc agtttaggcc aaaaatcccc ccgggttggt cggggccgga cggggctcgg 480
gggactgggc tgaccgtggg gtcggggcca ggttctcaca ccatgatgta tggctgcgac 540
gtggggccgg acgggcgcct cctccgcggg taccagcagg acgcctacga cggcaaggat 600
tacatcgcct tgaacgagga cctgcgctct tggaccgcgg cggacatggc ggctcagatc 660
acccagcgca agtgggaggc ggcccgtgtg gcggagcagt tgagagccta cctggagggc 720
acgtgcgtgg agtggctccg cagatacctg gagaacggga aggagacgct gcagcgcacg 780
g 781
//
