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EBI Dbfetch

ID   AJ556174; SV 1; linear; genomic DNA; STD; HUM; 1110 BP.
XX
AC   AJ556174;
XX
DT   14-APR-2004 (Rel. 79, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 4)
XX
DE   Homo sapiens HLA-B gene for MHC class I antigen, HLA-B*1524 allele
XX
KW   HLA-B gene; HLA-B*1524 allele; human leucocyte antigen B;
KW   major histocompatibility complex; MHC class I antigen.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-1110
RA   Vilches C.;
RT   ;
RL   Submitted (14-APR-2003) to the INSDC.
RL   Vilches C., Inmunologia, H.U. Puerta de Hierro, 4 San Martin de Porres,
RL   28035, SPAIN.
XX
RN   [3]
RX   DOI; 10.1111/j.1399-0039.2005.00407.x.
RX   PUBMED; 15896200.
RA   Vilches C., Sepulveda S., Balas A., Solis R., Aviles M.J., Estefania E.,
RA   Gomez-Lozano N., Vicario J.L., DePablo R.;
RT   "Complete coding sequences and haplotypic associations of HLA-B*0707,
RT   -B*1524, -B*4405, -B*4802, -DRB1*0409, -DRB1*0411, -DRB1*1115, -DRB1*1305,
RT   and the novel allele -DRB1*0709. Group-specific amplification of cDNA from
RT   DRB1 alleles associated to DRB3 and DRB4";
RL   Tissue Antigens 65(6):529-538(2005).
XX
DR   MD5; 0296793b73daa0adedb1f052a4427990.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1110
FT                   /organism="Homo sapiens"
FT                   /mol_type="genomic DNA"
FT                   /country="Spain"
FT                   /cell_line="HSV48"
FT                   /cell_type="B-lymphocyte"
FT                   /tissue_type="peripheral blood"
FT                   /db_xref="taxon:9606"
FT   CDS             5..1093
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*1524"
FT                   /product="MHC class I antigen"
FT                   /function="antigen presenting molecule"
FT                   /db_xref="GOA:Q70Q09"
FT                   /db_xref="IMGT/HLA:B*15:24:01"
FT                   /db_xref="InterPro:IPR001039"
FT                   /db_xref="InterPro:IPR003006"
FT                   /db_xref="InterPro:IPR003597"
FT                   /db_xref="InterPro:IPR007110"
FT                   /db_xref="InterPro:IPR010579"
FT                   /db_xref="InterPro:IPR011161"
FT                   /db_xref="InterPro:IPR011162"
FT                   /db_xref="InterPro:IPR013783"
FT                   /db_xref="InterPro:IPR027648"
FT                   /db_xref="UniProtKB/TrEMBL:Q70Q09"
FT                   /protein_id="CAD89004.1"
FT                   /translation="MRVTAPRTVLLLLSGALALTETWAGSHSMRYFYTAMSRPGRGEPR
FT                   FIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDRETQISKTNTQTYRENLRI
FT                   ALRYYNQSEAGSHTLQRMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTA
FT                   AQITQRKWEAAREAEQWRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHE
FT                   ATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRY
FT                   TCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLAVVVIGAVVATVMCRRKSSGGK
FT                   GGSYSQAASSDSAQGSDVSLTA"
FT   sig_peptide     5..76
FT                   /gene="HLA-B"
FT   mat_peptide     77..1090
FT                   /gene="HLA-B"
FT                   /product="MHC class I antigen"
XX
SQ   Sequence 1110 BP; 228 A; 344 C; 365 G; 173 T; 0 other;
     cgagatgcgg gtcacggcgc cccgaaccgt cctcctgctg ctctcgggag ccctggccct        60
     gaccgagacc tgggccggct cccactccat gaggtatttc tacaccgcca tgtcccggcc       120
     cggccgcggg gagccccgct tcatcgcagt gggctacgtg gacgacaccc agttcgtgag       180
     gttcgacagc gacgccgcga gtccgaggat ggcgccccgg gcgccatgga tagagcagga       240
     ggggccggag tattgggacc gggagacaca gatctccaag accaacacac agacttaccg       300
     agagaacctg cggatcgcgc tccgctacta caaccagagc gaggccgggt ctcacaccct       360
     ccagaggatg tacggctgcg acgtggggcc ggacgggcgc ctcctccgcg ggcatgacca       420
     gtccgcctac gacggcaagg attacatcgc cctgaacgag gacctgagct cctggaccgc       480
     ggcggacacg gcggctcaga tcacccagcg caagtgggag gcggcccgtg aggcggagca       540
     gtggagagcc tacctggagg gcctgtgcgt ggagtggctc cgcagatacc tggagaacgg       600
     gaaggagacg ctgcagcgcg cggacccccc aaagacacat gtgacccacc accccatctc       660
     tgaccatgag gccaccctga ggtgctgggc cctgggcttc taccctgcgg agatcacact       720
     gacctggcag cgggatggcg aggaccaaac tcaggacacc gagcttgtgg agaccagacc       780
     agcaggagat agaaccttcc agaagtgggc agctgtggtg gtgccttctg gagaagagca       840
     gagatacaca tgccatgtac agcatgaggg gctgccgaag cccctcaccc tgagatggga       900
     gccatcttcc cagtccacca tccccatcgt gggcattgtt gctggcctgg ctgtcctagc       960
     agttgtggtc atcggagctg tggtcgctac tgtgatgtgt aggaggaaga gctcaggtgg      1020
     aaaaggaggg agctactctc aggctgcgtc cagcgacagt gcccagggct ctgatgtgtc      1080
     tctcacagct tgaaaagcct gagacagctg                                       1110
//


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