Dbfetch

ID   AJ549202; SV 3; linear; genomic DNA; STD; HUM; 3142 BP.
XX
AC   AJ549202;
XX
DT   04-MAY-2003 (Rel. 75, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 6)
XX
DE   Homo sapiens HLA-B gene for MHC class I antigen, HLA-B*08xx allele, exons
DE   1-7
XX
KW   HLA-B gene; HLA-B*08xx allele; human leucocyte antigen B;
KW   major histocompatibility complex; MHC class I antigen.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RC   revised by [3]
RA   Cox S.T.;
RT   ;
RL   Submitted (04-MAR-2003) to the INSDC.
RL   Cox S.T., Dept. of HLA Sequencing, Anthony Nolan Research, The Royal Free
RL   Hospital, Pond Street, Hampstead, London, NW3 2QG, UNITED KINGDOM.
XX
RN   [2]
RA   Cox S.T.;
RT   "Sequence of X new HLA class I alleles";
RL   Unpublished.
XX
RN   [3]
RC   revised by [4]
RA   Cox S.T.;
RT   ;
RL   Submitted (20-MAY-2003) to the INSDC.
RL   Cox S.T., Dept. of HLA Sequencing, Anthony Nolan Research, The Royal Free
RL   Hospital, Pond Street, Hampstead, London, NW3 2QG, UNITED KINGDOM.
XX
RN   [4]
RP   1-3142
RA   Cox S.T.;
RT   ;
RL   Submitted (24-JAN-2006) to the INSDC.
RL   Cox S.T., Dept. of HLA Sequencing, Anthony Nolan Research, The Royal Free
RL   Hospital, Pond Street, Hampstead, London, NW3 2QG, UNITED KINGDOM.
XX
DR   MD5; 87b3e096137c9cf41e7cc3f8c429bb47.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..3142
FT                   /organism="Homo sapiens"
FT                   /chromosome="6p21.3"
FT                   /mol_type="genomic DNA"
FT                   /tissue_type="blood"
FT                   /db_xref="taxon:9606"
FT   CDS             join(302..374,503..772,1019..1294,1867..2142,2236..2352,
FT                   2794..2826,2933..2976)
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*08xx"
FT                   /product="MHC class I antigen"
FT                   /function="antigen presenting molecule"
FT                   /db_xref="GOA:Q7YQ88"
FT                   /db_xref="IMGT/HLA:B*08:20"
FT                   /db_xref="InterPro:IPR001039"
FT                   /db_xref="InterPro:IPR003006"
FT                   /db_xref="InterPro:IPR003597"
FT                   /db_xref="InterPro:IPR007110"
FT                   /db_xref="InterPro:IPR010579"
FT                   /db_xref="InterPro:IPR011161"
FT                   /db_xref="InterPro:IPR011162"
FT                   /db_xref="InterPro:IPR013783"
FT                   /db_xref="InterPro:IPR036179"
FT                   /db_xref="InterPro:IPR037055"
FT                   /db_xref="UniProtKB/TrEMBL:Q7YQ88"
FT                   /protein_id="CAD79565.2"
FT                   /translation="MLVMAPRTVLLLLSAALALTETWAGSHSMRYFDTAMSRPGRGEPR
FT                   FISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIFKTNTQTDRESLRN
FT                   LRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTA
FT                   AQITQRKWEAAREAEQRRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHE
FT                   ATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRY
FT                   TCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGK
FT                   GGSYSQAACSDSAQGSDVSLTA"
FT   exon            <302..374
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*08xx"
FT                   /number=1
FT   intron          375..502
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*08xx"
FT                   /number=1
FT   exon            503..772
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*08xx"
FT                   /number=2
FT   intron          773..1018
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*08xx"
FT                   /number=2
FT   exon            1019..1294
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*08xx"
FT                   /number=3
FT   intron          1295..1866
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*08xx"
FT                   /number=3
FT   exon            1867..2142
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*08xx"
FT                   /number=4
FT   intron          2143..2235
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*08xx"
FT                   /number=4
FT   exon            2236..2352
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*08xx"
FT                   /number=5
FT   intron          2353..2793
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*08xx"
FT                   /number=5
FT   exon            2794..2826
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*08xx"
FT                   /number=6
FT   intron          2827..2932
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*08xx"
FT                   /number=6
FT   exon            2933..2976
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*08xx"
FT                   /number=7
XX
SQ   Sequence 3142 BP; 581 A; 917 C; 1007 G; 637 T; 0 other;
     tggtgtagga gaagagggat caggacgaag tcccaggtcc cggacggggc tctcagggtc        60
     tcaggctccg agggccgcgt ctgcaatggg gaggcgcagc gttggggatt ccccactccc       120
     ctgagtttca cttcttctcc caacttgtgt cgggtccttc ttccaggata ctcgtgacgc       180
     atccccactt cccactccca ttgggtgtcg gatatctaga gaagccaatc agcgtcgccg       240
     gggtcccagt tctaaagtcc ccacgcaccc acccggactc agagtctcct cagacgccga       300
     gatgctggtc atggcgcccc gaaccgtcct cctgctgctc tcggcggccc tggccctgac       360
     cgagacctgg gccggtgagt gcgggtcggg agggaaatgg cctctgccgg gaggagcgag       420
     gggaccgcag gcgggggcgc aggacctgag gagccgcgcc gggaggaggg tcgggcgggt       480
     ctcagcccct cctcgccccc aggctcccac tccatgaggt atttcgacac cgccatgtcc       540
     cggcccggcc gcggggagcc ccgcttcatc tcagtgggct acgtggacga cacgcagttc       600
     gtgaggttcg acagcgacgc cgcgagtccg agagaggagc cgcgggcgcc gtggatagag       660
     caggaggggc cggagtattg ggaccggaac acacagatct tcaagaccaa cacacagact       720
     gaccgagaga gcctgcggaa cctgcgcggc tactacaacc agagcgaggc cggtgagtga       780
     ccccggcccg gggcgcaggt cacgactccc catcccccac ggacggcccg ggtcgccccg       840
     agtctccggg tccgagatcc gcctccctga ggccgcggga cccgcccaga ccctcgaccg       900
     gcgagagccc caggcgcgtt tacccggttt cattttcagt tgaggccaaa atccccgcgg       960
     gttggtcggg gcggggcggg gctcgggggg acggggctga ccgcggggcc ggggccaggg      1020
     tctcacaccc tccagagcat gtacggctgc gacgtggggc cggacgggcg cctcctccgc      1080
     gggcataacc agtacgccta cgacggcaag gattacatcg ccctgaacga ggacctgcgc      1140
     tcctggaccg ccgcggacac cgcggctcag atcacccagc gcaagtggga ggcggcccgt      1200
     gaggcggagc agcggagagc ctacctggag ggcacgtgcg tggagtggct ccgcagatac      1260
     ctggagaacg ggaaggacac gctggagcgc gcgggtacca ggggcagtgg ggagccttcc      1320
     ccatctccta taggtcgccg gggatggcct cccacgagaa gaggaggaaa atgggatcag      1380
     cgctagaatg tcgccctccc ttgaatggag aatggcatga gttttcctga gtttcctatg      1440
     agggccccct cttctctcta gacaattaag ggatgacgtc tctgaggaaa tggaggggaa      1500
     gacagtccct agaatactga tcaggggtcc cctttgaccc ctgcagcagc cttgggaacc      1560
     gtgacttttc ctctcaggcc ttgttctctg cctcacactc agtgtgtttg gggctctgat      1620
     tccagcactt ctgagtcact ttacctccac tcagatcagg agcagaagtc cctgttcccc      1680
     gctcagagac tcgaactttc caatgaatag gagattatcc caggtgcctg catccgctgg      1740
     tgtctgggtt ctgtgcccct tccccacccc aggtgtcctg tccattctca ggctggtcac      1800
     atgggtggtc ctagggtgtg ccatgagaga tgcaaagcgc ctgaattttc tgactcttcc      1860
     catcagaccc cccaaagaca cacgtgaccc accaccccat ctctgaccat gaggccaccc      1920
     tgaggtgctg ggccctgggc ttctaccctg cggagatcac actgacctgg cagcgggatg      1980
     gcgaggacca aactcaggac actgagcttg tggagaccag accagcagga gatagaacct      2040
     tccagaagtg ggcagctgtg gtggtgcctt ctggagaaga gcagagatac acatgccatg      2100
     tacagcatga ggggctgccg aagcccctca ccctgagatg gggtaaggag ggggatgagg      2160
     ggtcatatct cttctcaggg aaagcaggag cccttcagca gggtcagggc ccctcatctt      2220
     cccctccttt cccagagccg tcttcccagt ccaccgtccc catcgtgggc attgttgctg      2280
     gcctggctgt cctagcagtt gtggtcatcg gagctgtggt cgctgctgtg atgtgtagga      2340
     ggaagagctc aggtagggaa ggggtgaggg gtggggtctg ggttttcttg tcccactggg      2400
     ggtttcaagc cccaggtaga agtgttccct gcctcattac tgggatgcag catccacaca      2460
     ggggctaacg cagcctggga ccctgtgtgc cagcacttac tcttttgtgc agcacatgtg      2520
     acaatgaagg acggatgtat caccttggtg gttgtggtgt tggggtcctg attccagcat      2580
     tcatgagtca ggggaaggtc cctgctaagg acagacctta ggagggcagt tggtccagga      2640
     cccacacttg ctttcctcgt gtttcctgat cctgccttgg gtctgtagtc atacttctgg      2700
     aaattccttt tgggtccaag acgaggaggt tcctctaaga tctcatggcc ctgcttcctc      2760
     ccagtcccct cacagggcat tttcttccca caggtggaaa aggagggagc tactctcagg      2820
     ctgcgtgtaa gtgatggggg tgggagtgtg gaggagctca cccaccccat aattcctcct      2880
     gtcccacgtc tcctgcgggc tctgaccagg tcctgttttt gttctactcc aggcagcgac      2940
     agtgcccagg gctctgatgt gtctctcaca gcttgaaaag gtgagattct tggggtctag      3000
     agtgggtggg gtggcgggtc tgggggtggg tggggcagtg gggaaaggcc tgggtaatgg      3060
     agattctttg attgggatgt ttcgcgtgtg tggtgggctg tttagagtgt catcacttac      3120
     catgactaac cagaatttgt tc                                               3142
//