Dbfetch
ID AJ311600; SV 2; linear; genomic DNA; STD; HUM; 3387 BP.
XX
AC AJ311600;
XX
DT 29-MAR-2001 (Rel. 67, Created)
DT 17-JUN-2008 (Rel. 96, Last updated, Version 5)
XX
DE Homo sapiens HLA-B gene for MHC class I antigen, allele B*4901, exons 1-7
XX
KW HLA-B gene; HLA-B*4901 allele; human leucocyte antigen B;
KW major histocompatibility complex; MHC class I antigen.
XX
OS Homo sapiens (human)
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
XX
RN [1]
RC revised by [3]
RA Cox S.T.;
RT ;
RL Submitted (01-MAR-2001) to the INSDC.
RL Cox S.T., Dept of HLA Sequencing, Anthony Nolan Research, The Royal Free
RL Hospital, Pond Street, Hampstead, London, NW3 2QG, UNITED KINGDOM.
XX
RN [2]
RA Cox S.T.;
RT "Confirmation of HLA-B*4901";
RL Unpublished.
XX
RN [3]
RP 1-3387
RA Cox S.T.;
RT ;
RL Submitted (12-NOV-2004) to the INSDC.
RL Cox S.T., Dept of HLA Sequencing, Anthony Nolan Research, The Royal Free
RL Hospital, Pond Street, Hampstead, London, NW3 2QG, UNITED KINGDOM.
XX
DR MD5; be744974475e6f888dc3bd55e941a650.
XX
FH Key Location/Qualifiers
FH
FT source 1..3387
FT /organism="Homo sapiens"
FT /chromosome="6"
FT /map="6p21.31"
FT /mol_type="genomic DNA"
FT /tissue_type="blood"
FT /note="confirmation of HLA B*4901 from cell AM"
FT /db_xref="taxon:9606"
FT mRNA join(<302..374,503..772,1023..1298,1874..2149,2254..2370,
FT 2812..2844,2951..>2994)
FT /gene="HLA-B"
FT /product="MHC class I antigen"
FT /note="B*4901 allele"
FT CDS join(302..374,503..772,1023..1298,1874..2149,2254..2370,
FT 2812..2844,2951..2994)
FT /gene="HLA-B"
FT /product="MHC class I antigen"
FT /function="antigen presentation"
FT /note="B*4901 allele"
FT /db_xref="GOA:Q5TK75"
FT /db_xref="IMGT/HLA:B*49:01:01"
FT /db_xref="InterPro:IPR001039"
FT /db_xref="InterPro:IPR003006"
FT /db_xref="InterPro:IPR003597"
FT /db_xref="InterPro:IPR007110"
FT /db_xref="InterPro:IPR010579"
FT /db_xref="InterPro:IPR011161"
FT /db_xref="InterPro:IPR011162"
FT /db_xref="InterPro:IPR013783"
FT /db_xref="InterPro:IPR036179"
FT /db_xref="InterPro:IPR037055"
FT /db_xref="UniProtKB/TrEMBL:Q5TK75"
FT /protein_id="CAC35318.1"
FT /translation="MRVTAPRTVLLLLSAALALTETWAGSHSMRYFHTAMSRPGRGEPR
FT FITVGYVDDTLFVRFDSDATSPRKEPRAPWIEQEGPEYWDRETQISKTNTQTYRENLRI
FT ALRYYNQSEAGSHTWQRMYGCDLGPDGRLLRGYNQLAYDGKDYIALNEDLSSWTAADTA
FT AQITQRKWEAAREAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHE
FT ATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRY
FT TCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLAVVVIGAVVATVMCRRKSSGGK
FT GGSYSQAASSDSAQGSDVSLTA"
FT exon 302..374
FT /gene="HLA-B"
FT /number=1
FT /note="B*4901 allele"
FT intron 375..502
FT /gene="HLA-B"
FT /number=1
FT /note="B*4901 allele"
FT exon 503..772
FT /gene="HLA-B"
FT /number=2
FT /note="B*4901 allele"
FT intron 773..1022
FT /gene="HLA-B"
FT /number=2
FT /note="B*4901 allele"
FT exon 1023..1298
FT /gene="HLA-B"
FT /number=3
FT /note="B*4901 allele"
FT intron 1299..1873
FT /gene="HLA-B"
FT /number=3
FT /note="B*4901 allele"
FT exon 1874..2149
FT /gene="HLA-B"
FT /number=4
FT /note="B*4901 allele"
FT intron 2150..2253
FT /gene="HLA-B"
FT /number=4
FT /note="B*4901 allele"
FT exon 2254..2370
FT /gene="HLA-B"
FT /number=5
FT /note="B*4901 allele"
FT intron 2371..2811
FT /gene="HLA-B"
FT /number=5
FT /note="B*4901 allele"
FT exon 2812..2844
FT /gene="HLA-B"
FT /number=6
FT /note="B*4901 allele"
FT intron 2845..2950
FT /gene="HLA-B"
FT /number=6
FT /note="B*4901 allele"
FT exon 2951..2994
FT /gene="HLA-B"
FT /number=7
FT /note="B*4901 allele"
XX
SQ Sequence 3387 BP; 626 A; 985 C; 1064 G; 712 T; 0 other;
tggtgtagga gaagagggat caggacgaag tcccaggccc cgggcggggc tctcagggtc 60
tcaggctccg agggccgcgt ctgcaatggg gaggcgcagc gttggggatt ccccactccc 120
acgagtttca cttcttctcc caacctatgt cgggtccttc ttccaggata ctcgtgacgc 180
gtccccattt cccactccca ttgggtgtcg ggtgtctaga gaagccaatc agcgtcgccg 240
tggtcccagt tctaaagtcc ccacgcaccc acccggactc agaatctcct cagacgccga 300
gatgcgggtc acggcacccc gaaccgtcct cctgctgctc tcggcggccc tggccctgac 360
cgagacctgg gccggtgagt gcgggtcggc agggaaatgg cctctgtggg gaggagcgag 420
gggaccgcag gcgggggcgc aggacccggg gagccgcgcc gggaggaggg tcgggcgggt 480
ctcagcccct cctcgccccc aggctcccac tccatgaggt atttccacac cgccatgtcc 540
cggcccggcc gcggggagcc ccgcttcatc accgtgggct acgtggacga cacgctgttc 600
gtgaggttcg acagcgacgc cacgagtccg aggaaggagc cgcgggcgcc atggatagag 660
caggaggggc cggagtattg ggaccgggag acacagatct ccaagaccaa cacacagact 720
taccgagaga acctgcggat cgcgctccgc tactacaacc agagcgaggc cggtgagtga 780
ccccggcccg gggcgcaggt cacgactccc catcccccac gtacggcccg ggtcgccccg 840
agtctccggg tccgagatcc gcccccctga ggccgcggga cccgcccaga ccctcgaccg 900
gcgagagccc caggcgcgtt tacccggttt cattttcagt tgaggccaaa atccccgcgg 960
gttggtcggg gcggggcggg gcggggctcg ggggacgggg ctgaccgcgg ggcctgggcc 1020
agggtctcac acttggcaga ggatgtatgg ctgcgacctg gggcccgacg ggcgcctcct 1080
ccgcgggtat aaccagttag cctacgacgg caaggattac atcgccctga acgaggacct 1140
gagctcctgg accgcggcgg acaccgcggc tcagatcacc cagcgcaagt gggaggcggc 1200
ccgtgaggcg gagcagctga gagcctacct ggagggcctg tgcgtggagt ggctccgcag 1260
atacctggag aacgggaagg agacgctgca gcgcgcgggt accaggggca gtggggagcc 1320
ttccccatct cctataggtc gccggggatg gcctcccacg agaagaggag gaaaatggga 1380
tcagcgctag aatgtcgccc tcccttgaat ggagaatggc atgagttttc ctgagtttcc 1440
tctgagggcc ccctcttctc tctaggacaa ttaagggatg acgtctctga ggaaatggag 1500
gggaagacag tccctagaat actgatcagg ggtccccttt gacccctgca gcagccttgg 1560
gaaccgtgac ttttcctctc aggccttgtt ctctgcctca cactcagtgt gtttggggct 1620
ctgattccag cacttctgag tcactttacc tccactcaga tcaggagcag aagtccctgt 1680
tccccactca gagactcgaa ctttccaatg aataggagat tatcccaggt gcctgcgtcc 1740
aggctggtgt ctgggttctg tgccccttcc ccaccccagg tgtcctgtcc attctcaggc 1800
tggtcacatg ggtggtccta gggtgtccca tgagagatgc aaagcgcctg aattttctga 1860
ctcttcccat cagacccccc aaagacacat gtgacccacc accccatctc tgaccatgag 1920
gccaccctga ggtgctgggc cctgggcttc taccctgcgg agatcacact gacctggcag 1980
cgggatggcg aggaccaaac tcaggacacc gagcttgtgg agaccagacc agcaggagat 2040
agaaccttcc agaagtgggc agctgtggtg gtgccttctg gagaagagca gagatacaca 2100
tgccatgtac agcatgaggg gctgccgaag cccctcaccc tgagatgggg taaggagggg 2160
gatgaggggt catatctgtt ctcagggaaa gcaggagccc ttctggagcc cttcagcagg 2220
gtcagggccc ctcatcttcc cctcctttcc cagagccatc ttcccagtcc accatcccca 2280
tcgtgggcat tgttgctggc ctggctgtcc tagcagttgt ggtcatcgga gctgtggtcg 2340
ctactgtgat gtgtaggagg aagagctcag gtagggaagg ggtgaggggt ggggtctggg 2400
ttttcttgtc ccactggggg tttcaagccc caggtagaag tgttccctgc ctcattactg 2460
ggaagcagca tccacacagg ggctaacgca gcctgggacc ctgtgtgcca gcacttactc 2520
ttttgtgcag cacatgtgac aatgaaggac ggatgtatcg ccttgatggt tgtggtgttg 2580
gggtcctgat tccagcattc atgagtcagg ggaaggtccc tgctaaggac agaccttagg 2640
agggcagttg gtccaggacc cacacttgct ttcctcgtgt ttcctgatcc tgccttgggt 2700
ctgtagtcat acttctggaa attccttttg gttccaagac gaggaggttc ctctaagatc 2760
tcatggccct gcttcctccc agtcccctca caggacattt tcttcccaca ggtggaaaag 2820
gagggagcta ctctcaggct gcgtgtaagt ggtgggggtg ggagtgtgga ggagctcacc 2880
caccccataa ttcctcctgt cccacgtctc ctgagggctc tgaccaggtc ctgtttttgt 2940
tctactccag ccagcgacag tgcccagggc tctgatgtgt ctctcacagc ttgaaaaggt 3000
gagattcttg gggtctagag tgggtggggt ggcgggtctg ggggtgggtg gggcagtggg 3060
gaaaggcctg ggtaatggag attctttgat tgggatgttt cgcgtgtgtg gtgggctgtt 3120
cagagtgtca tcacttacca tgactaacca gaatttgttc atgactgttg ttttctgtag 3180
cctgagacag ctgtcttgtg agggactgag atgcaggatt tcttcacgcc tcccctttgt 3240
gacttcaaga gcctctggca tctctttctg caaaggcacc tgaatgtgtc tgcgtccctg 3300
ttagcataat gtgaggaggt ggagagacag cccacccttg tgtccactgt gacccctgtt 3360
cgcatgctga cctgtgtttc ctcccca 3387
//
