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EBI DbfetchID AJ310509; SV 1; linear; genomic DNA; STD; HUM; 3457 BP. XX AC AJ310509; XX DT 17-MAR-2001 (Rel. 67, Created) DT 17-JUN-2008 (Rel. 96, Last updated, Version 4) XX DE Homo sapiens HLA-B gene for MHC class I antigen, allele B*5501; exons 1-7 XX KW B*5501 allele; HLA-B gene; human leukocyte antigen B; KW major histocompatibility complex; MHC class I antigen. XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-3457 RA Cox S.T.; RT ; RL Submitted (14-FEB-2001) to the INSDC. RL Cox S.T., Dept of HLA Sequencing, Anthony Nolan Research, The Royal Free RL Hospital, Pond Street, Hampstead, London, NW3 2QG, UNITED KINGDOM. XX RN [2] RA Cox S.T.; RT "Confirmation of HLA-B*5501"; RL Unpublished. XX DR Ensembl-Gn; ENSG00000206450; homo_sapiens. DR Ensembl-Tr; ENST00000359635; homo_sapiens. XX FH Key Location/Qualifiers FH FT source 1..3457 FT /organism="Homo sapiens" FT /chromosome="6p21.31" FT /mol_type="genomic DNA" FT /tissue_type="blood" FT /db_xref="taxon:9606" FT mRNA join(302..374,503..772,1018..1293,1869..2144,2249..2365, FT 2807..2839,2946..2989) FT /gene="HLA-B" FT /note="B*5501" FT /citation=[2] FT CDS join(302..374,503..772,1018..1293,1869..2144,2249..2365, FT 2807..2839,2946..2989) FT /gene="HLA-B" FT /product="HLA-B" FT /function="antigen presentation" FT /note="B*5501" FT /db_xref="GOA:P30493" FT /db_xref="HGNC:HGNC:4932" FT /db_xref="IMGT/HLA:B*55:01:01" FT /db_xref="InterPro:IPR001039" FT /db_xref="InterPro:IPR003006" FT /db_xref="InterPro:IPR003597" FT /db_xref="InterPro:IPR007110" FT /db_xref="InterPro:IPR010579" FT /db_xref="InterPro:IPR011161" FT /db_xref="InterPro:IPR011162" FT /db_xref="InterPro:IPR013783" FT /db_xref="InterPro:IPR027648" FT /db_xref="UniProtKB/Swiss-Prot:P30493" FT /citation=[2] FT /protein_id="CAC34574.1" FT /translation="MRVTAPRTLLLLLWGALALTETWAGSHSMRYFYTAMSRPGRGEPR FT FIAVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRN FT LRGYYNQSEAGSHTWQTMYGCDLGPDGRLLRGHNQLAYDGKDYIALNEDLSSWTAADTA FT AQITQRKWEAAREAEQLRAYLEGTCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHE FT ATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRY FT TCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLAVVVIGAVVATVMCRRKSSGGK FT GGSYSQAASSDSAQGSDVSLTA" FT exon 302..374 FT /gene="HLA-B" FT /number=1 FT /note="B*5501" FT intron 375..502 FT /gene="HLA-B" FT /number=1 FT /note="B*5501" FT exon 503..772 FT /gene="HLA-B" FT /number=2 FT /note="B*5501" FT intron 773..1017 FT /gene="HLA-B" FT /number=2 FT /note="B*5501" FT exon 1018..1293 FT /gene="HLA-B" FT /number=3 FT /note="B*5501" FT intron 1294..1868 FT /gene="HLA-B" FT /number=3 FT /note="B*5501" FT exon 1869..2144 FT /gene="HLA-B" FT /number=4 FT /note="B*5501" FT intron 2145..2248 FT /gene="HLA-B" FT /number=4 FT /note="B*5501" FT exon 2249..2365 FT /gene="HLA-B" FT /number=5 FT /note="B*5501" FT intron 2366..2806 FT /gene="HLA-B" FT /number=5 FT /note="B*5501" FT exon 2807..2839 FT /gene="HLA-B" FT /number=6 FT /note="B*5501" FT intron 2840..2945 FT /gene="HLA-B" FT /number=6 FT /note="B*5501" FT exon 2946..2989 FT /gene="HLA-B" FT /number=7 FT /note="B*5501" XX SQ Sequence 3457 BP; 643 A; 995 C; 1093 G; 725 T; 1 other; tggtgtagga gaagagggat caggacgaag tcccatgtcc cggacggggc tctcagggtc 60 tcaggctccg agggccgcgt ctgcattggg gaggcgcagc gttggggatt ccccactccc 120 acgagtttca cttcttctcc caacctatgt cgggtccttc ttccaggata ctcgtgacgc 180 gtccccattt cccactccca ttgggtgtcg ggtgtctaga gaagccaatc agtgtcgccg 240 gggtcccagt tctaaagtcc ccacgcaccc acccggactc agagtctcct cagacaccga 300 gatgcgggtc acggcacccc gaaccctcct cctgctgctc tggggggccc tggccctgac 360 cgagacctgg gccggtgagt gcgggtcggg agggaaatgg cctctgtggg gaggagcgag 420 gggaccgcag gcgggggcgc aggacccggg gagccgcgcc gggaggaggg tctggcgggt 480 ctcagcccct cctcgccccc aggctcccac tccatgaggt atttctacac cgccatgtcc 540 cggcccggcc gcggggagcc ccgcttcatc gcagtgggct acgtggacga cacgcagttc 600 gtgaggttcg acagcgacgc cgcgagtccg agagaggagc cgcgggcgcc gtggatagag 660 caggaggggc cggagtattg ggaccggaac acacagatct acaaggccca ggcacagact 720 gaccgagaga gcctgcggaa cctgcgcggc tactacaacc agagcgaggc cggtgagtga 780 ccccggcccg gggcgcaggt cacgactccc catcccccac gtacggcccg ggtcgccccg 840 agtctccggg tccgagatcc gcctccctga ggccgcggga cccgcccaga ccctcgaccg 900 gcgagagccc caggcgcgtt tacccggttt cattttcagt tgaggccaaa atccccgcgg 960 gttggtcggg gcggggcggg gctcggggga cggggctgac cgcggggccg gggccagggt 1020 ctcacacttg gcagacgatg tatggctgcg acctggggcc ggacgggcgc ctcctccgcg 1080 ggcataacca gttagcctac gacggcaagg attacatcgc cctgaacgag gacctgagct 1140 cctggaccgc ggcggacacc gcggctcaga tcacccagcg caagtgggag gcggcccgtg 1200 aggcggagca gctgagagcc tacctggagg gcacgtgcgt ggagtggctc cgcagatacc 1260 tggagaacgg gaaggagacg ctgcagcgcg cgggtaccag gggcagtggg gagccttccc 1320 catctcctat aggtcgccgg ggatggcctc ccacgagaag aggaggaaaa tgggatcagc 1380 gctagaatgt cgccctccct tgaatggaga atggcatgag ttttcctgag tttcctctga 1440 gggccccctc ttctctctag gacaattaag ggatgacgtc tctgaggaaa tggaggggaa 1500 gacagtccct agaatactga tcaggggtcc tctttgaccc ctgcagcagc cttgggaacc 1560 gtgacttttc ctctcaggcc ttgttctctg cctcacactc agtgtgtttg gggctctgat 1620 tccagcactt ctgagtcact ttacctccac tcagatcagg agcagaagtc cctgttcccc 1680 gctcagagac tcgaactttc caatgaatag gagattatcc caggtgcctg cgtccaggct 1740 ggtgtctggg ttctgtgccc cttccccacc ccaggtgtcc tgtccattct caggctggtc 1800 acatgggtgg tcctagggtg tcctatgaga gatgcaaagc gcctgaattt tctgactctt 1860 cccatcagac cccccaaaga cacacgtgac ccaccacccc atctctgacc atgaggccac 1920 cctgaggtgc tgggccctgg gcttctaccc tgcggagatc acactgacct ggcagcggga 1980 tggcgaggac caaactcagg acactgagct tgtggagacc agaccagcag gagatagaac 2040 cttccagaag tgggcagctg tggtggtgcc ttctggagaa gagcagagat acacatgcca 2100 tgtacagcat gaggggctgc cgaagcccct caccctgaga tggggtaagg agggggatga 2160 ggggtcatat ctcttctcag ggaaagcagg agcccttctg gagcccttca gcagggtcag 2220 ggcccctcgt cttcccctcc tttcccagag ccatcttccc agtccaccat ccccatcgtg 2280 ggcattgttg ctggcctggc tgtcctagca gttgtggtca tcggagctgt ggtcgctact 2340 gtgatgtgta ggaggaagag ctcaggtagg gaaggggtga ggggtggggt ctgggttttc 2400 ttgtcccact gggggtttca agccccaggt agaagtgttc cctgcctcat tactgggaag 2460 cagcatccac acaggggcta atgcagcctg ggaccctgtg tgccagcact tactcttttg 2520 tgcagcacat gtgacaatga aggacggatg tatcaccttg atggttgtgg tgttggggtc 2580 ctgatttcag cattcatgag tcaggggaag gtccctgcta aggacagacc ttaggagggc 2640 agttggtcca ggacccacac ttgctttcct cgtgtttcct gatcctgcct tgggtctgta 2700 gtcatacttc tggaaattcc ttttgggtcc aagacgagga ggttcctcta agatctcatg 2760 gccctgcttc ctcccagtcc cctcacagna cattttcttc ccacaggtgg aaaaggaggg 2820 agctactctc aggctgcgtg taagtggtgg gggtgggagt gtggaggagc tcacccaccc 2880 cataattcct cctgtcccac gtctcctgcg ggctctgacc aggtcctgtt tttgttctac 2940 tccagccagc gacagtgccc agggctctga tgtgtctctc acagcttgaa aaggtgagat 3000 tcttggggtc tagagtgggc gggggggggt ggggtgggga gggggcagag gggaaaggcc 3060 tgggtaatgg agattctttg attgggatgt ttcgcgtgtg tggtgggctg tttagagtgt 3120 catcacttac catgactaac cagaatttgt tcatgactgt tgttttctgt agcctgagac 3180 agctgtcttg tgagggactg agatgcagga tttcttcact cctccccttt gtgacttcaa 3240 gagcctctgg catctctttc tgcaaaggca cctgaatgtg tctgcgtccc tgttagcata 3300 atgtgaggag gtggagagac agcccacccc cgtgtccact gtgacccctg ttcgcatgct 3360 gacctgtgtt tcctccccag aagcttgcgg aagggcgaat tccagcacac tggcggccgt 3420 tactagtgga tccgagctcg gtaccaagct tgatgca 3457 // |
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