Dbfetch
ID AJ310509; SV 1; linear; genomic DNA; STD; HUM; 3457 BP.
XX
AC AJ310509;
XX
DT 17-MAR-2001 (Rel. 67, Created)
DT 17-JUN-2008 (Rel. 96, Last updated, Version 4)
XX
DE Homo sapiens HLA-B gene for MHC class I antigen, allele B*5501; exons 1-7
XX
KW B*5501 allele; HLA-B gene; human leukocyte antigen B;
KW major histocompatibility complex; MHC class I antigen.
XX
OS Homo sapiens (human)
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
XX
RN [1]
RP 1-3457
RA Cox S.T.;
RT ;
RL Submitted (14-FEB-2001) to the INSDC.
RL Cox S.T., Dept of HLA Sequencing, Anthony Nolan Research, The Royal Free
RL Hospital, Pond Street, Hampstead, London, NW3 2QG, UNITED KINGDOM.
XX
RN [2]
RA Cox S.T.;
RT "Confirmation of HLA-B*5501";
RL Unpublished.
XX
DR MD5; 57eb71fc7974928a693c2c10149c1e5f.
XX
FH Key Location/Qualifiers
FH
FT source 1..3457
FT /organism="Homo sapiens"
FT /chromosome="6p21.31"
FT /mol_type="genomic DNA"
FT /tissue_type="blood"
FT /db_xref="taxon:9606"
FT mRNA join(302..374,503..772,1018..1293,1869..2144,2249..2365,
FT 2807..2839,2946..2989)
FT /gene="HLA-B"
FT /note="B*5501"
FT /citation=[2]
FT CDS join(302..374,503..772,1018..1293,1869..2144,2249..2365,
FT 2807..2839,2946..2989)
FT /gene="HLA-B"
FT /product="HLA-B"
FT /function="antigen presentation"
FT /note="B*5501"
FT /db_xref="GOA:P30493"
FT /db_xref="HGNC:HGNC:4932"
FT /db_xref="IMGT/HLA:B*55:01:01"
FT /db_xref="InterPro:IPR001039"
FT /db_xref="InterPro:IPR003006"
FT /db_xref="InterPro:IPR003597"
FT /db_xref="InterPro:IPR007110"
FT /db_xref="InterPro:IPR010579"
FT /db_xref="InterPro:IPR011161"
FT /db_xref="InterPro:IPR011162"
FT /db_xref="InterPro:IPR013783"
FT /db_xref="InterPro:IPR036179"
FT /db_xref="InterPro:IPR037055"
FT /db_xref="UniProtKB/Swiss-Prot:P30493"
FT /citation=[2]
FT /protein_id="CAC34574.1"
FT /translation="MRVTAPRTLLLLLWGALALTETWAGSHSMRYFYTAMSRPGRGEPR
FT FIAVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRN
FT LRGYYNQSEAGSHTWQTMYGCDLGPDGRLLRGHNQLAYDGKDYIALNEDLSSWTAADTA
FT AQITQRKWEAAREAEQLRAYLEGTCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHE
FT ATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRY
FT TCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLAVVVIGAVVATVMCRRKSSGGK
FT GGSYSQAASSDSAQGSDVSLTA"
FT exon 302..374
FT /gene="HLA-B"
FT /number=1
FT /note="B*5501"
FT intron 375..502
FT /gene="HLA-B"
FT /number=1
FT /note="B*5501"
FT exon 503..772
FT /gene="HLA-B"
FT /number=2
FT /note="B*5501"
FT intron 773..1017
FT /gene="HLA-B"
FT /number=2
FT /note="B*5501"
FT exon 1018..1293
FT /gene="HLA-B"
FT /number=3
FT /note="B*5501"
FT intron 1294..1868
FT /gene="HLA-B"
FT /number=3
FT /note="B*5501"
FT exon 1869..2144
FT /gene="HLA-B"
FT /number=4
FT /note="B*5501"
FT intron 2145..2248
FT /gene="HLA-B"
FT /number=4
FT /note="B*5501"
FT exon 2249..2365
FT /gene="HLA-B"
FT /number=5
FT /note="B*5501"
FT intron 2366..2806
FT /gene="HLA-B"
FT /number=5
FT /note="B*5501"
FT exon 2807..2839
FT /gene="HLA-B"
FT /number=6
FT /note="B*5501"
FT intron 2840..2945
FT /gene="HLA-B"
FT /number=6
FT /note="B*5501"
FT exon 2946..2989
FT /gene="HLA-B"
FT /number=7
FT /note="B*5501"
XX
SQ Sequence 3457 BP; 643 A; 995 C; 1093 G; 725 T; 1 other;
tggtgtagga gaagagggat caggacgaag tcccatgtcc cggacggggc tctcagggtc 60
tcaggctccg agggccgcgt ctgcattggg gaggcgcagc gttggggatt ccccactccc 120
acgagtttca cttcttctcc caacctatgt cgggtccttc ttccaggata ctcgtgacgc 180
gtccccattt cccactccca ttgggtgtcg ggtgtctaga gaagccaatc agtgtcgccg 240
gggtcccagt tctaaagtcc ccacgcaccc acccggactc agagtctcct cagacaccga 300
gatgcgggtc acggcacccc gaaccctcct cctgctgctc tggggggccc tggccctgac 360
cgagacctgg gccggtgagt gcgggtcggg agggaaatgg cctctgtggg gaggagcgag 420
gggaccgcag gcgggggcgc aggacccggg gagccgcgcc gggaggaggg tctggcgggt 480
ctcagcccct cctcgccccc aggctcccac tccatgaggt atttctacac cgccatgtcc 540
cggcccggcc gcggggagcc ccgcttcatc gcagtgggct acgtggacga cacgcagttc 600
gtgaggttcg acagcgacgc cgcgagtccg agagaggagc cgcgggcgcc gtggatagag 660
caggaggggc cggagtattg ggaccggaac acacagatct acaaggccca ggcacagact 720
gaccgagaga gcctgcggaa cctgcgcggc tactacaacc agagcgaggc cggtgagtga 780
ccccggcccg gggcgcaggt cacgactccc catcccccac gtacggcccg ggtcgccccg 840
agtctccggg tccgagatcc gcctccctga ggccgcggga cccgcccaga ccctcgaccg 900
gcgagagccc caggcgcgtt tacccggttt cattttcagt tgaggccaaa atccccgcgg 960
gttggtcggg gcggggcggg gctcggggga cggggctgac cgcggggccg gggccagggt 1020
ctcacacttg gcagacgatg tatggctgcg acctggggcc ggacgggcgc ctcctccgcg 1080
ggcataacca gttagcctac gacggcaagg attacatcgc cctgaacgag gacctgagct 1140
cctggaccgc ggcggacacc gcggctcaga tcacccagcg caagtgggag gcggcccgtg 1200
aggcggagca gctgagagcc tacctggagg gcacgtgcgt ggagtggctc cgcagatacc 1260
tggagaacgg gaaggagacg ctgcagcgcg cgggtaccag gggcagtggg gagccttccc 1320
catctcctat aggtcgccgg ggatggcctc ccacgagaag aggaggaaaa tgggatcagc 1380
gctagaatgt cgccctccct tgaatggaga atggcatgag ttttcctgag tttcctctga 1440
gggccccctc ttctctctag gacaattaag ggatgacgtc tctgaggaaa tggaggggaa 1500
gacagtccct agaatactga tcaggggtcc tctttgaccc ctgcagcagc cttgggaacc 1560
gtgacttttc ctctcaggcc ttgttctctg cctcacactc agtgtgtttg gggctctgat 1620
tccagcactt ctgagtcact ttacctccac tcagatcagg agcagaagtc cctgttcccc 1680
gctcagagac tcgaactttc caatgaatag gagattatcc caggtgcctg cgtccaggct 1740
ggtgtctggg ttctgtgccc cttccccacc ccaggtgtcc tgtccattct caggctggtc 1800
acatgggtgg tcctagggtg tcctatgaga gatgcaaagc gcctgaattt tctgactctt 1860
cccatcagac cccccaaaga cacacgtgac ccaccacccc atctctgacc atgaggccac 1920
cctgaggtgc tgggccctgg gcttctaccc tgcggagatc acactgacct ggcagcggga 1980
tggcgaggac caaactcagg acactgagct tgtggagacc agaccagcag gagatagaac 2040
cttccagaag tgggcagctg tggtggtgcc ttctggagaa gagcagagat acacatgcca 2100
tgtacagcat gaggggctgc cgaagcccct caccctgaga tggggtaagg agggggatga 2160
ggggtcatat ctcttctcag ggaaagcagg agcccttctg gagcccttca gcagggtcag 2220
ggcccctcgt cttcccctcc tttcccagag ccatcttccc agtccaccat ccccatcgtg 2280
ggcattgttg ctggcctggc tgtcctagca gttgtggtca tcggagctgt ggtcgctact 2340
gtgatgtgta ggaggaagag ctcaggtagg gaaggggtga ggggtggggt ctgggttttc 2400
ttgtcccact gggggtttca agccccaggt agaagtgttc cctgcctcat tactgggaag 2460
cagcatccac acaggggcta atgcagcctg ggaccctgtg tgccagcact tactcttttg 2520
tgcagcacat gtgacaatga aggacggatg tatcaccttg atggttgtgg tgttggggtc 2580
ctgatttcag cattcatgag tcaggggaag gtccctgcta aggacagacc ttaggagggc 2640
agttggtcca ggacccacac ttgctttcct cgtgtttcct gatcctgcct tgggtctgta 2700
gtcatacttc tggaaattcc ttttgggtcc aagacgagga ggttcctcta agatctcatg 2760
gccctgcttc ctcccagtcc cctcacagna cattttcttc ccacaggtgg aaaaggaggg 2820
agctactctc aggctgcgtg taagtggtgg gggtgggagt gtggaggagc tcacccaccc 2880
cataattcct cctgtcccac gtctcctgcg ggctctgacc aggtcctgtt tttgttctac 2940
tccagccagc gacagtgccc agggctctga tgtgtctctc acagcttgaa aaggtgagat 3000
tcttggggtc tagagtgggc gggggggggt ggggtgggga gggggcagag gggaaaggcc 3060
tgggtaatgg agattctttg attgggatgt ttcgcgtgtg tggtgggctg tttagagtgt 3120
catcacttac catgactaac cagaatttgt tcatgactgt tgttttctgt agcctgagac 3180
agctgtcttg tgagggactg agatgcagga tttcttcact cctccccttt gtgacttcaa 3240
gagcctctgg catctctttc tgcaaaggca cctgaatgtg tctgcgtccc tgttagcata 3300
atgtgaggag gtggagagac agcccacccc cgtgtccact gtgacccctg ttcgcatgct 3360
gacctgtgtt tcctccccag aagcttgcgg aagggcgaat tccagcacac tggcggccgt 3420
tactagtgga tccgagctcg gtaccaagct tgatgca 3457
//
