Dbfetch

ID   AJ309047; SV 1; linear; genomic DNA; STD; HUM; 3039 BP.
XX
AC   AJ309047;
XX
DT   31-MAR-2001 (Rel. 67, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 4)
XX
DE   Homo sapiens HLA-B gene for MHC class I antigen, B*07021 allele, exons 1-7
XX
KW   HLA-B gene; HLA-B*07021 allele; human leucocyte antigen B;
KW   major histocompatibility complex; MHC class I antigen.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-3039
RA   Marsh S.G.E.;
RT   ;
RL   Submitted (29-MAR-2001) to the INSDC.
RL   Marsh S.G.E., HLA Informatics Group, Anthony Nolan Research Institute,
RL   Fleet Road, Hampstead, London, NW3 2QG, UNITED KINGDOM.
XX
RN   [2]
RA   Marsh S.G.E.;
RT   "Intron sequences of HLA Class I";
RL   Unpublished.
XX
DR   MD5; ae5394f6e059d59e5c5f2e481f0ae508.
DR   Ensembl-Gn; ENSG00000234745; homo_sapiens.
DR   Ensembl-Tr; ENST00000412585; homo_sapiens.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..3039
FT                   /organism="Homo sapiens"
FT                   /mol_type="genomic DNA"
FT                   /cell_line="JY"
FT                   /db_xref="taxon:9606"
FT   CDS             join(1..73,202..471,717..992,1567..1842,1936..2052,
FT                   2494..2526,2633..2676)
FT                   /gene="HLA-B"
FT                   /product="MHC class I antigen"
FT                   /function="antigen presenting molecule"
FT                   /note="B*07021 allele"
FT                   /db_xref="GOA:P01889"
FT                   /db_xref="HGNC:HGNC:4932"
FT                   /db_xref="IMGT/HLA:B*07:02:01"
FT                   /db_xref="InterPro:IPR001039"
FT                   /db_xref="InterPro:IPR003006"
FT                   /db_xref="InterPro:IPR003597"
FT                   /db_xref="InterPro:IPR007110"
FT                   /db_xref="InterPro:IPR010579"
FT                   /db_xref="InterPro:IPR011161"
FT                   /db_xref="InterPro:IPR011162"
FT                   /db_xref="InterPro:IPR013783"
FT                   /db_xref="PDB:3VCL"
FT                   /db_xref="PDB:4U1H"
FT                   /db_xref="PDB:4U1K"
FT                   /db_xref="PDB:5EO0"
FT                   /db_xref="PDB:5EO1"
FT                   /db_xref="UniProtKB/Swiss-Prot:P01889"
FT                   /protein_id="CAC35468.1"
FT                   /translation="MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPR
FT                   FISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRN
FT                   LRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTA
FT                   AQITQRKWEAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHE
FT                   ATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRY
FT                   TCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGK
FT                   GGSYSQAACSDSAQGSDVSLTA"
FT   exon            <1..73
FT                   /gene="HLA-B"
FT                   /number=1
FT                   /note="B*07021 allele"
FT   intron          74..201
FT                   /gene="HLA-B"
FT                   /number=1
FT                   /note="B*07021 allele"
FT   exon            202..471
FT                   /gene="HLA-B"
FT                   /number=2
FT                   /note="B*07021 allele"
FT   intron          472..716
FT                   /gene="HLA-B"
FT                   /number=2
FT                   /note="B*07021 allele"
FT   exon            717..992
FT                   /gene="HLA-B"
FT                   /number=3
FT                   /note="B*07021 allele"
FT   intron          993..1566
FT                   /gene="HLA-B"
FT                   /number=3
FT                   /note="B*07021 allele"
FT   exon            1567..1842
FT                   /gene="HLA-B"
FT                   /number=4
FT                   /note="B*07021 allele"
FT   intron          1843..1935
FT                   /gene="HLA-B"
FT                   /number=4
FT                   /note="B*07021 allele"
FT   exon            1936..2052
FT                   /gene="HLA-B"
FT                   /number=5
FT                   /note="B*07021 allele"
FT   intron          2053..2493
FT                   /gene="HLA-B"
FT                   /number=5
FT                   /note="B*07021 allele"
FT   exon            2494..2526
FT                   /gene="HLA-B"
FT                   /number=6
FT                   /note="B*07021 allele"
FT   intron          2527..2632
FT                   /gene="HLA-B"
FT                   /number=6
FT                   /note="B*07021 allele"
FT   exon            2633..2676
FT                   /gene="HLA-B"
FT                   /number=7
FT                   /note="B*07021 allele"
FT   3'UTR           2677..3039
FT                   /gene="HLA-B"
FT                   /note="B*07021 allele"
XX
SQ   Sequence 3039 BP; 563 A; 865 C; 973 G; 638 T; 0 other;
     atgctggtca tggcgccccg aaccgtcctc ctgctgctct cggcggccct ggccctgacc        60
     gagacctggg ccggtgagtg cgggtcggga gggaaatggc ctctgccggg aggagcgagg       120
     ggaccgcagg cgggggcgca ggacctgagg agccgcgccg ggaggagggt cgggcgggtc       180
     tcagcccctc ctcaccccca ggctcccact ccatgaggta tttctacacc tccgtgtccc       240
     ggcccggccg cggggagccc cgcttcatct cagtgggcta cgtggacgac acccagttcg       300
     tgaggttcga cagcgacgcc gcgagtccga gagaggagcc gcgggcgccg tggatagagc       360
     aggaggggcc ggagtattgg gaccggaaca cacagatcta caaggcccag gcacagactg       420
     accgagagag cctgcggaac ctgcgcggct actacaacca gagcgaggcc ggtgagtgac       480
     cccggcccgg ggcgcaggtc acgactcccc atcccccacg tacggcccgg gtcgccccga       540
     gtctccgggt ccgagatccg cctccctgag gccgcgggac ccgcccagac cctcgaccgg       600
     cgagagcccc aggcgcgttt acccggtttc attttcagtt gaggccaaaa tccccgcggg       660
     ttggtcgggg cggggcgggg ctcgggggac tgggctgacc gcggggccgg ggccagggtc       720
     tcacaccctc cagagcatgt acggctgcga cgtggggccg gacgggcgcc tcctccgcgg       780
     gcatgaccag tacgcctacg acggcaagga ttacatcgcc ctgaacgagg acctgcgctc       840
     ctggaccgcc gcggacacgg cggctcagat cacccagcgc aagtgggagg cggcccgtga       900
     ggcggagcag cggagagcct acctggaggg cgagtgcgtg gagtggctcc gcagatacct       960
     ggagaacggg aaggacaagc tggagcgcgc tggtaccagg ggcagtgggg agccttcccc      1020
     atctcctata ggtcgccggg gatggcctcc cacgagaaga ggaggaaaat gggatcagcg      1080
     ctagaatgtc gccctccgtt gaatggagaa tggcatgagt tttcctgagt ttcctctgag      1140
     ggccccctct tctctctaga caattaagga atgacgtctc tgaggaaatg gaggggaaga      1200
     cagtccctag aatactgatc aggggtcccc tttgacccct gcagcagcct tgggaaccgt      1260
     gacttttcct ctcaggcctt gttctctgcc tcacactcag tgtgtttggg gctctgattc      1320
     cagcacttct gagtcacttt acctccactc agatcaggag cagaagtccc tgttccccgc      1380
     tcagagactc gaactttcca atgaatagga gattatccca ggtgcctgcg tccaggctgg      1440
     tgtctgggtt ctgtgcccct tccccacccc aggtgtcctg tccattctca ggctggtcac      1500
     atgggtggtc ctagggtgtc ccatgaaaga tgcaaagcgc ctgaattttc tgactcttcc      1560
     catcagaccc cccaaagaca cacgtgaccc accaccccat ctctgaccat gaggccaccc      1620
     tgaggtgctg ggccctgggt ttctaccctg cggagatcac actgacctgg cagcgggatg      1680
     gcgaggacca aactcaggac actgagcttg tggagaccag accagcagga gatagaacct      1740
     tccagaagtg ggcagctgtg gtggtgcctt ctggagaaga gcagagatac acatgccatg      1800
     tacagcatga ggggctgccg aagcccctca ccctgagatg gggtaaggag ggggatgagg      1860
     ggtcatatct cttctcaggg aaagcaggag cccttcagca gggtcagggc ccctcatctt      1920
     cccctccttt cccagagccg tcttcccagt ccaccgtccc catcgtgggc attgttgctg      1980
     gcctggctgt cctagcagtt gtggtcatcg gagctgtggt cgctgctgtg atgtgtagga      2040
     ggaagagttc aggtagggaa ggggtgaggg gtggggtctg ggttttcttg tcccactggg      2100
     ggtttcaagc cccaggtaga agtgttccct gcctcattac tgggaagcag catgcacaca      2160
     ggggctaacg cagcctggga ccctgtgtgc cagcacttac tcttttgtgc agcacatgtg      2220
     acaatgaagg atggatgtat caccttgatg gttgtggtgt tggggtcctg attccagcat      2280
     tcatgagtca ggggaaggtc cctgctaagg acagacctta ggagggcagt tggtccagga      2340
     cccacacttg ctttcctcgt gtttcctgat cctgccctgg gtctgtagtc atacttctgg      2400
     aaattccttt tgggtccaag actaggaggt tcctctaaga tctcatggcc ctgcttcctc      2460
     ccagtgccct cacaggacat tttcttccca caggtggaaa aggagggagc tactctcagg      2520
     ctgcgtgtaa gtggtggggg tgggagtgtg gaggagctca cccaccccat aattcctcct      2580
     gtcccacgtc tcctgcgggc tctgaccagg tcctgttttt gttctactcc aggcagcgac      2640
     agtgcccagg gctctgatgt gtctctcaca gcttgaaaag gtgagattct tggggtctag      2700
     agtgggtggg gtggcgggtc tgggggtggg tggggcagag gggaaaggcc tgggtaatgg      2760
     ggattctttg attgggatgt ttcgcgtgtg tggtgggctg tttagagtgt catcgcttac      2820
     catgactaac cagaatttgt tcatgactgt tgttttctgt agcctgagac agctgtcttg      2880
     tgagggactg agatgcagga tttcttcacg cctccccttt gtgacttcaa gagcctctgg      2940
     catctctttc tgcaaaggca cctgaatgtg tctgcgtccc tgttagcata atgtgaggag      3000
     gtggagagac agcccaccct tgtgtccact gtgacccct                             3039
//