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EBI Dbfetch

ID   AJ250917; SV 1; linear; genomic DNA; STD; HUM; 1208 BP.
XX
AC   AJ250917;
XX
DT   17-NOV-1999 (Rel. 61, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 4)
XX
DE   Homo sapiens mRNA for human leucocyte antigen B (HLA-B gene, B*1501102N
DE   allele)
XX
KW   HLA-B gene; HLA-B*1501102N allele; human leucocyte antigen B;
KW   major histocompatibility complex; MHC class I antigen.
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-1208
RA   Curran M.M.;
RT   ;
RL   Submitted (25-OCT-1999) to the INSDC.
RL   Curran M.M., Histocompatibility and Immunogenetics lab, Belfast City
RL   Hospital, Blood transfusion building, Belfast City Hospital, Northern
RL   Ireland, Antrim, BT9 7TS, UNITED KINGDOM.
XX
RN   [2]
RX   DOI; 10.1034/j.1399-0039.1999.530304.x.
RX   PUBMED; 10203017.
RA   Curran M.D., Williams F., Little A.M., Rima B.K.;
RT   "Aberrant splicing of intron 1 creates a novel null HLA-B*1501 allele";
RL   Tissue Antigens 53(3):244-252(1999).
XX
DR   MD5; 1c5acd964349055939ac8654093dde0b.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1208
FT                   /organism="Homo sapiens"
FT                   /mol_type="genomic DNA"
FT                   /country="Ireland:Northern Ireland"
FT                   /cell_line="CL0012, ECACC"
FT                   /tissue_type="HLA-A*01, -A*03, -B*08, -B*1501102N"
FT                   /db_xref="taxon:9606"
FT   CDS             1..207
FT                   /gene="HLA-B"
FT                   /standard_name="MHC class I antigen"
FT                   /product="human leucocyte antigen B"
FT                   /note="B*1501102N allele"
FT                   /note="10bp deletion in intron 1 results in abberant
FT                   splicing and premature stop codon"
FT                   /db_xref="GOA:Q9UIM5"
FT                   /db_xref="IMGT/HLA:B*15:01:01:02N"
FT                   /db_xref="UniProtKB/TrEMBL:Q9UIM5"
FT                   /protein_id="CAB61432.1"
FT                   /translation="MRVTAPRTVLLLLSGALALTETWAGECGVGREMASVGRSEGTAGG
FT                   GAGPGEPRREEGRAPPRPQAPTP"
FT   exon            1..73
FT                   /gene="HLA-B"
FT                   /number=1
FT                   /note="allele HLA-B*1501102N"
FT   intron          74..192
FT                   /gene="HLA-B"
FT                   /number=1
FT                   /note="10bp deletion in intron 1 results in abberant
FT                   splicing and premature stop codon"
FT                   /experiment="experimental evidence, no additional details
FT                   recorded"
XX
SQ   Sequence 1208 BP; 237 A; 372 C; 419 G; 180 T; 0 other;
     atgcgggtca cggcgccccg aaccgtcctc ctgctgctct cgggagccct ggccctgacc        60
     gagacctggg ccggtgagtg cggggtcggc agggaaatgg cctctgtggg gaggagcgag       120
     gggaccgcag gcgggggcgc aggacccggg gagccgcgcc gggaggaggg tcgggcccct       180
     cctcgccccc aggctcccac tccatgaggt atttctacac cgccatgtcc cggcccggcc       240
     gcggggagcc ccgcttcatc gcagtgggct acgtggacga cacccagttc gtgaggttcg       300
     acagcgacgc cgcgagtccg aggatggcgc cccgggcgcc atggatagag caggaggggc       360
     cggagtattg ggaccgggag acacagatct ccaagaccaa cacacagact taccgagaga       420
     gcctgcggaa cctgcgcggc tactacaacc agagcgaggc cgggtctcac accctccaga       480
     ggatgtacgg ctgcgacgtg gggccggacg ggcgcctcct ccgcgggcat gaccagtccg       540
     cctacgacgg caaggattac atcgccctga acgaggacct gagctcctgg accgcggcgg       600
     acacggcggc tcagatcacc cagcgcaagt gggaggcggc ccgtgaggcg gagcagtgga       660
     gagcctacct ggagggcctg tgcgtggagt ggctccgcag atacctggag aacgggaagg       720
     agacgctgca gcgcgcggac cccccaaaga cacatgtgac ccaccacccc atctctgacc       780
     atgaggccac cctgaggtgc tgggccctgg gcttctaccc tgcggagatc acactgacct       840
     ggcagcggga tggcgaggac caaactcagg acaccgagct tgtggagacc agaccagcag       900
     gagatagaac cttccagaag tgggcagctg tggtggtgcc ttctggagaa gagcagagat       960
     acacatgcca tgtacagcat gaggggctgc cgaagcccct caccctgaga tgggagccat      1020
     cttcccagtc caccatcccc atcgtgggca ttgttgctgg cctggctgtc ctagcagttg      1080
     tggtcatcgg agctgtggtc gctactgtga tgtgtaggag gaagagctca ggtggaaaag      1140
     gagggagcta ctctcaggct gcgtccagcg acagtgccca gggctctgat gtgtctctca      1200
     cagcttga                                                               1208
//


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