Dbfetch
ID AF523296; SV 1; linear; genomic DNA; STD; HUM; 6993 BP. XX AC AF523296; XX DT 03-JUL-2002 (Rel. 72, Created) DT 17-JUN-2008 (Rel. 96, Last updated, Version 4) XX DE Homo sapiens clone 435 MHC class Ib antigen (HLA-F) gene, HLA-F*0101 DE allele, complete cds. XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RP 1-6993 RX DOI; 10.1007/s00251-005-0076-z. RX PUBMED; 16570139. RA Pyo C.W., Williams L.M., Moore Y., Hyodo H., Li S.S., Zhao L.P., RA Sageshima N., Ishitani A., Geraghty D.E.; RT "HLA-E, HLA-F, and HLA-G polymorphism: genomic sequence defines haplotype RT structure and variation spanning the nonclassical class I genes"; RL Immunogenetics 58(4):241-251(2006). XX RN [2] RP 1-6993 RA Ishitani A., Miki A., Williams L.M., Moore Y., Geraghty D.E.; RT ; RL Submitted (21-JUN-2002) to the INSDC. RL Clinical Division, Fred Hutchinson Cancer Research Center, 1100 Fairview RL Ave. N., D4-100, Seattle, WA 98109-1024, USA XX DR MD5; b1a0e4e901b11cdd9504b291ca566537. DR Ensembl-Gn; ENSG00000137403; homo_sapiens. DR Ensembl-Gn; ENSG00000204642; homo_sapiens. DR Ensembl-Gn; ENSG00000206509; homo_sapiens. DR Ensembl-Gn; ENSG00000229698; homo_sapiens. DR Ensembl-Gn; ENSG00000235220; homo_sapiens. DR Ensembl-Gn; ENSG00000237508; homo_sapiens. DR Ensembl-Tr; ENST00000259951; homo_sapiens. DR Ensembl-Tr; ENST00000334668; homo_sapiens. DR Ensembl-Tr; ENST00000359076; homo_sapiens. DR Ensembl-Tr; ENST00000376848; homo_sapiens. DR Ensembl-Tr; ENST00000376861; homo_sapiens. DR Ensembl-Tr; ENST00000383515; homo_sapiens. DR Ensembl-Tr; ENST00000420067; homo_sapiens. DR Ensembl-Tr; ENST00000434407; homo_sapiens. DR Ensembl-Tr; ENST00000440590; homo_sapiens. DR IMGT/HLA; HLA-F*01:01:01:12; HLA02278. XX FH Key Location/Qualifiers FH FT source 1..6993 FT /organism="Homo sapiens" FT /chromosome="6" FT /mol_type="genomic DNA" FT /clone="435" FT /db_xref="taxon:9606" FT gap 997..1364 FT /estimated_length=368 FT gene <1943..>4886 FT /gene="HLA-F" FT /allele="HLA-F*0101" FT mRNA join(<1943..2006,2137..2406,2652..2927,3510..3785, FT 3926..4042,4490..4522,4882..>4886) FT /gene="HLA-F" FT /allele="HLA-F*0101" FT /product="MHC class Ib antigen" FT CDS join(1943..2006,2137..2406,2652..2927,3510..3785, FT 3926..4042,4490..4522,4882..4886) FT /codon_start=1 FT /gene="HLA-F" FT /allele="HLA-F*0101" FT /product="MHC class Ib antigen" FT /db_xref="GOA:P30511" FT /db_xref="HGNC:HGNC:4963" FT /db_xref="InterPro:IPR001039" FT /db_xref="InterPro:IPR003006" FT /db_xref="InterPro:IPR003597" FT /db_xref="InterPro:IPR007110" FT /db_xref="InterPro:IPR011161" FT /db_xref="InterPro:IPR011162" FT /db_xref="InterPro:IPR013783" FT /db_xref="InterPro:IPR036179" FT /db_xref="InterPro:IPR037055" FT /db_xref="PDB:5IUE" FT /db_xref="PDB:5KNM" FT /db_xref="UniProtKB/Swiss-Prot:P30511" FT /protein_id="AAM74991.1" FT /translation="MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIA FT VEYVDDTQFLRFDSDAAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLR FT RYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQI FT TQRFYEAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATL FT RCWALGFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCH FT VQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGS FT YSQAAV" XX SQ Sequence 6993 BP; 1554 A; 1671 C; 1783 G; 1617 T; 368 other; ggtaatggaa cagtgctaga gccactattc aggagtgaca gagtggtggg gactaaggga 60 agaggagggc ctgagggatg agagggacgg agggaagggc tggagaagca ggaggtgagg 120 agaaggagca gagggacaga atttgaaagc agcagaattc ttagctttaa acacattgtt 180 ttataaattt ttaaacacat tgttttataa atttttaata catccatcta cagagcctag 240 cagggtgttc cttgcatttg gcctttaaca ccttatgtgg gactgcctaa aaattaattg 300 ctttttctgc tttttttcag gtttaaaaaa atactaagtg ttccaataaa acatgcacac 360 cacttagatg cggatacttc ctaaaaacag gaagtgcatg agcactggtg aggggcattg 420 tgactgcgtt gaacacttgc aactttgagg tgaatgaatg tattggctcc tggttgcaat 480 atacaatcac acgttgtgct actttgtatt gtcaggagat gtcctggact cccacagaaa 540 ctcagggcta tggaatgaag gtaattttag aatacaacaa gagtcacaga tacatagtct 600 gggaaagcaa aacttaggag ctctgagagt tgtacaactg taatgcattt agacacattt 660 atatatcaag gggccaaagt aacagttttt acacataaga ttcctgattg gtcgggcgcg 720 gtggctcatg cctgtaatcg cagcactttg ggaggccgag gcgggaggat cacgaggtca 780 ggagatcgag accatcctgg ctaacacggt gaaacccgtc tctacaaaaa aattagccgg 840 gcgtggtggc gggcatctgt agtctcagct actcgggagg ctgaagcaga agaatggcgt 900 gaacccggga cgcagagctt gcagtgagcc gagatcgcgc cactgcactc cagcctgggc 960 ggcagagaga gactccgtct caaaaaaaaa aaaaaannnn nnnnnnnnnn nnnnnnnnnn 1020 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1080 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1140 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1200 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1260 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1320 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnngaagaa gaggaagaag 1380 aagaaactgt ctctacacct tcattctcag gacaagttca ttgtctggca ccaagctcct 1440 tggggtgaat tttcttccaa aagagtccgg ggagtccagg tatggaatgg gaggcagaaa 1500 gttcaatcaa gggactggga tttcggaatg aataatgaag ggagatggac tgggtccatg 1560 ccgaaggttt ctccctggtt tctcagcccc cgggcgaaga ctcagggaga cattgagaca 1620 caccctgcac aggaggggga gggggagggg gagggcaaag tcccagggcc ccaggagtgg 1680 ctctcaaggg ctcaggcccc gaggcggtgt ctggggttgg gaggctcagt attgagaatt 1740 ccccatctcc ccagagtttc tctttctctc ccaacccgtg tcaggtcctt cttcctggat 1800 actcataacg cggccccatt tctcactccc attgggcgtc gcgtttctag agaagccaat 1860 cagtgtcgcc gcagttccca ggttctaaag tcccacgcac cccgcgggac tcatattttt 1920 cccagacgcg gaggttgggg tcatggcgcc ccgaagcctc ctcctgctgc tctcaggggc 1980 cctggccctg accgatactt gggcgggtga gtgcggggtc cagagagaaa cggcctctgt 2040 ggggaggagt gaggggcccg cccggtgggg gcgcaggact cagggagccg cgcccggagg 2100 agggtctggc gggtctcagc ccctcctcgc ccccaggctc ccactccttg aggtatttca 2160 gcaccgctgt gtcgcggccc ggccgcgggg agccccgcta catcgccgtg gagtacgtag 2220 acgacacgca attcctgcgg ttcgacagcg acgccgcgat tccgaggatg gagccgcggg 2280 agccgtgggt ggagcaagag gggccgcagt attgggagtg gaccacaggg tacgccaagg 2340 ccaacgcaca gactgaccga gtggccctga ggaacctgct ccgccgctac aaccagagcg 2400 aggctggtga gtgaacccgg ccgggggcgc aggtcacgac caccccccat ccgccacgga 2460 ccgcccgggt ccctcagagt ctccggatcc gaaatctacc ccgaggcagc gggacccgcc 2520 cagaccctcc acccgggaga gtcccaggcg cctttaccca ggttcatttt cagtttaggc 2580 caaaatcccc gcgggttggg cggggagggg gcggggctag ctgggcgggg ctgactgcgg 2640 ggaccggcta gggtctcaca ccctccaggg aatgaatggc tgcgacatgg ggcccgacgg 2700 acgcctcctc cgcgggtatc accagcacgc gtacgacggc aaggattaca tctccctgaa 2760 cgaggacctg cgctcctgga ccgcggcgga caccgtggct cagatcaccc agcgcttcta 2820 tgaggcagag gaatatgcag aggagttcag gacctacctg gagggcgagt gcctggagtt 2880 gctccgcaga tacttggaga atgggaagga gacgctacag cgcgcaggta ccaggggcca 2940 tgggcgcctt ccctatctcc tgtagatctc ttgggatggc ctcgcacaag gttgggagga 3000 aagtgggccc aatgctagga tatcgccctc cctctagtcc tgagtaggaa gaatcttcct 3060 ggctttcgag atccggtacc agagagtgac tgtgagagtc cgccctgctc tctgggacaa 3120 ttaagggatg aaatctctga gggaatggag ggaagacagt ccctggaata ccgatccgcg 3180 gtcccctttg agccctccaa cagccttggg ccccgtgact tttctctcaa gttttgttct 3240 ctgcctcaca ctcaatgtgt ttggggctct gattccagtc cctcggcctc cacttaggtc 3300 agggccagaa gtccctgctc ccccctcaga gactcgaact ttccaaggaa taggagattt 3360 tcccaggtgt ctgtgtccag gctggtgtct gggttctgtg ctcccttccc caccccaggt 3420 gtcctgtcca ttctcaggtt ggtcacatgg gtgctgctgg ggtttcccat gaggagtgca 3480 aagtgcctga attttctgac tcttctcaga tcctccaaag gcacacgttg cccaccaccc 3540 catctctgac catgaggcca ccctgaggtg ctgggccctg ggcttctacc ctgcggagat 3600 cacgctgacc tggcagcggg atggggagga acagacccag gacacagagc ttgtggagac 3660 caggcctgca ggggatggaa ccttccagaa gtgggccgct gtggtggtgc cttctggaga 3720 ggaacagaga tacacatgcc atgtgcagca cgaggggctg ccccagcccc tcatcctgag 3780 atggggtaag gagggagatg ggtaaagagg ggaacgaggg gtcatgtctt ttctcaggga 3840 aagcaggagc ccttctggag ctcttcagca gggtcagggc tgaggcctgg agatcagggc 3900 ccctcacctt cccttccttt cccagagcag tctccccagc ccaccatccc catcgtgggc 3960 atcgttgctg gccttgttgt ccttggagct gtggtcactg gagctgtggt cgctgctgtg 4020 atgtggagga agaagagctc aggtaggaag gggtgaggag tggagtctga gttttcttgt 4080 cccactgggg gttgcaagcc ccaagtagaa gtgtgccctg cctcattact gggaagcacc 4140 atccacactc atgggtctac ccagcctggg ccctgtgtgc cagcacctac tcatttgtaa 4200 agctcctgtg aaaatgaagg acagattctt cacttcgatg attatggtgg tgatgggacc 4260 tgatcccagc agtcacaaat cacaggggaa ggtccctgct gatgacagac ctcaggaggg 4320 cagttggtcc aggacccaca tctgctttct tcatatttct tgatcctgcc ctggatctac 4380 agttacactt ttctggaaac ttctctggga tcaaagacta ggggtttgct ctaggacctt 4440 atggccctgc ctcctttctg gcctctcaca ggacattttc ttcccataga tagaaacaga 4500 gggagctact ctcaggctgc aggtaagatg aaggaggctg atccctgaga ttgttgggat 4560 attgtggtca ggagcctatg agggagctca cccaccccac agttcctcta gccacatctg 4620 tgggctctga ccaggtcctg tttttgttct accccaatca ctgacagtgc tcagggctct 4680 ggggtgtctc tcacagctaa taaaggtgac actccagggc aggggccctg atgtgagtgg 4740 ggtgttgggg gggaacagag gggactcagc tgtgctattg ggtttctttg acttggatgt 4800 cttgagcatg aaatgggcta tttagagtgt tacctctcac tgtgactgat acgaatttgt 4860 tcatgaatat tttctctata gtgtgagaca gcttccttgt gtgggactga gaagcaagat 4920 atcaatgtag cagaattgca cttgtgcctc acgaacatac ataaatttta aaaataaaga 4980 ataaaaatat atctttttat agatacaggt agatatgttt ttatagcatg cacgtaaatg 5040 tgtgtgtgtg tgtgtgtgaa gagaaagagt gaatagagag attaagattc ttttaatggt 5100 gaaaagatat acatatattt ggaactagcc agcttgactc agtttaggtg atcccaattt 5160 tggtggcaac aaccaaagca tcgtagtcag gagccagtcg aacatatgcc ttcctctctc 5220 catcagactg aatcagagtg ttgactttgg ccacatcaat gtcacaaact tcttcacagc 5280 ctgtttgatc tggtgcttgt tggctttaac atccacagtg aacacaagta ggctgttgtt 5340 ttctatcttc ttcacagcct actcagtggt cagcggaaac ttgatgataa catggtggtc 5400 aagcttattt ctcctggggg tgctcttcca aggatatttg ggctgcctcc ggagtcacag 5460 tgtcttgggc cgccggaagg tgggtgacat gtggatcttg ttttttttgt ggctgtggac 5520 atctttcaac actgccttct tggccttgca aagccttcgc tttggcttcg gctttaggag 5580 gggcaggagc ttccttcttc gttcttggca ccatcttatg aaaagggtcc agattaagat 5640 ttttgactga gtcattctaa agtaagttgc aagacccatg atactagacc actaaatact 5700 tcatcacaca cctcctaaga ataagaacca acattatcac accaaagaaa ataaataatt 5760 ccataatatt atttaaagtc cttttatgtt caaatatctc cacttctttc agtacatttt 5820 tgtacctatt ttttatagct tgttttctta aaatgtccac tcgttgcctt tggttatatt 5880 tctttaatta cctacaatct ataacaatca acccatcttt tttcttttag aatggcatta 5940 cctgtttcag agatgaggcc aaatacctgt ggaatcttct ccacactgaa tttatcatat 6000 tatttcccct gatgccttta acttttttcc tctaactgct atgcctccta aggacctatg 6060 tagctctggg ttaaacattt ggcagcaatg tttacaggag gagctgtgac cgcacattca 6120 tcacatcagg aggcacacaa agcctagggt taccaggact ctttctgacc ccatacagcc 6180 aaatttatcc tgacttcccc gagatgcaga accatgggct gggtgtttag tgggtatgag 6240 tgtgatattc tggcaatagg aggttctgcc actctcccca ttcctcacga gctttagttc 6300 cccataccct gaggttctga gctccagacc ttcaaccatc aggccaggcc cctccagacc 6360 tagactccct tcctgtcttc tccagcccca ctctgcttgt atctacttcc ggatcacttt 6420 ccctctacag gcccagctcc tgagtgtctc tacctctcaa acaagtattc tcatccagga 6480 gcaattttcc caccagagga cattagctat gtctggaaaa atgttttgtt gccatgactg 6540 gagtgaggag gaggtgctac cagcatcttg tggggaatga ccagggatgc tgaacatcct 6600 gcagtgcaca agtcagccca atcacccaca taacagataa ttatccagcc ccaataccaa 6660 gattgccaag ggtaaggagg cctgccagga ctttctctcc cttgagtaca agcttccttg 6720 aactgaggga caccctgaag gaaaagtgtg gtcccacccc agtcatctct cccttccctg 6780 gagctccatc tgtatgcctg tagtgcttag gcctgtaacc tggggtccag gaacccacct 6840 tcccatgaga ctgcatgcag aagtgatgat atgtgcacac atgacttcat tacagggcat 6900 tggatattga tattcatcag gtcagctggg gcccaagaca ctactcttct gccaacaggc 6960 cgcaatcctc tgcattagag agagggtaaa gat 6993 //