Dbfetch

ID   AF416455; SV 1; linear; genomic DNA; STD; HUM; 3363 BP.
XX
AC   AF416455;
XX
DT   10-OCT-2001 (Rel. 69, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 5)
XX
DE   Homo sapiens MHC class I antigen (HLA-A) gene, HLA-A*0253N allele, complete
DE   sequence.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-3363
RX   DOI; 10.1034/j.1399-0039.2002.590414.x.
RX   PUBMED; 12135435.
RA   Wu G.G., Cheng L.H., Deng Z.H., Wang L.X., Wei T.L., Yang C.S., Zhao T.M.;
RT   "Cloning and complete sequence of a novel HLA-A null allele, A*0253 N, with
RT   a termination codon generated by a C to G mutation in exon 2";
RL   Tissue Antigens 59(4):328-330(2002).
XX
RN   [2]
RP   1-3363
RA   Wu G.-G., Cheng L.-H., Deng Z.-H., Wang L.-X., Wei T.-L., Yang C.-S.,
RA   Zhao T.-M.;
RT   ;
RL   Submitted (03-SEP-2001) to the INSDC.
RL   Molecular and Cellular Immunogenetics Section, NIAID, National Institutes
RL   of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
XX
DR   MD5; 7dc881655df85fd4990bc35fe7b21310.
DR   IMGT/HLA; A*02:53N; HLA01534.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..3363
FT                   /organism="Homo sapiens"
FT                   /chromosome="6"
FT                   /map="6p21"
FT                   /mol_type="genomic DNA"
FT                   /clone="Yanli"
FT                   /cell_type="leukocyte"
FT                   /db_xref="taxon:9606"
FT   gene            <359..>3275
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*0253N"
FT   mRNA            join(<359..431,562..831,1073..1348,1949..2224,2324..2440,
FT                   2879..2911,3054..3101,3271..>3275)
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*0253N"
FT                   /product="MHC class I antigen"
FT   exon            <359..431
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*0253N"
FT                   /number=1
FT   exon            562..831
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*0253N"
FT                   /number=2
FT   variation       812
FT                   /gene="HLA-A"
FT                   /replace="c"
FT                   /note="results in premature termination"
FT   exon            1073..1348
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*0253N"
FT                   /number=3
FT   exon            1949..2224
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*0253N"
FT                   /number=4
FT   exon            2324..2440
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*0253N"
FT                   /number=5
FT   exon            2879..2911
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*0253N"
FT                   /number=6
FT   exon            3054..3101
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*0253N"
FT                   /number=7
FT   exon            3271..>3275
FT                   /gene="HLA-A"
FT                   /allele="HLA-A*0253N"
FT                   /number=8
XX
SQ   Sequence 3363 BP; 653 A; 960 C; 1035 G; 715 T; 0 other;
     tttctcagac agctcttggg ccaagactca gggagacatt gagacagagc gcttggcaca        60
     gaagcagagg ggtcagggcg aagtcccagg gccccaggcg tggctctcag ggtctcaggc       120
     cccgaaggcg gtgtatggat tggggagtcc cagccttggg gattccccaa ctccgcagtt       180
     tcttttctcc ctctcccaac ctatgtaggg tccttcttcc tggatactca cgacgcggac       240
     ccagttctca ctcccattgg gtgtcgggtt tccagagaag ccaatcagtg tcgtcgcggt       300
     cgcggttcta aagtccgcac gcacccaccg ggactcagat tctccccaga cgccgaggat       360
     ggccgtcatg gcgccccgaa ccctcgtcct gctactctcg ggggctctgg ccctgaccca       420
     gacctgggcg ggtgagtgcg gggtcgggag ggaaacggcc tctgtgggga gaagcaacgg       480
     gcccgcctgg cgggggcgca ggacccggga agccgcgccg ggaggagggt cgggcgggtc       540
     tcagccactc ctcgtcccca ggctctcact ccatgaggta tttcttcaca tccgtgtccc       600
     ggcccggccg cggggagccc cgcttcatcg cagtgggcta cgtggacgac acgcagttcg       660
     tgcggttcga cagcgacgcc gcgagccaga ggatggagcc gcgggcgccg tggatagagc       720
     aggagggtcc ggagtattgg gacggggaga cacggaaagt gaaggcccac tcacagactc       780
     accgagtgga cctggggacc ctgcgcggct agtacaacca gagcgaggcc ggtgagtgac       840
     cccggcccgg ggcgcaggtc acgacctctc atcccccacg gacgggccag gtcgcccaca       900
     gtctccgggt ccgagatccg ccccgaagcc gcgggacccc gagacccttg ccccgggaga       960
     ggcccaggcg cctttacccg gtttcatttt cagtttaggc caaaaatccc cccaggttgg      1020
     tcggggcggg gcggggctcg ggggaccggg ctgaccgcgg ggtccgggcc aggttctcac      1080
     accgtccaga ggatgtatgg ctgcgacgtg gggtcggact ggcgcttcct ccgcgggtac      1140
     caccagtacg cctacgacgg caaggattac atcgccctga aagaggacct gcgctcttgg      1200
     accgcggcgg acatggcagc tcagaccacc aagcacaagt gggaggcggc ccatgtggcg      1260
     gagcagttga gagcctacct ggagggcacg tgcgtggagt ggctccgcag atacctggag      1320
     aacgggaagg agacgctgca gcgcacgggt accaggggcc acggggcgcc tccctgatcg      1380
     cctgtagatc tcccgggctg gcctcccaca aggaggggag acaattggga ccaacactag      1440
     aatatcgccc tccctctggt cctgagggag aggaatcctc ctgggtttcc agatcctgta      1500
     ccagagagtg actctgaggt tccgccctgc tctctgacac aattaaggga taaaatctct      1560
     gaaggaatga cgggaagacg atccctcgaa tactgatgag tggttccctt tgacacacac      1620
     aggcagcagc cttgggcccg tgacttttcc tctcaggcct tgttctctgc ttcacactca      1680
     atgtgtgtgg gggtctgagt ccagcacttc tgagtccttc agcctccact caggtcagga      1740
     ccagaagtcg ctgttccctc ttcagggact agaattttcc acggaatagg agattatccc      1800
     aggtgcctgt gtccaggctg gtgtctgggt tctgtgctcc cttccccatc ccaggtgtcc      1860
     tgtccattct caagatagcc acatgtgtgc tggaggagtg tcccatgaca gatgcaaaat      1920
     gcctgaatga tctgactctt cctgacagac gcccccaaaa cgcatatgac tcaccacgct      1980
     gtctctgacc atgaagccac cctgaggtgc tgggccctga gcttctaccc tgcggagatc      2040
     acactgacct ggcagcggga tggggaggac cagacccagg acacggagct cgtggagacc      2100
     aggcctgcag gggatggaac cttccagaag tgggcggctg tggtggtgcc ttctggacag      2160
     gagcagagat acacctgcca tgtgcagcat gagggtttgc ccaagcccct caccctgaga      2220
     tggggtaagg agggagacgg gggtgtcatg tcttttaggg aaagcaggag cctctctgac      2280
     ctttagcagg gtcagggccc ctcaccttcc cctcttttcc cagagccgtc ttcccagccc      2340
     accatcccca tcgtgggcat cattgctggc ctggttctct ttggagctgt gatcactgga      2400
     gctgtggtcg ctgctgtgat gtggaggagg aagagctcag gtggggaagg ggtgaagggt      2460
     gggtctgaga tttcttgtct cactgagggt tccaagaccc aggtagaagt gtgccctgcc      2520
     tcgttactgg gaagcaccac ccacaattat gggcctaccc agcctgggcc ctgtgtgcca      2580
     gcacttactc ttttgtaaag cacctgttaa aatgaaggac agatttatca ccttgattac      2640
     agcggtgatg ggacctgatc ccagcagtca caagtcacag gggaaggtcc ctgaggacct      2700
     tcaggagggc ggttggtcca ggacccacac ctgctttctt catgtttcct gatcccgccc      2760
     tgggtctgca gtcacacatt tctggaaact tctctgaggt ccaagacttg gaggttcctc      2820
     taggacctta aggccctgac tcctttctgg tatctcacag gacattttct tcccacagat      2880
     agaaaaggag ggagctactc tcaggctgca agtaagtatg aaggaggctg atgcctgagg      2940
     tccttgggat attgtgtttg ggagcccatg ggggagctca cccaccccac aattcctcct      3000
     ctagccacat cttctgtggg atctgaccag gttctgtttt tgttctaccc caggcagtga      3060
     cagtgcccag ggctctgatg tgtctctcac agcttgtaaa ggtgagagcc tggagggcct      3120
     gatgtgtgtt gggtgttggg cggaacagtg gacacagctg tgctatgggg tttctttcca      3180
     ttggatgtat tgagcatgcg atgggctgtt taaagtgtga cccctcactg tgacagatac      3240
     gaatttgttc atgaatattt ttttctatag tgtgagacag ctgccttgtg tgggactgag      3300
     aggcaagagt tgttcctgcc cttccctttg tgacttgaag aaccctgact ttgtttctgc      3360
     aaa                                                                    3363
//