Dbfetch

ID   AF384095; SV 1; linear; genomic DNA; STD; HUM; 3190 BP.
XX
AC   AF384095;
XX
DT   12-JUL-2001 (Rel. 68, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 4)
XX
DE   Homo sapiens MHC class I antigen (HLA-B) gene, HLA-B*44021 null allele,
DE   complete sequence.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-3190
RX   DOI; 10.1111/j.1399-0039.2004.00134.x.
RX   PUBMED; 14705988.
RA   Dubois V., Tiercy J.M., Labonne M.P., Dormoy A., Gebuhrer L.;
RT   "A new HLA-B44 allele (B*44020102S) with a splicing mutation leading to a
RT   complete deletion of exon 5";
RL   Tissue Antigens 63(2):173-180(2004).
XX
RN   [2]
RP   1-3190
RA   Dubois V., Labonne M.P., Primard Y., Dormoy A., Assaqa A., Tiercy J.M.,
RA   Gebuhrer L.;
RT   "A new HLA-B44 null allele due to a mutation in intron 4 responsible for
RT   deletion of exon 5";
RL   Unpublished.
XX
RN   [3]
RP   1-3190
RA   Gebuhrer L., Dubois V.;
RT   ;
RL   Submitted (22-MAY-2001) to the INSDC.
RL   Histocompatibility, EFS Rhone Alpes, 1 et 3 rue du Vercors, Lyon 69007,
RL   France
XX
DR   MD5; f07639727b18900e59448e0ed64162fc.
DR   IMGT/HLA; B*44:02:01:02S; HLA01606.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..3190
FT                   /organism="Homo sapiens"
FT                   /chromosome="6"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:9606"
FT   gene            1..3190
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*44021 null"
FT   mRNA            join(1..395,525..794,1038..1313,1889..2164,2816..2848,
FT                   2955..3002,3185..3190)
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*44021 null"
FT                   /product="MHC class I antigen"
FT   exon            1..395
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*44021 null"
FT                   /number=1
FT   exon            525..794
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*44021 null"
FT                   /number=2
FT   exon            1038..1313
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*44021 null"
FT                   /number=3
FT   exon            1889..2164
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*44021 null"
FT                   /number=4
FT   variation       2256
FT                   /gene="HLA-B"
FT                   /replace="g"
FT                   /note="results in incorrect splicing and elimination of
FT                   exon 5"
FT   exon            2258..2374
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*44021 null"
FT                   /number=5
FT   exon            2816..2848
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*44021 null"
FT                   /number=6
FT   exon            2955..3002
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*44021 null"
FT                   /number=7
FT   exon            3185..3190
FT                   /gene="HLA-B"
FT                   /allele="HLA-B*44021 null"
FT                   /number=8
XX
SQ   Sequence 3190 BP; 594 A; 920 C; 1025 G; 651 T; 0 other;
     cagacagtgt gacaaagagg ctggtgtagg agaagaggga tcaggacgaa gtcccaggtc        60
     ccggacgggg ctctcagggt ctcaggctcc gagggccgcg tctgcaatgg ggaggcgcag       120
     cgttggggat tccccactcc cacgagtttc acttcttctc ccaacctatg tcgggtcctt       180
     cttccaggat actcgtgacg cgtccccatt tcccactccc attgggtgtc gggtgtctag       240
     agaagccaat cagtgtcgcc ggggtcccag ttctaaagtc cccacgcacc cacccggact       300
     cagaatctcc tcagacgccg agatgcgggt cacggcgccc cgaaccctcc tcctgctgct       360
     ctggggggca gtggccctga ccgagacctg ggccggtgag tgcggggtcg ggagggaaat       420
     ggcctctgtg gggaggagag aggggaccgc aggcgggggc gcaggacccg gggagccgcg       480
     ccgggaggag ggtcgggcgg gtctcagccc ctcctcgccc ccaggctccc actccatgag       540
     gtatttctac accgccatgt cccggcccgg ccgcggggag ccccgcttca tcaccgtggg       600
     ctacgtggac gacacgctgt tcgtgaggtt cgacagcgac gccacgagtc cgaggaagga       660
     gccgcgggcg ccatggatag agcaggaggg gccggagtat tgggaccggg agacacagat       720
     ctccaagacc aacacacaga cttaccgaga gaacctgcgc accgcgctcc gctactacaa       780
     ccagagcgag gccggtgagt gaccccggcc cggggcgcag gtcacgactc cccatccccc       840
     acgtacggcc cgggtcgccc cgagtctccg ggtccgagat ccgcccccga ggccgcggga       900
     cccgcccaga ccctcgaccg gcgagagccc caggcgcgtt tacccggttt cattttcagt       960
     tgaggccaaa atccccgcgg gttggtcggg gcggggcggg gctcggggga cggggctgac      1020
     cgcggggccg gggccagggt ctcacatcat ccagaggatg tacggctgcg acgtggggcc      1080
     ggacgggcgc ctcctccgcg ggtatgacca ggacgcctac gacggcaagg attacatcgc      1140
     cctgaacgag gacctgagct cctggaccgc ggcggacacc gcggctcaga tcacccagcg      1200
     caagtgggag gcggcccgtg tggcggagca ggacagagcc tacctggagg gcctgtgcgt      1260
     ggagtcgctc cgcagatacc tggagaacgg gaaggagacg ctgcagcgcg cgggtaccag      1320
     gggcagtggg gagccttccc catctcctat aggtcgccgg ggatggcctc ccacgagaag      1380
     aggaggaaaa tgggatcagc gctagaatgt cgccctccct tgaatggaga atggcatgag      1440
     ttttcctgag tttcctctga gggccccctc ttctctctag gacaattaag ggatgacgtc      1500
     tctgaggaaa tggaggggaa gacagtccct agaatactga tcaggggtcc cctttgaccc      1560
     ctgcagcagc cttgggaacc gtgacttttc ctctcaggcc ttgttctctg cctcacactc      1620
     agtgtgtttg gggctctgat tccagcactt ctgagtcact ttacctccac tcagatcagg      1680
     agcagaagtc cctgttcccc gctcagagac tcgaactttc caatgaatag gagattatcc      1740
     caggtgcctg cgtccaggct ggtgtctggg ttctgtgccc cttccccacc ccaggtgtcc      1800
     tgtccattct caggctggtc acatgggtgg tcctagggtg tcccatgaga gatgcaaagc      1860
     gcctgaattt tctgactctt cccatcagac cccccaaaga cacatgtgac ccaccacccc      1920
     atctctgacc atgaggtcac cctgaggtgc tgggccctgg gcttctaccc tgcggagatc      1980
     acactgacct ggcagcggga tggcgaggac caaactcagg acaccgagct tgtggagacc      2040
     agaccagcag gagatagaac cttccagaag tgggcagctg tggtggtgcc ttctggagaa      2100
     gagcagagat acacatgcca tgtacagcat gaggggctgc cgaagcccct caccctgaga      2160
     tggggtaagg agggggatga ggggtcatat ctcttctcag ggaaagcagg agcccttcag      2220
     cagggtcagg gcccctcatc ttcccttcct ttcccggagc cgtcttccca gtccaccgtc      2280
     cccatcgtgg gcattgttgc tggcctggct gtcctagcag ttgtggtcat cggagctgtg      2340
     gtcgctgctg tgatgtgtag gaggaagagc tcaggtaggg aaggggtgag gggtggggtc      2400
     tgggttttct tgtcccactg ggggtttcaa gccccaggta gaagtgttcc ctgcctcatt      2460
     actgggaagc agcatccaca caggggctaa cgcagcctgg gaccctgtgt gccagcactt      2520
     actcttttgt gcagcacatg tgacaatgaa ggacggatgt atcaccttgg tggttgtggt      2580
     gttggggtcc tgattccagc attcatgagt caggggaagg tccctgctaa ggacagacct      2640
     taggagggca gttggtccag gacccacact tgctttcctc gtgtttcctg atcctgcctt      2700
     gggtctgtag tcatacttct ggaaattcct tttgggtcca agacgaggag gttcctctaa      2760
     gatctcatgg ccctgcttcc tcccagtccc ctcacagggc attttcttcc cacaggtgga      2820
     aaaggaggga gctactctca ggctgcgtgt aagtgatggg ggcgggagtg tggaggagct      2880
     cacccacccc ataattcctc ctgtcccacg tctcctgcgg gctctgacca ggtcctgttt      2940
     ttgttctact ccaggcagcg acagtgccca gggctctgat gtgtctctca cagcttgaaa      3000
     aggtgagatt cttggggtct agagtgggtg gggtggcagg tctgggggtg ggtggggcag      3060
     tggggaaagg cctgggtaat ggagattctt tgattgggat gtttcgcgtg tgtggtgggc      3120
     tgtttagagt gtcatcactt accatgacta accagaattt gttcatgact gttgttttct      3180
     gtagcctgag                                                             3190
//