ID AH010587; SV 2; linear; genomic DNA; STD; HUM; 2240 BP.
XX
AC AH010587; AF336079-AF336080;
XX
DT 30-JUN-2011 (Rel. 109, Created)
DT 30-JUN-2011 (Rel. 109, Last updated, Version 1)
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DE Homo sapiens MHC class I chain-related protein A (MICA) gene, MICA*019
DE allele, partial cds.
XX
KW .
XX
OS Homo sapiens (human)
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
XX
RN [1]
RP 1-2240
RX DOI; 10.1034/j.1399-0039.2001.057006520.x.
RX PUBMED; 11556982.
RA Obuchi N., Takahashi M., Nouchi T., Satoh M., Arimura T., Ueda K., Akai J.,
RA Ota M., Naruse T., Inoko H., Numano F., Kimura A.;
RT "Identification of MICA alleles with a long Leu-repeat in the transmembrane
RT region and no cytoplasmic tail due to a frameshift-deletion in exon 4";
RL Tissue Antigens 57(6):520-535(2001).
XX
RN [2]
RP 1-2240
RA Obuchi N., Kimura A.;
RT ;
RL Submitted (16-JAN-2001) to the INSDC.
RL 3rd Department of Internal Medicine, Tokyo and Medical and Dental
RL University, 1-3-45 Yushima, Bunkyou-Ku, Tokyo 113-8519, Japan
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DR MD5; 3a74880070706756ad01909e0eb1ed05.
DR Ensembl-Gn; ENSG00000183214; homo_sapiens.
DR Ensembl-Gn; ENSG00000235233; homo_sapiens.
DR Ensembl-Tr; ENST00000400325; homo_sapiens.
DR Ensembl-Tr; ENST00000418465; homo_sapiens.
DR Ensembl-Tr; ENST00000547609; homo_sapiens.
DR IMGT/LIGM; AH010587.
XX
CC On or before Jun 29, 2011 this sequence version replaced
CC gi:13469854, gi:13469855, gi:13469853.
XX
FH Key Location/Qualifiers
FH
FT source 1..2240
FT /organism="Homo sapiens"
FT /chromosome="6"
FT /map="6p21.3"
FT /mol_type="genomic DNA"
FT /cell_line="WT51"
FT /db_xref="taxon:9606"
FT gene <1..>2240
FT /gene="MICA"
FT /allele="MICA*019"
FT mRNA join(<1..255,530..817,1405..1683,1783..1917,2053..>2240)
FT /gene="MICA"
FT /allele="MICA*019"
FT /product="MHC class I chain-related protein A"
FT CDS join(<1..255,530..817,1405..1683,1783..1917,2053..2180)
FT /codon_start=3
FT /gene="MICA"
FT /allele="MICA*019"
FT /product="MHC class I chain-related protein A"
FT /note="similar to protein encoded by GenBank Accession
FT Number AF097405"
FT /db_xref="GOA:Q29983"
FT /db_xref="HGNC:HGNC:7090"
FT /db_xref="InterPro:IPR003597"
FT /db_xref="InterPro:IPR007110"
FT /db_xref="InterPro:IPR011161"
FT /db_xref="InterPro:IPR011162"
FT /db_xref="InterPro:IPR013783"
FT /db_xref="InterPro:IPR036179"
FT /db_xref="InterPro:IPR037055"
FT /db_xref="PDB:1B3J"
FT /db_xref="PDB:1HYR"
FT /db_xref="UniProtKB/Swiss-Prot:Q29983"
FT /protein_id="AAK27364.1"
FT /translation="PHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYDRQKCRAKPQ
FT GQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNSTR
FT SSQHFYYDGELFLSQNLETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADC
FT LQELRRYLESSVVLRRTVPPMVNVTRSEASEGNITVTCRASSFYPRNIILTWRQDGVSL
FT SHDTQQWGDVLPDGNGTYQTWVATRICRGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQS
FT HWQTFHVSAVAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHRDAT
FT QLGFQPLMSALGSTGSTEGA"
FT exon 1..255
FT /gene="MICA"
FT /allele="MICA*019"
FT /number=2
FT exon 530..817
FT /gene="MICA"
FT /allele="MICA*019"
FT /number=3
FT exon 1405..1683
FT /gene="MICA"
FT /allele="MICA*019"
FT /number=4
FT exon 1783..1917
FT /gene="MICA"
FT /allele="MICA*019"
FT /number=5
FT gap 1918..2017
FT /estimated_length=unknown
FT exon 2053..>2240
FT /gene="MICA"
FT /allele="MICA*019"
FT /number=6
FT 3'UTR 2181..>2240
FT /gene="MICA"
FT /allele="MICA*019"
XX
SQ Sequence 2240 BP; 480 A; 579 C; 632 G; 449 T; 100 other;
agccccacag tcttcgttat aacctcacgg tgctgtcctg ggatggatct gtgcagtcag 60
ggtttcttgc tgaggtacat ctggatggtc agcccttcct gcgctatgac aggcagaaat 120
gcagggcaaa gccccaggga cagtgggcag aagatgtcct gggaaataag acatgggaca 180
gagagaccag ggacttgaca gggaacggaa aggacctcag gatgaccctg gctcatatca 240
aggaccagaa agaaggtgag agtcggcagg ggcaagagtg actggagagg ccttttccag 300
aaaagttagg ggcagagagc agggacctgt ctcttcccac tggatctggc tcaggctggg 360
ggtgaggaat gggggtcagt ggaactcagc agggaggtga gccggcactc agcccacaca 420
gggaggcatg gaggagggcc agggaggcgt accccctggg ctgagttcct cacttgggtg 480
gaaaggtgat gggttcggga atggagaagt cactgctggg tgggggcagg cttgcattcc 540
ctccaggaga ttagggtctg tgagatccat gaagacaaca gcaccaggag ctcccagcat 600
ttctactacg atggggagct cttcctctcc caaaacctgg agactgagga atggacagtg 660
ccccagtcct ccagagctca gaccttggcc atgaacgtca ggaatttctt gaaggaagat 720
gccatgaaga ccaagacaca ctatcacgct atgcatgcag actgcctgca ggaactacgg 780
cgatatctag aatccagcgt agtcctgagg agaacaggta ccgacgctgg ccaggggctc 840
tcctctccct ccaattctgc tagagttgcc tcacctccca gatgtgtcca gggaaaccct 900
ccctgtgcta tggatgaagg catttcctgt tggcacatcg tgtcctgatt ttcctctatt 960
gttagagcca ctggataaag acagtgggtc agggactgga ccatccagtg ttgtaatcag 1020
ggcaagtaga ggaccctccg acagaatcct gagcctgtgg tgggtgtcag gtaggagagg 1080
aagccttcag ggccagggct gccccctctg cctcccagcc tgcccatcct ggagagttcc 1140
ctcctggccc cacaacccag gagtccaccc ctgacatccc cctcctcagc atcaatgtgg 1200
ggatcccaga gcctgaggcc acagtcccaa ggcccatcct cctgccagcc tggaagaact 1260
gggccccaga gtgaggacag acttgcaggt caggggtccc ggagggcttc agccagagtg 1320
agaacagtga agagaaacag ccctgttcct ctcccctcct tagaggggag cagggcttca 1380
ctggctctgc cctttcttct ccagtgcccc ccatggtgaa tgtcacccgc agcgaggcct 1440
cagagggcaa catcaccgtg acatgcaggg cttccagctt ctatccccgg aatatcatac 1500
tgacctggcg tcaggatggg gtatctttga gccacgacac ccagcagtgg ggggatgtcc 1560
tgcctgatgg gaatggaacc taccagacct gggtggccac caggatttgc cgaggagagg 1620
agcagaggtt cacctgctac atggaacaca gcgggaatca cagcactcac cctgtgccct 1680
ctggtgagcc tagggtgacc ctggagaggg tcaggccagg gtagggacag cagggatggc 1740
tgtggctctc tgcccagtgt ataacaagtc cctttttttc agggaaagtg ctggtgcttc 1800
agagtcattg gcagacattc catgtttctg ctgttgctgc tgctgctgct atttttgtta 1860
ttattatttt ctatgtccgt tgttgtaaga agaaaacatc agctgcagag ggtccagnnn 1920
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1980
nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnagt ggagcattta cccatttccc 2040
tcttttctcc agagctcgtg agcctgcagg tcctggatca acacccagtt gggacgagtg 2100
accacaggga tgccacacag ctcggatttc agcctctgat gtcagctctt gggtccactg 2160
gctccactga gggcgcctag actctacagc caggcggctg gaattgaatt ccctgcctgg 2220
atctcacaag cactttccct 2240
//
