ID AF305699; SV 2; linear; mRNA; STD; HUM; 1082 BP.
XX
AC AF305699;
XX
DT 08-NOV-2000 (Rel. 65, Created)
DT 07-OCT-2008 (Rel. 97, Last updated, Version 8)
XX
DE Homo sapiens MHC class I antigen precursor (HLA-A) mRNA, HLA-A*0214 allele,
DE partial cds.
XX
KW .
XX
OS Homo sapiens (human)
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
XX
RN [1]
RP 1-1082
RX DOI; 10.1007/s002510100299.
RX PUBMED; 11261925.
RA Luscher M.A., MacDonald K.S., Bwayo J.J., Plummer F.A., Barber B.H.;
RT "Sequence and peptide-binding motif for a variant of HLA-A*0214 (A*02142)
RT in an HIV-1-resistant individual from the Nairobi Sex Worker cohort";
RL Immunogenetics 53(1):10-14(2001).
XX
RN [2]
RC Erratum
RP 1-1082
RA Luscher M.A., Su J., MacDonald K.S., Bwayo J.J., Plummer F.A., Barber B.H.;
RT "Erratum: Sequence and peptide-binding motif for a variant of HLA-A*0214
RT (A*02142) in an HIV-1-resistant individual from the Nairobi Sex Worker
RT cohort";
RL Immunogenetics 53(8):717-717(2001).
XX
RN [3]
RP 1-1082
RA Luscher M.A., MacDonald K.S., Bwayo J.J., Plummer F.A., Barber B.H., Su J.;
RT ;
RL Submitted (14-SEP-2000) to the INSDC.
RL Division of Clinical Sciences, University of Toronto, 6366-1 King's College
RL Circle, Toronto, ON M5S 1A8, Canada
XX
DR MD5; 03ac570fb3b4db4f259d32e222f6e5fe.
DR H-InvDB; HIT000076784_03.4.
XX
CC On Aug 3, 2001 this sequence version replaced gi:11120554.
XX
FH Key Location/Qualifiers
FH
FT source 1..1082
FT /organism="Homo sapiens"
FT /chromosome="6"
FT /map="6p21.3"
FT /mol_type="mRNA"
FT /country="Kenya"
FT /sex="female"
FT /cell_line="ML1260"
FT /cell_type="EBV-transformed B cell"
FT /db_xref="taxon:9606"
FT CDS <1..>1082
FT /codon_start=2
FT /gene="HLA-A"
FT /product="MHC class I antigen precursor"
FT /note="human leukocyte antigen"
FT /db_xref="GOA:Q9GJ24"
FT /db_xref="H-InvDB:HIT000076784_02.4"
FT /db_xref="IMGT/HLA:A*02:14"
FT /db_xref="InterPro:IPR001039"
FT /db_xref="InterPro:IPR003006"
FT /db_xref="InterPro:IPR003597"
FT /db_xref="InterPro:IPR007110"
FT /db_xref="InterPro:IPR010579"
FT /db_xref="InterPro:IPR011161"
FT /db_xref="InterPro:IPR011162"
FT /db_xref="InterPro:IPR013783"
FT /db_xref="InterPro:IPR036179"
FT /db_xref="InterPro:IPR037055"
FT /db_xref="UniProtKB/TrEMBL:Q9GJ24"
FT /protein_id="AAG30922.2"
FT /translation="VMAPRTLVLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFI
FT AVGYVDDTQFVRFDSDAASRRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLR
FT GYYNQSEAGSHTLQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQ
FT TTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
FT LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTC
FT HVQHEGLPKPLTLRWEPSSQPTIPIVGIIAGLVLFGAVITGAVVAAVMWRRKSSDRKGG
FT SYSQAASSDSAQGSDVSLTA"
FT sig_peptide <1..67
FT /gene="HLA-A"
FT misc_feature 68..340
FT /gene="HLA-A"
FT /note="Region: alpha-1 domain"
FT misc_feature 338..616
FT /gene="HLA-A"
FT /note="Region: alpha-2 domain"
FT misc_feature 614..892
FT /gene="HLA-A"
FT /note="Region: alpha-3 domain"
FT misc_feature 890..1009
FT /gene="HLA-A"
FT /note="Region: transmembrane domain"
FT misc_feature 1007..1082
FT /gene="HLA-A"
FT /note="Region: intracellular domain"
XX
SQ Sequence 1082 BP; 214 A; 323 C; 363 G; 182 T; 0 other;
cgtcatggcg ccccgaaccc tcgtcctgct actctcgggg gctctggccc tgacccagac 60
ctgggcgggc tctcactcca tgaggtattt ctacacctcc gtgtcccggc ccggccgcgg 120
ggagccccgc ttcatcgcag tgggctacgt ggacgacacg cagttcgtgc ggttcgacag 180
cgacgccgcg agccggagga tggagccgcg ggcgccgtgg atagagcagg agggtccgga 240
gtattgggac ggggagacac ggaaagtgaa ggcccactca cagactcacc gagtggacct 300
ggggaccctg cgcggctact acaaccagag cgaggccggt tctcacaccc tccagaggat 360
gtatggctgc gacgtggggt cggactggcg cttcctgcgc gggtaccacc agtacgccta 420
cgacggcaag gattacatcg ccctgaaaga ggacctgcgc tcttggaccg cggcggacat 480
ggcagctcag accaccaagc acaagtggga ggcggcccat gtggcggagc agttgagagc 540
ctacctggag ggcacgtgcg tggagtggct ccgcagatac ctggagaacg ggaaggagac 600
gctgcagcgc acggacgccc ccaaaacgca tatgactcac cacgctgtct ctgaccatga 660
agccaccctg aggtgctggg ccctgagctt ctaccctgcg gagatcacac tgacctggca 720
gcgggatggg gaggaccaga cccaggacac ggagctcgtg gagaccaggc ctgcagggga 780
tggaaccttc cagaagtggg cggctgtggt ggtgccttct ggacaggagc agagatacac 840
ctgccatgtg cagcatgagg gtttgcccaa gcccctcacc ctgagatggg agccgtcttc 900
ccagcccacc atccccatcg tgggcatcat tgctggcctg gttctctttg gagctgtgat 960
cactggagct gtggtcgctg ctgtgatgtg gaggaggaag agctcagata gaaaaggagg 1020
gagctactct caggctgcaa gcagtgacag tgcccagggc tctgatgtgt ctctcacagc 1080
tt 1082
//
