Dbfetch

ID   AB088082; SV 1; linear; genomic DNA; STD; HUM; 6530 BP.
XX
AC   AB088082;
XX
DT   08-JAN-2003 (Rel. 74, Created)
DT   17-JUN-2008 (Rel. 96, Last updated, Version 5)
XX
DE   Homo sapiens HLA-F gene for major histocompatibility complex, class I, F,
DE   complete cds.
XX
KW   .
XX
OS   Homo sapiens (human)
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
XX
RN   [1]
RP   1-6530
RA   Shiina T.;
RT   ;
RL   Submitted (08-JUL-2002) to the INSDC.
RL   Takashi Shiina, Tokai University School of Medicine, Molecular Life Sciense
RL   2; Bohseidai, Isehara, Kanagawa 259-1193, Japan
RL   (E-mail:tshiina@is.icc.u-tokai.ac.jp, Tel:81-463-93-1121,
RL   Fax:81-463-94-8884)
XX
RN   [2]
RX   DOI; 10.1534/genetics.106.057034.
RX   PUBMED; 16702430.
RA   Shiina T., Ota M., Shimizu S., Katsuyama Y., Hashimoto N., Takasu M.,
RA   Anzai T., Kulski J.K., Kikkawa E., Naruse T., Kimura N., Yanagiya K.,
RA   Watanabe A., Hosomichi K., Kohara S., Iwamoto C., Umehara Y., Meyer A.,
RA   Wanner V., Sano K., Macquin C., Ikeo K., Tokunaga K., Gojobori T.,
RA   Inoko H., Bahram S.;
RT   "Rapid evolution of major histocompatibility complex class I genes in
RT   primates generates new disease alleles in humans via hitchhiking
RT   diversity";
RL   Genetics 173(3):1555-1570(2006).
XX
DR   MD5; 51fe65a0ad204c295032771699dac0be.
DR   EuropePMC; PMC1526686; 16702430.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..6530
FT                   /organism="Homo sapiens"
FT                   /chromosome="6"
FT                   /map="6p21.31"
FT                   /mol_type="genomic DNA"
FT                   /cell_line="LKT3"
FT                   /cell_type="B cell"
FT                   /db_xref="taxon:9606"
FT   CDS             join(1513..1576,1707..1976,2222..2497,3080..3355,
FT                   3496..3612,4060..4092,4228..4275,4452..4456)
FT                   /codon_start=1
FT                   /transl_table=1
FT                   /gene="HLA-F"
FT                   /product="major histocompatibility complex, class I, F"
FT                   /note="HLA class I molecule"
FT                   /db_xref="GOA:Q54A71"
FT                   /db_xref="IMGT/HLA:F*01:01:03:01"
FT                   /db_xref="InterPro:IPR001039"
FT                   /db_xref="InterPro:IPR003006"
FT                   /db_xref="InterPro:IPR003597"
FT                   /db_xref="InterPro:IPR007110"
FT                   /db_xref="InterPro:IPR010579"
FT                   /db_xref="InterPro:IPR011161"
FT                   /db_xref="InterPro:IPR011162"
FT                   /db_xref="InterPro:IPR013783"
FT                   /db_xref="UniProtKB/TrEMBL:Q54A71"
FT                   /protein_id="BAC54915.1"
FT                   /translation="MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIA
FT                   VEYVDDTQFLRFDSDAAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLR
FT                   RYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQI
FT                   TQRFYEAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATL
FT                   RCWALGFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCH
FT                   VQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGS
FT                   YSQAAVTDSAQGSGVSLTANKV"
FT   exon            1513..1576
FT                   /number=1
FT   exon            1707..1976
FT                   /number=2
FT   exon            2222..2497
FT                   /number=3
FT   exon            3080..3355
FT                   /number=4
FT   exon            3496..3612
FT                   /number=5
FT   exon            4060..4092
FT                   /number=6
FT   exon            4228..4275
FT                   /number=7
FT   exon            4452..4456
FT                   /number=8
XX
SQ   Sequence 6530 BP; 1583 A; 1634 C; 1774 G; 1539 T; 0 other;
     cctaaaaaca ggaagtgcat gagcactggt gaggggcatt gtgactgcgt tgaacacttg        60
     caactttgag gtgaatgaat gtattggctc ctggttgcaa tatacaatca cacgttgtgc       120
     tactttgtat tgtcaggaga tgtcctggac tcccacagaa actcagggct atggaatgaa       180
     ggtaatttta gaatacaaca agagtcacag atacatagtc tgggaaagca aaacttagga       240
     gctctgagag ttgtacaact gtaatgcatt tagacacatt tatatatcaa ggggccaaag       300
     taacagtttt tacacataag attcctgatt ggtcgggcgc ggtggctcat gcctgtaatc       360
     gcagcacttt gggaggccga ggcgggagga tcacgaggtc aggagatcga gaccatcctg       420
     gctaacacgg tgaaacccgt ctctacaaaa aaattagccg ggcgtggtgg cgggcatctg       480
     tagtctcagc tactcgggag gctgaagcag aagaatggcg tgaacccggg acgcagagct       540
     tgcagtgagc cgagatcgcg ccactgcact ccagcctggg cggcagagag agactccgtc       600
     tcaaaaaaaa aaaaaaaaaa aaaaaaaagg ttcctgataa ttcaggggtt accaagattc       660
     tactactcac tgcagctaat aaaaaaaaaa aaaagaaaga aagaaactgg tccctgtcct       720
     atttcatata ctcaggtaca acttttccag agaagaagag gaggggggcg gggaggagca       780
     ggaggaggag gaaagaagga ggagaaggag aaggagaagg agaaggagag aagaggaaga       840
     ggaagaagaa gaagaagaag aagaagaaga agaagaagaa gaagaagaag aagaagaaga       900
     agaagaagaa gaagaagaag aagaagaaga agaagaagaa aaggaagaag aagaaactgt       960
     ctctacacct tcattctcag gacaagttca ttgtctggca ccaagctcct tggggtgaat      1020
     tttcttccaa aagagtccgg ggagtccagg tatggaatgg gaggcagaaa gttcaatcaa      1080
     gggactggga tttcggaatg aataatgaag ggagatggac tgggtccatg ccgaaggttt      1140
     ctccctggtt tctcagcccc cgggcgaaga ctcagggaga cattgagaca caccctgcac      1200
     aggaggggga gggggagggg gagggcaaag tcccagggcc ccaggagtgg ctctcaaggg      1260
     ctcaggcccc gaggcggtgt ctggggttgg gaggctcagt attgagaatt ccccatctcc      1320
     ccagagtttc tctttctctc ccaacccgtg tcaggtcctt cttcctggat actcataacg      1380
     cggccccatt tctcactccc attgggcgtc gcgtttctag agaagccaat cagtgtcgcc      1440
     gcagttccca ggttctaaag tcccacgcac cccgcgggac tcatattttt cccagacgcg      1500
     gaggttgggg tcatggcgcc ccgaagcctc ctcctgctgc tctcaggggc cctggccctg      1560
     accgatactt gggcgggtga gtgcggggtc cagagagaaa cggcctctgt ggggaggagt      1620
     gaggggcccg cccggtgggg gcgcaggact cagggagccg cgcccggagg agggtctggc      1680
     gggtctcagc ccctcctcgc ccccaggctc ccactccttg aggtatttca gcaccgctgt      1740
     gtcgcggccc ggccgcgggg agccccgcta catcgccgtg gagtacgtag acgacacgca      1800
     attcctgcgg ttcgacagcg acgccgcgat tccgaggatg gagccgcggg agccgtgggt      1860
     ggagcaagag gggccgcagt attgggagtg gaccacaggg tacgccaagg ccaacgcaca      1920
     gactgaccga gtggccctga ggaacctgct ccgccgctac aaccagagcg aggctggtga      1980
     gtgaacccgg ccgggggcgc aggtcacgac caccccccat ccgccacgga ccgcccgggt      2040
     ccctcagagt ctccggatcc gaaatctacc ccgaggcagc gggacccgcc cagaccctcc      2100
     acccgggaga gtcccaggcg cctttaccca ggttcatttt cagtttaggc caaaatcccc      2160
     gcgggttggg cggggagggg gcggggctag ctgggcgggg ctgactgcgg ggaccggcta      2220
     gggtctcaca ccctccaggg aatgaatggc tgcgacatgg ggcccgacgg acgcctcctc      2280
     cgcgggtatc accagcacgc gtacgacggc aaggattaca tctccctgaa cgaggacctg      2340
     cgctcctgga ccgcggcgga caccgtggct cagatcaccc agcgcttcta tgaggcagag      2400
     gaatatgcag aggagttcag gacctacctg gagggcgagt gcctggagtt gctccgcaga      2460
     tacttggaga atgggaagga gacgctacag cgcgcaggta ccaggggcca tgggcgcctt      2520
     ccctatctcc tgtagatctc ttgggatggc ctcgcacaag gttgggagga aagtgggccc      2580
     aatgctagga tatcgccctc cctctagtcc tgagtaggaa gaatcttcct ggctttcgag      2640
     atccggtacc agagagtgac tgtgagagtc cgccctgctc tctgggacaa ttaagggatg      2700
     aaatctctga gggaatggag ggaagacagt ccctggaata ccgatccgcg gtcccctttg      2760
     agccctccaa cagccttggg ccccgtgact tttctctcaa gttttgttct ctgcctcaca      2820
     ctcaatgtgt ttggggctct gattccagtc cctcggcctc cacttaggtc agggccagaa      2880
     gtccctgctc ccccctcaga gactcgaact ttccaaggaa taggagattt tcccaggtgt      2940
     ctgtgtccag gctggtgtct gggttctgtg ctcccttccc caccccaggt gtcctgtcca      3000
     ttctcaggtt ggtcacatgg gtgctgctgg ggtttcccat gaggagtgca aagtgcctga      3060
     attttctgac tcttctcaga tcctccaaag gcacacgttg cccaccaccc catctctgac      3120
     catgaggcca ccctgaggtg ctgggccctg ggcttctacc ctgcggagat cacgctgacc      3180
     tggcagcggg atggggagga acagacccag gacacagagc ttgtggagac caggcctgca      3240
     ggggatggaa ccttccagaa gtgggccgct gtggtggtgc cttctggaga ggaacagaga      3300
     tacacatgcc atgtgcagca cgaggggctg ccccagcccc tcatcctgag atggggtaag      3360
     gagggagatg ggtaaagagg ggaacgaggg gtcatgtctt ttctcaggga aagcaggagc      3420
     ccttctggag ctcttcagca gggtcagggc tgaggcctgg agatcagggc ccctcacctt      3480
     cccttccttt cccagagcag tctccccagc ccaccatccc catcgtgggc atcgttgctg      3540
     gccttgttgt ccttggagct gtggtcactg gagctgtggt cgctgctgtg atgtggagga      3600
     agaagagctc aggtaggaag gggtgaggag tggagtctga gttttcttgt cccactgggg      3660
     gttgcaagcc ccaagtagaa gtgtgccctg cctcattact gggaagcacc atccacactc      3720
     atgggtctac ccagcctggg ccctgtgtgc cagcacctac tcatttgtaa agctcctgtg      3780
     aaaatgaagg acagattctt cacttcgatg attatggtgg tgatgggacc tgatcccagc      3840
     agtcacaaat cacaggggaa ggtccctgct gatgacagac ctcaggaggg cagttggtcc      3900
     aggacccaca tctgctttct tcatatttct tgatcctgcc ctggatctac agttacactt      3960
     ttctggaaac ttctctggga tcaaagacta ggggtttgct ctaggacctt atggccctgc      4020
     ctcctttctg gcctctcaca ggacattttc ttcccataga tagaaacaga gggagctact      4080
     ctcaggctgc aggtaagatg aaggaggctg atccctgaga ttgttgggat attgtggtca      4140
     ggagcctatg agggagctca cccaccccac agttcctcta gccacatctg tgggctctga      4200
     ccaggtcctg tttttgttct accccaatca ctgacagtgc tcagggctct ggggtgtctc      4260
     tcacagctaa taaaggtgac actccagggc aggggccctg atgtgagtgg ggtgttgggg      4320
     gggaacagag gggactcagc tgtgctattg ggtttctttg acttggatgt cttgagcatg      4380
     aaatgggcta tttagagtgt tacctctcac tgtgactgat acgaatttgt tcatgaatat      4440
     tttctctata gtgtgagaca gcttccttgt gtgggactga gaagcaagat atcaatgtag      4500
     cagaattgca cttgtgcctc acgaacatac ataaatttta aaaataaaga ataaaaatat      4560
     atctttttat agatacaggt agatatgttt ttatagcatg cacgtaaatg tgtgtgtgtg      4620
     tgtgtgtgaa gagaaagagt gaatagagag attaagattc ttttaatggt gaaaagatat      4680
     acatatattt ggaattagcc agcttgactc agtttaggtg atcccaattt tggtggcaac      4740
     aaccaaagca tcgtagtcag gagccagtcg aacatatgcc ttcctctctc catcagactg      4800
     aatcagagtg ttgactttgg ccacatcaat gtcacaaact tcttcacagc ctgtttgatc      4860
     tggtgcttgt tggctttaac atccacagtg aacacaagta ggctgttgtt ttctatcttc      4920
     ttcacagcct actcagtggt cagcggaaac ttgatgataa catggtggtc aagcttattt      4980
     ctcctggggg tgctcttcca aggatatttg ggctgcctcc ggagtcacag tgtcttgggc      5040
     cgccggaagg tgggtgacat gtggatcttg ttttttttgt ggctgtggac atctttcaac      5100
     actgccttct tggccttgca aagccttcgc tttggcttcg gctttaggag gggcaggagc      5160
     ttccttcttc gttcttggca ccatcttatg aaaagggtcc agattaagat ttttgactga      5220
     gtcattctaa agtaagttgc aagacccatg atactagacc actaaatact tcatcacaca      5280
     cctcctaaga ataagaacca acattatcac accaaagaaa ataaataatt ccataatatt      5340
     atttaaagtc cttttatgtt caaatatctc cacttctttc agtacatttt tgtacctatt      5400
     ttttatagct tgttttctta aaatgtccac tcgttgcctt tggttatatt tctttaatta      5460
     cctacaatct ataacaatca acccatcttt tttcttttag aatggcatta cctgtttcag      5520
     agatgaggcc aaatacctgt ggaatcttct ccacactgaa tttatcatat tatttcccct      5580
     gatgccttta acttttttcc tctaactgct atgcctccta aggacctatg tagctctggg      5640
     ttaaacattt ggcagcaatg tttacaggag gagctgtgac cgcacattca tcacatcagg      5700
     aggcacacaa agcctagggt taccaggact ctttctgacc ccatacagcc aaatttatcc      5760
     tgacttcccc gagatgcaga accatgggct gggtgtttag tgggtatgag tgtgatattc      5820
     tggcaatagg aggttctgcc actctcccca ttcctcacga gctttagttc cccataccct      5880
     gaggttctga gctccagacc ttcaaccatc aggccaggcc cctccagacc tagactccct      5940
     tcctgtcttc tccagcccca ctctgcttgt atctacttcc ggatcacttt ccctctacag      6000
     gcccagctcc tgagtgtctc tacctctcaa acaagtattc tcatccagga gcaattttcc      6060
     caccagagga cattagctat gtctggaaaa atgttttgtt gccatgactg gagtgaggag      6120
     gaggtgctac cagcatcttg tggggaatga ccagggatgc tgaacatcct gcagtgcaca      6180
     agtcagccca atcacccaca taacagataa ttatccagcc ccaataccaa gattgccaag      6240
     ggtaaggagg cctgccagga ctttctctcc cttgagtaca agcttccttg aactgaggga      6300
     caccctgaag gaaaagtgtg gtcccacccc agtcatctct cccttccctg gagctccatc      6360
     tgtatgcctg tagtgcttag gcctgtaacc tggggtccag gaacccacct tcccatgaga      6420
     ctgcatgcag aagtgatgat atgtgcacac atgacttcat tacagggcat tggatattga      6480
     tattcatcag gtcagctggg gcccaagaca ctactcttct gccaacaggc                 6530
//