Dbfetch
ID KIR00032; SV 3; standard; DNA; HUM; 9979 BP. XX AC KIR00032; XX SV KIR00032.3 XX DT 17-MAY-2002 (Rel. 1.0.0, Created, Version 1) DT 20-FEB-2009 (Rel. 2.1.0, Sequence Updated, Version 3) DT 16-DEC-2021 (Rel. 2.11.0, Current Release, Version 3) XX DE KIR2DL5B*004, Human Killer-cell Immunoglobulin-like Receptor XX KW Human Killer-cell Immunoglobulin-like Receptor; KIR2DL5B*004; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-KIR Release Version 2.11.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD Database, Distributed under the Creative Commons CC Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/licence.html for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-9979 RX PUBMED; 11086080. RA Vilches C, Gardiner CM, Parham P; RT "Gene structure and promoter variation of expressed and nonexpressed RT variants of the KIR2DL5 gene"; RL Journal of Immunology 165:6416-21(2000). XX RN [2] RP 1-9979 RX PUBMED; 17557377. RA Gomez-Lozano N, Trompeter HI, de Pablo R, Estefania E, Uhrberg M, Vilches RA C; RT "Epigenetic silencing of potentially functional KIR2DL5 alleles: RT Implications for the acquisition of KIR repertoires by NK cells."; RL European Journal of Immunology 37:1954-65(2007). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC KIR Nomenclature Committee. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; AF260138; AF260138.0. DR EMBL; AF260139; AF260139.0. DR EMBL; AF260140; AF260140.0. DR EMBL; AF260141; AF260141.0. DR EMBL; AM084878; AM084878.0. DR EMBL; EU450879; EU450879.0. DR EMBL; GU182357; GU182357.0. XX FH Key Location/Qualifiers FH FT source 1..9979 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="Black" FT /cell_line="CC-NK" FT /cell_line="RSH" FT /cell_line="UCLA342" FT CDS join(548..581,1335..1370,2133..2417,..,5759..5809, FT 8575..8679,9142..9194,9295..9564) FT /codon_start=1 FT /gene="KIR2DL5" FT /allele="KIR2DL5B*004" FT /product="KIR2DL5 Killer-cell Immunoglobulin-like FT Receptor" FT /translation="MSLMVVSMACVGFFLLQGAWTHEGGQDKPLLSAWPSTVVPRGGHV FT TLLCRSRLGFTIFSLYKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPI FT EWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHE FT PRLPAVPSVNGTFQADFPLGPATHGGTYTCFGSLHDSPYEWSDPSDPLLVSVTGNSSSS FT SSSPTEPSSKTGIRRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQEPAGDR FT TVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQRPKTPPTDTTMYMELPNAKPRSLS FT PAHKHHSQALRGSSRETTALSQNRVASSHVPAAGI" FT UTR 1..547 FT exon 548..581 FT /number="1" FT intron 582..1334 FT /number="1" FT exon 1335..1370 FT /number="2" FT intron 1371..2132 FT /number="2" FT exon 2133..2417 FT /number="3" FT intron 2418..3586 FT /number="3/4" FT intron 3587..5758 FT /number="4" FT exon 5759..5809 FT /number="5" FT intron 5810..8574 FT /number="5" FT exon 8575..8679 FT /number="6" FT intron 8680..9141 FT /number="6" FT exon 9142..9194 FT /number="7" FT intron 9195..9294 FT /number="7" FT exon 9295..9564 FT /number="8" FT UTR 9565..9979 SQ Sequence 9979 BP; 2496 A; 2340 C; 2535 G; 2608 T; 0 other; cttccctggg aatttaaatc attttagctg gttctgctgt aatactagaa atacaagcat 60 gaaaaattct aatggtttat tagtcacaat gactccgaaa acattaataa tacctattag 120 atactttgca tattacacag gaagaagagt ttgaatctca gataaaaaca aaaaaaatac 180 atgaaaagtc tttcatgtta gcacagattt taggcatctc gtgttcggat aaaaatacat 240 gaaaagtctt tcacgttagc acagatttta ggcatcttgt gttcgggagg ttggatctga 300 gacgtgttgt gagttggtca tagtgaagga cgtgaggtgc caattctagt gagaacaatt 360 tccaggaagc cgtgttccgc tcttgagcaa gcatccactg ggcctcatgc aaggtagaaa 420 gagcctgcgt acgtcaccct cccatgatgt agtcaacatg taagctgcat gggcagggcg 480 ccaaataaca tcctgtgcgc tgctgagctg agctggggcg cggctgcctg tctgcaccgg 540 cagcaccatg tcgctcatgg tcgtcagcat ggcgtgtgtt ggtgagtcct ggaaaggaat 600 agagggaggg agcgcgggga tggagatctg ggcccagagg tggagatata ggcctggagg 660 tggagttatg ggcctggagt ggagatctgg gcctggagtg gatatatggg cctggagatg 720 gagtgatggg cctagaagtg gagatctggg tctggagtgg agatatgggc ctggaggtgg 780 agatatgggc ctggagtgga gatctgggcc tggagtggag ataggaacct ggaggggaga 840 tatgagcctg gagtgaagat attggcctgg gatggagata tgggcctgga gtggagacat 900 gggcctggag gtggagatat gggcctggag gtggagacat gggcctagag gtggatatct 960 gggcctggag tggacatatg ggcctaggat ggagatatgg gcctgggtgt ggagatatgg 1020 gcttggggtg gagatatggg cctggattgg agatatgggt ctagggtgga aatattggcc 1080 tggagtggag atatgggcct ggagtggaga tatgggcttg gggtggggat aggggcctgg 1140 ggtgcggata tgggcctgca ggctgggtct ctacacagcc gacagccctg ttcttgggtg 1200 caggctggca ctgagggtga gtttcccttc agcccagcaa gggcctggct accaagactc 1260 acagcccagt gggggcagca agggagtcct ggtttgcctg cagatggatg gtccatcatg 1320 atctttcttt ccagggttct tcttgctgca gggggcctgg acacatgagg gtgagtcctt 1380 ctccaaacct tcgggtgtca tctccccaca taagaggatt ttcctgaaac aggagggaag 1440 cccggtgggg gattttctta taaacaagga tgaggagacc ctggggtgct cagcccacag 1500 ttccgacctt gccctcccca gccttccttt cccttggctg agtcaggttc tgtgggaacc 1560 cgggagggta gactggggtc ctccaagctg ggctgtgcga ctgggatgtg gtgtcactgg 1620 cagaggaagg gagcaaagca gtgctaggaa cagcaggcct ctgaggacaa aggtgtaact 1680 cacaccctcc agcgtttcca tgacggtagg ggctgcagtg tggctgctgt cattctacct 1740 cagaggtggg ggaaccccag ccagggccct gaccttccaa atcctctgtt gggggctcag 1800 ttgtgtattg tggttcacac attggctgat attccattca caaagaacat gccctcgact 1860 ccatgtctat ttgtgttgtt ttatgtgagt aatcttgcag gattaaaatc tagtaggagt 1920 cccttactca gcacttgctc aaagttctca gctgacactt ttgttgtaga gagacgccaa 1980 gtctatgcgg ggtgggtcct tcccgtagcc atgggcaccc aagtgtggta ggagccttag 2040 aaacgaggaa agtggggaga atcttctgag cactggcagg gaggggcggc tccacatcct 2100 cctttctaag gtggcgcctc cttctccccc aggtggtcag gacaagccct tgctgtctgc 2160 ctggcccagc actgtggtgc ctcgaggagg acatgtgact cttctgtgtc gctctcgtct 2220 tgggtttacc atcttcagtc tgtacaaaga agatggggtg cctgtccctg agctctacaa 2280 caaaatattc tggaagagca tcctcatggg ccctgtgacc cctgcacacg cagggaccta 2340 cagatgtcgg ggttcacacc cacgctcccc cattgagtgg tcagcaccca gcaaccccct 2400 ggtgatcgtg gtcacaggtc agaggactca tgtctgggct tctccttctc ccacttcctg 2460 aatcccagag catctggtgg gggtgtccac cagggtccaa tcatccaggc cctgactgta 2520 tttggtgtca atggggattg aatacagggg aatgggtgct gtggtggaaa gagtaactgt 2580 cggcagcatg gctatattgt aatccttgga gcctgtgact atttatgtta taggacatgg 2640 gactgaaggg gaagatggag ttcaggttgt tgatgagttg accttgagat ggggagacga 2700 cctggactct cccactgggc tcagtgtaat cacaagggtc cacatgagag gaggaggaag 2760 aggagagtgg ggattagagc agcgtagtgg gagggagagt ccaccagcca ctgcgggctt 2820 tgaaagtgga ggaaggccag aagctacgga atgcaggtgg cctttagggg ctggagaagt 2880 caatggaact gattctcccg agtctccaga gggaatgcag ccctgcagat gccttgattg 2940 tagcccagga agaacagggt ctgatttctg tcaacagaag tgttctctcc cgccgccgtg 3000 tttgtgataa ttttctgcag caacaacagg aaacaacaca ggaatccagg tcaaggacaa 3060 gttaaaaaac caaacaagag ggttggctac cctaaggtca gcaagggtgc actgctgatg 3120 ccaccaccag gctggagccg catagggagg gatccacagg gagagtcggg ggtggagggt 3180 gagagagaga gagagcatta ggtcatagag caggggagtg agttctcagc tcaggtgtga 3240 ggggagctgt gacaaggaag aacctccctg aggaaactac ctcttcttcc aggtctattt 3300 gggaaacctt cactctcagc ccagccgggc cccacggttc gcacaggaga gaacgtgacc 3360 ttgtcctgca gctccaggag ctcatttgac atgtaccatc tatccaggga ggggagggcc 3420 catgaaccta ggctccctgc agtgcccagc gtcaatggaa cattccaggc tgactttcct 3480 ctgggccctg ccacccacgg agggacctac acatgcttcg gctctctcca tgactcaccc 3540 tatgagtggt cagacccgag tgacccactg cttgtttctg tcacaggtga ggaaagccca 3600 tgcctgtccc atgtcctgtg atcctagagc cttagctgag gagcttcctg ctgatgatgg 3660 agagaagcat ggacagatgc agagagaaca cgcagcatgg tgtgagggag ggatcagggc 3720 acaggatggc agacagggca cctccaaacc ctcctgcacg gcctgcatgg aggcccgcgg 3780 ccagggctcc aggcacccag gcagatggag aaagtggtca ggacagaccc agaggagcga 3840 gactcggctc agtttgggga gatcagaggc tccctcagac cctaaacctt acccatttcc 3900 cagaagccca tactggcctc tcacccacac agagatgtca tcaccagcaa cccctacacc 3960 cttttctttc cgtttgaaaa aacatttatt taggttaaat gtaactatat aatttgccac 4020 ctttaccatt tttaaaagta aaatctagtg gtcataaatt cctttatatg cagggtgcag 4080 tggctcacag ttataatctc ggtgctttga gaggccaagg aaggtggatc atttaagatc 4140 agaggctcga gatcagcctg gccaacatga gggaaattca tctttactaa acagacaaga 4200 aaaattggct gggcatgctg gcatgcacct gtattcctag ctacatggga ggctgaggca 4260 ggagaagtac gtaagcccag gaggcagagg ttgcactgag ctgagatcag gccactgcac 4320 tgcagcctgg gagacagaga gagattctgt ctctaaataa ataaatacat ctatattctt 4380 ttttattgtt gttgttacac tccacccttt acttcctgcc ctctggtagc caccattcta 4440 ctctctacct tcatgagatc caccttttag ctcctgtata tgggtgagaa atgggaatct 4500 ttgcaatgac ctccagttcc atccatgtgg ctgcaaatgt caggatgtta ttctttctac 4560 ggatgagtac tctccactgt gtgtgtgtac tacattctct ctatccattc acccactgac 4620 gggcaggtaa gttgactcca catcttggct actgtgaaca gtgctgcacc aatcgtatga 4680 gtgcagatat cacttcgata cactgatgtc cttccctttg ggtttacacc cagtagtgga 4740 attgctagat cctatcaaca gggtaccagg gttctccttt ctctaccacc ttgccagcat 4800 ttattttgtc tgtgtttcag ataaaagcca ctttaatggg atgagatgat agctcactgt 4860 gatttcaatt ggcatgatta gtgatactga gcactttttc atgtacatgt tcgccatttg 4920 tacgttttgt ttgttgagaa atgtctgttc aggtctttta ctaattgtta aattaaattc 4980 attgttttat accgttgctt gagttttatg tatattctag ttattaatcc cctctcagat 5040 gcatacttca caaatatttt ctcccaattt gtctcttctt cactttgttg gttgcttcct 5100 ttgcggtgca gaagctgctt actttgatgt aatcccgaag gtctattatt ttgttttgat 5160 ttcttgtgtt tttgagattt caaataaaat gtctttcctc agacaaatgt cctggagcat 5220 ttccccactc tttcctttta gacgcttaat ggtttcaggc cttaagtgtt tcttccattt 5280 tcatttgatt tctgtgtatg gtgagaggta gaggtgcagt ttcatcaact gcatgtagat 5340 accagttttc cctgctccat ttattgaaaa gaccgtcgtt tcctgattgc aggttcttgg 5400 cacgtacaat cgtcaaagtc cattggatgt gaatgcatga attatatctg tgttcttcat 5460 tctgctccat tgctctaagg gcctttatgc caatgtcatg ctgttgtgct tactacagct 5520 ttgtaacata tttttaagtc agggagtgtg aggcctccag cacctgtttt gtctttatac 5580 ctcgaaatct caggacactg ggcatcattt aacaatgatg atggagaagg ggacgccagg 5640 actcctaggg cccaacatta gataacagag tgttggccat gaaccaacct caaagatttc 5700 ctttgagtag aagacaggca tcctcatttc ctcacctctc tcctgtcctg tgttctagga 5760 aactcttcaa gtagttcatc ttcacccact gaaccaagct ccaaaactgg tgagtaaaga 5820 tccctcttat ctctgctttt ggaaacctgg ggaggttggt atcttggatt caagcattgg 5880 ctcagcacct cccagctctg tgattgtggg cctgtcttct aacatctctg acccccagac 5940 actacaacag cgaagggtat ctgaggacag caaagggctc agtgaagtct cttcatttca 6000 aatttctgca gctgagacct cctccaagct agacggacga gtacaaatct gacatccttc 6060 tcagggataa agtggtgttt tttctgcctg cattccaaat tggaggataa atttgagggg 6120 acttgagaga gggaggggaa gggaacatct gatgagggaa aggtgattta gagaagttcc 6180 acttgccaag gaatgagccc ctgttggtca tgatgcgacc ttggctgagt cagcagagca 6240 agagccttgc agtaagaagg aacgtagttc atccacaaat atgacacttc cacttactca 6300 cttattcagc cactgccctg tgctctgact gtacagtgtg gaaccctttc ctgctgttgc 6360 cataataaat ctccacaaac ttcatggatg acaacaacac agcttttaaa attatcttac 6420 agtgttatag ctcagaaata tgaaatgcat ttcactgggc taaaatcaag gtgactgcga 6480 ggctgccttt tctctgaagg ttccaggcga gaatcggctt ttcacatttc ccagctccca 6540 gaggttccca cgttccttgg catctggtcc ccatcctcct tcctcgaagc ccacaaaagc 6600 tcatcacatc tctcacgtgg catcactcag atccctcttc cttacctcac ctctttctct 6660 aagtgttgct ctgacttttt cttcctcttt taaagacttt gggattctat tgagtttacc 6720 aagataatcc atcacaatct ccctaaaatc acccaagata acctcttttt aagttcagct 6780 gattagcaac cataattcca tctgcaatct ttattcctcc tttcatgtaa aataacatat 6840 tcacaagcta tggaggctag gacagggaca ttttgggggt gggccagcat tctcctgcct 6900 tccacaaatg gtaaacacga tgcatttggc ctctgctctt aggacactga cattgcagat 6960 gggcaaatgg gagggcagaa tatgaatgca caagtggacc agtaatgatt gatccattgg 7020 gaagcatccg tgcatgaaat ctatttacct atttatttat ctatttatct atttatgtat 7080 ttatttattt gcggcgaagt cattctctgt ccccgggctg gagtgcagtg gcatgacctc 7140 agctcaccac aacctccgcc tcccgggttc aggcgattct cctgcctcag cctcctgact 7200 agttgtgatt ccagtcccct ccaccacacc cagctaatat tcttttacat tttttagtag 7260 agatggagtt tcaccatgtt gcgcagattg tctccaactc ccaacctcaa gtgatccgac 7320 cgtctcagca tcccaaaatg ctgggactca aggtgtgaga cactgcgccc agccgaaatt 7380 taaaataaat aataaagaat tctaagtgta taatttcagg agacagagaa agtctcacta 7440 atcagataat atttgtgacc ataatgaaaa aaaaaagtag attcaacccc tggaagattg 7500 gcggaaggat tttccacaca cagctgtcag ccgtgaaggc acaaatgtga aaacaatctg 7560 atgtggaagg aagaggctct gcattcaaat gctgggaatg acgtggggag aatgacaaga 7620 cgactgtgga gagacggaga gcactctggg tacacaggaa actaaggagg aacaaggagc 7680 gtgtgtttga cactcacagc cattggattc acctcggggt agccaggaat ccctacatga 7740 ttaatatgac tgacatgaaa ataaggacgc ccaagtgcgt aactggaatc taggagaccg 7800 tggaaaaggc aattcccgcc ccactggtga aatgtggtgc tgatttagac actaaatgaa 7860 tgaagtagat gggtataaga tatgtctgtg aggtagaatc atttgtaggg agggcttgct 7920 ggatttgata atgcctactt atttaatttt gaatatatta atttctttct gagatttatt 7980 tttcctacat gtaaatcaat atctggcaga ggagtgattg atagatagat gaggggtggt 8040 gcaaatgaag ggacttatta tagcataata tacaagtctg tgaatgggag cttacgcctg 8100 taacccaaca ctttgggagg ccaaggcgtt tggatcactt gaggtcagga gtttgagacc 8160 agcctggcca acatggagaa accccatgct ctttttagca accagtccta gggacctcat 8220 ggagaacttg ccaaccacgt ctcatgggga cagcattaat gtattcatga tggatccacc 8280 cccataactg gaacgtctct caataggccc agcctcccac actgcgagat aagtgtcaac 8340 gtgaggtttg gcggggtcaa acatccaaac tatagcagtg gtatccccag catgttctct 8400 gattattttg agaactataa ctgagaaagc aggagaaagc tgggtatcct gccatcgggg 8460 aacttgtcct aaacagatgt tgtatgtgct tagctggcaa ccaagaaatg agagacaatc 8520 cataaagagg aactgctata attagcttct tattggattc ccaccttccc ccaggtatcc 8580 gcagacacct gcacattctg attgggacct cagtggctat catcctcttc atcatcctct 8640 tcttctttct ccttcattgc tgctgctcca acaaaaagag taagtctcac gaagcagagg 8700 tcagagagct caggaccatg tggggaagca ggatgggagc acactggtgt gtgttcctga 8760 ctggcaggat ggtccctgga ccaaggcagg agccacagag gcagggcttt ctagagagag 8820 caccagacac cctgcccctg ccttcagctc acagaccatt gcctgattct gaactgtatc 8880 ctcacgtccc ctgcagccac tgacatccag gagaaggttc catgacaggc agaaagggga 8940 gacagaatca ctgggatggg aactcagagc tattcatggg atgggtcctt gagctcagag 9000 agatagaatg tctgggtctg gctgatgaca gctgagggac ctcaggcacc tacggcctcc 9060 cgctgtgtgt tggtgtctgc tcatgaaatg aggacccaaa agtgcccttc cagctgtttt 9120 gatgacttct atctcctaca gatgctgctg taatggacca agagcctgcc ggggacagaa 9180 cagtgaacag ggaggtaggt tctcctcagc ccagcctcat ggattgagtc tcattcccta 9240 atagtcttga agaatgtgag caccctccct cactcagcat ttccctctct ccaggactct 9300 gatgatcaag accctcagga ggtgacatat gcacagttgg atcactgcgt tttcacacag 9360 acaaaaatca cttccccttc tcagaggccc aagacacctc caacagatac caccatgtac 9420 atggaacttc caaatgctaa gccaagatca ttgtctcctg cccataagca ccacagtcag 9480 gccttgaggg gatcttctag ggagacaaca gccctgtctc aaaaccgggt tgccagctcc 9540 catgtaccag cagctggaat ctgaaggcat cagtcttcat cttaggggat cgctcttcct 9600 cacaccacaa atctgaacat gcctctctct tgcttacaaa tgtctaaggt ccccactgcc 9660 tgctggagag aagacacact cctttgctta gcccacaatt ctctatttca cttgacccct 9720 gcccacctct ccaactgaac tggcttactt cctagtctac ttgaggctgc aatcacactg 9780 aggaactcac aattccagac atacaagagg ctccctctta acatggcact gagacacgtg 9840 ctgttccacc ttccctcatg ctgtttcacc tttcctcaga ctattttcca gacttctgtc 9900 agtcagcagt gaaacttata aaattttttg tgatttcaat gtagctgtct ccttttcaaa 9960 taaacatgtc tgccctcat 9979 //