Dbfetch
ID KIR00437; SV 1; standard; DNA; HUM; 11136 BP. XX AC KIR00437; XX SV KIR00437.1 XX DT 28-AUG-2009 (Rel. 2.3.0, Created, Version 1) DT 16-AUG-2010 (Rel. 2.10.0, Sequence Updated, Version 1) DT 16-DEC-2021 (Rel. 2.11.0, Current Release, Version 1) XX DE KIR2DL4*0080203, Human Killer-cell Immunoglobulin-like Receptor XX KW Human Killer-cell Immunoglobulin-like Receptor; KIR2DL4*0080203; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-KIR Release Version 2.11.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD Database, Distributed under the Creative Commons CC Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/licence.html for further details. CC -------------------------------------------------------------------------- XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC KIR Nomenclature Committee. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; GU182343; GU182343.0. XX FH Key Location/Qualifiers FH FT source 1..11136 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="Black" FT /cell_line="FH08" FT CDS join(268..307,507..542,1409..1693,..,5449..5499,9743..9846, FT 10308..10360,10460..10729) FT /codon_start=1 FT /gene="KIR2DL4" FT /allele="KIR2DL4*0080203" FT /product="KIR2DL4 Killer-cell Immunoglobulin-like Receptor" FT /translation="MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGG FT HVTLRCHYRRGFNIFTLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHS FT PTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEA FT HELRLPAVPSINGTFQADFPLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPS FT SSWPSPTEPSFKTGIARHLHAVIRYSVAIILFTILPFFLLHRWCSKKKMLLX" FT UTR 1..267 FT exon 268..307 FT /number="1" FT intron 308..506 FT /number="1" FT exon 507..542 FT /number="2" FT intron 543..1408 FT /number="2" FT exon 1409..1693 FT /number="3" FT intron 1694..2860 FT /number="3/4" FT intron 2861..5448 FT /number="4" FT exon 5449..5499 FT /number="5" FT intron 5500..9742 FT /number="5" FT exon 9743..9846 FT /number="6" FT intron 9847..10307 FT /number="6" FT exon 10308..10360 FT /number="7" FT intron 10361..10459 FT /number="7" FT exon 10460..10729 FT /number="8" FT UTR 10730..11136 SQ Sequence 11136 BP; 2827 A; 2672 C; 2678 G; 2959 T; 0 other; gcaggggtaa gtgagtctga gatgtgtttt gagcctggcc gttgcgcatg atgtgaagtg 60 acaagtctag tctgcagttt tcagaaaccc tcattcctcc cttgactgat tcaccacttg 120 aacctcatat gacgtagaag aagcctacct atgtcccctt cacatgttgt ggtcaatgtg 180 tcaactgcac gatccgggcc cctcaccaca tcctctgcac cggtcagtcg agccgagtca 240 ctgcgtcctg gcagcagaag ctgcaccatg tccatgtcac ccacggtcat catcctggca 300 tgtcttggtg agtcctggaa gggaaggagc accagggtta cactatgggc ctgcagattg 360 ggtgtctccc cagcagagag ccatgttctg aagcaagtga gtggtgagga tgagttaatt 420 ttcagtccag cgtggcgccc agtggctcag gaggaaaggg taggttggtg ccgagatgaa 480 tagttcatca tgatctttct ttgcagggtt cttcttggac cagagtgtgt gggcacacgt 540 gggtgagtcc ttccccaaat gatgggttgc catcttcacc ccaatacaag tgaattttcc 600 ggaaatggga gggaggcagc acagagggtg ggctgatggg ctgaccatgg gaaggcctgg 660 ggggagtctc tcatgaacta gtaagaggag atcctgggag tctctcatga actagtaaga 720 ggagatcttg ggagtctctc atgaactagt aagaggagat cctggtatgc tcagccttct 780 gttttgtctt agccctcccc agcctttctt ccccatggct gagttgagct ctgtgtggcc 840 caggcgggat actgaggtgc tcaaagctgg ggtgtgtggg gggatgtggt gtcaccgaca 900 gaggagggaa gggtagcagt gttaggaaca gcaggtcctc tgaggacaag agggtaactc 960 acaccctcca gcgtttccat gacggtaggg gctgcagtgt ggctgctgtc attctgccag 1020 aagaggtggg ggaaccacag ccacgaccct gccattccaa atcctctgat ggagctcagt 1080 tgtttattgt ggttcaggca ttagctaata ttccattcac aaaggtcata ccctccaccc 1140 catgtctact ttgtgttgtt tggtgtaact aatcttgcag tattaaaatc tagtaagagt 1200 cccttactca gcacctgctc agttctcaac tgacactttt gttgtaggga gacgccacgt 1260 ctatgcggga tgggtccttc ctgtagcccc aggcacccag gtgtggtagg agccttagaa 1320 agaagaaatg gggagaatct tctgagcaca gggagggagg ggcagctcaa catactcctc 1380 tctgaggcgg catctccttc tccccaaggt ggtcaggaca agcccttctg ctctgcctgg 1440 cccagcgctg tggtgcctca aggaggacac gtgactcttc ggtgtcacta tcgtcgtggg 1500 tttaacatct tcacgctgta caagaaagat ggggtccctg tccctgagct ctacaacaga 1560 atattctgga acagtttcct cattagccct gtgaccccag cacacgcagg gacctacaga 1620 tgtcgaggtt ttcacccgca ctcccccact gagtggtcgg cacccagcaa ccccctggtg 1680 atcatggtca caggtcagag ggctcctgtc tgggcttctc cttgtcccac ctcctgagtc 1740 ccagagcttc tggtgggggt gtccaccaga gtccgatcat ccaggcccca actatatttg 1800 gggtaaaggg ggattgaata caggggaatg ggtgctgtgt tggaaagaat aactgtcccc 1860 atcgatggcc acattgtaat ccttggagcc tgtgactatg ttatagggca ggggactgaa 1920 ggggaagatg gagctcaggt tgttgatgag ttgaccttga gatggggaga tggcctggac 1980 tctcccactg ggctcagtgt aatcacaagg gtccatatga gtggagaagg aagaggagaa 2040 tggggattag agcagcatcg tgggatactc caccagccac tgtgggcttt gaaggtggag 2100 gaagaccacg agccacgaag gggctggaga aatcaatgga actgattctc ccgagtctcc 2160 agagggaatg cagccctgca gatgccttga ttgtagccca ggaagaacag ggtctgattt 2220 ctgtctccag aagtggaagg ggtcagtgtg ttctctcctg ccgccatgtt tgtgataatt 2280 ttctccagca acaacaggaa accaacacag gaacccaggt gaaggacaag ttaaaaaacc 2340 aaacaagaag gttggctacc ctgagatcag caagggtgca ctgctgatgc caccaccagg 2400 ctggaaccac atagggaggg atcgacagga agagttaggg gtggagggtg agagagagag 2460 agagagcact aggccataga gcagggcagt gagttctcag ctcaggtggg aggggagctg 2520 tgacaaggaa gaacctccct gaggaaactg cctcttctcc ttccaggtct atatgagaaa 2580 ccttcgctta cagcccggcc gggccccacg gttcgcgcag gagagaacgt gaccttgtcc 2640 tgcagctccc agagctcctt tgacatctac catctatcca gggaagggga agcccatgaa 2700 cttaggctcc ctgcagtgcc cagcatcaat ggaacattcc aggccgactt ccctctgggt 2760 cctgccaccc acggagagac ctacagatgc ttcggctctt tccatggatc tccctacgag 2820 tggtcagacc cgagtgaccc actgcctgtt tctgtcacag gtgaggaaag ccaatgtctg 2880 tcccatgtcc tatggtccta gagccttagc tgaggagctt cctgctgatg atggagagaa 2940 gcatggacag atgtggagag aagatgcagc atggtgtgag ggtgggatca gggcacagga 3000 tggcagacag ggcacctcca aaccctcctg catggcctgc atggaagctt gcagtaaggg 3060 ctccgggtac ccaggcagat ggagaaagtg gtcaggacag acccagagga gggagactgg 3120 gctcagtttg gggagatcag aggttccctc agcccctcaa ccttacccat ttcccagaag 3180 cccaccctgg cctctcacct acacagagat gtcatcacca gcaaccccta cactttttct 3240 tttcctttga aaaaatgctg attgaggtta aatataccta tataatttat caactttacc 3300 atttttaagt gtaaaatcta gggatcataa atacctttat atgctgtgtg cggtggctca 3360 cgcctgtaat ctcagcattt tgagatgcca aggcaggtgg atcatttaaa atcaggggct 3420 ggagaccagc ctggccaaca tgggggaacc aatctttact aaaaagacaa aaaaaataaa 3480 attagccagg catggtgcca ggcgcctata atcccagcaa cttgggaggc tgaggcggga 3540 gagtggctta aacccaggag gaggaggttg cagtgagctg agatcatgcc actgcactgc 3600 agcctggtga cacagagaga ctctgtctct aaataaataa ataaatactt ttatattctt 3660 cttttgttac cctccacccc ttccttccta acctctggta tccaccattc tactctctac 3720 cttcatgagg tccacctttt acatcctgca tgtgagtaag aaatggcaat ccttgtaatg 3780 acctccagtc catccatgtg gctgcaaatg acaggacgtt actctttgta tggatgagtt 3840 gtctccattg tgtgtatgta ctacattctc tctatccatt catccactga tgggcaggta 3900 ggttgactcc acatcttggc tactgtgaac agtgctggaa cagtcatggg agtgcagatg 3960 tcacttcaat acactgaagt ccttttcttt gcatttacac ccactagtgg aattgctaga 4020 tcctctggat gttctctttt taggttttgt tttatgcttt ttgttttttt gacatagcgt 4080 ttcactcttg ttgcccaagc tggagtgcaa tggcaccacc tgggctcact gcaacctcta 4140 cctccaggat tcaagtgatt ctccagcctc agcctcccga gtagttggga ttactggtgc 4200 ccgccaccac gcctggctga tttttgtatt tttagtagag acggggtttc accatgttag 4260 ccaggctggt ctcgaactct tgacctccag tgatctgccc acttcagcct cccaaggtgc 4320 cgggattaca agcgtgagcc acagtgccta atctcttttt agtttttaag gaacttccat 4380 attcttctcc tctgtaatgg ctgtattaat ttacattcct atcaacagtg tatcagggtt 4440 ctcctttctc caccaccttg ccaacatttg ttttgtctgt ctctgagata aaacccattg 4500 taatggggtg agatgatagc tcattgtgac ttcatttgca tttctctgat gattagtgat 4560 actgagcact ttttcatata tgcaatgtat atatgttcat ttgtatgttt tgttcattga 4620 gaaatgtctg ttcaggtctt ttactaattt tataattaaa ttattagttt tattgaggtg 4680 tttgagcttc ttttatattc tagttattaa tcccatctca gatgcatagt ttgcaaatat 4740 ttgctcccat tctgtgggtt gtctcttctt cacttcattg gttgcttcct ttgcggtgca 4800 gaagctgctt gatttgatat aatcccaatg gtctattttt ttgttgttgt tgtgattact 4860 tgtgtttttg aggttttaaa caaaatgtct tccctcagac aaatgtcctg gagcatttct 4920 ccagtgtttc cttttagaca tttaatggat tcaggtctta agtcattaat ccattttcat 4980 ctgatttttg tgtatggtga gaggtagagg tgcagtttca tccctctgca tgtagatatc 5040 cagttttccc tgcaccattt attgaaatga ctgtcctttc cagattgtag attcttcgaa 5100 cctttgtcaa agtccattgg atgtaaatgg gtggattaca tccgtgttct tcattctgct 5160 ccattgtttt atgtgctttt ctttatgcca atgtcatgtt gttttgctta ctacagctct 5220 gtaacatatt tttaagtcag gtagtgtgat gctcctgttt tctccttata ccttgaagtc 5280 tcaagatagt tggtgtcacc tacaatgatt atggagaatg ggatgccagg actcccaggg 5340 cccaacatta gataatagaa tgttggccat gaaccaacct caaagatttc cattgagtag 5400 aagacaggca tcctcattgc cacacctctc tcctgtccca tgttctagga aacccttcta 5460 gtagttggcc ttcacccact gaaccaagct tcaaaactgg taagtgaagg acccctctta 5520 tctctgcttt tggaaacctg gggaggtaga agccttggat tcaagcgttg gctcagcacc 5580 tgccagctct gtgattgtgg gcctgtcttc cattgtctct gaaccccaga cactccaaca 5640 gcgaaaggga tctgggccca gcacagggct cagtgaaatc tcttaatctc taattttctg 5700 ctgctgagac ctcagggtag aaggatgagt gcaaatcaga cattcttctc aggaaaaatg 5760 ctgtgtttgt tctgcctgca ttcctaactg ggaggacaaa tgcctggggg cttgagaagg 5820 ggaaggaagg ggaacatttt tgagggtggt gtatttgtag agaagttcta cttgccaagg 5880 aatgagctcc tgtctgtcat gatccaaccc tggttgactt agtggaacaa gagctttgcg 5940 gtaagagaga acgtagttca tccgtgcaca tgacacttcc acttactcgt tcagccactg 6000 ccccatgctc agactgtgca gtgtggaacc ttttcctatg ttgccataac aaatttccac 6060 aagcttcgtg gatggaaacc acatttttaa aaaatatctc atggtgctgt agctcagaag 6120 tatgaaatgc atcatctcac tgggctaaaa tcaaggtgac agcaaggctg ccttccctct 6180 gaatgttcca ggcaagaatc tgcttcctca cttttcccag ctcctagagg ctcccacatt 6240 ccttggctcc tggtccccgt cttcctccct caaagtccac aaaggctggt cacgcctctc 6300 acacggcatc actcagaccc ttcttccttg tccacacctc tttctctgaa tgctgctctg 6360 ccttcttcct catcttttaa ggactttggc attctattgg aaacaccaag ataatccatc 6420 ataatttccc taaaatcatc taggataccc tccttttaag gttagctgat tagcaaccgt 6480 aattccatct gcaatctgca ttcctttttt ccatgtaaaa taacatattc acaagatatg 6540 gcgactagga caggaatatt ttggggtggg gcggcattct tatcctttcc acaaatggta 6600 aacaaggtgc atttggcctc tgctcttgga cactgatatt gcaaaggatt aaatgggagg 6660 gcagaaaatg aatgcaccag tggaccaata aatgaatgat ccattgggaa gcatctgtgc 6720 atgagaatga ttgattgatt ggtgttttta tgagacggtg tctccttctg tgccccaggc 6780 tggagtgcag tggcgggatc tcggctcacc gcaacctcca cctcccaggt taaagcgatt 6840 ctctacactc agcttcccga gaggctggga ttacacccat gtcccaccac gcctggctaa 6900 tttttttttt ggtatttttt tttagtacag acaaggtttt accatgttgc ccaggctatc 6960 tcaaactccc aaccttaagg gatccgcccg tctcagcctc ccaaagtgct gagattagag 7020 gcgtgagcca aggcgccgag ccgtatttta aaagaaataa tagataatgc tgagtgtata 7080 atttcgggtg acagagaagt tctcactgat caaataatac ttgtgacctt aatgaaaaaa 7140 atagatcaac ccctggaaga ttggcggaag gattttccac acagctgtca gccgtgaagg 7200 cacaaaggtg aaaacaatgt tatgtggaag gaagaggctc tgcctcaaat gctgggaatg 7260 aggtggggag aatgacaaga cgactgtgga gagacagaga gcactctggg tacacaggaa 7320 actaaggagg aacaaggagc gtgtgtttga cactcacagc ccttggactt acctcggggc 7380 taactgggaa tccctacatg atgaatagtg actgacatga aaataaggga ggcccaggtg 7440 cataactgga atctaggaga ctgtggaaaa ggcaattccc gcccccctgg tgaaatgtgg 7500 tgctgattta gacactaaat gaatgaaaga tggacacaag atgtgtttgt gaggtagagt 7560 aatttgcagg gagggcttgc ctggtttgat ttttcctaat tgtttaatct tcacttcatt 7620 gatttctttc tgagatttat ttttcctaca tgtaaatcaa tacttggcag aggagtgaga 7680 gatacatgag gggtggtgca aaggaagaga cctattataa tataacacac aaggttctga 7740 acggtggctc acacctgtaa cccaacattt tgggaggctg aggaggctgg atcaagtgag 7800 atcaggagtt cgagatcagc ctggacaaca tggtgaaacc ccatctctac taaatataca 7860 aaaactagct gggggtggtg gcgcatgcct gtaataccag ctattcggga agttgaagaa 7920 ggagaatggc ttcaaccagg gagggagagg ttacagtgag ccaagatcgc gtcattgcac 7980 tgcaccctag gtgacagagt gagactccat ggcaaaaaat aaaaataaag aatacataaa 8040 tataatataa catacacgaa tgacaaaggc acaccaattc caatcatcat ttttctattt 8100 ctctataatg acttctttga tcctttatcc tatccgtaag aaaatcaggc gaaaacatct 8160 tccttatttg gctttctgtg agcatgagat catatggaaa atgtgaaacc caccagcaca 8220 ggtcctggaa tagagaacgt gatctgttca tggcacaaaa cttgcccctt cacccaaatc 8280 ccccacctca cccctacttc caatcacatt aatgatacag atagatcatg gggaggtaaa 8340 aactaatatt ctttggagtt cagatcgtag actcagagac cagtgccagc actatctcct 8400 ggtcaccttt tggagtaatt cacagaaaga caggctgtat tgaagcaaca gatgatggag 8460 ggggtggtct ttcccccaga ctctcgggtg gaacagcagc ctaatatctg actcccaaga 8520 tgacaaaagt agcatgttgc ccacgagctt catcattatt tcctggctgt ttgatataag 8580 acagctcaac ctcacttatg ttgatttcaa tgtcactgtt ttttcctttt cttggagaat 8640 gtaatttgtt tgagtcaaga gggttgtgga tgtagaaact gtaaagcaca ttcactgtgt 8700 atcaatccca gtccagtctt cccagagaag actctaaaca cctcccatac tgcacctggg 8760 ggctgtgcca atttctatca ctcaccatca ctccagggag acagaacaca cagggaatac 8820 attacatagg caggttcatt acttatagat aagcagcgag tgacaacaga aaccttcctt 8880 tcagggtgag ccagtccctc aaggctcaga aaaactgctc aggacacatg gagtcacttc 8940 atgtgcactg tagctggggg aagccagaaa gcagcccagc ctgggttttg taccctggag 9000 ccacagggaa cactcagcta aagcactgca tgatgttctc ctccaggaag aacaggaaga 9060 cagcccaggc tgttctgaga cgttcctcct gatctcagga tgttgctgtc ttagcctatt 9120 tttgttgcta taaaagaaca cttgagcctg ggtatcttct aaagaaaaga gatgtgtttg 9180 gctcactgat ctgcacgctg tactagaagc aggacactac catctatttc tggctgcggc 9240 ctcaggctgc tcccacactg acagaagaga agggggtcct gcgtgtgcag agaccacaga 9300 gatcacatgg caagagaggg agaaaggggg tgtgatggag cttccaagct ctttttaaga 9360 atcaactctc cagggtacta atagagggag aacttgctaa ccccgtcctc tggggacagc 9420 attaatctat tcatgatgga tccaccccca tgaccaaaac acccctccca ataggcacaa 9480 cctcccacac tggggattaa atttcaaagt ggggtttgga ggggtcaaac attgaaacaa 9540 tagcagttgt atcatcagca cattctattg ttattatgaa aactataacg gagaaagcag 9600 gagaaagctg ggtctcccgc ctcgtgggtg cttgtcttaa agaggtgttt tatgtggttg 9660 cctggcaacc aagaaatgag agacaatcca caaagaggaa ctgctatggt tagcttctta 9720 ttggattccc atcttcctcc aggtatcgcc agacacctgc atgctgtgat taggtactca 9780 gtggccatca tcctctttac catccttccc ttctttctcc ttcatcgctg gtgctccaaa 9840 aaaaaagtaa gcctcacgaa gcagaggcca gagaactcag ggccctgtgc ggaagcagga 9900 tgggagcacg caggtgtgtg ttcctcactg gcaggaaagt ctctggccca aggcaggagc 9960 cagaggcaga gctttctaga gagagcacca gacaccctgc ccctgccttc agctcacaga 10020 ccgttgcctg attgtgaact gtatcctcac gtcccctgca gccactcaca tccaggagaa 10080 gattccatga caggcagaaa gtgggagata gaatcaatgg gatgggaact gacagctatt 10140 catggaatgg ggtcttgcac tcagagagat ggaatgtctg agtctggctg ttggcagctg 10200 agggacctca gacacctatg gcctccccct gtgtgttggt atctgttcat gaaatgagga 10260 cccagaagtg ccctcccagc tgttttgatt gcttccgtct cctacagatg ctgctgtaat 10320 gaaccaagag cctgcgggac acagaacagt gaacagggag gtaggtcctc ctagcccagc 10380 ctcatggata cagtcttatt ccgaaatagt cctgaaaaat gtgaacaccc tccctcactc 10440 aggatttccc tctctccagg actctgatga acaagaccct caggaggtga catacgcaca 10500 gttggatcac tgcattttca cacagagaaa aatcactggc ccttctcaga ggagcaagag 10560 accctcaaca gataccagcg tgtgtataga acttccaaat gctgagccca gagcgttgtc 10620 tcctgcccat gagcaccaca gtcaggcctt gatgggatct tctagggaga caacagccct 10680 gtctcaaacc cagcttgcca gctctaatgt accagcagct ggaatctgaa ggcgtgagtc 10740 tccatcttag agcatcactc ttcctcacac cacaaatctg gtgcctgtct cttgcttacc 10800 aatgtctaag gtccccactg cctgctgcag agaaaacaca ctcctttgct tagcccacaa 10860 ttctctattt cacttgaccc ctgcccacct ctccaaccta actggcttac ttcctagtct 10920 acttgaggct gcaatcacac tgaggaactc acaattccaa acatacaaga ggctctctct 10980 taacacggca cttagacacg tgctgttcca ccttccctcg tgctgttcca cctttcctca 11040 gactattttt cagccttctg gcatcagcaa accttataaa atttttttga tttcagtgta 11100 gttctctcct cttcaaataa acatgtctgc cttcat 11136 //