Dbfetch
ID KIR00422; SV 1; standard; DNA; HUM; 11177 BP. XX AC KIR00422; XX SV KIR00422.1 XX DT 28-AUG-2009 (Rel. 2.3.0, Created, Version 1) DT 16-AUG-2010 (Rel. 2.10.0, Sequence Updated, Version 1) DT 16-DEC-2021 (Rel. 2.11.0, Current Release, Version 1) XX DE KIR2DL4*0010305, Human Killer-cell Immunoglobulin-like Receptor XX KW Human Killer-cell Immunoglobulin-like Receptor; KIR2DL4*0010305; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-KIR Release Version 2.11.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD Database, Distributed under the Creative Commons CC Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/licence.html for further details. CC -------------------------------------------------------------------------- XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC KIR Nomenclature Committee. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; GU182340; GU182340.0. DR EMBL; LR593616; LR593616.0. XX FH Key Location/Qualifiers FH FT source 1..11177 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="Hispanic" FT /cell_line="DKMS-LSL_ID14830515" FT /cell_line="FH06" FT CDS join(268..307,507..542,1443..1727,..,5490..5540,9783..9887, FT 10349..10401,10501..10770) FT /codon_start=1 FT /gene="KIR2DL4" FT /allele="KIR2DL4*0010305" FT /product="KIR2DL4 Killer-cell Immunoglobulin-like Receptor" FT /translation="MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGG FT HVTLRCHYRRGFNIFTLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHS FT PTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRTGENVTLSCSSQSSFDIYHLSREGEA FT HELRLPAVPSINGTFQADFPLGPATHGETYRCFGSFHGSPYEWSDASDPLPVSVTGNPS FT SSWPSPTEPSFKTGIARHLHAVIRYSVAIILFTILPFFLLHRWCSKKKNAAVMNQEPAG FT HRTVNREDSDEQDPQEVTYAQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRA FT LSPAHEHHSQALMGSSRETTALSQTQLASSNVPAAGI" FT UTR 1..267 FT exon 268..307 FT /number="1" FT intron 308..506 FT /number="1" FT exon 507..542 FT /number="2" FT intron 543..1442 FT /number="2" FT exon 1443..1727 FT /number="3" FT intron 1728..2894 FT /number="3/4" FT intron 2895..5489 FT /number="4" FT exon 5490..5540 FT /number="5" FT intron 5541..9782 FT /number="5" FT exon 9783..9887 FT /number="6" FT intron 9888..10348 FT /number="6" FT exon 10349..10401 FT /number="7" FT intron 10402..10500 FT /number="7" FT exon 10501..10770 FT /number="8" FT UTR 10771..11177 SQ Sequence 11177 BP; 2845 A; 2682 C; 2683 G; 2967 T; 0 other; gcaggggtaa gtgagtctga gatgtgtttt gagcctggcc gttgcgcatg atgtgaactg 60 acaagtctag tctgcagttt tcagaaaccc tcattcctcc cttgactgac tcaccacttg 120 aacctcatat gacgtagaag aagcctacct atgtcccctt cacatgttgt ggtcaatgtg 180 tcaactgcac gatccgggcc cctcaccaca tcctctgcac cggtcagtcg agccgagtca 240 ctgcgtcctg gcagcagaag ctgcaccatg tccatgtcac ccacggtcat catcctggca 300 tgtcttggtg agtcctggaa gggaaggagc accagggtta cactatgggc ctgcagattg 360 ggtgtctccc cagcagagag ccatgttctg aagcaagtga gtggtgagga tgagttaatt 420 ttcagtccag cgtggcgccc agtggctcag gaggaaaggg taggttggtg ccgagatgaa 480 tagttcatca tgatctttct ttgcagggtt cttcttggac cagagtgtgt gggcacacgt 540 gggtgagtcc ttccccaaat gatgggttgc catcttcacc ccaatacaag tgaattttcc 600 ggaaatggga gggaggcagc acagagggtg ggctgatggg ctgaccatgg gaaggcctgg 660 ggggagtctc tcatgaacta gtaagaggag atcctgggag tctctcatga actagtaaga 720 ggagatcctg ggagtctctc atgaactagt aagaggagat cctgggagtc tctcatgaac 780 tagtaagagg agatcctggt atgctcagcc ctctgttttg tcttagccct ccccagcctt 840 tcttccccat ggctgagttg agctctgtgt ggcccaggcg ggatactgag gtgctcaaag 900 ctggggtgtg tggggggatg tggtgtcacc gacagaggag ggaagggtag cagtgttagg 960 aacagcaggt cctctgagga caagagggta actcacaccc tccagcgttt ccatgacggt 1020 aggggctgca gtgtggctgc tgtcattctg ccagaagagg tgggggaacc acagccacga 1080 ccctgccatt ccaaatcctc tgatggagct cagttgttta ttgtggttca ggcattagct 1140 aatattccat tcacaaaggt cataccctcc accccatgtc tactttgtgt tgtttggtgt 1200 aactaatctt gcagtattaa aatctagtaa gagtccctta ctcagcacct gctcagttct 1260 caactgacac ttttgttgta gggagatgcc acgtctatgc gggatgggtc cttcctgtag 1320 ccccaggcac ccaggtgtgg taggagcctt agaaagaaga aatggggaga atcttctgag 1380 cacagggagg gaggggcagc tcaacatact cctctctgag gcggcatctc cttctcccca 1440 aggtggtcag gacaagccct tctgctctgc ctggcccagc gctgtggtgc ctcaaggagg 1500 acacgtgact cttcggtgtc actatcgtcg tgggtttaac atcttcacgc tgtacaagaa 1560 agatggggtc cctgtccctg agctctacaa cagaatattc tggaacagtt tcctcattag 1620 ccctgtgacc ccagcacacg cagggaccta cagatgtcga ggttttcacc cgcactcccc 1680 cactgagtgg tcggcaccca gcaaccccct ggtgatcatg gtcacaggtc agagggctcc 1740 tgtctgggct tctccttgtc ccacctcctg agtcccagag cttctggtgg gggtgtccac 1800 cagagtccga tcatccaggc cccaactata tttggggtaa agggggattg aatacagggg 1860 aatgggtgct gtgttggaaa gaataactgt ccccatcgat ggccacattg taatccttgg 1920 agcctgtgac tatgttatag ggcaggggac tgaaggggaa gatggagctc aggttgttga 1980 tgagttgacc ttgagatggg gagatggcct ggactctccc actgggctca gtgtaatcac 2040 aagggtccat atgagtggag aaggaagagg agaatgggga ttagagcagc atcgtgggat 2100 actccaccag ccactgtggg ctttgaaggt ggaggaagac cacgagccac gaaggggctg 2160 gagaaatcaa tggaactgat tctcccgagt ctccagaggg aatgcagccc tgcagatgcc 2220 ttgattgtag cccaggaaga acagggtctg atttctgtct ccagaagtgg aaggggtcag 2280 tgtgttctct cctgtcgcca tgtttgtgat aattttctcc agcaacaaca ggaaaccaac 2340 acaggaaccc aggtgaagga caagttaaaa aaccaaacaa gaaggttggc taccctgaga 2400 tcagcaaggg tgcactgctg atgccaccac caggctggaa ccacataggg agggatcgac 2460 aggaagagtt gggggtggag ggtgagagag agagagagag cactaggcca tagagcaggg 2520 cagtgagttc tcagctcagg tgggagggga gctgtgacaa ggaagaacct ccctgaggaa 2580 actgcctctt ctccttccag gtctatatga gaaaccttcg cttacagccc ggccgggccc 2640 cacggttcgc acaggagaga acgtgacctt gtcctgcagc tcccagagct cctttgacat 2700 ctaccatcta tccagggagg gggaagccca tgaacttagg ctccctgcag tgcccagcat 2760 caatggaaca ttccaggccg acttccctct gggtcctgcc acccacggag agacctacag 2820 atgcttcggc tctttccatg gatctcccta cgagtggtca gacgcgagtg acccactgcc 2880 tgtttctgtc acaggtgagg aaagccaatg tctgtcccat gtcctatggt cctagagcct 2940 tagctgagga gcttcctgct gatgatggag agaagcatgg acagatgtgg agagaagatg 3000 cagcatggtg tgagggcggg atcagggcac aggatggcag acagggcacc tccaaaccct 3060 cctgcatggc ctgcatggaa gcttgcagta agggctccgg gtacccaggc agatggagaa 3120 agtggtcagg acagacccag aggagggaga ctgggctcag tttggggaga tcagaggttc 3180 cctcagcccc tcaaccttac ccatttccca gaagcccacc ctggcctctc acctacacag 3240 agatgtcatc accagcaacc cctacacttt ttcttttcct ttgaaaaaat gctgattgag 3300 gttaaatata cctatataat ttatcaactt taccattttt aagtgtaaaa tctagggatc 3360 ataaatacct ttatatgctg tgtgcggtgg ctcacgcctg taatctcagc attttgagac 3420 gccaaggcag gtggatcatt taaaatcagg ggctggagac cagcctggcc aacatggggg 3480 aaccaatctt tactaaaaag acaaaaaaaa taaaattagc caggcatggt gccaggcgcc 3540 tataatccca gcaacttggg aggctgaggc gggagagtgg cttaaaccca ggaggaggag 3600 gttgcagtga gctgagatca tgccactgca ctgcagcctg gtgacacaga gagactctgt 3660 ctctaaataa ataaataaat aaatactttt atattcttct tttgttaccc tccacccctt 3720 ccttcctaac ctctggtatc caccattcta ctctctacct tcatgaggtc caccttttac 3780 atcctgcatg tgagtaagaa atggcaatcc ttgtaatgac ctctagtcca tccatgtggc 3840 tgcaaatgac aggacgttac tctttctatg gatgagttgt ctccattgtg tgtatgtact 3900 acattctctc tatccattca tccactgatg ggcaggtagg ttgactccac atcttggcta 3960 ctgtgaacag tgctggaaca gtcatgggag tgcagatgtc acttcaatac actgaagtcc 4020 ttttctttgc atttacaccc actagtggaa ttgctagatc ctctggatgt tctcttttta 4080 ggttttgttt tatgcttttt gtttttttga catagcgttt cactcttgtt gcccaagctg 4140 gagtgcaatg gcaccacctg ggctcactgc aacctctacc tccaggattc aagtgattct 4200 ccagcctcag cctcccgagt agttgggatt actggtgccc gccaccaagc ctggctgatt 4260 tttgtatttt tagtagagac ggggtttcac catgttagcc aggctggtct cgaactcttg 4320 acctccagtg atctgcccac ttcagcctcc caaggtgctg ggattacaag cgtgagccac 4380 agtgcctaat ctcttttcag tttttaagga acttccatat tcttctcctc tgtaatggct 4440 gtattaattt acattcctat caacagtgta tcagggttct cctttctcca ccaccttgcc 4500 aacatttgtt ttgtctgtct ctgagataaa acccattgta atggggtgag atgatagctc 4560 attgtgactt catttgcatt tctctgatga ttagtgatac tgagcacttt ttcatatatg 4620 caatgtatat atgttcattt gtatgttttg ttcattgaga aatgtctgtt caggtctttt 4680 actaatttta taattaaatt attagtttta ttgaggtgtt tgagcttctt ttatattcta 4740 gttattaatc ccatctcaga tgcatagttt gcaaatattt gctcccattc tgtgggtttt 4800 ctcttcttca cttcattggt tgcttccttt gcggtgcaga agctgcttga tttgatataa 4860 tcccaatggt ctattttttt tgttgttgtt gtgattactt gtgtttttga ggttttaaac 4920 aaaatgtctt ccctcagaca aatgtcctgg agcatttctc cagtgtttcc ttttagacat 4980 ttaatggatt caggtcttaa gtcattaatc cattttcatc tgatttttgt gtatggtgag 5040 aggtagaggt gcagtttcat ccctctgcat gtagatatcc agttttccct gcaccattta 5100 ttgaaatgac tgtcctttcc agattgtaga ttcttcgaac ctttgtcaaa gtccattgga 5160 tgtaaatggc tggattacat ccgtgttctt cattctgctt cattgtttta tgtgcttttc 5220 tttatgccaa tgtcatgttg ttttgcttac tacagctctg taacatattt ttaagtcagg 5280 tagtgtgatg ctcctgtttt ctccttatac cttgaagtct caagatagtt ggtgtcacct 5340 acaatgatta tggagaatgg gatgccagga ctcccagggc ccaacattag ataatagaag 5400 gttggccatg aaccaacctc aaagatttcc attgagtaga aaagacaggc atcctcattg 5460 ccacacctct ctcctgtccc atgttctagg aaacccttct agtagttggc cttcacccac 5520 tgaaccaagc ttcaaaactg gtaagtgaag gacccctctt atctctgctt ttggaaacct 5580 ggggaggtag aagccttgga ttcaagcgtt ggctcagcac ctgccagctc tgtgattgtg 5640 ggcctgtctt ccattgtctc tgaaccccag acactccaac agcgaaaggg atctgggccc 5700 agcacagggc tcagtgaaat ctcttaatct ctaattttct gctgctgaga cctcagggta 5760 gaaggatgag tgcaaatcag acattcttct caggaaaaat gctgtgtttg ttctgcctgc 5820 attcctaact gggaggacaa atgcctgggg gcttgagaag gggaaggaag gggaacattt 5880 ttgagggtgg tgtgtttgta gagaagttct acttgccaag gaatgagctc ctgtctgtca 5940 tgatccaacc ctggttgact tagtggaaca agagctttgc ggtaagagag aacgtagttc 6000 atccgtgcac atgacacttc cacttactcg ttcagccact gccccatgct cagactgtgc 6060 agtgtggaac tttttcctat gttgccataa caaatttcca caagcttcgt ggatggaaac 6120 cacattttta aaaaatatct catggtgctg tagctcagaa gtatgaaatg catcatctca 6180 ctgggctaaa atcaaggtga cagcaaggct gccttccctc tgaatgttcc aggcaagaat 6240 ctgcttcctc acttttccca gctcctagag gctcccacat tccttggctc ctggtccccg 6300 tcttcctccc tcaaagtcca caaaggctgg tcacgcctct cacacggcat cactcagacc 6360 cttcttcctt gtccacacct ctttctctga atgctgctct gccttcttcc tcatctttta 6420 aggactttgg cattctattg gaaacaccaa gataatccat cataatttcc ctaaaatcat 6480 ctaggatacc ctccttttaa ggttagctga ttagcaaccg taattccatc tgcaatctgc 6540 attccttttt tccatgtaaa ataacatatt cacaagatat ggcgactagg acaggaacat 6600 tttggggtgg ggcggcattc ttatcctttc cacaaatggt aaacaaggtg catttggcct 6660 ctgctcttgg acactgatat tgcaaaggat taaatgggag ggcagaaaat gaatacacca 6720 gtggaccaat aaatgaatga tccattggga agcatctgtg catgagaatg attgattgat 6780 tggttgtttt tatgagacgg tgtctccctc tgtgccccag gctggagtgc agtggcggga 6840 tctcggctca ccgcaacctc cacctcccag gttaaagcga ttctctacac tcagcttccc 6900 gagaggctgg gattacaccc atgtcccacc acgcctggct aatttttttt tggtattttt 6960 ttttagtaca gacaaggttt taccatgttg cccaggctat ctcaaactcc caaccttaag 7020 ggatccgccc gtctcagcct cccaaagtgc tgagattaga ggcgtgagcc aaggcgccga 7080 gccgtatttt aaaagaaata atagataatg ctgagtgtat aatttcgggt gacagagaag 7140 ttctcactga tcaaataata cttgtgacct taatgaaaaa aatagatcaa cccctggaag 7200 attggcggaa ggattttcca cacagctgtc agccgtgaag gcacaaaggt gaaaacaatg 7260 ttatgtggaa ggaagaggct ctgcctgaaa tgctgggaat gacatgggga gaatgacaag 7320 acgactgtgg agagacagag agcactctgg gtacacagga aactaaggag gaacaaggag 7380 cgtgtgtttg atactcacag ccattggact tacctcgggg ctaactggga atccctacat 7440 gatgaatagt gactgacatg aaaataaggg aggcccaggt gcataactgg aatctaggag 7500 actgtggaaa aggcaattcc cgcccccctg gtgaaatgtg gtgctgattt agacactaaa 7560 tgaatgaaag atggacacaa gatgtgtttg tgaggtagag taatttgcag ggagggcttg 7620 cctggtttga tttttcctaa ttgtttaatc ttcacttcat tgatttcttt ctgagattta 7680 tttttcctac atgtaaatca atacttggca gaggagtgag agatacatga ggggtggtgc 7740 aaaggaagag acctattata atataacaca caaggttctg aacggtggct cacacctgta 7800 acccaacatt ttgggaggct gaggaggctg gatcaagtga gatcaggagt tcgagatcag 7860 cctggacaac atggtgaaac cccatctcta ctaaatatac aaaaactagc tgggggtggt 7920 ggcgcgtgcc tgtaatacca gctattcggg aagttgaaga aggagaatgg cttcaaccag 7980 ggagggagag gttacagtga gccaagatcg cgtcattgca ctgcacccta ggtgacagag 8040 tgagactcca tggcaaaaaa taaaaataaa gaatacataa atataatata acatacacga 8100 atgacaaagg cacaccaatt ccaatcatca tttttctatt tctctataat gacttctttg 8160 atcctttatc ctatccataa gaaaatcagg cgaaaacatc ttccttattt ggctttctgt 8220 gagcatgaga tcatatggaa aatgtgaaac ccaccagcac aggtcctgga atagagaacg 8280 tgatctgttc atggcacaaa acttgcccct tcacccaaat cccccacctc acccctactt 8340 ccaatcacat taatgataca gatagatcat ggggaggtaa aaactaatat tctttggagt 8400 tcagatcgta gactcagaga ccagtgccag cactatctcc tggtcacctt ttggagtaat 8460 tcacagaaag acaggctgta ttgaagcaac agatgatgga gggggtggtc tttcccccag 8520 actctcgggt ggaacagcag cctaatatct gactcccaag atgacaaaag tagcatgttg 8580 cccacgagct tcatcattat ttcctggctg tttgatataa gacagctcaa cctcacttat 8640 gttgatttca atgtcactgt tttttccttt tcttggagaa tgtaatttgt ttgagtcaag 8700 agggttgtgg atgtagaaac tgtaaagcac attcactgtg tatcaatccc agtccagtct 8760 tcccagagaa gactctaaac acctcccata ctgcacctgg gcctgtgcca atttctatca 8820 ctcaccatca ctccagggag acagaacaca cagggaatac attacatagg caggttcatt 8880 acttatagat aagcagcgag tgacaacaga aaccttcctt tcagggtgag ccagtccctc 8940 aaggctcaga aaaactgctc aggacacatg gagtcacttc atgtgcactg tagctggggg 9000 aagccagaaa gcagcccagc ctgggttttg taccctggag ccacagggaa cactcagcta 9060 aagcactgca tgatgttctc ctccaggaag aacaggaaga cagcccaggc tgttctgaga 9120 cgttcctcct gatctcagga tgttgctgtc ttagcctatt tttgttgcta taaaagaaca 9180 cttgagcctg ggtatcttct aaagaaaaga gatgtgtttg gctcactgat cggcacgctg 9240 tactagaagc aggacactac catctatttc tggctgcggc ctcaggctgc tcccacactg 9300 acagaagaga agggggtcct gcgtgtgcag agaccacaga gatcacatgg caagagaggg 9360 agaaaggggg tgtgatggag cttccaagct ctttttaaga atcaactctc cagggtacta 9420 atagagggag aacttgctaa acccgtcctc tggggacagc attaatctat tcatgatgga 9480 tccaccccca tgaccaaaac acccctccca ataggcacaa cctcccacac tggggattaa 9540 atttcaaagt ggggtttgga ggggtcaaac attgaaacaa tagcagttgt atcatcagca 9600 cattctattg ttattatgaa aactataacg gagaaagcag gagaaagctg ggtctcccgc 9660 ctcgtgggtg cttgtcctaa agaggtgttt tatgtggttg cctggcaacc aagaaatgag 9720 agacaatcca caaagaggaa ctgctatggt tagcttctta ttggattctc atcttcctcc 9780 aggtatcgcc agacacctgc atgctgtgat taggtactca gtggccatca tcctcttcac 9840 catccttccc ttctttctcc ttcatcgctg gtgctccaaa aaaaaaagta agcctcacga 9900 agcagaggcc agagaactca gggccctgtg cggaagcagg atgggagcac gcaggtgtgt 9960 gttcctcact ggcaggaaag tctctggccc aaggcaggag ccagaggcag agctttctag 10020 agagagcacc agacaccctg cccctgcctt cagctcacag accattgcct gattgtgaac 10080 tgtatcctca cgtcccctgc agccactcac atccaggaga agattccatg acaggcagaa 10140 agtgggagat agaatcaatg ggatgggaac tgacagctat tcatggaatg gggtcttgca 10200 ctcagagaga tggaatgtct gagtctggct gttggcagct gagggacctc aggcacctat 10260 ggcctccccc tgtgtgttgg tatctgttca tgaaatgagg acccagaagt gccctcccag 10320 ctgttttgat tgcttccgtc tcctacagat gctgctgtaa tgaaccaaga gcctgcggga 10380 cacagaacag tgaacaggga ggtaggtcct cctagcccag cctcatggat acagtcttat 10440 tccctaatag tcctgaaaaa tgtgaacacc ctccctcact caggatttcc ctctctccag 10500 gactctgatg aacaagaccc tcaggaggtg acatacgcac agttggatca ctgcattttc 10560 acacagagaa aaatcactgg cccttctcag aggagcaaga gaccctcaac agataccagc 10620 gtgtgtatag aacttccaaa tgctgagccc agagcgttgt ctcctgccca tgagcaccac 10680 agtcaggcct tgatgggatc ttctagggag acaacagccc tgtctcaaac ccagcttgcc 10740 agctctaatg taccagcagc tggaatctga aggcgtgagt ctccatctta gagcatcact 10800 cttcctcaca ccacaaatct ggtgcctctc tcttgcttac caatgtctaa ggtccccact 10860 gcctgctgca gagaaaacac actcctttgc ttagcccaca attctctatt tcacttgacc 10920 cctgcccacc tctccaacct aactggctta cttcctagtc tacttgaggc tgcaatcaca 10980 ctgaggaact cacaattcca aacatacaag aggctctctc ttaacacggc acttagacac 11040 gtgctgttcc accttccctc gtgctgttcc acctttcctc agactatttt tcagccttct 11100 ggcatcagca aaccttataa aatttttttg atttcagtgt agttctctcc tcttcaaata 11160 aacatgtctg ccttcat 11177 //