Dbfetch
ID HLA00937; SV 2; standard; DNA; HUM; 3822 BP. XX AC HLA00937; XX SV HLA00937.2 XX DT 30-JAN-1996 (Rel. 1.1.0, Created, Version 1) DT 16-JAN-2024 (Rel. 3.55.0, Last Updated, Version 2) XX DE HLA-E*01:03:02:01, Human MHC Class I sequence XX KW Human MHC; HLA; Class I; HLA-E; Allele; HLA-E*01:03:02:01; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-IMGT/HLA Release Version 3.55.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD-IMGT/HLA Database, Distributed under the Creative CC Commons Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/imgt/hla/licence/ for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-3822 RX PUBMED; 9154460. RA Gomez-Casado E, Martinez-Laso J, Vargas-Alarcon G, Varela P, Diaz-Campos N, RA Alvarez M, Alegre R, Arnaiz-Villena A; RT "Description of a new HLA-E (E*01031) allele and its frequency in the RT Spanish population."; RL Human Immunology 54:69-73(1997). XX RN [2] RP 1-3822 RX PUBMED; 15140828. RA Stewart CA, Horton R, Allcock RJ, Ashurst JL, Atrazhev AM, Coggill P, RA Dunham I, Forbes S, Halls K, Howson JM, Humphray SJ, Hunt S, Mungall AJ, RA Osoegawa K, Palmer S, Roberts AN, Rogers J, Sims S, Wang Y, Wilming LG, RA Elliott JF, de Jong PJ, Sawcer S, Todd JA, Trowsdale J, Beck S; RT "Complete MHC haplotype sequencing for common disease gene mapping."; RL Genome Research 14:1176-1187(2004). XX RN [3] RP 1-3822 RX PUBMED; 16570139. RA Pyo CW, Williams LM, Moore Y, Hyodo H, Li SS, Zhao LP, Sageshima N, RA Ishitani A, Geraghty DE; RT "HLA-E, HLA-F, and HLA-G polymorphism: genomic sequence defines haplotype RT structure and variation spanning the nonclassical class I genes."; RL Immunogenetics 58:241-251(2006). XX RN [4] RP 1-3822 RX PUBMED; 18193213. RA Horton R, Gibson R, Coggill P, Miretti M, Allcok RJ, Almeida J, Forbes S, RA Gilbert JGR, Halls K, Harrow JL, Hart E, Howe K, Jackson DK, Palmer S, RA Roberts AN, Sims S, Stewart CA, Traherne JA, Trevanion S, Wilming L, Rogers RA J, de Jong PJ, Elliott JF, Sawcer S, Todd JA, Trowsdale J, Beck S; RT "Variation analysis and gene annotation of eight MHC haplotypes: The MHC RT Haplotype Project."; RL Immunogenetics 60:1-18(2008). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC WHO Nomenclature Committee for Factors of the HLA System. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; AF523274; AF523274.1. DR EMBL; AF523278; AF523278.1. DR EMBL; AF523280; AF523280.1. DR EMBL; AL662873; AL662873.3. DR EMBL; AY645727; AY645727.1. DR EMBL; AY645737; AY645737.1. DR EMBL; AY645740; AY645740.1. DR EMBL; AY645741; AY645741.1. DR EMBL; CR382280; CR382280.5. DR EMBL; L79943; L79943.1. DR EMBL; X87680; X87680.1. DR EMBL; X87681; X87681.1. XX FH Key Location/Qualifiers FH FT source 1..3822 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="African descent, Asian, European" FT /cell_line="1416-1194" FT /cell_line="1416-1195" FT /cell_line="17771" FT /cell_line="CHI004" FT /cell_line="HAN19-01" FT /cell_line="HAN19-04" FT /cell_line="HAN19-05" FT /cell_line="JHUAA0393" FT /cell_line="JHUAA0396" FT /cell_line="MOU" FT /cell_line="MSC" FT /cell_line="MT14B" FT /cell_line="PGF" FT /cell_line="SCHU" FT /cell_line="WDV" FT CDS join(301..364,495..764,1009..1284,1906..2181,2306..2422, FT 3173..3205,3310..3350) FT /codon_start=1 FT /gene="HLA-E" FT /allele="HLA-E*01:03:02:01" FT /product="MHC Class I HLA-E*01:03:02:01 sequence" FT /translation="MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFIS FT VGYVDDTQFVRFDNDAASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRG FT YYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQI FT SEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATL FT RCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCH FT VQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGS FT YSKAEWSDSAQGSESHSL" FT UTR 1..300 FT exon 301..364 FT /number="1" FT intron 365..494 FT /number="1" FT exon 495..764 FT /number="2" FT intron 765..1008 FT /number="2" FT exon 1009..1284 FT /number="3" FT intron 1285..1905 FT /number="3" FT exon 1906..2181 FT /number="4" FT intron 2182..2305 FT /number="4" FT exon 2306..2422 FT /number="5" FT intron 2423..3172 FT /number="5" FT exon 3173..3205 FT /number="6" FT intron 3206..3309 FT /number="6" FT exon 3310..3352 FT /number="7" FT intron 3353..3517 FT /number="7" FT exon 3518..3522 FT /number="8" FT UTR 3523..3822 SQ Sequence 3822 BP; 772 A; 1077 C; 1103 G; 870 T; 0 other; caaagtgctg agattacagg cgtgagccac cgcgcccagc caggactaat ttctaagagt 60 gtgcagagat accgaaacct aaaagtttaa gaactgctga ttgctgggaa actctgcagt 120 ttcccgttcc tctcgtaacc tggtcatgtg tccttcttcc tggatactca tgacgcagac 180 tcagttctca ttcccaatgg gtgtcgggtt tctagagaag ccaatcagcg tcgccacgac 240 tcccgactat aaagtcccca tccggactca agaagttctc aggactcaga ggctgggatc 300 atggtagatg gaaccctcct tttactcctc tcggaggccc tggcccttac ccagacctgg 360 gcgggtgagt gcggggtcgg gatggaaacg gcctctaccg ggagtagaga ggggccggcc 420 cggcgggggc gaaggactcg gggagccgcg ccgggaggag ggtcgggccg atctcagccc 480 ctcctcgccc ccaggctccc actccttgaa gtatttccac acttccgtgt cccggcccgg 540 ccgcggggag ccccgcttca tctctgtggg ctacgtggac gacacccagt tcgtgcgctt 600 cgacaacgac gccgcgagtc cgaggatggt gccgcgggcg ccgtggatgg agcaggaggg 660 gtcagagtat tgggaccggg agacacggag cgccagggac accgcacaga ttttccgagt 720 gaatctgcgg acgctgcgcg gctactacaa tcagagcgag gccggtgagt gaccccggcc 780 aggggagcag gtcacgaccc ctccccatcc cccacggacg gcgcgggtcc cctcgaatct 840 tcgggtccca gattcacccc aaggctgcgg aacccgccca gaccctagac cggggagagt 900 ctcaggcgcc tttacccggt tctttttcag tttaggccaa aatgcccaca gggtggtggc 960 gacgggggcg gggcttggtg ggcgggactg actaaggggc ggggccaggg tctcacaccc 1020 tgcagtggat gcatggctgc gagctggggc ccgacgggcg cttcctccgc gggtatgaac 1080 agttcgccta cgacggcaag gattatctca ccctgaatga ggacctgcgc tcctggaccg 1140 cggtggacac ggcggctcag atctccgagc aaaagtcaaa tgatgcctct gaggcggagc 1200 accagagagc ctacctggaa gacacatgcg tggagtggct ccacaaatac ctggagaagg 1260 ggaaggagac gctgcttcac ctgggtaaga gggtccacag ggctactctc ccatctcctt 1320 cttgggctag gactgtgccc acagctgaca gacctcaaac agtagaagaa acagggatgg 1380 aggccagaat accactcctc ccttggatca ggagagggag ctgtcacctg aggtacagga 1440 gatcctatac cacagagtga ctctcttaaa gggccagacc tctctcaggg gcaattaagg 1500 aatctagtct cgctggagat tccatccttc agatgaactg atgagcagtt ctctttgact 1560 cccagtatta ggaatcacgg gggagtttct ctcgtgcctg attctcagcc ccacaccaag 1620 agtttttgga ggtctgactc cagcttttct cagtcactca gcatccacac aggccaggac 1680 cagaaatccc ttttcacctt ctaccctggg ctagctcatc ccgattctag aactttccaa 1740 ggaataagag gctatcccag atccctaagt ccaggctggt gtcaaggttt tgtcctcttc 1800 tcctactata attgtcctct tccttctcag gatggtcaca tgggtgctgc tggagtgtcc 1860 catgagagat acaaagtgcc tgaattttct gactcttccc ctcagagccc ccaaagacac 1920 acgtgactca ccaccccatc tctgaccatg aggccaccct gaggtgctgg gccctgggct 1980 tctaccctgc ggagatcaca ctgacctggc agcaggatgg ggagggccat acccaggaca 2040 cggagctcgt ggagaccagg cctgcagggg atggaacctt ccagaagtgg gcagctgtgg 2100 tggtgccttc tggagaggag cagagataca cgtgccatgt gcagcatgag gggctacccg 2160 agcccgtcac cctgagatgg agtaaggagg gggatgggag gtcatgtctc ttctcaggga 2220 aagcgggagc ccttctggag cccttccgca gggtcagggc tgaggcctgg gggtcagggc 2280 cccttacgtt cccctctttt cccagagccg gcttcccagc ccaccatccc catcgtgggc 2340 atcattgctg gcctggttct ccttggatct gtggtctctg gagctgtggt tgctgctgtg 2400 atatggagga agaagagctc aggtggggaa gggagaaggg tggggtctga gttttcttgt 2460 cccactgggt gtttcaagcc ctaggtaaaa gtgtgtcctg cctcgttact gggaagcacc 2520 atccacacac acgagcctac ccagcctggg gccctgtgtg ccagcaccta ctcttttttt 2580 ttgagacgga gtcttggctc tgtcacccag gctggagtgc aatggcgtgg tttcagctca 2640 ctgcaacctc cgcctcccag gttcaagcaa ttctcctgcc tcagcctccc tagtagctgg 2700 gactacacat gcgtgccacc acacctggct aatttttttt tttgtatttt tagtggagat 2760 ggggtttcac tatgttggcc aggctggtct cgaactcctg actttgtgat ctgcctgcct 2820 cggcctccca aagtgctggg attacagtcg tgagccaccg cacccagccg cacctactct 2880 tttgtaaagc acctgtgaca atgaaggaca gatttatcac cttgacgatt gtggtgatgg 2940 ggacctgatc ccagcagtca caggtcacag gggaaggtcc ctgctgaaga cagacctcag 3000 aagggcagtt gatccaggac ccacacctgc tttcttcacg tttcctgatc ctgccctggg 3060 tctgcagtca cagttcagga aacttctctg ggatccaaaa ctaggaggtt cctctaggac 3120 cttatggccc tgcctcctcc ctggcccctc acaggacatt ttcttccaac aggtggaaaa 3180 ggagggagct actctaaggc tgagtgtaag tgcggggcgg gagcgtggag gagctcgccc 3240 accctataat tcctcctgca ccacatctcc tgtgggctct gaccaggtct tgtttttgtt 3300 ctaccccagg gagcgacagt gcccaggggt ctgagtctca cagcttgtaa aggtgagatt 3360 ctgggggtct gaagtgggtg gagggtgggg cagaggggac aggactgggt tgtggggatt 3420 ttttgattca gaatttttga gtgtgtggtg ggctgttcag agtgtcatca cttaccgtga 3480 ctgacctgaa tttgttcatg actattttct tctgtagcct gagacagctg ccttgtgtgc 3540 gactgagatg cacagctgcc ttgtgtgcga ctgagatgca ggatttcctc acgcctcccc 3600 tatgtgtctt aggggactct ggcttctctt tttgcaaggg cctctgaatc tgtctgtgtc 3660 cctgttagca caatgtgagg aggtagagaa acagtccacc tctgtgtcta ccatgacccc 3720 cttcctcaca ctgacctgtg ttccttccct gttctctttt ctattaaaaa taagaacctg 3780 ggcagagtgc ggcagctcat gcctgtaatc ccagcactta gg 3822 //